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        동일 지명의 형성 과정 고찰: 전북의 성수면과 성수산을 사례로

        조성욱 ( Sung Wook Cho ) 한국지리학회 2015 한국지리학회지 Vol.4 No.1

        본 연구에서는 전라북도 진안군과 임실군에 존재하는 2개의 성수면과 3개의 성수산의 형성과정을 중심으로 동일 지역에서 같은 지명이 부여되는 과정과 특징을 살펴보았다. 본 연구에서 밝혀진 내용을 정리하면 다음과 같다. 첫째, ‘성수(聖壽)’라는 지명은 임실 성수산 상이암의 이성계 관련 전설에서 유래했으며, 그 시기는 1394년 이후로 추정된다. 둘째, 3개의 성수산 중에서 가장먼저 명명된 것은 임실 성수산으로 보이며, 백운면 성수산과 성수면 성수산은 그 이후로 보인다. 시기는 1700년대 이전으로 볼 수 있다. 역사적인 측면에서는 상이암이 위치하는 임실 성수산(876m), 지리적 측면에서는 금남호남정맥 상에 위치하고 해발고도가 가장 높은 백운면 성수산(1,059m)이 상징성을 지닌다. 셋째, 성수산이라는 산명이 먼저 존재하고, 1914년 행정 구역개편 시기에 성수면이 등장했다. 임실 성수면은 임실군 성수산(876m)에서 유래했고, 진안군 성수면은 성수면 내에 위치하는 성수산(482m)에서 유래했다. This research looks at the process and features of taking the same geographical names in the small region by focusing on formation process of two ‘Sungsu-Myeon’ and three ‘Mountain Sungsu’ present in Imshil and Jinan Gun district. The research results are as follows. First, the nomination of ‘Holy Life (聖壽)’ was derived from the legend of related Yi-dynasty at Sang-i temple located in Imshil Mt. Sungsu, and the naming time might be estimated since 1394. Second, the first named it among the three Mt. Sungsu seen as Imshil Mt. Sungsu, and Baek-un Myeon’s Mt. Sungsu and Sungsu Myeon’s Mt. Sungsu are after that. That naming time can be seen before 1700s. They have the symbolic features which are Imshil Mt. Sungsu (876 m) in the historical aspect, and Baek-un Mt. Sungsu (1,059 m) in the geographical aspect. Third, Mt. Sungsu is the presence in the first, and appeared Sungsu Myeon as a new administrative district in 1914. Imshil Sungsu Myeon had originated in Imshil Mt. Sungsu (876 m) and Jinan Sungsu Myeon was derived from Mt. Sungsu (482 m) located in Sungsu Myeon.

      • KCI등재후보

        소아에서 간질발작의 임상양상과 뇌파검사의 관계

        이승현(Seung Hyeon Lee),손동우(Dong Woo Son),은병욱(Byung Wook Eun),심소연(So Yeon Sim),최덕영(Deok Young Choi),선용한(Yong Han Sun),조강호(Kang Ho Cho0, 류 일(Eell Ryoo),전인상(In Sang Jeon0, 차 한(Hann Tchah) 대한소아신경학회 2009 대한소아신경학회지 Vol.17 No.2

        목적:발작의 분류는 발작의 원인, 예후를 추정하거나 항경련제를 선택하는 데 있어 매우 중요하며 뇌파검사는 발작의 종류를 구분하고 적절한 치료를 하기 위해 시행하는 중요한 검사이다. 저자들은 소아에서 임상적 발작이 확실한 경우 간질발작의 임상양상과 뇌파검사 간의 일치 정도를 알아보고자 한다. 방법:2000년 1월 1일부터 2008년 9월 30일까지 1회 이상의 간질발작을 주소로 가천의대 길병원 소아청소년과에 방문한 환자 중 본원에서 처음으로 뇌파검사를 시행한 환자를 대상으로 하였다. 발작의 임상양상은 목격자와 본인의 설명을 기록한 의무기록지를 기준으로 하여 부분발작과 전신발작으로 분류하였고 뇌파검사는 발작간간질양방전을 기준으로 정상과 비정상으로 분류하였으며 각성과 수면상태 모두에서 시행하였다. 결과:총 461명의 환자의 뇌파검사 시의 평균 연령은 6.7세였고 남자는 247명, 여자는 214명이었다. 전체 환자에서 발작의 임상양상은 부분발작이 310명, 전신발작이 187명이었다. 각성뇌파검사에서 비정상은 158명으로 부분발작파가 118명, 전신발작파가 59명, 두 가지 발작파가 한 환자에서 나온 경우가 19명이었고, 수면뇌파검사에서는 비정상이 239명으로 부분발작파가 196명, 전신발작파가 77명, 두 가지 발작파가 한 환자에서 나온 경우가 34명이었으며 전체 환자에서는 비정상이 273명으로 부분발작파가 216명, 전신발작파가 97명, 두 가지 발작파가 한 환자에서 나온 경우가 40명이었다. 간질증후군은 전체 환자 중 90명에서 관찰되었다. 146명(41.5%)의 부분발작과 44명(23.4%)의 전신발작 및 79명(87.8 %)의 간질증후군이 뇌파소견과 일치하였다. 결론:영유아 및 소아에 있어 발작을 진단할 때에는 발작양상 분 아니라 정확한 뇌파소견을 세심하게 고려하여야 한다. Purpose:Electroencephalography(EEG) is an essential method carried out for classifying seizures and taking appropriate treatment. The aim of this study is to investigate the concordance between clinical findings of epileptic seizures and EEG in children. Methods:We enrolled 461 patients from those who visited Gil hospital from January 1, 2000 to September 30, 2008 with the chief complaint of epileptic seizure more than once and checked their first EEG at the same hospital. The clinical findings of seizure were based on the charts and interictal waking and sleep EEGs were done. Results:The mean age of the patients was 6.7 years old. 497 epileptic seizures occurred and its clinical finding included 310 of partial seizures and 187 of generalized seizures. In 315 waking EEG 158 were abnormal including 118 of partial seizures, 59 of generalized seizures and 19 of both seizures, in 431 sleep EEG 239 were abnormal including 196 of partial seizures, 77 of generalized seizures and 34 of both seizures, and in waking and/or sleep EEG 273 were abnormal including 216 of partial seizures, 97 of generalized seizures and 40 of both seizures. Epileptic syndromes were observed in 90 patients. 146(41.5%) of partial seizures, 44(23.4%) of generalized seizures, and 79(87.8%) of epileptic syndromes accorded with EEG. Conclusion:When diagnosing seizures in children, we must consider not only clinical findings but also accurate EEG findings.

