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      • KCI등재

        은행나무의 잎끝마름병에 미치는 SO2 의 영향

        이두형,배공영,박소홍,강연지 한국환경농학회 1999 한국환경농학회지 Vol.18 No.2

        대기오염과 병충해발생과의 관계를 규명하고자 은행나무에 SO₂가스를 처리한 후, 잎끝마름병균을 접종하여 식물의 생리·생화학적인 변화를 조사하였다. 0.1㎕/ℓ의 SO₂가스를 하루 8시간씩 7일간 은행나무에 처리한 결과 Chlorosis등의 가시피해는 나타나지 않았으나, 광합성이 대조구에 비해 40%가량 감소되고, CO₂이용효율과 수분이용효율이 감소되는 현상을 보였다. 가스처리 후 병원균을 상처접종시키고 42일 뒤 SI와 SFI의 발병도를 조사한 결과 SI가 SFI에 비해 3배 가량 빠르게 병이 진전되어 있었다. 병원균의 먹이가 되는 당의 함량은 대조구, SFI, SI간에 유의성을 보일 만큼의 차이는 보이지 않았으나, 광합성은 SI가 SFI에 비해 11%가량 저하되었다. 광합성이 저하되었음에도 불구하고 당의 함량이 유지되었으므로 탄소 고정관계를 알아본 결과 CO₂ 이용효율이 저하되지 않았음을 알 수 있었다. 이와 함께 수분이용효율이 SI에서 SFI에 비해 13.2% 증가되었다. 이상의 결과를 종합해 보면, 이온유출량 등으로 보아 SO₂가스처리로 인해 식물이 연약해져 병원균에 대한 저항력이 낮아졌고, 수분이용효율의 증가로 인해 탄소 고정이 활발하게 이루어짐으로써 당이 원활히 합성되는 한편 내부적인 변화로 인해 합성된 당의 전류가 억제되어 잎에 당이 축적되었기 때문에 SI의 발병도가 훨씬 높았던 것으로 생각된다. To examine the relationship between air pollution and occurrence of disease in plants, we investigated the alteration of physiology and biochemistry of Ginkgo biloba by inoculating with Coniothyrium sp. and fumigating with 0.1㎕/ℓSO_(-2) Visual damage did not appear but photosynthesis, CO₂use efficiency(CUE) and water use efficiency(WUE) were reduced when G. biloba was exposed to SO₂for 7days (8 hours a day). When inoculated with Coniothyrium sp., the seventies of damage in G. biloba showed a threefold difference between SO₂-treatment (SI) and SO₂-free treatment (SFI) at day 42 from initial inoculation. Little difference was observed in sugar contents that may be used pathogens feed, among control, SFI and SI. In spite of the reduction in photosynthetic rate, sugar contents and CUE were maintained. WUE was enhanced 13% more at SI than SFI. The CO₂fixation boosted because of enhanced WUE, and thus sugar synthesis was not affected. In addition, sugar transport seems to be retarded for some internal alteration. Consequently, the severity of SI was more serious than that of SFI because Coniothyrium sp. easily invades into the physical texture of G. biloba weakened by SO₂fumigation and because sugar was accumulated in leaves of G. biloba.

      • 방광 크롬친화세포종과 동반된 배뇨후 벼락두통

        하윤석,강성진,허소영,이지현,김민정,김종국,김광수 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.1

        Thunderclap headache is a hyperacute, severe headache that is so named because the pain strikes suddenly and severely, and is sometimes a sign of a medical emergency. We report a case of pheochromocytoma in the urinary bladder in a 48-year-old woman who presented with recurrent thunderclap headache after voiding and exercise. So we think thunderclap headache during or immediately after micturition may be an important diagnostic clue of bladder pheochromocytoma.

      • KCI등재후보

        Perspectives of Integrative Cancer Genomics in Next Generation Sequencing Era

        Kwon, So-Mee,Cho, Hyun-Woo,Choi, Ji-Hye,Jee, Byul-A,Jo, Yun-A,Woo, Hyun-Goo Korea Genome Organization 2012 Genomics & informatics Vol.10 No.2

        The explosive development of genomics technologies including microarrays and next generation sequencing (NGS) has provided comprehensive maps of cancer genomes, including the expression of mRNAs and microRNAs, DNA copy numbers, sequence variations, and epigenetic changes. These genome-wide profiles of the genetic aberrations could reveal the candidates for diagnostic and/or prognostic biomarkers as well as mechanistic insights into tumor development and progression. Recent efforts to establish the huge cancer genome compendium and integrative omics analyses, so-called "integromics", have extended our understanding on the cancer genome, showing its daunting complexity and heterogeneity. However, the challenges of the structured integration, sharing, and interpretation of the big omics data still remain to be resolved. Here, we review several issues raised in cancer omics data analysis, including NGS, focusing particularly on the study design and analysis strategies. This might be helpful to understand the current trends and strategies of the rapidly evolving cancer genomics research.

