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Synthesis of New Diselenide Compounds as Anti-Inflammatory Agents
Shen, Liulan,Shin, Kyung-Min,Lee, Kyung-Tae,Jeong, Jin-Hyun The Pharmaceutical Society of Korea 2004 Archives of Pharmacal Research Vol.27 No.8
Many diselenide compounds are used as antioxidants, enzyme inhibitors and cytokine induc-ers. Three new diselenide compounds, bis-(2-hydroxyphenyl) diselenide, bis-(3-hydroxyphe-nyl) diselenide and bis-(4-hydroxyphenyl) diselenide were designed and synthesized as anti-inflammatory agent. All of them were found to have strong in vitro activity in anti-inflammatory assays.