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Hyun, Kwan-Hoon,Kwack, In-Young,Lee, Do-Young,Park, Hyung-Yeon,Lee, Bon-Su,Kim, Chan-Kyung Korean Chemical Society 2004 Bulletin of the Korean Chemical Society Vol.25 No.12
Ligand-based quantitative structure-activity relationship (QSAR) studies were performed on indolinones derivatives as a potential inhibitor of the protein tyrosine kinase of fibroblast growth factor receptor (FGFR) by comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) implemented in the SYBYL packages. The initial X-ray structure of docked ligand (Su5402) to FGFR was used to minimize the 27 training set molecules using TRIPOS force field. Seven models were generated using CoMFA and CoMSIA with grid spacing 2 ${\AA}$. After the PLS analysis the best predicted CoMSIA model with hydrophobicity, hydrogen bond donor and acceptor property showed that a leave-one out(LOO) cross validated value $({r^2}_{cv})^$ and non-cross validated conventional value $({r^2}_{ncv})^$ are 0.543 and 0.938, respectively.
콩에서 발생하는 강낭콩일반모자이크바이러스(BCMV)와 땅콩위축바이러스(PSV)의 저항성 평가
이영훈, 윤영남, 강범규, 김현영, 최만수, 구성철, 김현태, 윤홍태, 이수헌, 백인열 忠北大學校 農業科學硏究所 2014 農業科學硏究 Vol.30 No.2
It has been reported several viral diseases in soybean. The occurrence of Bean common mosaic virus and Peanut stunt virus are able to induce severe problem because the main breeding target for viral disease was focused on Soybean mosaic virus. BCMV is a spcies of the genus Potyvirus of the family Potyviridae. BCMV reduces yield by as much as 80% and also adversely affects seed quality in common bean. BCMV has a worldwide distribution because of its high rates 35% of transmission via seeds produced by plants systemically infected prior to bloom. PSV is a species of the genus Cucumovirus of the family Bromoviridae. PSV has been reported to be economically damaging on beans worldwide. Although the virus is reportedly seed transmissible at very low rates, infected plants rarely produce pods with normal viable seeds. The most satisfactory management method of viral diseases such as BCMV and PSV is the use of resistant cultivars and healthy seed. For the overcome of genetic resistance by new virus such as BCMV and PSV, virus diseases monitoring and researches need to study deeply and continually. In this study, we conducted the resistance screen on BCMV and PSV for selection of resistance cultivars. We inoculated on 128 cultivars with PSV and BCMV respectively. These cultivars were classified through pathogenic response such as resistance, necrosis and susceptibility. In addition, 99 and 66 resistant cultivars were confirmed against PSV and BCMV respectively.
이상훈,김수연 대구대학교 정보통신연구소 2012 情報通信硏究 Vol.9 No.1
본 논문은 다기준 의사결정 기법의 하나인 계층분석과정(AHP: Analytic Hierarchy Process)을 이용 하여 입지평가 모형을 수립하고 이에 대한 실증분석을 실시한다. 먼저 기존 연구를 통하여 입지선정 이 잘 이루어졌는지 확인하기 위한 평가요소를 도출하고 이를 이용하여 대학 사례에 대한 입지선정 평가모형을 수립한다. 평가요소들 간의 상대적 중요도를 파악하고 AHP를 적용하여 각 대안들 간의 우선순위를 산출한다. 대학 사례를 통하여 평가기준별 순위와 전체적인 순위를 제시하고 이에 따른 대학별 대응전략을 제시한다. 마지막으로 본 연구의 결과를 요약하고 향후 연구방향을 제시한다. This paper conducts an empirical analysis of location assessment using AHP(analytic hierarchy process), one of multi-criteria decision making techniques. First, we identify assessment criteria to evaluate location selection from literature review and establish a model of university location assessment based on identified criteria. Relative importance of each evaluation criterion is derived and then priorities of all possible alternatives are calculated. We rank each alternative by evaluation criteria and overall and propose responding strategies of the universities based on the evaluation results. Finally, we summarize the research and present future research direction
이수경,김종훈,최종운,이정훈 韓國火災ㆍ消防學會 1998 한국화재소방학회논문지 Vol.12 No.3
본 연구는 실제 화재실험을 통하여 구획 화재 시 일어날 수 있는 창유리의 파괴 형태 및 시간 그리고 개구 조건과의 관계 등을 고찰하고자 했다. 화재 시 창유리의 파괴현상은 창호 유리 중간 부분과 프레임 안에 있는 유리부분의 현저한 온도차이로 인한 열응력으로 일어남을 확인했다. 실험 1-3은 프레임 내부와 유리면의 온도차가 233.4℃ 였으며, 실험 2-1은 138℃, 실험 2-2는 83.6℃의 차이를 보였다. 파괴 발생 시 실내의 온도는 실험 2-1의 경우 434.4℃, 실험 2-2는 83.6℃의 차이를 보였다. 파괴 발생 시 실내의 온도는 실험 2-1의 경우 434.4℃, 실험 2-2는 440.6℃ 실험 2-3은 400.9℃를 기록하여 화염이 직접 닿지 않는 경우의 균열은 400 ~ 500℃의 온도에서 발생한다. 화재로 인한 창유리(한글라스 플로팅 유리)는 1541.14kW의 화재에 노출되었을 시 열응력에 의한 파괴가 일어나기는 하나 유리면이 파괴에 의해 개구부가 되지 않는다. This is a study on the relation of window glass breaking time, shape, and vent condition in a compartment fire through the experiment. We recognize the phenomenon that window glass breakage in a compartment fire be arose from the thermal stresses due to the temperature temperature difference was 233.4℃ for test 1-3, 138℃ for text 2-1, 83.6℃ for test 2-2. The interior test 2-2, 400.9℃ for test 2-3. so if the flame didn't reach at the surface of window glass, the breakage of glass occur at 400℃ ~ 500℃. When the fire size reached to 1541.14kW, the window might be broken by thermal stress. But window glass was not collapsed.