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      • 요통환자의 외래 진료양상에 대한 조사

        조무식,김선주,원혜윤,고정관,이경석 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

        We report a series of 220 patients with low back pain who visited through neurosurgical out-patient department(OPD) from January 1994 to June 1994. We investigated how they were treated and what was the outcome on December 1995 by telephone interview. During the study period, 176 patients (80%) visited our OPD not more than twice. Frequency of OPD visit was single in 138 patients (62.7%), twice in 38 patients (17.3%), and over twice in 44 patients (20.0%). Twenty six patients (11.8%) were admitted, and 16 patients (7.3%) underwent an operation. Sixteen patients underwent surgery in this hospital, and the other 12 patients underwent surgery in any other hospitals. The rate of revisit was relatively high in patients who had a special study (58.1%), whose impression was herniated lumbar disc (41.2%) or degenerative spondylosis (55.6%), and who received prescriptions for drug (42.1%) or underwent an operation(87.5%). The rate of special study, prescriptions and/or operations of was relatively low in this hospital, which seems to lessen the rate of revisit. More active management seems to be necessary for the patient' satisfaction.

      • 차 교육 효과성 연구의 동향

        주영애,조선주 誠信女子大學校 生活文化硏究所 2009 生活文化硏究 Vol.24 No.1

        The purpose of this study is to analyze the trends in existing research on the effectiveness of tea ceremony education. This study provides basic information for future research on education programs about tea culture. Data for this study were gained from the National Assembly Library and Academic Information Center database, and they were used in content analysis. The results are as follows. First, experimental research methodology is used in most of existing research. Second, diverse variables are used to investigate the effectiveness of educational programs. Third, a variety of studies on the effectiveness of tea education are currently being conducted. Based on these results, I offer the following suggestions. An interdisciplinary research approach should be adopted in studies on the effectiveness of tea ceremony education in the future. There should be a variety of tea education programs geared toward helping people's social and emotional health. Similar to research advancement in the therapeutic effects of arts and music, further research should be developed in tea therapy.

      • Ranitidine, Sucralfate, Bismuth Subcitrate 복합제의 흰쥐 위궤양에 대한 치료효과

        조태순,조광재,주일로,이선미,유영효 成均館大學校 科學技術硏究所 1994 論文集 Vol.45 No.1

        Gastric ulcer disease results when there is an imbalance between aggressive factors(acid secretion) and protective factors(mucosal defence). H_2-receptor antagonists are the most frequently used agents for treatment of gastric ulcer disease. However, use of these products should be determined by potential for adverse effects, drug interactions and cost. Ranitidine, H_2 - receptor antagonist, competitively block the H_Z-receptor on the parietal cell, causing inhibition of gastric acid secretion. Sucralfate and bismuth subcitrate coat ulcer craters and then enhance mucosal defence. Bismuth subcitrate also causes detachment of Helicobacter pylori from the gastric epithelium with subsequent lysis of the bacteria. To estimate effects of the mixture of ranitidine 20mg/kg, bismuth subcitrate 40mg/kg and sucralfate 120mg/kg on aspirin - HCl induced gastric ulcer in rats, gastric ulceration, pH, gastric secretion, free and total acidity, pepsin activity, gastric mucosal hemorrhage were investigated. Results obtained were as follow : 1) The mixture showed remarkable suppression of gastric ulceration, pH, gastric secretion, free and total acidity, pepsin activity, gastric mucosal hemorrhage compared with ranitidine alone. 2) With elapse of time, the mixture showed more increasing inhibitory effects on gastric ulceration, pH, gastric secretion, pepsin activity, gastric mucosal hemorrhage than sucralfate and bismuth subcitrate.

      • 중·고등학교 청소년의 자살사고 및 자살시도의 유병률과 자살시도의 위험요인에 관한 연구

        조성진,전홍진,김장규,서동우,김선욱,함봉진,서동혁,정선주,조맹제 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.6

