장방형 밀폐공간내의 유체유동 및 전열특성에 관한 수치해석

서이수,유신오,전성모 東亞大學校 大學院 1997 大學院論文集 Vol.22 No.-

In this paper were investigated the numerical study of fluid flow in which the difference analysis connected the natural convection and mixed convection within enclosed condition. The cell boundaries arrangement for these calculations, uniformally divided as 44×44 when heated the bottom to muliply the length and height, and was in proportion 4 : 1 to the length and height when heated the left side to muliply 88×11. According to the repeat calculation of time division were obtained the temperature distribution, the velocity distribution, the isotherms distribution, & streamlines distribution in which the natural convection was altered Pr=0.71, Gr=10?. Gr=5×10?, Gr=10? and the mixed convection was changed as Pr=0.71, Re=100, Re=1000. For the numerical study on the heat transfer and fluid flow, the following consequence have calculated in proportion 4 : 1 to the length and hieght of rectangular enclosure with the number of Pr=0.71, the number of Re=100, 1000, the number of Gr=10?, 5×10?, 10?.

新農村建設(定住生活圈開發)을 위한 理論的 考察 및 開發需要調査

金鴻允,李弘柱,鄭禮杓,全禹亭,趙興洙,李信昊,全榮吉 안성산업대학교 1992 論文集 Vol.24 No.-

Rural of Koreas has rapidly changed through the process of industrialization and urbanization. During past 30 years, development differences between urban and rural, metroplitan area and area derived from a highly economic growth, bring about dual specialization that deepens overpopulation and sparsity. Therefore, with a new concern about rural, necessity of rural development policy that developes a settlement and life area for settlement for ensuing stablized settlement and living activity of rural people, has been drived step by step. For rural welfare establishment that is settled and good hereafter, this study aims at attempting a theoretical approach about the way of development for rural settlement as a new rural development strategy through examination of today's rural reality, under assumption that rural people must be able to obtain stable jobs and to be pleasant without leaving rural area, and rural settlement to be able to enjoy urban advantages must be realized. Therefore, items that must be obtained basically rural area to be a human settlement space are equipment connected with a dwelling house, production, consumption, job relaxation, infrastructure connected with transportation or communication network and environment. By the way, the best function of a human settlement space makes a basic pleasant settlement area to be in the middle of that. Then rationalization of land use must be realized as being a best condition for human life around space of a dewelling house. Besides, spacial accessibility about all equipment of inhabitants must be easy. That is, economic distance, social distance and cultural distance as well as spacial distance must be included. Also, those spacial functions must be realized on a basis of suitable enironment for a human settlement life. At the same tiem, the upper area must be connected with the lower area as the system of spacial settlement in settlement space. But truely, as rural people can't satisfy with services of the surrounding rural areas, they desire better city or metroplitan. The these problems bring about inequality between urban and rural. Therefore, here are urgent reasons that must be done rearing of rural central town and rural integrated development of unit area. So, these dys, to correct maldistribution of land use and inequality of settlement space that Korean society faces on, new strategies of rural integrated development for lift area for settlement than gives the meaning. That rural areas become like a place for human settlement life will be able to be chosen in the view of humanism. The say of thinking of rural residents(Jukans-myun, Anseong-gun, Kyeonggi-do) was surveyed in order to develop new rural settlement planning. From the data collected in this survey, rural life-style, view on traditional rural life, agriculture, farming, agri-policy, social attitude, and degree of satifaction of rural life, etc, were analyzed. Firstly, most of rural residents interviewed in this survey have the opinion of not leaving their home village if living conditions improved to a reasonable level in the near future. In decision-making process of village affairs, they want to participate actively and equally. Secondly, in spite of their acceptance of agriculture as a vital sector destined to national security, most of them think that framing should be little of promise. Thirdly, they have the negative attitude to urban-oriented social valued and also to the agricultural policy, while seeking consolation through human and traditional viewing of rural life style. Therefore, in the development of new rural settlement model, idea-making should be directed to the betterment of communal value of village life, stability of rural economy, rationalization of rural life style and enhancement of rural-type happiness.

