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      • 痛症에 대한 樣態別 辨證分型 硏究

        成彊慶 圓光大學校 韓醫學硏究所 1997 원광한의학 Vol.7 No.1

        다양하게 표현된 痛症을 樣態別로 살펴보고 樣態에 따라 주로 發顯된 部位와 病因 및 病性을 考察하여 病症에 대한 辯證分型을 제시해보고자 東醫寶鑑에 나타난 病症을 中心으로 考察하여 다음과 같은 結論을 얻었다. 1. 病症의 樣態는 40종이었다. 2. 病症은 樣態에 따라 일정한 部位에 發顯되었다. 3. 病症의 樣態와 病因의 性質은 연계성이 있었다. 4. 部位에 따라 나타나는 病症의 樣相은 다양하지만 그들의 病性은 同一性을 公有하고 있었다. In the view of diagnostic principles of Oriental medicine that estabilished on the basis of Byun Jeung Ron(辯證論) with which doctors fine the common property in the revelation of phenomenon and understand the nature of disease, a pain is reconized as not only a simplified symptom but also important basic data for the diagnosis of the etiological cause and nature of disease. I would like to state my opinion on pain nature through the bibilographic study of Dong Eu Bo Gam(東醫寶鑑). 1. Based on nature, a pain is classified into 40 types. 2. All pains have each defined regions which appears their symptom and sign 3. The cause of disease that reveals each pain is various. 4. The aspect of pain in external manifestation is various, but the pain of same revelation spot has the same quality of pain in common.

      • 人體構造에 대한 五行論的 模型硏究

        成疆慶 圓光大學校 韓醫學硏究所 1996 원광한의학 Vol.6 No.1

        As a result of our studies on the phenomenon of life in the point of the five elements theory, we have aquired a few conclusion as follows; 1. The phenomenon of life is composed of four elements {essene of life(精), qi(氣), vitality(神), blood(血)}. 2. Five viscera(五臟) is a conception which is indicated five funtional properties of the phenomenon of life. 3. The phenomenon of life can be analized by five functional systems. 4. Body is composed of tendons(筋), channels and vessels(脈), muscles(筋肉), skin and hairs(皮毛) and bones(骨).

      • 溫膽湯 煎湯液이 家兎의 心血管系에 미치는 影響

        成彊慶,文炳淳,朴暎淳,金世吉 圓光大學校 韓醫學硏究所 1994 원광한의학 Vol.4 No.1

        The present experiments were designed to investigate the effects of Ondamtang water extract(Ondamtang) on the blood circulation, bile acid secretion and mental tension in normal and hyperlipidemia induced rabbits. In order to control the precise chemical and physical conditions, the experimental rabbits were supplied with calorie limited food, and the hyperlipidemia rabbits were induced by oral administration of cholesterol(500㎎/㎏) for 3 weeks. The results obtained were summerized as follows: 1. Ondamtang increased the bile secretion and serum bile acid level in rabbits. 2. Bile solution decreased the blood pressure after injection through the ear vien in rabbits. 3. The blood pressure was decreased after injecting Ondamtang through the ear vein. And it was also decreased after oral administration of Ondamtang for 5 days. 4. The decrease of blood pressure was not dependant on the autonomic nervous system. 5. Ondamtang activated the Mg^2+ -Ca^2+ -ATPase activity of cardiac indoplasmic reticulum, and thus inhibited the cardiac muscle contraction. 6. Ondamtang stimulated the dilatation of the peripheral blood vessel. 7. Ondamtang decreased the serum creatinine level by stimulating the renal filtration and thus it increased the kidney function in hypelipidemia rabbits. 8. Ondamtang decreased the arteriosclerosis index by effecting the metabolism of cholesterol and lipid in hypdrlipidemia induced rabbits. 9. Ondamtang inhibited the Na^+ -K^+ -ATPase activity of the cerebral cortex, and decreased the sensitivity of the electrical shock. According to the above results, Ondamtang improved blood circulation by dilatation the capillary lumen and decreasing in blood viscosity, promoted bile acid secretion, inhibited the nerve transmission, and relieved the mental tension.

      • 프랙탈 코딩 파라미터를 이용한 디지털 영상 워터마킹

        고성식,조강석,정용덕,김정화 조선대학교 전자정보통신연구소 2003 電子情報通信硏究所論文誌 Vol.6 No.1

        In this paper we propose new watermarking method that a secret key is created from image contents without inserting an watermark in the image contents and the watermark is transformed to the fractal parameters Image logo watermark uses the owner photograph of the image contents and after image watermark is transformed t o the fractal parameter between domain and range of the watermark logo by using fractal theory, the fractal parameter is scrambled by the created secret key Thus, our algorithm proposed in this paper has no image distortion by an watermarking because of decoding the watermark by the created secret key Experimental results have shown that the proposed method achieves improved robustness with respect to image lossy compression, cropping attacks and various filtering attacks.

