OMICS approaches in cardiovascular diseases: a mini review

Sohag, Md. Mehadi Hasan,Raqib, Saleh Muhammed,Akhmad, Syaefudin Ali Korea Genome Organization 2021 Genomics & informatics Vol.19 No.2

Ranked in the topmost position among the deadliest diseases in the world, cardiovascular diseases (CVDs) are a global burden with alterations in heart and blood vessels. Early diagnostics and prognostics could be the best possible solution in CVD management. OMICS (genomics, proteomics, transcriptomics, and metabolomics) approaches could be able to tackle the challenges against CVDs. Genome-wide association studies along with next-generation sequencing with various computational biology tools could lead a new sight in early detection and possible therapeutics of CVDs. Human cardiac proteins are also characterized by mass spectrophotometry which could open the scope of proteomics approaches in CVD. Besides this, regulation of gene expression by transcriptomics approaches exhibits a new insight while metabolomics is the endpoint on the downstream of multi-omics approaches to confront CVDs from the early onset. Although a lot of challenges needed to overcome in CVD management, OMICS approaches are certainly a new prospect.

Repositioning Vitamin C as a Promising Option to Alleviate Complications associated with COVID-19

Farjana Mithila,Moni Akhi,Sohag Abdullah Al Mamun,Hasan Adeba,Hannan Md. Abdul,Hossain Md. Golzar,UDDIN MD JAMAL 대한감염학회 2020 Infection and Chemotherapy Vol.52 No.4

Vitamin C, also known as L-ascorbic acid, is an essential vitamin with pleiotropic functions, ranging from antioxidant to anti-microbial functions. Evidence suggests that vitamin C acts against inflammation, oxidative stress, autophagy chaos, and immune dysfunction. The ability to activate and enhance the immune system makes this versatile vitamin a prospective therapeutic agent amid the current situation of coronavirus disease 2019 (COVID-19). Being highly effective against the influenza virus, causing the common cold, vitamin C may also function against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and its associated complications. Severe infections need higher doses of the vitamin to compensate for the augmented inflammatory response and metabolic demand that commonly occur during COVID-19. Compelling evidence also suggests that a high dose of vitamin C (1.5 g/kg body weight) in inflammatory conditions can result in effective clinical outcomes and thus can be employed to combat COVID-19. However, further studies are crucial to delineate the mechanism underlying the action of vitamin C against COVID-19. The current review aims to reposition vitamin C as an alternative approach for alleviating COVID-19-associated complications.

Performance Assessment of a Block Cipher Encryption based Channel Encoded Cooperative MIMO MCCDMA Wireless Communication System

Joarder Jafor Sadique,Sohag Sarker,Shaikh Enayet Ullah 보안공학연구지원센터 2014 International Journal of Future Generation Communi Vol.7 No.1

Impact of the endophytic and rhizospheric bacteria on crop development: prospects for advancing climate-smart agriculture

Hossain Amzad,Hassan Zahid,Sohag Mehadi Hasan,Khan Mursalin 한국작물학회 2023 Journal of crop science and biotechnology Vol.26 No.4

The exploration of knowledge for crop improvement has been a continuous practice to address the food insecurity of the growing human population, and the necessity of the new knowledge is crucial due to decreasing arable land and climate change. The proper use of technology and knowledgebase has the potential to narrow down poverty in the world, more specifcally in developing countries. This review aimed to assess the role of the endophytic and rhizospheric bacteria as a potential crop improvement tool in climate-smart agriculture. Endophytic and rhizospheric were found to be efcient alternatives to the chemical-based solution to develop crops. Endophytic and rhizospheric bacteria have improved many agronomic traits such as yield, quality, disease resistance, and stress tolerance. Besides, we discussed the recent development of the feld-level application of endophytic and rhizospheric bacteria. These bacteria have potential since they are efcient in developing crops signifcantly without afecting the environment in a deleterious way. In terms of biodiversity, natural resources such as endophytic and rhizospheric bacterial application to crops are unlikely to afect the non-target species. Hence, endophytic and rhizospheric bacteria application in crop improvement is applicable for agricultural development, thereby ensuring food sustainability without afecting the environment, eventually leading us to climatesmart agriculture. This review aims to recapitulate the current knowledge and prospects of endophytic and rhizospheric bacteria to achieve the goal of climate-smart agriculture

Shifting Cultivation Effects on Soil Environment in Upland Watershed of Bangladesh

S.M. Sirajul Haque,Sanatan Das Gupta,Sohag Miah 강원대학교 산림과학연구소 2014 Journal of Forest Science Vol.30 No.2