국내에서 유행하는 HIV의 전파 경로에 따른 Subtype 분포

이주실,남정구,김성순,강춘,최병선,김옥진,박미선,성봉모,서순덕,전수경,변승옥,신영오,조해월 대한감염학회 2001 감염 Vol.33 No.5

Background : Previous data have been reported that subtype B is prevalent in South Korea, but neither the extent nor the proportion of subtypes could be evaluated. This study was designed to analyze the distribution of HIV-1 subtypes, temporal instructions and transmission dynamics between epidemiological groups. Methods : 1,280 Koreans had been diagnosed as HIV seropositive during the period 1985 to 2000. Among them, 134 individuals were selected for this molecular epidemiological study. 134 DNAs were isolated from uncultured or cultured peripheral blood mononuclear cells. V3-V5 (0.7 kb) fragment of HIV-1 env gene was amplified by nested polymerase chain reaction and was sequenced. Results : HIV-1 isolates from thirty-seven homosexuals were all subtype B (100%). On the other hand, 66 isolates from 94 heterosexuals were subtype B (70%) and 28 were non B subtypes (30% : 13 A, 4 C, 2 D, 8 E , 1 G). Only subtype B strains were isolated from 73 males who were infected with HIV inside Korea while 16 B and 20 non B subtype strains were isolated from 36 males who were HIV infected outside of Korea. However, B and non B strains were isolated half and half from females who were infected inside Korea except one. Conclusion : The HIV-1 subtype B strains are prevalent in Korea from the early HIV infection until present in both homo and heterosexuals. Non B strains have been transmitted from men who were infected outside Korea to their spouses and casual partners. So, we need further study to monitor subtype B and non B HIV transmission in epidemiological groups of Korea, (Korean J Infect Dis 33:311∼318, 2001)

Fabrication of three-dimensional porous carbon scaffolds with tunable pore sizes for effective cell confinement

Jeon, Min Soo,Jeon, Yale,Hwang, Jeong Hoon,Heu, Chang Sung,Jin, Sangrak,Shin, Jongoh,Song, Yoseb,Chang Kim, Sun,Cho, Byung-Kwan,Lee, Jung-Kul,Kim, Dong Rip Elsevier 2018 Carbon Vol.130 No.-

<P><B>Abstract</B></P> <P>Here, we demonstrate the fabrication of 3D porous carbon scaffolds with tunable pore sizes that are comparable to the sizes of bacterial cells for their effective confinement. We utilized the sphere template method to fabricate the 3D porous carbon scaffolds with excellent pore arrangements and enlarged interconnected areas among the pores. The proposed 3D porous carbon scaffolds trapped about 40 times higher densities of <I>Escherichia coli</I> DH5α than conventional 3D porous reticulated vitreous carbon (RVC) scaffolds. Moreover, the proposed porous scaffolds effectively restrain the detachment of the attached cells from the scaffolds because of their geometries, thereby maintaining about 75% of the initial cell densities under repeated washing, whereas almost all the cells were washed away from the conventional 3D porous RVC scaffolds. This effective confinement of bacterial cells will assist in significantly improving the performance of cell-based biological applications.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

<i>Uncaria rhynchophylla</i> ameliorates amyloid beta deposition and amyloid beta-mediated pathology in 5XFAD mice

Shin, Soo Jung,Jeong, Yuon,Jeon, Seong Gak,Kim, Sujin,Lee, Seong-kyung,Choi, Hong Seok,Im, Cheong Su,Kim, Seong Hee,Kim, Soo Hwan,Park, Jae Ho,Kim, Jin-il,Kim, Jwa-Jin,Moon, Minho Elsevier 2018 Neurochemistry International Vol.121 No.-

<P><B>Abstract</B></P> <P>One of the pathological hallmarks of Alzheimer's disease (AD) is the abnormal aggregation of amyloid beta (Aβ) peptides. <I>Uncaria rhynchophylla</I> (UR), one of the <I>Uncaria</I> species, has long been used to treat neurodegenerative disease. In particular, it has been reported that UR inhibits aggregation of Aβ <I>in vitro.</I> However, little is known about the histological effects of UR treatment on Aβ pathology in AD animal models. In the present study, we investigated the effect of UR on Aβ aggregation, Aβ-mediated pathologies and adult hippocampal neurogenesis in the brain of 5XFAD mice. First, using the thioflavin T assay and amyloid staining, we demonstrated that UR treatment effectively inhibited Aβ aggregation and accumulation in the cortex and subiculum. Second, immunofluorescence staining showed that administration of UR attenuated gliosis and neurodegeneration in the subiculum and cortex. Third, UR treatment ameliorated impaired adult hippocampal neurogenesis. The present results indicate that UR significantly alleviates Aβ deposition and Aβ-mediated neuropathology in the brain in 5XFAD mice, suggesting the potency of UR as a preventive and therapeutic agent for AD.</P> <P><B>Highlights</B></P> <P> <UL> <LI> <I>Uncaria rhynchophylla</I> (UR) inhibited Aβ aggregation and accumulation. </LI> <LI> UR alleviated neuroinflammation induced by Aβ. </LI> <LI> Treatment of UR relieved synaptic and neuronal loss in AD mice. </LI> <LI> UR attenuated impaired hippocampal neurogenesis induced by Aβ. </LI> </UL> </P>