      • KCI등재

        체내 납부담의 지표로서 누적 혈중 납량과 누적 혈중 ZPP가 납 관련 신기능에 미치는 영향

        윤강호,김남수,김진호,김화성,이병국 대한산업의학회 2006 대한직업환경의학회지 Vol.18 No.4

        목적: 체내 납부담의 지표로서 누적 혈중 납량과 누적 혈중 ZPP가 납관련 신기능에 미치는 영향을 알아보기 위하여 678명의 납 작업자들을 대상으로 본 연구를 시도하였다. 방법: 누적 혈중 납량과 누적 혈중 ZPP는 입사시부터 매 1년간의 혈중 납량과 혈중 ZPP를 누적하여 구하였다. 입사시기가 1983년 이전인 납 작업자의 경우는 최초 혈중 납량과 최초 혈중 ZPP를 그 이전의 값으로 추정하여 구하였다. 체내 납부담의 지표로서 골중 납량과 DMSA착화납량을 측정하였으며, 최근의 납 노출 지표로서는 혈중 납량과 혈중 ZPP를 측정하였다. 신기능을 평가하는 지표로서는 임상 신기능 지표로서 BUN과 혈청 creatinine을 측정하였고, 신기능 조기지표로는 NAG (N-acetyl-D- glucosamide)와 RBP (Retinol binding protein)를 측정하였다. 결과: 혈중 납량과 혈중 ZPP의 누적지수와 골중 납량과는 결정계수(r²)는 각각 0.72와 0.567로서 유의한 상관이 있었으며 이들 누적지수와 골중 납량은 곡선형적 모델이 더 적합하였다. 신기능 지표들을 종속변수로 하고 성, 연령, 직력 및 음주와 흡연을 통제한 후 혈중 납량과 혈중 ZPP를 독립변수로 한 중회귀분석에서 혈중 납량은 4개의 신기능 지표들 중 지수 변환한 NAG와만 유의한 관련이 있는 반면, 혈중 ZPP는 지수변환한 NAG를 제외한 신기능 지표들과 유의한 관련이 있었다. 한편 신기능 지표들을 종속변수로 하고 연령 및 직력과 음주와 흡연을 통제한 후 체내 납 부담노출지표들을 독립변수로 한 중회귀분석에서 골중 납량과 혈중 ZPP 누적지수는 4개의 신기능 지표들과 유의한 관련이 있는 반면, DMSA 착화납량과 혈중 납량 누적지수는 BUN을 제외한 신기능 지표들과 유의한 관련이 있었다. 결론: 상기한 결과로 보아 혈중 납량과 혈중 ZPP의 누적지수는 체내 납부담의 지표로서 효용성이 입증되었으며, 특히 혈중 ZPP의 누적지수가 혈중 납량의 누적지수보다 체내 납부담의 대리지표로서 더 좋은 것으로 나타났다. Objective: To evaluate the possibility of cumulative blood lead and blood ZPP as surrogates of lead body burden and to investigate their association with renal function as an index of lead body burden. Methods: The study subjects comprised 678 lead workers with past blood lead and blood ZPP data from their employment. Cumulative blood and ZPP were calculated by accumulating the every year mean value of both indices from the new employment since 1983. To assess the cumulative data of lead workers who started their lead work before 1983, the years before 1983 were simulated with the first available data from 1983. Study variables for lead body burden were tibia bone lead and DMSA chelatable lead, whereas those for current lead biomarkers were blood lead and blood ZPP. BUN and serum creatinine were selected as clinical renal biomarkers, while NAG (N-acetyl-D-glucosamine) and RBP (Retinol binding protein) were selected as early renal biomarkers. Results: The association between cumulative blood lead and blood ZPP with tibia bone lead was statistically significant with determinant coefficients (r²) of 0.72 and 0.567, respectively, and their relationships were better explained by the curvilinear regression model. In multiple regression analysis of current lead biomarkers on the renal biomarkers after controlling for possible confounders (age, sex, job duration, smoking and drinking status), blood lead was associated only with log-transformed NAG, whereas blood ZPP was associated with 3 other renal biomarkers. On the other hand, in multiple regression analysis of biomarkers of lead body burden on renal biomarkers after controlling for possible confounders (age, sex, job duration, smoking and drinking status), cumulative blood ZPP and tibia bone lead were associated with all 4 renal function biomarkers, whereas cumulative blood lead and DMSA chelatable lead were associated with 3 renal biomarkers except BUN. Conclusion: Cumulative blood and ZPP were demonstrated to be good surrogates of lead burden. Furthermore, the cumulative blood ZPP was confirmed to have a better association than the cumulative blood lead.

