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      • KCI등재후보

        Starter 및 멸치액젓 첨가가 김치양념 및 겉절이 김치의 품질에 미치는 영향

        최택권,박소희,유진현,임호수,조재선,황성연 한국식생활문화학회 2003 韓國食生活文化學會誌 Vol.18 No.2

        양념에 Leu. mesenteroides, Lac plantarum의 젖산균과 멸치액젓 첨가가 김치 양념의 대장균군 제어, 속성촉진여부 및 관능적 특성에 미치는 영향을 조사하였다. Leu. mesenteroides과 젓갈을 첨가한 경우 초기 숙성이 촉진되나 후기 산패는 완만하였으며 Lac. plantarum의 첨가시에는 초기 숙성에는 큰 차이가 없고 후기 산패가 현저하게 진행되었다. 대장균군은 산도 0.80% 이상에서 사멸되었는데 leu. mesenteroides의 경우가 숙성이 촉진되어 보다 신속히 사멸시켰다. 총균수와 젖산균수는 초기에 starter 첨가구는 10^6CFU/mL 정도인데 반해서 starter를 첨가하지 않은 않은 처리구에서 총균수는 10^6CFU/mL , 젖산균수가 10^4CFU/mL 이었고 숙성 후에는 첨가균이 높은 수준을 유지하였다. 하지만 대체적으로 스타터의 첨가가 숙성 및 대장균에 크게 영향을 주지 못하는 경향으로 동일하게 나왔다. 관능적 특성에서는 Leu. mesenteroides 첨가구가 Lac. plantarum의 경우보다 우수하였다. 한편, 시판 겉절이 김치는 산도가 0.09~0.18%, ph 5.46~5.89, 총균수 2.2×10^6~3.1×10^7CFU/mL, 젖산균수는 2.1×10^4~6.6×10^5CFU/mL, 대장균수는 1.8×10^4~7.1×10^5CFU/mL, 염분 1.89%~2.51%으로 스타터 첨가 겉절이에 비해 ph와 염도를 제외한 품질 특성에서 전반적으로 낮은 값을 나타냈다. This study was performed in order to investigate the effect of Leuconostoc mesenteroides, Lactobacillus plantarum and salt fermented anchovy extracts on Kimchi sauce. The sauce was fermented more rapidly by addition of Leu. mesenteroids or salt fermented anchovy extracts on the early fermentation stage than the control, but it was fermented slowly on the late fermentation stage. When L. plantarum was added to the Kimchi on the early fermentation stage, the acidity of Kimchi didn't show a significant difference from the control, but acidity was remarkably increased on the late stage. Coliform group was disappeared when acidity of sauce was higher than 0.8% during fermentation. It was controlled by Leu. mesenteroides but not by L. plantarum. Total count and lactic acid bacterial count of the sauces with starter were 6.30×10^6~1.0×10^7 CFU/mL and 1.04~2.04×10^6 CFU/mL, respectively, but those of the control sauce were 10^6 CFU/mL and 10^4 CFU/mL, respectively. Those count of the sauce with starter were higher than those of the control sauce on the later stage of fermentation. Organoleptic quality of the sauce with Leu. mesenteroides was superior to that with L. plantarum.