      • KCI등재

        Preliminary Guidelines for the Clinical Evaluation and Management of Long COVID

        Kim Yoonjung,Kim Seong Eun,Kim Tark,Yun Ki Wook,Lee So Hee,Lee Eunjung,Seo Jun-Won,Jung Young Hee,Chong Yong Pil 대한감염학회 2022 Infection and Chemotherapy Vol.54 No.3

        Long-lasting coronavirus disease 2019 (COVID-19) symptoms beyond 12 weeks, the so-called ‘long COVID’ have been increasingly reported worldwide. Long COVID can be manifested in various forms, and there is an increasing demand for proper assessment and management. However, it is challenging when trying to determine the best-practice standards of care based on the current evidence because there is no internationally agreed clinical definition or clear treatment pathway. Therefore, the present guidelines have been drafted to provide advice on diagnosis and management based on the latest updated available evidence and the consensus of expert opinion. So far, no standard test and drug treatment can be strongly recommended for patients with long COVID because of a lack of evidence. The present guidelines provide advice based on 12 key questions, including appropriate interventions for long COVID that can be used in clinical practice. Continuous careful observation and studies related to long COVID are needed for the long-term impact of COVID-19 and proper management for long COVID to be determined.

      • KCI등재

        화재조사현장 호흡가스 유해물질 분석 기초연구

        한동훈(Dong-Hun Han),최신웅(Sin-Woong Choi),이소연(So Yun Lee) 한국화재소방학회 2020 한국화재소방학회논문지 Vol.34 No.6

        화재현장에서는 많은 유해물질들이 생성되어 배출된다. 실제화재현장에서 화재진압대원들은 공기호흡기를 착용하지만 그 이외의 임무(화재조사, 현장지휘 등)로 활동하는 현장대원들은 공기호흡기를 착용하지 못하는 상황이므로현장에서 다양한 유해물질에 노출되고 있는 실정이다. 본 연구에서는 호흡보호가 상대적으로 힘든 화재조사현장에한하여 유해가스 7종을 다중가스검출기를 사용하여 측정·분석하였다. 현직 화재조사관 6명의 도움을 받아 실제 51곳의 조사현장에서 직접 유해가스 농도 데이터를 수집하였다. 아울러 3 곳의 재현실험 현장에서도 시간에 따른 유해가스의 농도를 측정하였다. 화재조사현장에서 측정한 유해가스 농도의 최대값이 허용한계치(Threshold limit value,TLV) 중 단시간노출한계(Short-term exposure limits, STEL)를 초과한 건수는 SO2는 8건, HCHO는 29건, NO2는 1건,HCN은 13건, CO는 2건이었다. 재현실험의 경우는 화재진화 후 1 h 30 min이 경과 되면 대부분의 유해가스 최고농도는STEL기준 이하가 되었다. 따라서 화재조사관의 경우 이에 맞는 호흡보호구를 착용하고 그에 대한 관리가 요구된다. Various types of hazardous substances are generated at fire scenes. Firefighters usually use the self-contained breathingapparatus (SCBA) during firefighting; however, SCBA is very inconvenient to use in other works (e.g., fire investigation andfire scene commands). Therefore, firefighters can be exposed to numerous chemicals. In this study, concentrations ofhazardous gases were measured by utilizing gas analyzers with seven sensors during fire investigations. Six fire investigatorsmeasured the concentrations of hazardous gases directly as they worked. This included capturing the maximum concentrationsof SO2 at seven places, HCHO at 29 places, NO2 at one place, HCN at 13 places, and CO at two places where theconcentration exceeded the short-term exposure limit (STEL). When reconstruction experiments were performed, themaximum allowable concentrations for most hazardous chemicals fell below the STEL approximately 90 min after the fireoccurrence. Therefore, we determined that fire investigators should wear proper respiratory protective equipment when working.