Borrelia burgdorferi에 대한 단세포군 항체의 생산 및 특성분석

신전수(Jeon-Soo Shin),조상래(Sang-Nae Cho),이정림(Jung-Lim Lee),박선(Sun Park),윤경한(Kyeong-Han Yoon),이재면(Jae-Myun Lee),이미경(Mi-Kyeong Lee),김세종(Se-Jong Kim),김주덕(Joo-Deuk Kim) 大韓微生物學會 1992 大韓微生物學會誌 Vol.27 No.6

보건의료분야 다수준 분석 연구의 체계적 문헌 고찰: 국내 연구동향과 비뚤림 위험 평가를 중심으로

신상수 ( Shin Sang Soo ),우경숙 ( Woo Kyung Sook ),신영전 ( Shin Young-jeon ) 한국보건사회연구원 2015 保健社會硏究 Vol.35 No.4

이 연구는 체계적 문헌고찰을 통해 국내 보건의료분야 다수준 분석의 동향을 파악하고 논문의 질적 평가를 목적으로 비뚤림 위험 평가를 시행하여 향후 보건의료 분야 다수준분석기법의 유용성을 높이는 목적으로 연구를 수행하였다. 2000년 1월 1일부터 2014년 12월 31일까지 국내외 웹 기반 학술 데이터베이스에 출판된 59편의 논문을 분석한 결과는 다음과 같다. 첫째, 통계적 유의성을 보인 지역 변인은 전체의 20.9%로 다소 낮았다. 둘째, 가장 많이 사용된 지역 변인은 사회문화적 특성이었으며, 지역에 대한 평판 관련변인 중 40.7%가 통계적 유의성을 보였다. 셋째, 건강행태·지식·신념 관련 요인 연구가 전체의 34.4%로 다수를 차지하였다. 넷째, 4편의 연구가 개인변인에 의한 연구 결과의 비뚤림 위험 가능성이 나타났다. 지역변인 측면에서는 급내 상관계수 관련정보 미제공(28편, 47.4%), 30개 이하 지역표본 사용(29편, 49.2%), 지역변인 간 상관관계분석 미실시(36편, 69.2%), 지역변인 기초 정보 제공 미흡(15편, 25.4%)으로 인하여 비뚤림위험 가능성이 확인되었다. 신뢰성 높은 자료의 이용, 다양한 지역변수의 활용, 변인간 상관관계를 포함한 비뚤림 위험 방지를 위한 사전 점검, 지역 특성이 건강에 영향을 미치는 기전의 구체화 등의 작업이 이루어진다면 다수준 분석은 질병에 대한 이해와 효과적인 개입수단을 발견하는데 보다 유용한 수단으로 활용될 수 있을 것이다. This study was conducted to identify the status of studies on multilevel analysis concerning Koreans` health, validate the assessment of risk of bias to assess the quality of journals, and provide a basis for practicing multilevel analysis for future public health. We analyzed a total of 59 studies published from January 1, 2000 to December 31, 2014 in domestic and international journal databases. The findings include the following. First, only 20.9% of total had statistical significance. Second, the regional reputation was the most frequently used variable with a statistical significance on health. Third, 34.4% were on health behaviour, knowledge or attitude. Fourth, 4 studies (6.7%) were identified with a potential risk of bias caused by individual variables. There were journals with missing in ICC (28, 47.4%), the use of regional sample under 30 (29, 49.2%), missing in a correlation analysis between regional variables (36, 69.2%), and missing in basic information on region data (15, 25.4%). These would cause the risk of bias. It will be a useful analytical tool to understand the causes of health when executing reliable data, using diverse regional variables, doing pretest to prevent risk of bias such as correlation analysis between regional variables and specifying mechanisms of health affected by regional characteristics.

