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스포츠 과학 분야에서는 운동 선수들의 경기력 향상과 운동 피로의 신속한 회복을 도모하기 위하여 한약을 복용하고 그 효과와 유의성에 대하여 연구가 활발히 이루어지고 있다. 격심한 운동을 수행할 때 나타나는 Glucose 등 에너지원의 고갈, Lactate 등 대사 산물의 축적, 전해질의 불균형 등의 여러 제반 증상이 氣虛로 인하여 나타나는 전신의 증후와 유사하다고 생각하여 補中益氣湯을 투여한 후 인체의 대사 변화를 관찰함으로서 운동수행능력에 미치는 영향과 유의성을 평가하고자 하였다. 본 연구는 장거리 달리기 선수를 대상으로 2주간의 補中益氣湯의 투여가 에너지 대사 및 전해질대사에 미치는 영향을 규명하기 위하여 최대심박수의 70% 강도의 운동을 실시한 후 운동전 안정시, 운동 직후, 휴식 후 10분, 휴식 후 30분, 휴식 후 1시간으로 나누어 혈액검사를 하였을 때 나타나는 각종 변인의 반응 양상을 비교 분석하여 유의한 결과를 얻었다. 혈중 에너지 대사에서는 free fatty acid와 Lactate 반응에서 유의성 있는 차이가 나타났고, 전해질대사에서도 Na^(+), Cl-와 K^(+) 반응에서 모누 유의성 있는 차이를 나타냈다. 그러므로 補中益氣湯은 에너지 및 전해질 대사에서 유의성있는 변화를 나타내었으며 운동수행능력의 향상에 유효하였다. Objective This experimental study was designed to investigate effects of Bo-joong-ik-gi-tang administration among long distance runners on changes of the energy and electrolyte metabolism. Materials and Methods All subjects were divided randomly with two groups, Bo-joong-ik-gi-tang Group (N=4) and control group (N=4) and performed to run the 400m track with 70% of HR max about 1 hour. The blood samples were collected from antecubital vein by 5㎖ syringes at before exercise, immediateIy after exercise, recovering- 10 min, recovering-30 min, recovering-1 hour. These sampie were used to analyze for the factors of the changes on metabolic responses. Firest, the primary factors on the changes of the energy metabolism were checked ; Glucose, Free fatty acid, Lactate, LDH. Second, the primary factors on the changes of the electroIyte metabolisrn were checked ; Na^(+), Cl^(-), K^(+). Results 1. The change of the energy metabolism 1) Glucose response was not shown significant difference between two groups. 2) Free fatty acid response in Bo-joong-ik-gi-tang group was significantly increased at recover-10 min. 3) Lactate response in Bo-joong-ik-gi-tang group was significantly decreased at immediately after exercise, recover-10 min, recover-30 min. 4) LDH response was not shown significant difference between two groups. 2. The change of the electrolyte metabolism 1) Na^(+) response in Bo-joong-ik-gi-tang group was shown significant difference between two groups at before exercise. 2) C^(-) response in Bo-joong-ik-gi-tang group was significantly increased at before exercise, immediately after exercise. 3) K^(+) response in Bo-joong-ik-gi-tang group was significantly increased at recover-10 min. Conclusion According to the above results, it was shown that Bo-joong-ik-gi-tang had the positive effects on changes of the energy and electrolyte metabolism for the long distance runners.
( Dam Kim ), ( Soo-kyung Cho ), ( Seoung Wan Nam ), ( Hyuk Hee Kwon ), ( Sun-young Jung ), ( Chan Hong Jeon ), ( Seul Gi Im ), ( Dalho Kim ), ( Eun Jin Jang ), ( Yoon-kyoung Sung ) 대한류마티스학회 2017 대한류마티스학회지 Vol.24 No.5
Objective. To estimate the cardiovascular (CV) and gastrointestinal (GI) risks of etoricoxib in the treatment of osteoarthritis (OA) compared to a placebo and other non-steroidal anti-inflammatory drugs (NSAIDs). Methods. A systematic review of randomized, controlled trials (RCTs) of etoricoxib were performed. Bayesian network meta-analysis was used over a duration of 12 weeks. The incidence of CV and GI events for a duration ≥26 weeks were also tabulated and presented using descriptive statistics. Results. From this search, 10 studies were identified. Of these, 6 and 5 RCTs that measured the CV and GI events at 12 weeks were included in meta-analysis. They showed that etoricoxib did not increase the CV events compared to the placebo or NSAIDs during the 12 week period (odds ratio [OR]=0.59 compared to celecoxib, OR=0.89 with ibuprofen, OR=0.70 with placebo, and OR=2.16 with naproxen). The risk of GI events was comparable to that of most comparators, with the exception of naproxen, which had a significantly lower risk of GI events (OR=0.18) during the 12 week period. For a duration ≥26 weeks, the incidence of CV and GI events with etoricoxib increased with increasing duration. Conclusion. Etoricoxib is an alternative short-term treatment option for OA, showing comparable CV and GI complications to other NSAIDs. Nevertheless, further studies will be needed to elucidate the long-term safety of etoricoxib in the treatment of OA. (J Rheum Dis 2017;24:293-302)
Zemike moments have been one of the most commonly used feature vectors for recognizing rotated patterns due to its rotation invariant characteristics. In order to reduce its expensive computational cost, several methods have been proposed to lower the complexity. One of the methods proposed by Mukundan and K. R. Ramakrishnan , however, is not rotation invariant. In this paper, we propose another method that not only reduces the computational cost but preserves the rotation invariant characteristics. In the experiment, we compare our method with others, in terms of computing time and the accuracy of moment feature at different rotational angle of an object in image.