      • KCI등재

        다래나무 및 노각나무 수액의 성분조성

        최선영,나성택,김용환,김행자,성낙주 경상대학교 농업생명과학연구원 2002 농업생명과학연구 Vol.36 No.2

        본 실험에서는 다래나무 및 노각나무 수액을 천연 건강음료로 개발하기 위한 기초 자료를 얻고져 물리ㆍ화학적 성질과 유리당, 무기물 및 구성 아미노산 등을 분석하였다. 다래나무와 노각나무 수액의 pH, 비중, 당도, 수분, 회분 및 조단백질의 함량은 거의 비슷하였다. 유리당 함량은 fructose가 다래나무 수액에서 378.4㎎/100㎖, glucose는 노각나무 수액에서 125.4㎎/100㎖로 가장 높은 함량이었다. 무기물 조성은 망간과 알루미늄을 제외한 모든 무기물에서 노각나무 수액에 비해 다래나무 수액에서 함량이 높았으며 특히 칼슘은 다래나무 수액이 172.0㎎/ℓ, 노각나무 수액에서 13.7㎎/ℓ로 다래나무 수액이 노각나무 수액보다 약 13배나 높은 함량을 보였다. 다래나무 및 노각나무 수액은 분석된 총 17종의 구성 아미노산 중 다래나무 수액은 4종, 노각나무 수액에서는 6종이 검출되었는데, 다래나무 수액은 cystine, aspartic acid, serine 그리고 valine의 순으로 노각나무 수액에서는 cystine, glutamic acid, aspartic acid, serine, valine 및 phenylalanine 등의 순으로 함량이 높게 나타났다. Natural compounds such as free sugars, minerals and composition amino acids in Darae(Actinidia arguta) and Korean stewartia(Stewartia koreana) saps were analyzed to establish to the basic data of foods. Free sugars of the saps determined were fructose and glucose which were detected higher amounts as 378.4 and 125.4㎎/100㎖, respectively, but sucrose and maltose were not detected. Among 10 kinds of mineral detected in the saps, the content of calcium in Darae and aluminum in the Korean stewartia saps was the highest 172.0 and 56.1㎎/ℓ, respectively. The calcium content in Darae saps was 13 times higher than that of Korean stewartia saps. The Darae saps were composed of 4 kinds of amino acids such as cystine, aspartic acid, serine and valine, and then Korean stewartia saps 6 kinds of amino acids such as cystine, glutamic acid, aspartic acid, serine, valine and phenylalanine. It is concluded that saps of Darae and Korean stewartia contain a good variety of natural compounds such as free sugars, minerals and amino acids to serve as an excellent source of very natural and health promoting drinks.

      • 담즙정체성 간염의 임상적 양상

        최선택,은종렬,임상우,김봉준,이헌주,구미진,최준혁 영남대학교 기초/임상의학연구소 2001 Yeungnam University Journal of Medicine Vol.18 No.1

        Background: Cholestatic hepatitis is failure of bile to reach the duodenum with hepatocellular damage and no demonstrable obstruction of the major bile ducts. The prognosis is usually good with recovery in less than 4 weeks after withdrawal of the offending drug. However, a prolonged course lasting over 3 months is possible and, in rare cases, progression to ductopenia with development of a vanishing bile duct syndrome occurs. A differential diagnosis with other causes of Chronic liver disease is needed. Materials and Methods: From January 1991 through Jaunary 2000, 14 patients diagnosed as cholestatic hepatitis by liver biopsy were inclouded. The possible causative drug, clinical features, laboatory findings, and progression of cholestatic hepatitis were evaluated. The semiquantitative study of liver lesions was performed by two independent observers. Results: Causes of cholestatic hepatitis are 5 cases of oriental medicine, 3 cases of anti-tuberculosis medication, 1 case of ticlopidine and antibiotics and 4 cases of unknown causes. The clinical features of cholestatic hepatitis were jaundice, itching, urine color change, and general weakness. During 6 to 30 months, LFT of 5 patients showed prolonged elevation. Elevated total cholesterol ≥250 mg/dL in 6 patients, pheripheral blood eosinophilia in 5 patients, auto-antibody positive in 6 patients were observed respectively. The biopsies showed intralobular bilirubinostasis with a mixed portal inflammatory infiltration. Conclusion: In cholestatic hepatitis. durations of abnormal LFT are variable regardless of causative drugs. If cholestatic hepatitis progresses toward chronic course, viral hepatitis, primary biliary cirrhosis, and autoimmune hepatitis should be differentially diagnosed and sequential liver biopsies are needed.

