정신분열병에 대한 Risperidone의 효과 및 안전성에 관하여

신석철,왕성근,지익성,이선우,이규광,이봉희,이진영,황선희,신용재,배경도,김정란 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

In order to evaluate the efficacy and safety of risperidone, 10 patients with chronic schizophrenia were examined for 8 weeks in a silgle-open study. After the wash-out period of 1 week, risperidone was administered. Efficacy was evaluated by means of Positive and Negative syndrome Scale for Schizophernia(PANSS) and Clinical Global Impression(CGI). Safety assessment included the Extrapyramidal Symptom Rating Scale(ESRS), vital signs, body weight, ECG, and laboratory tests. The results were as follows 1) On the PANSS total score, there was significant improvement of total score after 1 week (P<.05) of administratiom. 2) On the PANSS positive and negative subscal, there were significant improvement of posotive and negative scores after 2 weeks (P<.05) of administration. 3) On the PANSS general psychopatholgy subscals, there were significant improvement of general psychopathologyscores after 1 week (P<.05) of administratiom. 4) On the CGI, there was significant decreasement of clinical impression of severity of schizophrenia score after 2 week (P<.05) of administration. 5) A statistically significant increase in body weight (P<.05) was observed after 8 weeks of administration. 6) EPS reached the peak at the end of the 1st week of administration of risperidone (11.8± 24.25) but they were easily relieved by addition of benztropine and clonazepam. There was not significant change in laboratory tests, vital sign, ECG after 8 weeks of administration. These results suggest that Risperidone is an effective antipsychotics and clinically safe except for increased body weight in chronic schizophrenia.

역할놀이 프로그램이 방과후 아동의 친사회적 행동 변화에 미치는 영향

신선희 한국아동교육학회 2003 아동교육 Vol.12 No.2

The purpose of this study was to examine the effect of a role-play-training program on children's prosocial behaviors after school. The program consisted of emotional controlling skills of individual, personal techniques to make and maintain social relationship, and individual adaptability to school life and so on. To do this research, extracurricular activities of the role-play program was introduced to 20 first and second traders after school. Mixed design was used for gathering the data, which was analyzied by ANCOVA. The results were as follows: 1. The program improved the emotional controlling skills of an individual. 2. The program improved personal ability to make and maintain social relationships with peers. 3. The program was beneficial for children's adaptability to school life. In sum, this study showed that prosocial training program has developed children's prosocial behaviros such as making and maintaining social relationships with others. Therefore, a role play program with extracurricular activities has a significant impact on changing children's prosocial behavior patterns during their social life.

아동의 건강 및 질병개념 발달에 관한 탐색적 연구

신희선 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.1

This study examined the development of children's concepts of health and illness based on Piaget's cognitive developmental theory of children. Conceptions of health and illness of 72 children aged 3 to 12 were explored by interview, using interview guide developed by Bibace and Walsh. Six developmentally ordered categories of explanation of illness were utilized for data analysis. The results were as follows: The types of explanation of illness varied as a function of the developmental status of the subjects. Among preschool chidren, 79.2% gave the prelogical explanations including phenomenism and contagion. Among 7 year olds, 45.8% gave contamination explanations and 29.2% internalization explanations. Among 11 to 12 year olds explanations were classified as 58.3% internalization and 12.5% physiologic. The answers to the question "What does it mean to be healthy?" showed qualitative and quantitative changes with age. Among preschool children, "Strong body"(20.8%) and "Eating well"(12.5%)were the mostly mentioned categories. Among 7 year olds, "Not being sick" (41.7%) and "Strong body"(37.5%) were the mostly mentioned categories. Among 11 to 12 year olds, "Strong body" (41,7%) and "not being sick" (33.3%) were the mostly mentioned categories And, mental health was considered a part of health by 16.7 % of this age group children. When children were asked about specific illnesses, knowledge varied with the illness, Children were knowledgeable about headache and heart attack but knew little about cancer and measles.