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Objective: Children with spastic diplegic cerebral palsy show weakness especially in the lower-ex-tremity rather than upper-extremity muscles and display characteristics such as asymmetric alignment, deficits in postural control or balance ability, and slow walking speed. Various therapeutic interventions are applied to children with cerebral palsy, of which taping is widely used in the field of rehabilitation, however, there are few studies of the effects of kinesio taping on gait patterns of children with cerebral palsy. The present study investigated the effects of kinesio taping on gait parameters of children with cerebral palsy. Design: Cross-sectional study. Methods: Four children with spastic diplegia participated in this study. The participants` gait parameters while walking 10 m with and without kinesio taping (tibialis anterior, quadriceps femoris, and gluteus maximus) were recorded. Gait parameters including gait velocity, cadence, step length, stride length, single support time, and double support time were evaluated using the GAITRite. Mean values were obtained after having the subjects walk three times in each condition with a 5-minute rest period between each condition. The order of each condition was assigned randomly. Results: There were significant improvements in gait velocity, step length, stride length, and single support time of the right leg with kinesio taping condition compared to the without kinesio taping condition taping (p<0.05). However, there were no significant differences in cadence, single support time of the left leg, or double support time. Conclusions: The results show that kinesio taping may have a positive effect for improving gait parameters of children with spastic diplegia. However, its usefulness in the rehabilitation of children with cerebral palsy needs to be further investigated.
Sun Nyoung(유선녕), Jeong Bin Ahn(안정빈), EunYoung Park(박은영), Sun Jung Lee(이선정), Min Gi Tak(탁민지), Kwang Youn Kim(김광연), Sang Hun Kim(김상헌), Ki Dae Kim(김기대), Soon Cheol Ahn(안순철) 한국생명과학회 2012 생명과학회지 Vol.22 No.8
본 연구에서는 각기 다른 형태의 지방산이 ICR mice의 혈중 지질 농도에 미치는 영향을 평가하고자 하였다. 이를 위하여 8주령 수컷 ICR mice를 일반 식이섭취군(C), 10%의 트랜스 불포화 지방산 섭취군(TFA-1), 30% 트랜스 불포화 지방산 섭취군(TFA-2), 50% 트랜스 불포화 지방산 섭취군(TFA-3), 50% 포화 지방산 섭취군(SFA), 불포화 지방산 섭취군(USFA) 으로 나누어 식이 하였다. 혈중 총 콜레스테롤의 수치는 TFA-3 군과 SFA 군의 지질함량이 다른 군에 비하여 높았으며, 중성지방지수 역시 높게 나타났다. 총 콜레스테롤과 중성지방수치를 이용하여 나타낸 LDL 콜레스테롤의 경우에도 50%의 트랜스 지방산을 섭취한 군에서 포화 지방산을 섭취한 군과 유사한 결과가 나타났다. 이에 반해, 10%, 30%의 트랜스 지방산을 섭취한 군에서는 일반식이 섭취군과 비슷한 결과가 나타났다. 이는 많은 양의 트랜스 불포화지방산을 짧은 기간 동안 섭취하더라도 포화지방산을 섭취한 것과 유사한 효과를 나타낸다는 것을 의미한다. The purpose of this study was to investigate the effects of trans-unsaturated fatty acid (TFA), saturated fatty acid (SFA) and general unsaturated fatty acid (USFA) on serum lipid levels in ICR mice. Male ICR 8-week-old mice were divided into six groups; the control group (C) fed with normal diet, the TFA-1 group fed with 10% trans-unsaturated fatty acid, the TFA-2 group fed with 30% trans-unsaturated fatty acid, the TFA-3 group fed with 50% trans-unsaturated fatty acid, the SFA group fed with 50% saturated fatty acid, and USFA group fed with 50% general unsaturated fatty acid. The serum total cholesterol of TFA-3 and SFA was higher than those of other fat groups and C. The serum triglyceride (TG) of TFA-3 and SFA showed the highest levels among all of diet groups. Also the serum HDL cholesterol levels of TFA-3 showed the lowest. LDL cholesterol and atherogenic indices (AI) were remarkedly increased in TFA-3 and SFA, as compared with other fat fed groups and C. Taken together with results, the TFA-3 group showed serum lipid levels similar to the SFA and different from the USFA. These results suggest that intake of high level of trans-unsaturated fatty acid increased serum triglyceride, LDL cholesterol and atherogenic indices, which may affect risk on serum lipid level for lipid metabolism syndrome.
Among the diverse crops, rice (Oryza sativa L.) has been domesticated as a staple carbohydrate sources mainly in Asia region, and RDA Genebank at the National Agrobiodiversity Center (NAAS) has conserved about 37 thousand rice accessions accordingly. Seed dormancy, one of domesticated traits, prevents pre-harvest sprouting (PHS) which causes degradation of grain quality in cereal crop. In previous study, we surveyed the variation of seed germinability of diverse 200 rice germplasm and detected the three distinguished groups besides admixed types; the first group (G-1) revealed high germinability at harvesting time, and the second group (G-2) and third group (G-3) acquired high germnability subsequent to after-ripening and dormancy breaking process, respectively. To reduce environmental effects on detected variation of germinability, we selected representative 14 accessions which have similar heading date of each group and measured the degree of PHS using freshly harvested panicles. Variation of PHS showed similar tendency of germinability group; generally, high PHS for G-1, low PHS for G-2 and no PHS for G-3. To resolve genetic and physiological factors concerning on PHS and seed dormancy, we checked the change and variation of ABA known for critical regulator for seed dormancy, and high PHS accessions interestingly revealed high ABA content in 10 DAF. Based on these study, we plan to analyze genetic factors affecting the degree of seed germinability and PHS.