      • KCI등재

        유색미에 관한 연구 : Ⅲ. 유색미 유망계통에 대한 주요 생육 특성

        김광수,최윤표,김선택,최현구,정종태,김보경,유지홍,이희봉 충남대학교 농업과학연구소 2007 농업과학연구 Vol.34 No.2

        국내외 유색미 수집종을 돌연변이원에 의해 유기된 우수 계통과 수집종간 상호교배에 의해 선발된 CNU 20계통을 파종하여 얻어진 주요 작물학적 특성을 살펴보면 다음과 같다. 1. 간장은 유색 메벼인 CNU126 계통이 대조품종인 동진벼와 같이 가장 컸고 메성인 CNU 128계통에서 가장 작았다. 2. 주당 분얼수는 CNU3, CNU50. CNU56, CNU112 계통에서 가장 많았고 대조품종과 CNU 128 계통에서 10개 미만으로 가장 적게 나타났다. 3. 수장은 육성 계통 중 CNU88 계통에서 가장 길었으나 대조구보다 짧고, 육성계통 중에서는 CNU 126 계통이 가장 짧았다. 4. 주당 영화수는 대조구인 동진벼보다 CNU50 계통에서 2배 이상 많았고, CNU158 계통에서 가장 적게 나타났다. 5. 천립중은 CNU113 계통에서 30g이상으로 대조구와 같이 가장 무거웠고, CNU128 계통에서 20g으로 가장 적었다. 6. 주당 수량은 대조구의 26.6g에 비해 CNU50, CNU112 계통에서 두배정도 높았고, CNU128, CNU158, CNU200 계통에서 가장 낮게 타나났다. Aims of this study were carried out to develop the useful lines induced from mutation and pedigree breeding methods among the collected genetic resources from national and domestic areas. In this study, Stem height of CNU126 line and check among them were high, while CNU128 was lower than other lines. Spiklet length of CNU88 was longer, but that of CNU126 was shorter than check. Number of spiklets per plant of CNU50 among lines have twice time than check. 1,000 grains weight of CNU113 was higher than check. In yield per plant, CNU50 and CNU112 were higher than check, Dongjinbyeo.

      • 제지폐수처리용 생물고분자응집제를 생산하는 Bacillus sp. K-111의 배양특성조사

        권기석,손용호,최선택,정석관,송숙희,김동걸 7개 국립대학교 환경연구 논문집 공동발행 위원회 2002 환경연구논문집 Vol.2 No.1

        Flocculant-producing microorganisms were screened from obtained strains in the laboratory using a pulp-wastewater treatment as the flocculating agent. K-111 strain that had high flocculating activity among them was selected and identified as Bacillus sp. K-111 16s rDNA sequencing. The favorable medium for the production of flocculant was glucose 1.5%, NH_4NO_3 0.2%, tryptone 0.01%, K_2HPO_4 0.08%, KH_2PO_4 0.06%, CaCO_3 0.03%, MgSO_4·7H_2O 0.005%, MnSO_4 0.005% in 1 liter of D.W. at initial pH 7.0. The optimum culture temperature and pH were 30℃ and pH 7.0, respectively. the flocculating activity was observed most highly after 36 to 48 hr of cultivation at the optimum conditions. the flocculating activity of produced biopolymer on optimum conditions was about 2.5-fold higher than that of screening medium.

      • KCI등재후보

        Bromocriptine 과 Cyproheptadine 이 Corticotropin-releasing Factor(CRF) 로 자극된 ACTH 분비에 미치는 효과

        김진우,최영길,김영설,김광원,김선우,양인명,윤현구,우정택 대한내과학회 1986 대한내과학회지 Vol.31 No.5

        Our study was desinged to observe the ACTH response to ovine CRF in healthy men and to observe the effect of bromocriptine or cyproheptine on ACTH and cortisol response induced by ovine CRF in healthy men. We have hypothesis that if hromocriptine or cyproheptatine inhibits the secretion of ACTH induced by ovine CRF, they decrease the secretion of ACTH in the pituitary level. The result were followings: 1) Plasma ACTH reached a peak of 1.5 and 1.6 times the basal level in response to ovine CRF at 10 min, and 30 min, respectively and decreased to the basal level at 90 min. 2) Cyproheptadine or bromocriptine did not inhibit the response of ACTH to ovine CRF. 3) We suggest that cyproheptadine or bromocriptine does not inhibit the ACTH secretion in the normal pituitary gland.