서울시 교직원의 고혈압 실태파악과 그 요인에 관한 연구

신선미,김종희,한규종,이희우 韓國學校保健學會 2004 韓國學校保健學會誌 Vol.17 No.1

Purpose : To describe epidemiological characteristics and related factors in school personnel with hypertension. Method : 5,384 school personnel (2,638 males and 2,746 females) received physical examination at the Seoul School Health Center in 2002. blood pressure(BP) was classified by JNC 7th report. Normal BP is systolic BP <120 and diastolic BP<80, prehypertension BP is 120-139 or 80-89mmHg, stage 1 hypertension BP is 140-159 or 90-99, and stage 2 hypertension >=160 or >=l00 mmHg. each group was evaluated by gender. We used multiple regression and logistic regression. Results : Normotension was 20.13% in d e s and 48.65% in female, prehypertension 43.4% in males and 3.06% in females, stage 1 hypertension 26.38% in males and 10.99% in females, stage2 hypertension 9.59% in males and 3.2% in females. the older age group had higher distribution of stage 1 hypertension and stage 2 hypertension. The means and abnormal rates of BMI, blood sugar, total cholesterol, GOT, GPT, and GTP was higher when their blood pressure was higher. However, an alcohol habit among lifestyle factors had an inverse effect. Higher Bp was correlated to a &her BMI, FBS, and cholesterol-like dose response. In stage 1 hypertension, the related factors of hypertension for males were BMI, amount of cigarettes smoked, exercise, blood sugar, total cholesterol, and GTP. In stage 1 hypertension, age, BMI, exercise, blood sugar, total cholesterol were related factors in female. In stage 2 hypertension, age and smoking were related factors in male, and age, BMI, and cholesterol in female. Conclusions : It is possible to intervene in all related factors of hypertension except age through life-style modification and appropriate medical management. Active health promotion is needed in School personnel.

韓國産 개불(Urechis unicinctus) 前腸 上皮細胞 纖毛의 構造와 機能에 대하여

신길상,이순희 순천향대학교 기초과학연구소 1997 순천향자연과학연구 논문집 Vol.3 No.1

Urechis unicinctus is one of many tide animals known as a filter feeder. With filter, the animal effectively select plankton and debris from influxed sea warter into the fore gut. The filtering mechanism of this animal is yet not well understood, although ciliary movement of proboscis is in common filtering mechanism in some tide and water invertebrates. In this study with U. unicinctus it is revealed unusally that the filter is not in proboscis, but it is a part of unbranched hollow visceral organ which extend from proboscis to anal portion. The structural observation enable to analyze the filtering mechanism represented by ciliary movement in the fore gut. This results come from the structural considerations led to a possibility that the visceral organ is functionally compartmented into 3 parts, mid gut, hind gut and the fore gut. The hind gut as a respiratory organ and the mid gut as a digestive organ are already known but the 3 compartments consist exclusively with the fore gut as the filter in its function. The fore gut composed of pseudostrafied columnar epithelial cell with the cilia. The internal cilia are well differentiated kinocilia with the typical microtubule pattern, kinetosome and cilia roots. There are two kinds of striated cilia roots, main root extending perpendicularly from cell surface to basement membrane and short accessory root branching with an acute angle of 80°with the main root at basal plate of the kinetosome. The spacial approach of the main root to the large fused form of mitochondria is one of characteristic features which might be a intimate association between energy source and energy mass consuming cell organelles.

좌측 관동맥에서 시작된 관동정맥루에 동반된 거대 동맥류 1예

신미승,맹선희,이혜진,조홍근,정의모,신길자 대한순환기학회 1999 Korean Circulation Journal Vol.29 No.7

우태아혈청 및 성인뇨중 β-에스트라디올, 에스트론, 에스트리올의 역상 HPLC

신희수,이동선 서울여자대학교 자연과학연구소 1997 자연과학연구논문집 Vol.8 No.-

A method for reversed phase high performance liquid chromatographic separation of estriol, estradiol, and estrone in biological samples such as human urine, fetal bovine serum is described. Estrogens were determined by HPLC following solid phase extraction using Sepak C18 cartridge for sample clean up. Chromatographic separation is completed in 10 min using mobile phase of 60v/v% acetonitrile in water and Spheri-5 RP-18 column (4.6mm*22cm, 5micron) at flowarte of 0.5ml/min. UV-detection of eluted compounds was accomplshed at 280nm. Retention time of triol was shorter than those of diol and monool. These result suggests than triol is polar than diol and monool.

