Solar urticaria in Korean patients

( Sung Min Kim ),( Young Ah Cho ),( Ji Su Lee ),( Ji Youn Hong ),( Jin Hee Kim ),( Joo Ran Hong ),( Hye In Cheon ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1

Background: Solar urticaria (SU) is an uncommon type of photodermatoses characterized by erythematous wheal with pruritus after sunlight exposure, which shows a female predominance. Only a few studies to analyze the clinical features of SU were reported in Asia. Objectives: We aimed to analyze the clinical and photobiological characteristics of SU in Korea. Methods: We retrospectively investigated the medical records of patients with SU who visited the department of dermatology, Konkuk university medical center from January 2005 to January 2020. Results: Of a total of 44 patients, 36 (81.8%) were male and 8 (18.2%) were female. The mean age at onset was 17.6 years (range, 5-47) and the mean threshold time was 19.7 minutes. Among 32 patients who underwent phototesting, the action spectrum most commonly implicated was ultraviolet (UV) A only in 12 (37.5%), and then visible light (415nm) only was responsible for SU in 8 (25.0%). Three patients (9.4%) were induced by both UVA and visible light (415nm). Even 4 patients (12.5%) were triggered by only natural sunlight. Serum immunoglobulin E levels were measured in 33 patients, and 17 (51.5%) showed values higher than normal. The treatment most widely used were oral antihistamine (43.2%), followed by phototherapy (13.6%). Conclusion: SU is a rare photodermatosis in Korea, which shows a male preponderance. In this study, UVA and visible light (415nm) were predominant action spectrum of SU.

Genome-wide investigation of a Korean synthetic breed, Woori-Heukdon using the Illumina PorcineSNP60K BeadChip

Yong‑Min Kim,Ha‑Seung Seong,Jung‑Jae Lee,Da‑Hye Son,Jin‑Su Kim,Soo‑Jin Sa,Young‑Sin Kim,Tae‑Jeong Choi,Kyu‑Ho Cho,Joon‑Ki Hong,Jung‑Woo Choi,Eun‑Seok Cho 한국유전학회 2020 Genes & Genomics Vol.42 No.12

Background: Woori-Heukdon (KWH) is a Korean synthetic pig breed generated using Chookjin-Duroc (KCD), Chookjin-Chamdon (KCC), and their crossbreds. Currently, there is a severe lack of studies investigating the Korean breed populations including wild boars (KWB) throughout the genome. Objective: This study was performed to investigate the genetic characteristics of Korean pig populations at the genome-wide level. Methods: Using the SNP dataset derived from genotyped and downloaded datasets using the Illumina PorcineSNP60K BeadChip, we compared the genomes of 532 individuals derived from 23 pig breeds to assess the genetic diversity, inbreeding coefficient, genetic differentiation, and population structure. Results: KWB showed the lowest average expected heterozygosity (HE = 0.1904), while KWH showed the highest genetic diversity (HE = 0.02859) among Korean populations. We verified that the genetic composition of KWH, showing USD of 74.8% and KCC of 25.2% in ADMIXTURE analysis. In population structure analyses, KCC was consistently shown to be separated from other pig populations. In addition, we observed gene flow from Western pigs to a part of Chinese populations. Conclusion: This study showed that Korean native pigs, KCC have genetic differences in comparison with Chinese and Western pigs; despite some historical records and recent genetic studies, we could not find any clear evidence that KCC was significantly influenced by Chinese or Western breeds in this study. We also verified the theoretical genomic composition of KWH at the molecular level in structure analyses. To our knowledge, this is the first genomic study to investigate the genomic characteristics of KWH and KCC.

Selective hydrogen oxidation reaction catalysts approach to enhance the durability of PEMFC for FCEV under the condition of SU/SD and fuel starvation

Su Won Yun(윤수원),Ki Woong Park(박기웅),Tae June Kim(김태준),Byung Il Park(박병일),Gwon Goo Yeo(여권구),Hoon Hee Lee(이훈희),Bum Wook Roh(노범욱),Yong Tae Kim(김용태) 대한기계학회 2016 대한기계학회 춘추학술대회 Vol.2016 No.4

LCC 기법을 이용한 신기술 에너지 절약기기의 적용 사례에 대한 경제성 평가 : 바닥 난방시스템을 중심으로 Focused on the Apartment Floor Heating System

황성수,김용혁,김용수 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

The purpose of this study is to assess economic effect for the application of a new technology-based energy economizer Memo Valve from "I" company. The study has been performed using LCC technique for the economic assessment. Data for LCC analysis are collected from questionnaire survey and interview for the estimating and maintenance experts of apartment building. Based on the LCC analysis, the economic effect of Memo Valve has been predicted as follows: 9.5% of LCC saving, and 19 times return rate for the investment during 50 years of study period.