      • SCOPUSKCI등재

        Pulmonary Langerhans Cell Histiocytosis in an Adult Male Presenting with Central Diabetes Insipidus and Diabetes Mellitus: A Case Report

        Choi, Yeun Seoung,Lim, Jung Soo,Kwon, Woocheol,Jung, Soon-Hee,Park, Il Hwan,Lee, Myoung Kyu,Lee, Won Yeon,Yong, Suk Joong,Lee, Seok Jeong,Jung, Ye-Ryung,Choi, Jiwon,Choi, Ji Sun,Jeong, Joon Taek,Yoo, The Korean Academy of Tuberculosis and Respiratory 2015 Tuberculosis and Respiratory Diseases Vol.78 No.4

        Pulmonary Langerhans cell histiocytosis is an uncommon diffuse cystic lung disease in adults. In rare cases, it can involve extrapulmonary organs and lead to endocrine abnormalities such as central diabetes insipidus. A 42-year-old man presented with polyphagia and polydipsia, as well as a dry cough and dyspnea on exertion. Magnetic resonance imaging of the hypothalamic-pituitary system failed to show the posterior pituitary, which is a typical finding in patients with central diabetes insipidus. This condition was confirmed by a water deprivation test, and the patient was also found to have type 2 diabetes mellitus. Computed tomographic scanning of the lungs revealed multiple, irregularly shaped cystic lesions and small nodules bilaterally, with sparing of the costophrenic angles. Lung biopsy through video-assisted thoracoscopic surgery revealed pulmonary Langerhans cell histiocytosis. On a follow-up visit, only 1 year after the patient had quit smoking, clinical and radiological improvement was significant. Here, we report an uncommon case of pulmonary Langerhans cell histiocytosis that simultaneously presented with diabetes insipidus and diabetes mellitus.

      • Clinical characteristics of post-operative N2 nodal upstaging in Non-small cell lung cancer

        ( Sun Young Choi ),( Sung Yoon Lim ),( Choon-taek Lee ),( Jae Ho Lee ),( Ho Il Yoon ),( Young-jae Cho ),( Jong Sun Park ),( Yeon Joo Lee ),( Eun Sun Kim ),( Byung Soo Kwon ),( Yung Hee Lee ),( Yeon Wo 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-

        Background: Endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) is currently performed first for the mediastinal nodal staging of non-small lung cancer (NSCLC). However, unsuspected lymph node metastases leading to upstaging are found during the final histopathologic evaluation of surgical specimens. Purpose of our study was to evaluate the characteristics of upstaged lymph nodes and the its effects on survival in patients with NSCLC. Methods: We performed a retrospective review from 2009 to 2019 at tertiary-care academic hospital. Patients who diagnosed NSCLC with post-operative pathologic N2 positive lymph node were included. Nodal upstaging was defined as the unexpected pathological finding of metastasis in N2 nodes in patients who were presumed to have clinical N0 or N1 with preoperative staging. Results: Of 177 patients with positive N2 node postoperatively, overall rate of nodal upstaging was 53.1% (94 patients). The baseline characteristics did not differ significantly between upstaged and unchanged patients. Upstaged patients were more likely to receive adjuvant chemotherapy compared to unchanged patients. Culprit nodes leading to upstaging were subcarinal (38.3%), paratracheal (36.2%), and aortic nodes (21.3%). The size of upstaged node was less than 5mm in EBUS. Threeyear mortality was not different between two groups, but lower rate of mortality was observed after excluding inaccessible lymph node. Progression-free survival was significantly higher in the upstaged patients. Conclusion: Nodal upstaging was mainly attributed to the small mediastinal nodes or aortic nodes that are not accessible by EBUS-TBNA and did not influence three-year mortality. After excluding inaccessible lymph node, even higher survival was found in the upstaged patients than the unchanged patients with the same stage.

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