Synthesis, characterization and catalytic properties of palladium-cupric oxide-aluminum oxide nanocomposites

Subhan, M. A.,Ahmed, T.,Awal, M. R.,Kim, B. Elsevier Science B.V., Amsterdam. 2014 Materials science in semiconductor processing Vol.24 No.-

APPLICABILITY OF KNOWLEDGE-BASED INNOVATION SYSTEM IN BANGLADESH

SUBHAN TAHRIMA,제갈돈 한국행정학회 2013 International Review of Public Administration Vol.18 No.3

The changing world requires positive change in every sector through knowledge-based innovation to successfully sustain. Knowledge-based innovation, the spirit of making things better and more sustainable using intellectual aspects, is essentially a transformation strategy for developing countries to shape their competitive standing in the present globalized environment. But Bangladesh is far behind the expected level of a knowledge-based innovative society. Lack of advanced education and technology, lack of combination of theory and practice and knowledge-sharing mechanisms, lack of proper financing in industry, lack of mutual interaction between university and industry, lack of an innovative role played by government and constructive regulatory control are among the factors diminishing the country’s strength to move towards knowledge-based innovation and global advancement. According to the Triple Helix model of knowledge-based innovation, interaction among different actors of three sectors—university, industry, and government—generates a country’s innovation process as well as its development progress. Therefore, it is essential for Bangladesh to go beyond the obsolete approach of development to establish a modern and knowledge-based innovation system. This study focuses on the applicability of a knowledge-based innovation system in the context of Bangladesh, and attempts to sketch out a suitable model for knowledge-based innovation in the perspective of Bangladesh.

Antinociceptive and gastro-protective effect of the ethanolic extract of the flowering top of Anthocephalus Cadamba Roxb

Subhan, Nusrat,Hasan, Raquibul,Hossain, Mokarram,Akter, Raushanara,Majumder, Muntasir Mamun,Rahman, Mostafizur,Ahmed, Kamaluddin,Ghani, Abdul,Alam, Ashraful Kyung Hee Oriental Medicine Research Center 2009 Oriental pharmacy and experimental medicine Vol.9 No.4

The effect of alcoholic extract of Anthocephalus (A.) Cadamba Roxb. was evaluated in experimental models of pain and ulcer. Hot tail flick test, hot plate test and acetic acid induced writhing test were employed for evaluating the peripheral as well as central analgesic mechanism exerted by the extracts. Gastroprotective activity was examined by HCl and ethanol induced gastric damage test. Test group received crude extract 500 mg/kg showed maximum time needed for the response against thermal stimuli (6.26 ${\pm}$ 0.439 s) which is comparable to diclofenac sodium (6.56 ${\pm}$ 0.381 s) in hot tail flick method. These experimental results also followed the experimental results of hot plate test where crude extract 500 mg/kg showed maximum time needed for the response against thermal stimuli (4.74 ${\pm}$ 0.234 s) which is comparable to diclofenac sodium (5.58 ${\pm}$ 0.585 s). The crude extract at 500 and 250 mg/kg showed significant reduction in acetic acid induced writhing in mice with a maximum effect of 68.026% reduction at 500 mg/kg dose which is comparable to standard diclofenac sodium (79.93%). In gastroprotective study the extract of A. Cadamba (250 and 500 mg/kg) significantly inhibited ulceration induced by both HCl and ethanol dose dependently. Results of the study suggest that the extract possesses both analgesic and gastroprotective activity on mice.

Fish Scale Collagen Peptides Protect against CoCl ₂ /TNF- <i>α</i> -Induced Cytotoxicity and Inflammation via Inhibition of ROS, MAPK, and NF- <i>κ</i> B Pathways in HaCaT Cells

Subhan, Fazli,Kang, Hae Yeong,Lim, Yeseon,Ikram, Muhammad,Baek, Sun-Yong,Jin, Songwan,Jeong, Young Hun,Kwak, Jong Young,Yoon, Sik Hindawi 2017 Oxidative medicine and cellular longevity Vol.2017 No.-

<P>Skin diseases associated with inflammation or oxidative stress represent the most common problem in dermatology. The present study demonstrates that fish scale collagen peptides (FSCP) protect against CoCl<SUB>2</SUB>-induced cytotoxicity and TNF-<I>α</I>-induced inflammatory responses in human HaCaT keratinocyte cells. Our study is the first to report that FSCP increase cell viability and ameliorate oxidative injury in HaCaT cells through mechanisms mediated by the downregulation of key proinflammatory cytokines, namely, TNF-<I>α</I>, IL-1<I>β</I>, IL-8, and iNOS. FSCP also prevent cell apoptosis by repressing Bax expression, caspase-3 activity, and cytochrome c release and by upregulating Bcl-2 protein levels in CoCl<SUB>2</SUB>- or TNF-<I>α</I>-stimulated HaCaT cells. In addition, the inhibitory effects of FSCP on cytotoxicity and the induction of proinflammatory cytokine expression were found to be associated with suppression of the ROS, MAPK (p38/MAPK, ERK, and JNK), and NF-<I>κ</I>B signaling pathways. Taken together, our data suggest that FSCP are useful as immunomodulatory agents in inflammatory or immune-mediated skin diseases. Furthermore, our results provide new insights into the potential therapeutic use of FSCP in the prevention and treatment of various oxidative- or inflammatory stress-related inflammation and injuries.</P>