        연구목적 : 지역사회에 거주하고 있는 중·고등학교 청소년들을 대상으로 자살 사고 및 자살시도의 빈도, 성별과 연령(13∼15세 vs 16∼18세)에 따른 자살사고 및 시도의 빈도에 차이가 있는지 여부, 자살사고 및 자살시도가 있는 청소년의 특징, 그리고 자살시도의 위험요인을 알아보고자 하였다. 방 법 : 부천시에 소재하고 있는 중학교 24개교 및 고등학교 20개교의 청소년 71,102명중에서 무작위 집락 표본 추출범으로 청소년 2,203명(남자 1,105명, 여자 1,098명)을 조사대상으로 선정하였다. 자살시도 및 자살사고의 정의에 관한 항목은 Moscicki가 사용한 자살행동에 관한 4항목 중 2항목을 사용하였다. 우울증에 대한 조사도구는 the Center for Epidemiologic Studies Depression Scale, 알코올 의존에 대한 조사도구는 Composite International Diagnostic Interview의 알코올 의존 관련 항목을 사용하였다. 조사자료 통계는 빈도, 백분율, chi-square test, 단변인 및 다변인 로지스틱 회귀분석을 사용하였다. 결 과 : 본 조사연구의 분석결과를 통계적으로 유의한 차이를 보인 항목으로 살펴보면 다음과 같다. 1) 전체 대상자의 자살 사고률은 30.7%, 자살 시도률은 5.3%인 것으로 조사되었다. 남자 대상자의 자살 사고률과 시도률은 26.9%, 3.4%이었고, 여자 대상자의 자살 사고률과 시도률은 34.9%, 7.3%인 것으로 조사되었다. 성별에 따라 자살 사고률과 시도률에 통계적으로 유의한 차이가 있었다. 2) 연령(학년)을 13∼15세(중학교)와 16∼18세(고등학교)의 두 연령층으로 조사하였을 때, 중학생의 자살 사고률과 시도률은 30.1%, 4.3%이었고, 고등학생의 자살 사고률과 시도률은 31.6%, 6.4%인 것으로 조사되었다. 연령에 따른 자살 사고률에는 통계적으로 유의한 차이가 없으나 자살 시도률에는 유의한 차이가 있었다. 3) 전체 조사 대상자를 대상으로 시행한 다변인 로지스틱 회귀 분석 결과에 의하면, 자살 시도의 위험요인이 여자, 알코올 의존, 중등도 및 중증 우울 증상인 것으로 조사되었다. 남녀별로 시행한 단변인 로지스틱 회귀 분석 결과에 의하면, 남자는 알코올 의존이 있을 때, 여자는 알코올 의존, 중등도 및 중증의 우울 증상이 있을 때 자살시도의 위험성이 높았다. 결 론 : 본 연구에서 자살 사고률 및 자살 시도률이 각각 29.6%(남자 25.6%, 여자 33.7%)와 5.31%(남자 3.3%, 여자 7.3%)인 점과 자살시도의 위험요인이 우울 증상의 정도, 알코올 의존인 점을 고려할 때 알코올 의존 및 우울 증상의 조기발견과 치료, 그리고 자살 사고자 및 자살 시도자에 대한 정신의학적 접근과 추적관찰에 대한 방안이 강구되어야 할 것으로 생각된다. Objectives : Aims of this study were 1) to estimate prevalence rates of suicidal ideation and suicide attempt, 2) to find out whether the gender difference and age difference(13-15 years vs 16-18 years) for suicide behaviors exist, 3) to analyse correlates of suicide attempts among junior and high school adolescents aged 13-18 years old. Methods : A self-administered questionnaire was used in a cluster random sample of 2,203 school adolescents(male 1,105, female 1,098). Data were obtained on a wide range of constructs including suicidal ideation and attempts during past 2 weeks, depressive symptoms, symptoms of DSM-IV alcohol dependence, family structure, socioeconomic status, smoking, satisfaction with school achievements, and subjective health status. Chi-square test were done for analysing gender difference and age difference of suicide behaviors. Statistical analyses including uni-variate and multi-variate logistic regression analysis were done for each sex, respectively. Results : 1) The prevalence of suicide ideation during past 2 week was 30.7% in the total sample. The prevalence rates of male and female ideators were 26.9% and 34.9% respectively. The prevalence of suicide attempt during past 2 week was 5.3% in the total sample. The prevalence of suicide attempt in males was 3.4% and 7.3% in females. 2) Gender difference was significant. That is, female respondents showed higher rate of suicidal ideation and suicide attempt. In our study age difference was found only at the rate of suicide attempt. That is, older adolescents(16-18 years) showed only statistically significant higher rate of suicide attempt than younger adolescents(13-15 years). 3) Multi-variate logistic regression analysis revealed that the correlates for suicide attempt were female, moderate to severe depressive symptoms, alcohol dependence in the total sample. In males the correlate for suicide attempt was alcohol dependence. In females, were moderate to severe depressive symptoms, and alcohol dependence. Conclusion : Depressive symptoms, alcohol dependence, presence of suicidal ideation were strong predictors for suicide attempts. This suggest that early detection of treatment of depression and alcohol dependence is important and psychiatric approach and follow-up be needed for the prevention of suicide.

