원거리 플라즈마 화학증착법으로 증착된 이산화규소박막의 물성

박영배,강진규,이시우,Park, Yeong-Bae,Gang, Jin-Gyu,Lee, Si-U 한국재료학회 1995 한국재료학회지 Vol.5 No.6

원거리 플라즈마 화학증착법을 이용하여 저온에서 이산화규소박막을 제조하였다. 본 연구 에서는 공정변수인 기판의 온도, 반응기체의 조성 및 분압과 플라즈마 전력에 따른 산화막의 재료적인 물성을 평가하였다. XPS결과에서 산화막은 양론비(O/Si=2)보다 약간 적어 실리콘이 많이 함유된 막으로 나타났다. 이 경우 굴절율과 ESR분석에 의해 미결합된 실리콘의 양이 증가함을 알 수 있었다. SIMS분석에 의해 미량의 질소성분이 계면에 존재하는 것과 실리콘 미결함을 관찰하였다. FT-IR로부터 막내 수소량을 정량화하였으며 결합각 분포는 20$0^{\circ}C$이상에서 열산화막과 비슷한 값을 얻었다. 하지만 열산화막에 비해 높은 식각율을 보여 계면 스트레스에 의해 막내의 결합력이 약해진 것으로 생각된다. Silicon oxide thin films were deposited by remote plasma chemical vapor deposition (RPCYD). The effect of the operating variables, such as plasma power, deposition temperature and partial pressure of reactant on the material Properties of the silicon oxide film was investigated. By XPS, it was found out that the film was suboxide (O/Si<2) and small amount of nitrogen due to the plasma excitation was accumulated at the Si/SiO$_2$interface. The amount of dangling bonds at the Si/SiO$_2$interfaces were measured by ESR and the concentration of hydrogen bond was obtained by SIMS and FT-IR. The bond angle distribution(d$\theta$/$\theta$) was shown to be similiar to thermal oxide above 20$0^{\circ}C$ but the etch rate was higher than that of the thermal oxides due to the structural difference and the stress between silicon substrate and silicon oxide film.

지방산, 지방 알코올 및 프로필렌글리콜이 클렌부테롤의 경피투과에 미치는 영향

이영대,권기철,정시영,이종달,용철순 영남대학교 약품개발연구소 2000 영남대학교 약품개발연구소 연구업적집 Vol.10 No.-

Clenbuterol, a selective β_(2)-adrenergic receptor stimulant, has been introduced as a potent bronchodilator for patients with bronchial asthma, chronic bronchitis and pulmonary emphysema. For the purpose of developing a transdermal preparation for clenbuterol, we attempted to select an optimal solvent system and permeation enhancer among fatty acids and fatty alcohols which are known to accelerate the penetration of various drugs in permeation experiments using hairless mouse skin and Franz diffusion cell. Apparent partition coefficient of clenbuterol was increased as pH of buffer solution was increased and solubility of clenbuterol was increased as the percent of propylene glycol(PG) in buffer solution(pH10) was increased. Permeability of clenbuterol from different buffer(pH 10)/PG solvent mixtures was decreased as the percent of PG in pH 10 buffer solution was increased and among the various enhancers studied, lauryl alcohol was found to be the most effective enhancer, increasing the permeability of clenbuterol approximately 76-fold compared with control. Lauryl alcobol(0-2%) enhanced the permeability of clenbuterol concentration-dependently. In this study, the optimal solvent system for the penetration of clenbuterol was found to be 50/50 buffer(pH 10)/PG solvent mixture containing 2% lauryl alcohol.