농촌지역 중학생의 학용품 구매 행동에 관한 연구

신순덕,안영희,경상대학교 가정교육과 한국 가정과 교육 학회 1997 한국가정과교육학회지 Vol.9 No.1

The purpose of this study is to understand middle school students' behavior of purchasing school things at rural area and to provide basic data which is necessary for consumer education to help them with more reasonable purchasing behavior. The results of this study were as follows : 1) The level of purchasing behavior for the school things of middle school students at rural area is 3.15 out of perfect Score 5, and shows medium level. Middle school students' behaivor of purchasing school things at rural area showed significant difference in social demographic variables such as sex, grade and keeping a record money spending. 2) 75.5% of middle school students' consuming experiences was shown to be on a midium. According to the results of this study, it was showed the more consuming experience they had, the more reasonable purchasing behavior they did. There was significant positive correlation between consuming experiences and behavior of purchasing school things. 3) Middle school students at rural area were highly realizing the necessity for consuming education both at home(91%) and at school(93.9%). Also, there was a significant positive correlation between the necessity for consumer education and behavior of purchasing school things.

S Leadership 함양을 위한 숙명여대 의사소통센터의 교양교육 사례연구

신희선 숙명여자대학교숙명리더십개발원 2007 숙명리더십연구 Vol.6 No.-

숙명여대는 리더십 교양교육을 강화하면서 의사소통능력이 탁월한 여성 리더를 육성하고자 교양필수과정으로 <글쓰기와 읽기>, <발표와 토론> 강의를 개설하였다. 학제적이고 통합적인 리더십 교양교육의 차원에서 의사소통센터를 제도화하여 신입생들을 대상으로 사고와 표현능력을 키우는 교육을 실시하고 있다. 이는 아카데미즘에 충실한 대학 교육 본연의 자세를 견지한 기초교육이면서, 동시에 현대사회가 요구하는 실용적인 맞춤형 인재를 양성하기 위한 목적을 내포하고 있다. 본 연구는 2002년부터 시작된 <글쓰기와 읽기>, <발표와 토론> 수업 사례를 중심으로 의사소통교육의 현황을 소개하고 학생들의 리더십능력을 키워주기 위한 차원에서 실시되고 있는 의사소통센터의 다양한 프로그램들을 살펴보는데 있다. 학생들은 실습 비중이 큰 교양필수 과목을 1학년 시기에 이수함으로써 이러한 의사소통교육을 통해 사회현상에 대한 통찰력과 문제의식을 키우고, 자신의 생각을 구성하고 공적인 공간에서 설득력 있게 표현하고 전달하는 능력을 개발하고 있다. 이와 같은 의사소통능력은 숙명여대가 지향하는 S-리더십의 중요한 축인 미래형 기술(Skill)을 지닌 리더의 중요한 역량이자 자질이다. 이러한 방향에서 현재 진행되고 있는 의사소통교육이 갖고 있는 함의와 향후 S-리더십 교육의 방향에서의 시사점을 살펴보았다. Sookmyung Women's University set up "Writing and Reading" and "Presentation and Debate" courses as core electives of an educational program to foster women leaders who will practice gentle serving manner, and who will have excellent communication capabilities. Moreover, as a centralized and interdisciplinary educational program, Sookmyung Women's University has institutionalized the communication development center to educate the first year university students. This course is a fundamental education program which fulfills an intrinsic educational function of allowing students to cultivate their own ability. At the same time, an important goal is training pragmatic and talented people who best fit modern society. This paper analyzed current communication programs based on "Writing and Reading" and "Presentation and Debate" courses, and has looked over various other programs, which are dedicated to fostering students' leadership capabilities, which are operated by communication development center. Especially, this research highlighted the educational importance of campus competitions like "Sookmyung Debate Contest", started in 2002, and "Kyobo-Sookmyung the Whole Country University Students' Books discussion Contest", started in 2006, because these competitions were helpful enhancing students' communication capabilities. Through these effective education programs, students can cultivate their insight to social phenomenon and develop a critical mind to that, beyond her major. With the help of practical educational core courses which could stimulate students' thinking and expression ability, students' capability which was formulated by the communication education, will move toward S Leadership which is targeted by Sookmyung Women's University.