This research reports the effects of shifting cultivation on soil environment collecting samples from 0-5 cm soil depth from five locations viz. at Burburichhara, Maichchari, Longadu, Sukurchhari and Muralipara in Rangamati district of Chittagong Hill Tracts (CHTs). Soil analyses showed that fungal and bacterial population, microbial respiration and active microbial biomass, maximum water holding capacity, conductivity and moisture contents were significantly (at least p≤0.05) lower in shifting cultivated soil compared to adjacent mixed tree plantations at all the sites. On an average in soils of 5 different shifting cultivated lands fungal population was 1.33x105 CFU/g dry soil and bacterial population 1.80x107 CFU/g dry soil and in mixed plantations fungal population was 1.70x105 and bacterial population 2.51x107 CFU/g dry soil. Organic matter and exchangeable Ca and Mg contents were significantly (at least p≤0.05) lower and bulk density significantly (at least p≤0.05) higher in shifting cultivated land in most of the locations compared to adjacent mixed tree plantations. Ratios of microbial respiration and organic carbon as well as active microbial biomass and organic carbon were distinctly lower and pH higher at 3 locations in shifting cultivated soils compared to mixed plantations. Findings of various soil properties, therefore, suggest that shifting cultivation has deteriorating effects on soil environment.

Exogenous Calcium Supplementation Improves Salinity Tolerance in BRRI Dhan28; a Salt-Susceptible High-Yielding Oryza Sativa Cultivar

Tahjib-Ul-Arif,Popy Rani Roy,Abdullah Al Mamun Sohag,Sonya Afrin,Mostafa M Rady,M. Afzal Hossain 한국작물학회 2018 Journal of crop science and biotechnology Vol.21 No.4

Salinity is one of the most brutal abiotic stressors, commencing a great stumbling block in the way of attaining food security in Bangladesh. Cultivation of rice in saline soils can be possible after enhancing its salt tolerance. This study aimed to examine the potential impact of exogenous calcium (3 and 5 mM Ca2+ in CaCl2) on conferring salt tolerance in rice (cv. BRRI dhan28). At the germination stage, Ca2+-primed seeds were grown under 100 mM NaCl stress conditions for nine days. At the seedling stage, rice seedlings were grown in a sandponic culture with Hoagland′s nutrient solution amended or not amended with 100 mM NaCl for 20 days with or without Ca2+ supplementation. Our results revealed that NaCl-stressed rice plants showed highly compromised germination indices and growth parameters, which could be attributed to reduced shoot and root growth, decreased photosynthetic pigments, increased H2O2 accumulation, and elevated levels of lipid peroxidation measured as malondialdehyde (MDA). On the other hand, exogenous Ca2+ application noticeably improved germination indices, growth and biomass-related parameters under salt stress. Ca2+-treated salt-stressed plants displayed amplified chlorophyll content, as well as suppressed the accumulation of H2O2, contributing to oxidative damage protection. Ca2+ supplementation for salt-stressed rice seedlings elevated relative water content without increasing excess proline, indicating the role of Ca2+ in maintaining water balance under stressful conditions. Furthermore, exogenous Ca2+ decreased membrane injury under NaCl stress, as mirrored by notably diminished levels of MDA in stressed seedlings. The defensive role of Ca2+ counter to oxidative stress was connected with the elevated activities of antioxidant enzymes such as catalase, ascorbate peroxidase, and peroxidase. In general, the best results in terms of growth at both germination and seedling stages were obtained in response to 3 mM Ca2+ treatment. Finally, Ca2+ supplementation can be an effective practice to cultivate rice in saline soils.

Shifting Cultivation Effects on Soil Environment in Upland Watershed of Bangladesh

Haque, S.M. Sirajul,Gupta, Sanatan Das,Miah, Sohag Institute of Forest Science 2014 Journal of Forest Science Vol.30 No.2

This research reports the effects of shifting cultivation on soil environment collecting samples from 0-5 cm soil depth from five locations viz. at Burburichhara, Maichchari, Longadu, Sukurchhari and Muralipara in Rangamati district of Chittagong Hill Tracts (CHTs). Soil analyses showed that fungal and bacterial population, microbial respiration and active microbial biomass, maximum water holding capacity, conductivity and moisture contents were significantly (at least $p{\leq}0.05$) lower in shifting cultivated soil compared to adjacent mixed tree plantations at all the sites. On an average in soils of 5 different shifting cultivated lands fungal population was $1.33{\times}10^5$ CFU/g dry soil and bacterial population $1.80{\times}10^7$ CFU/g dry soil and in mixed plantations fungal population was $1.70{\times}10^5$ and bacterial population $2.51{\times}10^7$ CFU/g dry soil. Organic matter and exchangeable Ca and Mg contents were significantly (at least $p{\leq}0.05$) lower and bulk density significantly (at least $p{\leq}0.05$) higher in shifting cultivated land in most of the locations compared to adjacent mixed tree plantations. Ratios of microbial respiration and organic carbon as well as active microbial biomass and organic carbon were distinctly lower and pH higher at 3 locations in shifting cultivated soils compared to mixed plantations. Findings of various soil properties, therefore, suggest that shifting cultivation has deteriorating effects on soil environment.