間伐이 편백나무의 直徑成長에 미치는 影響

權泳徹,金是璟 진주산업대학교 1977 論文集 Vol.15 No.-

間伐이 편백나무의 直徑成長에 미치는 影響을 究明하기 위해서 南海郡 二東面 所在 25㏊의 편백나무 林分中 北向林分(A)에서 間伐區(A_1)와 無間伐區(A_2)를, 또한 西向林分(B)에서 間伐區(B_1)와 無間伐區(B_2)를 각각 0.1㏊씩의 標準地를 選定하고, 이 標準地의 林木을 生長錐를 使用해서 胸高部位의 南北 두 方向에서 Core를 採取하였다. 이 Core의 各 年輪폭을 測定하여 直徑成長의 實態를 考察한 바 이를 要約하면 다음과 같다. (1) 北向林分의 間伐區는 無間伐區에 比해서, 또한 西向林分의 間伐區는 無間伐區에 比해서 매우 넓은 年輪폭을 形成하였으며 한 年輪폭의 平均斷面積과 年輪폭의 累加面積은 2倍 以上의 成長을 하여 間伐의 效果를 뚜렷하게 나타내었다. (2) 西向林分의 間伐區 및 無間伐구는 北向林分의 間伐구 및 無間伐區에 比해서 다소 좋은 성장을 나타내고 있으며 이는 立木度, 方位, 傾斜度, 土深, 標高 등 立地條件의 差異로서 이루어진 것이 아닌가 생각된다. This study was carried out to determine the effect of thinning on the diameter growth of hinoki-cypress (Chamaecyparis obtusa Endl.) Each hinoki-cypress stand was seleced from the 25 ㏊. stand located at Leedong-Myeun Namhae-Goon. Each 0.1 ㏊. stand was designed by the thinning plot (A1) and the non thinning plot (A2) on the northern stand (A), and the thinning plot (B1) and non thinning plot (B2) on the western stand (B). This sample plot of the standing trees were taken the core of the breast hight (1.2m. above the ground) by using the increment borer on both the southern and northern directions. The results obtained were as follows : 1. On both western stand and northern stand, the annual ring width in thinned trees was wider than that in the unthinned. Each average cross section area and the annual ring area summed in thinned trees were more than twice larger than those in the unthinned. There was a significant effect of the thinning on diameter growth. 2. Growth rate of both thinned plot and the unthinned plot of the western stand was better than that of both thinned plot and unthinned plot on the northern stand respectively. It was assumed that this tendency would be caused by the differences of soil site conditions such as density of trees, bearing, degree of slope, soil depth, and altitude etc.

소나무의 높이별 年輪幅에 나타나는 生長의 패턴에 關한 硏究

權泳徹,金是璟 진주산업대학교 1983 論文集 Vol.21 No.-

本硏究는 소나무를 資料로 하여 林木의 높이別 年輪幅에 나타나는 生長의 패턴을 解析하고 또한 林木의 密度가 年輪生長에 어떤 影響을 미치는가를 調査한 것이다. 그 結果를 要約하면 다음과 같다. 1. 斜面方向系列의 年輪幅生長 패턴은 樹冠의 葉量과 樹幹內에 存在하는 營養句配와 密接한 關係가 있는 것으로 調査되었다. 2. 垂直方向系列은 年輪幅의 變化가 不規則하여 一定한 生長패턴이 없는 것 같으며, 이는 外部環境要因이 反映된 것으로 생각되며, 年輪幅增減現象으로 보아 林木의 密度에 따라 樹冠競爭의 差가 4年 程度있는 것으로 調査되었다. 3. 水平方向系列은 斜面方向과 垂直方向列의 性質을 함께 가지며, 根源部(X)와 胸高部(Y)의 年輪幅增減現象을 보면 林木의 密度에 따라서 樹冠競爭의 差가 垂直方向系列과 같이 4年程度있는 것으로 調査되었다. 4. 垂直方向과 水平方向系列의 年輪幅增減現象을 보면 密生林(A)은 10年生때, 疎生林(B)은 14年生때 間伐로서 林木의 密度調節이 要求되었다. These studies were carried out to know the growth patterns appearing in annual ring width at different heights and the influence of stand density on growth in annual ring of Pinus densiflora S. et. Z. The results are summarized as follows; 1. The coefficient correlations among the growth patterns appearing in annual ring width of oblique sequence, the volume of leaves in crown and the nutrition slope in stem showed to be high significant by stand. 2. The vertical sequence did not have a peculiar growth pattern owing to be irregular in the variation of annual ring width, and it should be affect on the variation of growth by environment factors, therefore I conclude that the difference of the crown conflict of different stand density was recognized to be period of 4 years by the tendency of the increase and decrease in annual ring width. 3. Horizontal sequence contained both its quality of oblique sequence and vertical sequence, and also the difference of the crown conflict of different stand density was recognized to be the period of 4 years, as it was shown the tendency of the increase and decrease in annual ring width of the part of stump and the position of breast height. 4. The proper thinning time was showed to be the period of 10 years in case of closely spaced stand and the period of 14 years in case of sparsely spaced stand by the tendency of the increase and decrease in annual ring width of vertical sequence and horizontal sequence, and then we should be control the crown density.