디지털 시대와 사이버 페미니즘 : 한국여성단체의 온라인 여성운동과 의사소통방식을 중심으로 Based on on-line activities and the communication style of Korean Women's groups in the web

신희선 숙명여자대학교 아시아여성연구소 2005 아시아여성연구 Vol.44 No.1

디지털 사회는 정보 기술과 지적 자본이 시대를 열어 가는 원동력이 된다. 제러미 리프킨(Jeremy Rifkin)의 표현처럼 접속의 시대(The age of access)'에 등장한 사이버 페미니즘(cyber-feminism)은 사이버 공간의 출현과 더불어 탄생된 여성운동의 개념이다. 정보기술의 변화가 여성의 현실에 어떻게 영향을 미칠 것인가에 관심을 두고, 익명성을 전제로 한 사이버 공간에서도 남성과 여성이 다른 대우를 받고 있다는 점과 디지털 담화내에 성별 권력차이가 존재한다는 문제인식에서 출발하였다. 여성들간의 자유로운 대화의 장을 모색하고, 여성 자신들의 필요와 욕구와 부합하는 온라인 여성운동을 통해 사이버 상에 여성 세력화를 도모할것을 강조하였다. 이에 본고는 디지털 시대의 특징과 관련하여 우리 사회의 구조적인 변화와 한국여성단테의 여성운동의 측면을 온라인 운동과 의사소통방식에 초점을 두고 진행하였다. 첫째, 인터넷 시대 사이버공간과 관련된 젠더 문제를 인식하며 새롭게 전개되고 있는 사이버 페미니즘에 주목하면서, 이른 바 '접속'에 참여하는 '닷컴세대'를 겨냥한 여성운동의 질적인 변화가 일어나고 있음을 살펴보았다. 둘째, 오랜 역사를 지닌 여성단체들이 홈페이지를 마련하면서 여성회원들만이 대상이 아니라 접속자들에게 운동의 목적을 홍보하고 정보와 자료를 공유하면서 전개하고 있는 다양한 활동을 살펴보았다. 또한 온라인상의 '여성주의 사이트'들의 수평적이고 탈권위적인 의사소통방식에 주목하였다. 다양한 여성관련 이슈와 담론들이 커뮤니티 속에서 진행되는 양상과 독특한 글쓰기 방식에서의 커뮤티케이션의 새로운 변화를 살펴보았다. 세째, 사이버 공간이 갖는 긍정적인 측면에 주목하여 인터넷이라는 공간이 여성 인권과 성 평등을 위한 소통의 장으로서 어떻게 여성운동의 지평을 넓혀가고 있는지, 사이버 페미니즘에 입각한 한국사회 여성운동의 전망과 함의, 그 가능성을 탐색해 보았다. Digital society is the driving force of Information technology and knowledge capital. As Jeremy Rifkin once mentioned, 'the age of access' shows enormous changes in social structure and mindsets. It is with this emerging of digital society that Cyber-feminism, a new concept of feminism activity, was created. This article is interested in how cyber space and the change in related information technology could influence the reality of women, while acknowledging the problem of differential treatment of male and female in cyber space and the existence of different gender power in cyber conversations. Women are searching for a new communication space that is free from male-governing structure. They are acknowledging the need for a community that conforms to their own needs and desires and protects the aggregation of women in cyber space. This paper focuses on the characteristics and communication style of on-line feminism activity of Korea womens groups in the digital era. First, the paper concentrates on how cyber-feminism connects knowledge-informational society, the Internet era and gender problems to show new directions for feminism activities. So, it begins by focusing on the qualitative changes in Korean feminism activities that are aimed at dot-com generation who participates in the so-called access. Second, this article examines the on-line activities of womens organizations with long histories, on how they started to provide information and advertise feminism to its members through their Internet Home-Pages. Also it mentions a case where a feminism site first started its activities on-line, later expanded its activities by organizing an off-line organization. Furthemore, this article investigates the changes in communication style, that is, various women related issues and discussions are becoming democratized into a bottom-up, horizontal style, and how a unique style of writing that shows sisterly affection is emerging. Third, this article focuses on the positive aspects of cyber space, on how the internet enlarged the possibility of feminism activiites by providing a communication space for womens rights and gender equality. It finishes off by mentioning the outlook, hidden meaning and possibility of feminism activities of the Korean society, based on the development of Cyber-Feminism.