      • SCOPUSKCI등재
      • P082 : Use of ustekinumab for treatment of moderate to severe psoriasis in Korea

        ( Sung Min Park ),( Gun Wook Kim ),( Hyun Ho Cho ),( Won Jeong Kim ),( Je Ho Mun ),( Margaret Song ),( Hoon Soo Kim ),( Hyun Chang Ko ),( Moon Bum Kim ),( Byung Soo Kim ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2

        Background: Ustekinumab, a fully human monoclonal immunoglobulin antibody that targets the interleukin (IL)-12 and IL-23 shared P40 subunit, has emerged as a promising treatment for moderate to severe psoriasis. However, to date, there are no ‘real-world’ data on ustekinumab in Korean patients with psoriasis. Objectives: To assess the clinical efficacy and safety of ustekinumab in Korean patients with psoriasis. Methods: Retrospective data was gathered during the follow-up of 31 consecutive psoriasis patients treated with ustekinumab for minimum of 16 weeks at single referral centre. Patients’ age, gender, Psoriasis Area Severity Index (PASI) score, physicians’ global assessment (PGA), concomitant therapies, and adverse events were reviewed. Results: Thirty-one patients (median age 42.7) had been treated with ustekinumab. Twenty-three of 31 patients (74.2%) had obtained near complete clearance (PASI 90) upon the final follow-up visit, and PASI90 was achieved after an average of 2 administration of ustekinumab. Concomitant systemic treatments, primarily methotrexate, were given to 7 (22.5%) patients. Three patients (9.7%) discontinued treatment, primarily for sub-optimal response or loss of response. No unexpected adverse events other than herpes zoster and elevated liver enzyme were observed. Conclusion: Ustekinumab can be of benefit in the treatment of Korean psoriasis patients, as it was associated with a rapid and satisfactory response and was well tolerated.

      • Predictors of Major Clinical Adverse Events in Genotype 1 Hepatitis C Patients Receiving Direct-Acting Antiviral Therapy: A Multicenter Cohort Study

        ( Sung Won Lee ),( Hae Lim Lee ),( Nam Ik Han ),( Hee Yeon Kim ),( Chang Wook Kim ),( Chan Ran You ),( Sang Wook Choi ),( Se Hyun Cho ),( Joon-Yeol Han ),( Do Seon Song ),( U Im Chang ),( Jin Mo Yang 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

        Aims: The aim of this study was to determine the factors associated with the development of major clinical adverse events in genotype 1 hepatitis C virus (HCV) infected Korean patients who received direct-acting antiviral (DAA) therapy in real clinical settings. Methods: A total of 648 genotype 1 HCV infected patients who received DAA therapy between May 2016 and January 2018 at the liver units of the Catholic University of Korea were analyzed. Primary endpoints were hepatic decompensation and/or treatment discontinuation due to adverse events and the development of de novo hepatocellular carcinoma (HCC). Results: The median follow-up period was 12.8 months (range, 1.3~34.8). 70.7% of the patients had chronic hepatitis and 29.3% compensated cirrhosis. Treatment discontinuation due to adverse events occurred in 2.8% (18/648), hepatic decompensation in 1.4% (9/648) and de novo HCC developed in 3.1% (19/620) of the patients. In multivariate analysis, baseline platelet count less than 150,000/㎣ (P=0.022), estimated glomerular filtration rate (eGFR) less than 50 mL/min/1.73㎡ (P=0.037) and baseline serum albumin less than 3.5g/dL (P=0.035) were independently associated with hepatic decompensation and/or treatment discontinuation due to adverse events. Also, platelet count less than 150,000/㎣ was independently associated with the development of de novo HCC (P=0.048). Conclusions: Patients with low platelet count and serum albumin level, which are indicators of portal hypertension, and patients with renal impairment were more likely to experience hepatic decompensation and/or treatment discontinuation due to adverse events. Low platelet count was associated with de novo HCC development. These patients should be meticulously followed up during and after the DAA therapy.