Bias-dependent transport properties of passivated tilted black phosphorene nanoribbons

Subhan, F.,Farooq, M. U.,Hong, J. Royal Society of Chemistry 2018 Physical chemistry chemical physics Vol.20 No.16

<P>Using the density functional theory incorporated with a non-equilibrium Green's function (NEGF) technique, we explored the bias-dependent transport of tilted phosphorene nanoribbons. Herein, we considered three types of nanoribbons: self-passivated (TPNRself), H-passivated (TPNRH), and O-passivated (TPNRO) systems. The TPNRself showed an indirect band gap of 0.53 eV, whereas the TPNRH displayed a direct band gap of 1.32 eV. In TPNRO, we observed a spin-polarized band structure with a spin-dependent band gap. We found that the bias-dependent I-V curve was dependent on the passivation effect. In TPNRself and TPNRH, the current monotonically increased with an external bias, but the magnitude of the current in TPNRself was more than 10 times than that in TPNRself. Unlike the I-V characteristics in TPNRself and TPNRH, the current in TPNRO almost vanished beyond an external bias of 1.7 V. Mostly, the bias-dependent I-V was interpreted based on the band structure in the lead parts. However, we found that this conventional approach was not sufficient to analyze the I-V curve. Indeed, we showed that the detailed I-V curve could be understood by calculating the bias-dependent density of states in the scattering part related to the transmission channel. It was also found that the electron flow channel was dependent on the passivation effect and uniformly distributed over the entire nanoribbon in TPNRself and TPNRH. In contrast, the electron flowed mostly along the edge line in TPNRO. Moreover, we have found that spin polarization in the conduction current can be manipulated by an external bias, and this may suggest that the TPNRO can be utilized for potential spintronic applications.</P>

Structure and photoluminescence studies of CeO₂.CuAlO₂ mixed metal oxide fabricated by co-precipitation method

Subhan, M.A.,Ahmed, T.,Awal, M.R.,Kim, B.M. Pergamon 2015 Spectrochimica acta. Part A, Molecular and biomole Vol.135 No.-

A novel mixed metal oxide, CeO<SUB>2</SUB>.CuAlO<SUB>2</SUB> was fabricated by co-precipitation method in aqueous medium. CeO<SUB>2</SUB>.CuAlO<SUB>2</SUB> was characterized by XRD, SEM, EDS, TEM, FTIR and PL spectra. The optical properties of the nanoparticles were studied by photoluminescence (PL) spectra. PL spectra at different excitations were recorded. The composite showed emission in UV, visible and NIR region depending on the excitation wavelength. The special spectral feature observed for this composite is that it showed six emission bands at 364, 409, 434, 448, 465 and 481nm when excited at 298nm. The green and red emissions observed at 512 and 669nm are originated from cubic CeO<SUB>2</SUB> phase when excited at 450nm. The PL spectra were found to be dependent on excitation wavelength violating Kasha's rule. The X-ray diffraction reveals a cubic CeO<SUB>2</SUB> phase and hexagonal CuAlO<SUB>2</SUB> phase. EDS spectra revealed the presence of cerium (Ce), copper (Cu), aluminum (Al) and oxygen (O) elements. The particle size of the CeO<SUB>2</SUB>.CuAlO<SUB>2</SUB> mixed oxide was estimated using Scherrer's formula, which was found to be in the range of 17.2-34.2nm. The TEM image showed particles are almost uniform size of approximately 15-50nm with spherical morphology.

Epidermal growth factor-like domain 8 inhibits the survival and proliferation of mouse thymocytes

SUBHAN, FAZLI,YOON, TAE-DEUK,CHOI, HEE JUNG,MUHAMMAD, IKRAM,LEE, JIEUN,HONG, CHANGWAN,OH, SAE-OCK,BAEK, SUN-YONG,KIM, BONG-SEON,YOON, SIK Spandidos Publications 2013 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol.32 No.4

<P>Thymic epithelial cells (TECs) play a critical role in T-cell development through their intercellular interactions and by producing various soluble proteins, such as growth factors, cytokines and chemokines. In this study, we report a new role for epidermal growth factor-like domain 8 (EGFL8) in the regulation of the survival and proliferation of mouse thymocytes. Mouse recombinant EGFL8 (rEGFL8) protein was produced using an E. coli system and its biological role in mouse thymocytes was determined. The injection of rEGFL8 in mice in vivo resulted in a decrease in the weight of the thymus, as well as in the number of total thymocytes; rEGFL8 also inhibited thymocyte proliferation and induced thymocyte apoptosis. Furthermore, rEGFL8 suppressed the expression of the Notch downstream targets, Hes1 and Hey1, in mouse thymocytes and TECs, indicating that EGFL8 negatively regulates the Notch signaling pathway in these cells. The identification of the role of EGFL8 in thymocytes may aid in the determination of the fate of thymocytes during T-cell development.</P>