      • KCI등재

        HPLP와 사상체질설문(四象體質說問)을 이용(利用)한 근로자(勤勞者)들의 건강상태(健康狀態) 평가(評價)

        최문일,이은경,권소희,고광재,서병윤,정재열,장두섭,송용선,이기남,Choi Mun-Il,Lee Eun-Kyoung,Kwon So-Hee,Ko Kwang-Jae,Seo Byeong-Yun,Jeoung Jae-Yeal,Jahng Doo-Sub,Song Yung-Sun,Lee Ki-Nam 대한예방한의학회 2001 대한예방한의학회지 Vol.5 No.1

        개인의 건강증진사업을 진행하기 위해서는 건강에 긍정적인 영향을 미치는 생활양식과 생활양식에 영향을 미치는 요인에 대한 역학적 조사가 필요하며 이는 연령집단별로 건강위험인자나 생활양식 및 건강실천행위 등이 모두 다르게 나타나기 때문이다. 체질에 따른 생활양식 등의 차이를 규명하는 것은 체질의학이 예방서비스의 일환으로 적용될 수 있는 기초자료를 제공하는 데 큰 역할을 할 뿐 아니라 체질의학을 현대화하는 데에도 기여할 것으로 사고된다. 이에 본 연구에서는 각 체질을 분석하고 체질별 건강증진 생활양식 실천정도를 파악한 결과 몇 가지 결과를 얻었기에 보고하는 바이다. 1. 연구대상자 중 태음인(太陰人)은 43.7%였고 소음인(少陰人)은 33.6%였으며, 소양인(少陽人)은 22.7%로 나타났다. 2. 연구대상자의 자아실현, 건강책임, 운동, 영양, 대인관계, 스트레스 관리를 포함한 건강증진 생활양식의 총 평균은 138.9이고 총 평점은 2.62이었다. 각 영역별 평점은 대인관계 2.94, 자아실현 2.86, 스트레스관리 2.71, 영양상태 2.68, 건강책임 2.37, 운동영역 2.21의 순으로 대인관계가 가장 높고 운동영역이 가장 낮았다. 3. 건강증진 생활양식 전체영역과의 관계를 보면 여성의 경우와 연령이 높을수록 건강증진 생활양식 실천정도가 높게 나타났다. 건강증진 생활양식 각 영역과의 관계를 보면 성별에서 보면 건강책임영역과 영양영역, 스트레스관리 영역에서 여자가 더 높은 실행정도를 보였고 운동영역에서 남자가 더 높은 실행정도를 보였다(P<0.05). 연령에서는 건강책임영역에서는 30대가, 영양영역과 스트레스관리영역에서는 50대가 가장 높은 실행정도를 보였다(p<0.05). 결혼상태에 따라서는 영양의 영역에서만 기혼자가 유의하게 실행정도가 높게 나타났다(P<0.05). 4. 건강증진 생활양식 각 영역과 사회경제적 특성과의 차이를 보면 월수입에서는 대인관계영역에서만 월수입이 100만원 미만이 가장 높게 나타났고(P<0.05), 교육수준별로는 자아실현영역에서만 교육수준이 높을수록 이행정도가 높게 나타났으나(P<0.05) 나머지 영역에서는 유의한 차이가 나타나지 않았다. 5. 대인관계영역을 제외한 모든 영역에서 태음인(太陰人)의 건강증진 생활양식의 실천정도가 가장 높았으며 자아실현영역에서는 소양인(少陽人)과 거의 비슷했다. 소음인(少陰人)은 건강책임 영역을 제외하고는 모든 영역에서 실천정도가 가장 낮은 것으로 나타났고 건강책임은 태음인(太陰人), 소음인(少陰人), 소양인(少陽人)의 순서로, 대인관계 영역에서는 소음인(少陰人), 태음인(太陰人), 소양인(少陽人)의 순으로 실천정도가 높음을 알 수 있다. Overview: The purpose of this study was to evaluate the determinants on the correlation between constitution and health promoting lifestyle profile on the workers. Also, the questionnaire on the HPLP (health promoting lifestyle profile) of Walker(1987) and Sa-sang constitution of Lee(l894) were utilized Methods: Data from a representative sample of 652 workers were analyzed Pearson's chi-square test analysis was utilized to test the explanatory causal model and to determine the direct and indirect effects of independent variables on quality of life. Results: Constitutional distribution among exposed group, were Tae-eum In(43.7%), So-eum In(33.6%), and So-yang In(22.7%). The degree of the subjects practicing health promoting lifestyle, on a scale of 1 to 4, is an average of 2.62, personal relations 2.94, self-realization 2.86, stress management 2.71, nutrition 2.68, responsibility for health 2.37, and exercise 2.21, with personal relations earning the highest points and exercise the lowest As for factors influencing health promoting lifestyle, there is significant difference between sex and age. That is female and higher age. On the difference between constitution and health promoting lifestyle, Tae-eum In is the highest all area except personal relations. So-eum In is the lowest all area except responsibility for health. Conclusions: Tae-eum In totally do health promoting lifestyle well but So-eum In relatively not. On the Study we used the HPLP(health promoting lifestyle profile) on the premise that each person's daily life, the attitude and the practice level to the health have an influence on the health. So in the constitution there is a little differences in the consideration and the practice level and health condition will be different. On this study we finish up by knowing about the health promoting lifestyle. But on next time we will have to go on studying about the sign and the comparison with the result of western and oriental medical health examination to the each constitution on carrying out continuously oriental medical health examination.