두경부 편평세포암에서 형질전환 성장인자-알파(TGF-α)의 발현에 관한 연구

도남용,이승학,김완수,김경일,이동용,김용기,최봉남 조선의대 1996 The Medical Journal of Chosun University Vol.21 No.2

PCR을 이용한 국내 및 수입 축산물 유래 Listeria monocytogenes의 유전학적 분석연구

우용구,이수화,이철현,최정수,류재두,김영일,이오수,김봉환 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.2

One hundred-fifty two of Listeria strains were isolated from domestic chicken carcasses, a slaughter-houses from nationwide from 1996 to 1997 and imported livestock products from a ten foreign countries including the USA, China, France and Thailand. To substitute the laborious and time consuming procedures of clinical laboratory standard diagnostic methods, the rapid and specific multiplex PCR(M-PCR), which was designed to amplify a three kinds of genes simultaneously f3r specific detection and differentiation of L. monocytogenes(LM) by one step procedure, was established. The LM strains confirmed with M-PCR were analysed to their genetic diversities by RAPD using the two primers(D87 & MMTl), and also evaluated on their discriminatory abilities(na) between two primers. our study also conducted the REP-PCR and ERIC-PCR for evaluation of the possibility of REP and ERIC elements for genetic subtyping of LM strains. According to the REP-PCR and ERIC-PCR fingerprinting patterns, LM strains were divided into 7(ERIC-type) and 4(REP-type) major clusters at the relative clone cut off value of 80%. According to the computer analysis of PCR results using the GelCompar Ⅱ software, ERIC-PCR(DI=0.955) had expressed the most high discriminatory ability and followed by REP-PCR(DI=0.952), RAPD(D87; 0.954, MMT1; 0.937), in order. The combined analysis of the present PCR results was also expressed the reliable and useful discriminatory ability(DI=0.916). This study suggested that PCR based methods could be used as an reliable, reproducible, rapid, and highly discriminatory method for the genetic differentiation of genus Listeria.

유망한 당근 돌연변이, 무모종자

박용(Yong Park),조문수(Moon Soo Cho),김용수(Yong Su1 Kim),박상규(Sang Gyu Park) 한국원예학회 2002 한국원예학회 학술발표요지 Vol.2002 No.3

후두 및 하인두 암종에서 p53단백 발현과 Espstein-Barr Virus 검출

최영환,도남용,나한조,이도용,노용훈,김완수,최종선 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Background and Objectives : When p53 cancer suppressor gene, occurs gene deletion or point mutation, malignancy develops by loss of p53 function with abnormal p53 protein. The Epstein-Barr virus (EBV) is the causative agent of certain type of lymphoma and undifferentiated nasopharyngeal carcinoma. However, the role of EBV as a causative factor in other head &eck tumors is not fully elucidated except nasopharyngeal carcinoma. This study, the author examined that p53 expression and detection rate of EBV correlate to development of laryngeal and hypopharyngeal squamous cell carcinoma(SCC) and play the possible role of prognostic indicators. Materials and Methods : Formalin-fixed, paraffin-embedded tissue specimen from 32 cases of larynx and hypopharyngeal squamous cell carcinomas were studied by immunohistochemical staining for p53 and EBV. The results of analysis were compared with clinicopathological parameters. Results : p53 expression was 56.3% (18 cases) and the detection rate of EBV was 43.6% (14 cases) of 32 cases in laryngeal and hypopharyngeal squamous cell carcinomas. p53 expression was correlate with histologic grade (p<05) only. Detection of EBV was not correlate with clinicopathological parmeters. Conclusion : These results suggest p53 expression and the detection of EBV may be related with development of laryngeal and hypopharyngeal squamous cell carcinoma. And, the expression of p53 protein can be used as a prognosticator in laryngeal and hypopharyngeal squamous cell carcinoma under certain limitation.