Determination of Optimal Toxic Concentration and Accumulation of Cadmium in Broiler Chicks

Subhan, Fazli,Khan, Ayaz,Wahid, Fazli,Shehzad, Adeeb,Jan, Amin Ullah Korean Society of ToxicologyKorea Environmental Mu 2011 Toxicological Research Vol.28 No.3

Cadmium is considered one of the most toxic, non biodegradable heavy metal for the human and animals. The purpose of the present study was to investigate the changes in biochemical parameters of blood and accumulation of cadmium in various tissue caused by various levels of dietary cadmium chloride ($CdCl_2$) in broiler chicks. $CdCl_2$ was administered through drinking water to broiler chicks. In spectral analysis, $CdCl_2$ treatment caused a significant increase in Glutamate pyruvate transaminase (GPT), creatinine and uric acid levels in all treated groups. Intriguingly, the GPT, creatinine, and uric acid levels were significantly higher at 75 mg/kg as compared to the groups treated with high doses (100, 125 and 150 mg/kg) of $CdCl_2$. Atomic Absorption Spectrophotometer (AAS) was used for the determination of Cd accumulation in kidney, liver and Breast muscles. AAS analysis revealed that Cd accumulation is increased in breast muscles as compared to liver and kidney at higher doses of Cd than 75 mg/kg.

Challenges for Government Innovation in Bangladesh

Subhan Tahrima,제갈돈 서울대학교행정대학원 2012 Journal of Policy Studies Vol.27 No.2

Innovation is not self-generating or self-sustaining. Successful innovation requires leadership to establish organizational capacity to generate ideas and to ensure prompt and effective service. If any government fails to provide these supports to the innovation process, it will not be effective. This paper seeks to identify factors that hamper government innovation in Bangladesh. It proposes a strategy for the Bangladesh government that involves political institutionalization, administrative and market decentralization, promotion of social and economic justice, and good governance in order to promote innovation processes and ensure successful innovation flows within the country.

방글라데시에서 행정의 최근 이슈와 과제

( Subhan Tahrima ),제갈돈 ( Don Jaegal ),김병규 ( Byungkyu Kim ) 한국세계지역학회 2015 世界地域硏究論叢 Vol.33 No.2

행정은 어떤 민주적 거버넌스 시스템에서도 활력의 원천이며, 행정이 정부의 성공 여부를 결정한다. 오늘날 세계의 모든 국가들은 지역과 글로벌 차원에서의 도전에 대응하여 그들의 행정시스템을 개혁하려고 노력하고 있다. 1971년 이래로 국민국가로서 방글라데시 또한 글로벌화, 복지, 그리고 발전을 위한 올바른 진로를 추구하기 위하여 행정시스템을 재구성하기 위한 힘든 노력을 강구하고 있다. 정말로 방글라데시의 행정은 발전과 분권화의 과정에서 다양한 형태의 정부에 의하여 많은 긍정적 혹은 부정적 개혁을 접하였다. 그 후 방글라데시의 행정은 유능하고 혁신적인 인적 자원의 부족과 수십 년에 걸친 모든 정부 메커니즘분야에서 매우 잘못된 정치적 실행 때문에 허약한 상태로 남아 있다. 이것들로 인하여 현재방글라데시 공공거버넌스와 행정은 심각한 위기에 처해 있다. 이 논문은 혁신적인 약속을 통한 방글라데시 행정 상황의 현대화와 발전을 향한 노력이다. 이 논문은 강력한 지식기반과 긍정적 정치화 과정을 강조할 뿐만 아니라 방글라데시에서 능률적, 일관적, 그리고 신뢰적인 행정을 확보하기 위하여 공공서비스에서의 삼중나선관계(triple helix relation)를 소개하면서 지식기반 개혁안을 제시하려고 시도한다. 정치와 전체 정부의 발전과의 관계는 제안을 분명히 하기 위하여 이 연구에서 구체화할 것이다. Public administration is the vigor of any democratic governance system. It determines the success of the government. In today’s world, all countries strive to reform their administrative system in response to the local and global challenges. Since 1971, as a nation-state, Bangladesh is also trying hard to reshape its public administrative system in order to pursue the right track of globalization, welfare and development. Indeed, the public administration in Bangladesh faced many positive and negative reforms by various form of governments on the way to development and democratization. After that, the state of public administration in Bangladesh remains frail because of absent of qualified and innovative human resources and excessive ill practice of politics in every sphere of government mechanism over the decades. These have brought grave crisis for existing public governance and administration in Bangladesh. This paper is an effort towards the modernization and development of the status of public administration in Bangladesh through an innovative arrangement. This paper attempt to sketch the knowledge based reform proposal emphasizing on strong knowledge foundation and positive politicization process as well as introducing a triple helix relation among civil service to ensure an efficient, consistent and creditable public administration in Bangladesh. The relation between politics and the development of entire government system has been specified in this study to make the proposal evident.