      • 순화슬러지와 생슬러지로 본 질산염제거특성

        조순자,정용주,이나은,이정은,손형식,이상준 부산대학교 환경문제연구소 2003 環境硏究報 Vol.21 No.-

        Using acclimated sludge with inorganic nitrogen medium for three months and non-acclimated sludge, raw sludge, under aerobic condition we investigated characteristics biological nitrogen removal. As results, e acclimated sludge under aerobic condition accomplished nitrification efficiently. But the samples from the reactor operated raw sludge had higher ammonium concentration rather than the concentration which was loaded by the medium. This means when we are trying to reorganize existing facilities, we should take high initial ammonium concentration into account.

      • Isoquinolinium Dichromate에 의한 Alcohol류의 산화반응 속도론과 메카니즘

        최선도,박영조,이은주 三陟大學校 産業科學技術硏究所 2003 産業科學技術硏究論文集 Vol.8 No.2

        Isoquinolinium dichromate[(C_(9)H_(7)NH)₂Cr₂O_(7)] was synthesized by the reaction of isoquinoline with chromium(VI) trioxide in water. isoquinolinium dichromate[(C_(9)H_(7)NH)₂Cr₂O_(7)] structure was verified by IR. EA and ICP. The oxidation of benzyl alcohol by isoquinolinium dichromate[(C_(9)H_(7)NH)₂Cr₂O_(7)] in carious solvents showed that the reactivity increased with the increase of the dielectric constant s order: cyclohexen < chloroform < acetone < acetonitrile. In the presence of acid, isoquinolinium dichromate [(C_(9)H_(7)NH)₂Cr₂O_(7)] oxidized the substituted benzyl alcohols in N,N-dimethylformamide. The Hammett reaction constant p was -0.69 at 303K. The observed experimental data was used to rationalize the hydride ion transfer in the rate-determining step.

      • 더덕의 효율적인 재분화 및 뿌리발달

        심주선,조숙녀,손화,김무성,노영덕,김세영,양덕춘 경희대학교식량자원개발연구소 2005 硏究論文集 Vol.24 No.-

        더덕은 식용, 관상용, 생약재료로 쓰이는 방향성 식물이다. 본 연구는, 종자의 기내배양을 통하여 식물체 재분화와 뿌리발달을 실험했다. 종자의 발아는 GA_(3) 100 mg·L(-1)처리와 저온처리 시 매우 양호하였다. 더덕의 기내에서 shoot의 형성은 2 mg·L^(-1) BA, 2 mg·L(-1) NAA가 첨가된 MS 기본배지에서 가장 양호하였으며, 줄기의 절편체와 비교하여 잎 절편체에서 재분화가 잘되었다. 또한 뿌리의 발육은 계속적인 계대배양에 의해서 양호하였는데 shoot의 길이를 1 cm 정도 남긴 뿌리를 연속적으로 4회 계대배양에서 뿌리가 주근으로 발육하였으며 길이는 약 3 cm 및 직경은 0.5 cm의 정상적인 뿌리를 얻을 수 있었다. Codonopsis lanceolata is widely used as edibles, ornamental plant and crude drug material. This study was carried out to confirm the ratio of germination and efficient differentiation of shoot and root in vitro. The germination of Codonopsis lanceolata seed was excellent in the medium with GA_(3) 100 mg·L(-1) and chilling treatment. The shoot formation of Codonopsis lanceolata was good at the MS medium with 2 mg·L(-1) BA and 2 mg·L(-1) NAA. According to inoculum part, ratio of re-differentiation was higher from the leaf explant compared with the stem explant. For root development, successive subculture with 1 cm shoot of upper part from root was efficient. Roots of Codonopsis lanceolata cultured in vitro system was grown like normal root with length of 3 cm and thickness of 0.5 cm at the 4 successive subcultures.

      • KCI등재
      • Isoquinolinium Chlorochromate와 Quinolinium Chlorochromate를 이용한 알코올류의 선택적 산화반응

        최선도,박영조,이은주 三陟大學校 産業科學技術硏究所 2003 産業科學技術硏究論文集 Vol.8 No.2

        Isoquinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) and quinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) were synthesized. which were used to oxidize benzylic alcohol, allylic alcohol. primary alcohol and secondary alcohols in DMF to give aldehyde of each compound. Their structures were verified by IR, EA and ICP. The oxidation of alcohols was examined by isoquinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) and quinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) in DMF. As a result, isoquinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) and quinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) were found as efficicent oxidizing agents that converted benzylic alcohol, allylic alcohol, primary alcohol and secondary alcohols to the corresponding aldehydes or ketones. The selective oxidation of alcohols was also examined by isoquinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) and quinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) in DMF. isoquinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) and quinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) were selective oxidizing agents of benzylic alcohol. allylic alcohol and primary alcohol in the presence of secondary alcohols.

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