조선시대 주칠죽장연함의 수리

이용희,유혜선,김경수 국립중앙박물관 2000 박물관보존과학 Vol.2 No.-

국립중앙박물관 보존과학실에서는 벼루, 먹, 연적 등을 넣어 보관하는 조선시대 주칠죽장연함을 전통 목·칠공예기법으로 수리 복원하였다. 수리 이전의 전통적인 제작기법을 그대로 되살리기 위해 바탕목재의 재질과 결구방식, 칠의 재료와 기법, 문양의 구성 등을 조사하였다. 특히 이번에 수리한 주칠죽장연함은 부분적으로 손상된 칠면의 완벽한 복원이 가장 중요한 과제였으므로 표면 칠에 대한 조사에 중점을 두었다. 먼저 칠 기법을 조사하기 위해 연함으로부터 탈락된 칠도막 시료를 박편으로 가공하여 투과광현미경으로 관찰하였고, SEM-EDS와 X-선회절분석기로 칠에 혼합된 안료의 성분을 분석하였다. 그 결과 연함은 오동나무로 만든 목재바탕 표면에 얇게 가공한 대나무로 문양을 장식하고 그 여백에는 석간주(Fe₂O₃, Hematite)와 진사(HgS, Cinnabar)를 혼합한 주칠을 여러 차례 반복한 것으로 나타났다. Conservation Science Lab. of the National Museum of Korea recovered Bamboo-plated inkstone case which is used for keeping inkstick, inkstone and inkstone water container by using traditional lacquering and wooden art technology. Texture and construction method of wood, ingredients for lacquering and the method, and the design were analyzed in order to restore the original manufacturing method. Especially, perfect restoration of partially damaged lacquer surface is the most important aspect in restoring Bamboo plated inkstone case, therefore focus was put on investigation of surface lacquering. First, lacquering surface sample was taken off from the object and processed into flake and observed with trans mission microscope in order to investigate lacquering method and the pigment in the lacquering surface was analyzed with XRD and SEM-EDS. The result showed that the object was decorated with thin layered bamboo in the surface which is made of Royal paulownio. and lacquered several times with the mixture of Hematite(Fe₂O₃) and Cinnabar(HgS) in the remaining part.

수침고목재의 보존을 위한 PEG, Sucrose, Lacitol 처리 및 습도조건에 따른 상태변화 실험

이용희,김수철,박영만,김경수 국립중앙박물관 2000 박물관보존과학 Vol.2 No.-

광주 신창동 저습지유적에서 출토된 수침목재유물에 적합한 보존처리 방법을 설정하고자 동일유적에서 출토된 2종의 자연목재를 PEG(Poly-Ethylene Glycol), Sucrose, Lactitol로 처리하고 약제별 치수안정성 및 처리목재의 습윤↔건조 특성을 상호 비교하였다. 그 결과 상수리나무류는 저분자의 PEG#200(MW:200)과 고분자량의 PEG#4000(MW:3,350)을 이용한 2단계 PEG처리(PEG-2Step)에서, 단풍나무류는 PEG#4000만을 단독으로 적용한 처리에서 가장 높은 치수안정성을 나타내었다. 또한 처리 후 습윤↔건조 실험에서는 2단계 PEG처리한 시험재의 치수변화가 가장 작게 나타났다. 반면 Sucrose와 Lactitol의 경우 약제 확산속도가 빠르지만 Sucrose처리재는 84%의 높은 습도조건에서 흡습량이 급격히 증가하면서 약제가 다량 용출되었고, Lactitol은 습윤↔건조 후 미세한 할렬과 함께 처리재가 팽창되는 현상이 발생되었다. 또한 습윤↔건조 실험에서 2단계 PEG처리를 제외한 모든 시험재에서 갈라짐이 발생하였다. 이번 실험결과 신창동 저습지 출토수침목재는 2단계 PEG처리법을 적용한 경우에 치수안정성이 가장 높고 습도변화에 대한 적응성도 양호한 것으로 나타났다. In order to studies proper conservation treatment condition of waterlogged archaeological wood excavated from wetland in Shinchang-dong, Gwangju, 2 kinds of wooden objects were treated with PEG(Poly-Ethylene Glycol), sucrose and lactitol and their size stability and relative humidity were analyzed and compared each other. The result showed that Quercus spp. had the highest size stability in 2 Step PEG treatment using PEG#200(MW:200) and PEG#4000 (MW:3,350) and Acer spp. was the highest in treatment using only PEG#4000. In relative humidity test after treatment 2 Step-PEG treatment showed the lowest size stability. In the meantime, sucrose and lactitol-treated sample was fast for penetration, sucrose-treated sample showed a sharp increase for penetration in as high as 84% humidity condition and medicine flew out a lot and lactitol-treated sample got enlarged with fine cracking(splitting) in relative humidity test. In relative humidity test, the samples showed cracking(splitting) in all treatment materials except for 2 Step-PEG treatment. This study showed that waterlogged archaeological wood excavated from Shinchang-dong had the highest size stability and highest adaptation to humidity change in case of treatment with 2 Step-PEG.