      • KCI등재

        Chemical Properties and Nutrient Loadings of Rainwater during Farming Season

        Min-Kyeong Kim,Seong-Chang Hong,Jong-Sik Lee,Goo-Buk Jung,Soon-Ik Kwon,Mi-Jin Chae,Sun-Gang Yun,Kyu-Ho So 한국토양비료학회 2013 한국토양비료학회지 Vol.46 No.5

        Recently, special attention has been given to acid rain and its problem to environment such as acid precipitation and air pollution in East Asia. In the present study, rainwater samples were collected from Apr to Nov in 2012. The samples were chemically characterized for the assessment of emission sources. Suwon and Yeoju regions, typical agricultural areas in South Korea, were chosen for study sites. Ion composition and cation-affected neutralization were determined to evaluate the contribution of cations to the acidity of rainwater. Ion and electrical conductivity between the measured and the estimated showed high correlation. The cations observed in Suwon and Yeoju were Na<SUP>+</SUP> > NH4<SUP>+</SUP> > K<SUP>+</SUP> > Ca<SUP>2+</SUP> > Mg<SUP>2+</SUP> > H<SUP>+</SUP> and Na<SUP>+</SUP> > K<SUP>+</SUP> > NH4<SUP>+</SUP> > Ca<SUP>2+</SUP> > Mg<SUP>2+</SUP> = H<SUP>+</SUP>, respectively. The anions of all sites were SO4<SUP>2-</SUP> > NO3- > Cl<SUP>-</SUP>. While the amounts of sulfate, one of the major dissolved components of rainwater, were 77.6 and 75.6 ueq L<SUP>-1</SUP> in Suwon and Yeoju, the ones of NSS-SO4<SUP>2-</SUP> (Non-Sea Salt sulfate) were 83 and 82% in Suwon and Yeoju, respectively. The comparison of observed pH values (pHobs) with the theoretical pH values (pHthe) showed that the neutralization of rain water considerably went along during the study periods. The highest amounts of rainfall throughout the year in Suwon and Yeoju were 572.3 and 484.6 mm in July, and its corresponding nitrogen loadings in Suwon and Yeoju were 5.28 and 3.50 kg ha-1, respectively. The major ion contents for crop growth with SO4<SUP>2-</SUP>, Ca<SUP>2+</SUP>, K<SUP>+</SUP> and Mg<SUP>2+</SUP> were 51.7, 5.2, 11.8 and 1.8 kg ha<SUP>-1</SUP> in Suwon and 34.2, 4.0, 4.2 and 1.1 kg ha<SUP>-1</SUP> in Yeoju.

      • 복강경하 질식 자궁적출술 30예의 임상적 고찰 : A Review of 30 Cases

        윤병일,김소정,정두용,김수녕,손인숙,이지영 건국대학교 의과학연구소 2003 건국의과학학술지 Vol.13 No.-

        Hysterectomy is the most common gynecologic operation. Traditionally, hysterectomy was performed either through an abdominal approach or through a vaginal approach. Recently, laparoscopic hysterectomy is quite often tried. To evaluate the effectiveness and value of LA VH(Laparoscopy Assisted Vaginal Hysterectomy), and to evaluate the possibility whether to rep;ace abdominal hysterectomy to LAVH, we analyzed our clinical cases. This clinical study is a retrospective review of 30 cases of LAVH from May 2002 to February 2003 at the department of Obstetrics and Gynecology, Chung- Ju hospital, Konkuk University. We evaluated age, parity, previous abdominal operations, indications of hysterectomy, combined operation, operating time, hemoglobin change, weight of uterus, hospital stay and postoperativeThe average operating time was 146 ± 42 minutes, the uterine weight was 239 ± 126 grams, and the mean postoperative hemoglobin loss was 1.7 ± 1.4 g/dl. The most common pathologic finding was myoma uteri(37%), and the second most pathologic finding was adenomyosis(20%) and myoma uteri with adenomyosis (20%). Serious complications were not appeared. LAVH provides a shorter hospital stay, quicker recovery, and the acceptable complication rate except incerased operating time than abdominal hysterectomy. This study suggests that LAVH appears more useful than TAH(Total Abdominal Hysterectomy) and could replace abdominal hysterectomy.

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