      • 定癎丸의 抗癎疾性 效果에 대한 實驗的 硏究

        李相官,文炳淳,成彊慶 한국전통의학연구소 1997 한국전통의학지 Vol.7 No.2

        이 실험은 정간환의 진경효과,강온효과,진통효과,진정효과, GABAergic SYSTEM에 미치는 영향 등을 조사하기 위한 것으로 아래와 같은 결론을 얻었다. 1. 정간환 추출액은 strychine에 의해 유발된 경련의 유발 시간을 연장시켰다. 2. 정간환 추출액은 ECT unit의 전기충격에 의해 유발된 경련으로 인한 사망시간을 연장시켰다. 3. 정간환 추출액은 정상체온 및 endotoxin에 의해 유발된 발열에 대해 강온효과가 있었다. 4. 정간환 추출액은 acetic acid 주입에 의한 진통실험에서 writhing syndrome의 횟수를 감소시켰다. 5. 정간환 추출액은 자발운동을 감소시켰다. 6. 정간환 추출액은 뇌의 GABA-T의 활성을 감소시켰다. 7. 정간환 추출액은 뇌의 GABA 활성농도를 증가시켰다. 8. 정간환 추출액은 뇌의 GAD 활성도를 증가시켰다. This study has been carried out to investigate the effects of Jeonggan hwan(JGH) extracts on anti-convulsive, antipyretic, analgesic, sedative and GABAergic system of experimental animals. The results of this study were as follows: 1. JGH extract prolonged significantly the beginning time to convulsion and death induced by strychnine. 2. JGH extract prolonged significantly the time to death induced by electrical shock of ECT unit,(3 sec, 200 F, 25 mA) 3. On the experiment of hypothermic effects of JGH extract on the rectal temperature of mice, JGH extract decreased significantly the rectal temperature of mice 4. On the experiment of antipyretic effects of JGH extract on the febrile induced by the subcutaneous injection of 150 ㎍/㎏ endotoxin in mice, JGH extract decreased significantly the rectal temperature of mice. 5. On the experiment of analgesic effects of JGH extract on the writhing syndrome induced by intraperitoneal injection 0.7% acetic acid 1 ml/100g in mice, the writhing syndrome induced by acetic acid was reduced significantly by administration of JGH extract. 6. On the experiment of effects of JGH extract on spontaneous motor activity measured by wheel cage method in mice, the spontaneous motor activity was reduced significantly by administration of JGH extract . 7. On the experiment of effects of JGH extract on the activity of GABA - transaminase (GABA-T) in mouse brains after 21 days of oral administration of JGH extract, the activity of GABA-T was reduced significantly by administration of JGH extract. 8. On the experiment of effects of JGH extract on the activity concentration of GABA in mouse brain after 21 days of oral administration of JGH extract, the activity concentration of GABA was reduced significantly by administration of JGH extract. 9. On the experiment of effect of JGH water extract on the activity of GAD in mouse brains after 21 days of oral administration of JGH extract, the activity of GAD was reduced significantly by administration of JGH extract. According to the these results, Jeongganhwan extracts reveal the effects on the anti-convulsive, antipyretic, analgesic, sedative and GABAergic system.

      • 폴리우레탄을 이용한 Thiobacillus sp. IW의 고정화

        황은상,이광우,박돈희 전남대학교 촉매연구소 2001 觸媒硏究 論文集 Vol.22 No.-

        The immobilization of Thiobacillus sp. IW, the hydrogen sulfide removing bacterium, was studied by using the adsorption and physical capture methods. In the case of immobilization by the adsorption, the type, size, and amount of polyurethane foam were affected by the cell immobilization capacity of supporter. Among supporters, MC-70 was better immobilizing material. The optimum size and amount of polyurethane foam were 5∼8mm and 8g/L, respectively. In the case of immobilization by the physical capture, polyurethane foam could be prepared with the same ratio of modified MDI prepolymer, polyol, and medium with better condition. The optimum size and amount of polyurethane foam were 6∼7mm and 8g/L, respectively. Considering the cell immobilization capacity, the immobilization by physical capture was more effective than the immobilization by adsorption. The immobilization intensity by adsorption was 85% after shaking for 24hrs, whereas the immobilization by physical capture was 92% under the same condit

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