PCR과 SDS-PAGE를 이용한 Bifidobacteria의 동정

박시홍,송희성,이지연,김해영 경희대학교식량자원개발연구소 2005 硏究論文集 Vol.24 No.-

SDS-PAGE를 이용한 단백질 패턴의 분석결과, 같은 종의 Bifidobacterium은 동일한 단백질 패턴을 보이며, 다른 종의 Bifidobacterium은 서로 다른 패턴을 보이고 있는 것을 확인하였다. 따라서 SDS-PAGE를 이용한 whole cell protein 패턴 분석으로 Bifidobacterium을 간편하고 빠르게 동정할 수 있는 가능성을 보였다. DNA homology 98% 이상으로 PCR에 의해 동정에 어려움이 많았던 B. catenulatum, B. Pseudocatenulatum group, B. animalis을 SDS-PAGE로 확인한 결과, B. catenulatum과 B. pseudocatenulatum, B. animalis는 뚜렷한 단백질 패턴의 차이를 보임으로써 구별이 가능했다. PCR 수행 시 primer제작은 기존에 보고된 것과 NCBI blast program을 통하여 제작을 하였으며, 그 결과 B. longum, B. bifidum, B. adolescentis 3종류의 종에서만 특이적으로 band가 나타나는 것을 확인할 수가 있었다. 본 실험에서는 SDS-PAGE와 PCR을 이용한 균주 동정법으로 신속하고 정확하게 Bifidobacterium을 탐색할 수 있었으며, 발효유 제조나 의약품 제조 등 산업적으로 이용 될 수 있을 것이다 (Mitsuoka, 1984). Bifidobacterium is a Gram-positive obligate anaerobic bacterium which is able to change cellular shape by nutritional conditions and dominant species in intestinal microflora of human. In order to identify Bifidobacteria spp. in human intestine, PCR and SDS-PAGE of whole cell proteins were used. Species-specific primer sets based on the 16S rRNA, 16S-23S intergenic spacer and heat shock protein genes of three Bifidobacteria spp. were constructed using NCBI blast program (Bifidobacteria adolescentis, B. longum and B. bifidum). PCR products using each primer sets showed the same sizes of expected target genes. From the SDS-PAGE of whole cell proteins in bifidobacteria, profiles of SDS-PAGE between 13 type strains showed distinct differences. These methods will be useful for monitoring and evaluating Bifidobacteria spp. in human intestine microbial population.

生長錐에 의한 편백나무 直徑生長의 豫測에 關한 硏究

金是璟,權泳徹 진주산업대학교 1977 論文集 Vol.15 No.-

This study is carried out to investigate the prediction of the growth of diameter by the increment borer in hinoki cypress with an accurate formula. The data of this study are the data of 40 from the core in position of breast height of 20 pieces of hinoky cypress using the increment borer. The results are summarized as follows. 1. Let Y be the growth of semi-diameter for 5 years of the past from a certain moment, X be the growth of semi-diameter for 5 years before Y, and Z be the growth of semi-diameter for 5 years of the future from the moment, then we can obtain the following formula by the method of least squares using the data of 40 above mentioned, Z ㎝=0.1534+0.6754 Y ㎝…………(1) 2. As there is no rationality for current annual increment of trees between the formula(1) regarding as Y=O is Z=0.1534, therefore we can obtain the next formula using the method of least squares by formula of logarithm. log Z=0.0547+0.8816 log Y…………(2) 3. The prediction of the growth of diameter for comming 5 years (Z) regarding as equivalent to the growth of past 5 years (Y) is not correct. Using the data we can obtain the next formula, Y ㎝=0.0023+0.8041 X ㎝…………(3) and, as there is no significant difference between the formula (1) and (3), we can substitute (3) in place of (1). 4. We can easily obtain the formula (3) by measuring X and Y in the stand under investigation, and we can predict Z by Y of the formula (1) substituting Y by X of the formula (3) with no bias, accordingly it is good example to apply to the formula (2) with Y of the formula (3).

Parkinson's disease에서 [18F]-FP-CIT을 이용한 Brain PET/CT영상의 유용성

강용길 ; 홍시영 김천대학교 2009 김천대학교 논문집 Vol.30 No.-

Neuroreceptors and transporters have an important role in brain function.Parkinson's disease is a common neurodegenerative disorder that is mainly causedby dopaminergic neuron loss in the substantia nigra.Distribution, density, and activity of neuroreceptors and transporters can bevisualized by radiotracers with PET and SPECT.In vivo PET and SPECT imaging of presynaptic dopamine imaing are alreadyapplied to Parkinson's disease and other parkinsonism, and can demonstrate thedopaminergic dysfunction.Dopamine transporter imaging is useful in the diagnosis of Parkinson's diseaseand the most successful technique in the clinical use of neuroreceptor imaging.​Recently, several radiopharmaceuticals including 123I-FP-CIT, 99mTc-TRODATand 18F-FP-CIT for dopamine transporter imaging have been approved for theroutine clinical use in several European countries, Taiwan and Korea, respectively.Therefore, In this paper an overview of Parkinson's disease medicines for diag-nosis and radioactive 18F-FP-CIT using a PET/CT imaging has confirmed theusefulness of the clinical use.