      • Poster Session:PS 1176 ; Cardiology : Long-Term Prognostic Value of Coronary Computed Tomography Angiography and Exercise ECG in Relation to Symptomatic Status in Patients with Suspected Coronary Artery Disease

        ( Sang Eun Lee ),( Hyuk Jae Chang ),( Ji Hyun Yoon ),( In Jeong Cho ),( Chi Young Shim ),( Geu Ru Hong ),( Young Jin Kim ),( Byoung Wook Choi ),( Nam Sik Chung ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: To explore the prognostic performance of coronary computed tomography angiography (CCTA) and exercise electrocardiography (XECG) in patients with suspected coronary artery disease (CAD) in relation to symptomatic status. Methods: We retrospectively enrolled 3,456 (58±9 years, 52% male) patients with atypical chest pain (n=2,269) or asymptomatic patients (n=1,188) who had undergone concurrent CCTA and XECG from 2003 through 2009. Patients were followed-up for major adverse cardiac events (MACE): cardiac death, acute coronary syndrome, and revascularization after 90 days from index CCTA. Results: During a mean follow-up of 3. 3±1. 4 years, 67 MACEs were observed. According to the Diamond-Forrester criteria, all asymptomatic patients had very low-tolow pre-test probability of CAD while 77. 9% of patients with atypical chest pain had intermediate probability. After risk adjustment, XECG independently predicted MACE in patients with atypical chest pain (HR: 3. 3, 95% CI: 1. 8 to 6. 0; p<0. 001), but not in asymptomatic patients (p=0. 827). However, severe CAD (≥70% stenosis) and multi- vessel CAD detected by CCTA independently predicted MACE in both asymptomatic patients (HR: 4. 7, 95% CI: 1. 4 to 15. 8 and HR: 7. 5, 95% CI: 2. 3 to 24. 4, all p < 0. 05, respectively) and patients with atypical chest pain. (HR: 11. 0, 95% CI: 6. 1 to 20. 0 and HR: 8. 2, 95% CI: 4. 3 to 15. 5, all p<0. 05, respectively). Stratifying patients by XECG and CTA fi ndings, XECG provided additional risk stratifi cation only in patients with atypical chest pain and signifi cant CAD on CCTA (n=346, 10. 0% of the total patients). Conclusions: In contrast to CCTA, XECG does not have incremental prognostic value in subjects without symptom and majority of patients with atypical chest pain. Direct assessment of coronary anatomy using CCTA might be considered in those populations.

      • SCISCIESCOPUS

        Self-Assembled Gold Nanoparticle–Mixed Metal Oxide Nanocomposites for Self-Sensitized Dye Degradation under Visible Light Irradiation

        Cho, Seungho,Jang, Ji-Wook,Hwang, Sekyu,Lee, Jae Sung,Kim, Sungjee American Chemical Society 2012 Langmuir Vol.28 No.50

        <P>Gold nanoparticle (Au NP)–mixed metal oxide (MMO) nanocomposite photocatalysts for efficient self-sensitized dye degradations under visible light were prepared by an electrostatically driven self-assembly. Dihydrolipoic acid (DHLA)-capped Au NPs (building block I) were synthesized through a room temperature reaction. Their hydrodynamic size was determined as being around 4.9 nm by dynamic light scattering measurements. MMO nanoplates with lateral dimensions of 100–250 nm (building block II) were prepared by a calcination of zinc aluminum layered double hydroxides at 750 °C for 2 h in air. In a pH 7.0 aqueous solution, the DHLA-capped Au NPs had a negative zeta potential (−22 ± 3 mV); on the other hand, the MMO nanoplates had a positive zeta potential (15 ± 2 mV). Electrostatic self-assembly was achieved by stirring an aqueous solution (pH 7.0) containing DHLA-capped Au NPs and MMO nanoplates at room temperature for 1 h. The self-assembled and sequentially calcined nanocomposites exhibited the superior self-sensitized dye degradation efficiency under visible light to that of ZnO, TiO<SUB>2</SUB> (P25), or pure MMO nanoplates. The enhanced degradation efficiency could be attributed to strong coupling interactions of ZnO and ZnAl<SUB>2</SUB>O<SUB>4</SUB> phases of the MMO and the role of Au as an electron sink and mediator for formations of reactive oxidation species and as a light concentrator.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/langd5/2012/langd5.2012.28.issue-50/la304303h/production/images/medium/la-2012-04303h_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/la304303h'>ACS Electronic Supporting Info</A></P>

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