Rickettsia tsutsugamushi 항체 검출에 있어서 간접 면역형광항체 검사법, 간접 면역과산화수소 항체 검사법과 간접 효소결합 면역흡착 검사법의 비교

신전수(Jeon Soo Shin),조상래(Sang Nae Cho),이미리나(Millina Lee),정윤섭(Yunsop Chong),서일(Il Suh),김주덕(Joo Deuk Kim) 大韓微生物學會 1991 大韓微生物學會誌 Vol.26 No.1

Validity analysis on merged and averaged data using within and between analysis: focus on effect of qualitative social capital on self-rated health

Sang soo Shin,Young-jeon Shin 한국역학회 2016 Epidemiology and Health Vol.38 No.-

OBJECTIVES: With an increasing number of studies highlighting regional social capital (SC) as a determinant of health, many studies are using multi-level analysis with merged and averaged scores of community residents’ survey responses calculated from community SC data. Sufficient examination is required to validate if the merged and averaged data can represent the community. Therefore, this study analyzes the validity of the selected indicators and their applicability in multi-level analysis. METHODS: Within and between analysis (WABA) was performed after creating community variables using merged and averaged data of community residents’ responses from the 2013 Community Health Survey in Korea, using subjective self-rated health assessment as a dependent variable. Further analysis was performed following the model suggested by WABA result. RESULTS: Both E-test results (1) and WABA results (2) revealed that single-level analysis needs to be performed using qualitative SC variable with cluster mean centering. Through single-level multivariate regression analysis, qualitative SC with cluster mean centering showed positive effect on self-rated health (0.054, p<0.001), although there was no substantial difference in comparison to analysis using SC variables without cluster mean centering or multi-level analysis. CONCLUSIONS: As modification in qualitative SC was larger within the community than between communities, we validate that relational analysis of individual self-rated health can be performed within the group, using cluster mean centering. Other tests besides the WABA can be performed in the future to confirm the validity of using community variables and their applicability in multi-level analysis.

자살생각에 영향을 미치는 요인에 관한 다수준 분석

신상수(Shin, Sang-Soo),신영전(Shin, Young-Jeon) 비판과 대안을 위한 사회복지학회 2014 비판사회정책 Vol.- No.45

자살의 예측요인으로 알려진 자살생각에 대한 사회적 관심이 증가하면서 자살생각의 기전을 설명하고자 하는 다양한 시도가 등장하고 있다. 개인을 둘러싼 환경이 개인의 건강에 영향을 준다는 근거가 속속 등장하고 있는 가운데, 이번 연구에서는 2009년 지역사회건강조사 자료를 이용하여 다수준 로지스틱 회귀분석을 이용하여 자살생각에 미치는 개인 요인과 지역 요인을 동시에 고려하여 살펴보았다. 분석 결과, 개인 수준에서는 연령이 증가할수록, 학력이 낮을수록, 이혼·사별·별거 및 미혼이 기혼에 비해, 소득이 감소할수록, 스트레스가 많을 때, 우울할 때, 주관적 건강감이 나쁠 때 자살생각 오즈비가 통계적으로 유의하게 높은 것으로 나타났다. 지역 수준에서는 지역박탈지수와 기초생활보장수급자비율, 재정자주도를 각각 대입하여 분석하였는데, 지역박탈지수와 기초생활수급자 비율이 증가할수록 자살생각의 오즈비가 낮아지는 것으로 나타났으나 지역규모를 구분하여 분석한 결과에서는 군 지역에서만 유의하였다. 이러한 분석 결과를 바탕으로 자살생각 가능성을 완화하고 방지할 수 있는 실천적 함의를 제시하였다. As social interest in suicidal ideation known as a predicting factor of suicide is rising, various attempts are made to explain the mechanism of suicidal ideation. With grounds published for the effects of an environment surrounding an individual on his or her health, this study set out to take into account both personal and neighborhood factors influencing suicidal ideation through multi-level logistic regression analysis based on the Community Health Survey data of 2009. The analysis results show that the odds ratio of suicidal ideation was statistically significantly high at the personal level when they were older, had lower educational backgrounds, were divorced, bereaved, or separated and a single rather than being married, had lower family income, suffered more stress, felt depressed and had a bad subjective sense of health. At the neighborhood level, analysis was conducted by introducing the regional deprivation index, the rate of National Fundamental Livelihood Security recipients, and financial autonomy rate. As a result, the odds ratio of suicidal ideation dropped as the regional deprivation index and rate of National Fundamental Livelihood Security recipients rose. When the local scale was taken into account during analysis, it turned out that only rural areas generated significant results. Suggestions addressed the strategies to pacify and prevent suicidal ideation among community residence.