民族主義的 側面에서 본 韓國文學 : 日帝治下의 文學을 中心으로 Especially during the Japanese Rule of Korea

梁重海,金時泰,金永和 제주대학교 1973 논문집 Vol.5 No.-

How national consciousness is reflected in Korean literature during the Japanese rule of Korea can be a matter of our concern, partly because national consciousness and nationalism embedded in literary works were one of our issues of that period, and partly because it is significant to fathom the historical import of such literature and explain its present implications. In this article, main Colonial literary works with deep layers of national consciousness and nationalism in them are looked into in three separate genres:(1) poetry, (2) fiction, (3) criticism. In poetry, national self-esteem and resistance to Japanese imperialism were urged suggestively and metaphorically in the form of expressions peculiar to poetry. In fiction, the first phase of the resistance characterized by negative enlightenment eventually grew into the phase of positive, though suggestive, manifestation and description of the spirit of resistance. In literary criticism, first, most critics analyzed the discord and friction between nationalism and socialism by inquiring into the process through which these two ideologies were introduced into literature and by surveying the scope of literary theories based on the two ideas. Secondly, they tried to find the historical import and the sphere of nationalistic literary theories by analyzing the reflection of such theories in Korean society described in literary works, and by analyzing the contribution of such theories to the formation of spiritual structure of Korean literature. Such literature tells us that literature can not be separated from realities of the times and that it abstracts and reorganizes the notions of the age. In that respect, we can assert that the Koreans under the Japanese rule criticized, denied, and resisted the Colonial age instead of accepting it tolerantly.

방전관용 전극개발 및 특성에 관한 연구

안성환,황동원,최준영,송시준,전용우,박원주,이광식 영남대학교 공업기술연구소 2001 工業技術硏究所論文集 Vol.29 No.1

This paper describes the development of sputtered tungsten electrode for discharge tube by making use of Sputtering method using plasma. The Xe discharge tube was designed and fabricated by using sputtered tungsten electrode, and the ICCD(Intensified Charged Coupled Device) and monochromator were used in order to observe the discharge image distribution and to measure the signal intensity. As a result, the emission light form the electrode was spreaded almost uniformly over a wide wavelength band, and the discharge image distribution and the signal intensity show quite a uniform distribution. The emission light from the Xe discharge tube was peaked at 488[nm] and 648[nm].

혈액 투석 환자에서 중심정맥 협착에 대한 스텐트 삽입술 : Wallstent Placement

임대승,노상필,이유선,정승현,김보영,이정우,강정아,김정희,이민수,정준용,최시완,정진옥,성인환,이강욱,신영태 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

Stenosis of central vein is a common complication arising after percutaneous subclavian vein catheter insertion performed for temporary vascular access in chronic renal failure patients undergoing hemodialysis. There are several treatment methods for the condition like percutaneous angioplasty(PTA), stent insertion, and surgery, but recent trend is toward PTA and stents. Among the patients diagnosed with chronic renal failure from March 1993 to May 2002 and undergoing hemodialysis through AV fistula, the 14 Patients in whom central vein stenosis arose were selected for the study. A total of 28 percutaneous interventions(5 PTA and 23 stent placement) were performed, and restenosis rate and the time taken till the restenosis in de novo lesions and instant lesions were compared. All 28 cases were operated successfully. The 14 cases that received both anigioplasty and stent placement initially. (de novo lesion : 14 cases), Among the 10 cases with de novo lesion that followed up more than 1 year, 3 cases are currently undergoing hemodialysis without restenosis, and the remaining 7 cases have recurred stenosis with the mean time to restenosis of 10.9 months. In the 7 cases in whom stenosis recurred, 11 interventions were done(instent lesion: 11 cases). 4 of these were using only ballon angioplasty with 100% restenosis rate and the mean time of 3 months until restenosis. The remaining 7 cases were using both balloon angioplasty and stent placement, also with 100% restenosis rate but with the mean time of 12 months until restenosis, which was later than the group receiving only balloon angioplasty. In treating the patients with central vein stenosis, stent placement seems to be more advantageous over PTA in terms of restenosis rate and the mean duration of patency. In the case of instent lesion, inserting the stent for the second time after stenosis recurred lengthened the duration of patency compared to performing balloon angioplasty alone.