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      • KCI등재후보SCOPUS

        Effect of Substitutional Doping on Temperature Dependent Electrical Parameters of Amorphous Se-Te Semiconductors

        Neha,Sharma,Sunanda,Sharda,Dheeraj,Sharma,Vineet,Sharma,P.,B.,Barman,S.C.,Katyal,Pankaj,Sharma,S.,K.,Hazra 대한금속·재료학회 2013 ELECTRONIC MATERIALS LETTERS Vol.9 No.5

        Steady state current-voltage characteristics of the amorphous (Se80Te20)98Y2 (Y = Ag, Bi, Ge, Cd) semiconductors at different temperatures are reported. The measurements were performed using direct-current voltage bias to understand the basic conductivity mechanism and to evaluate the impact of each substituent on electrical response. The space charge limited conduction mechanism, and the density of states near Fermi level have been calculated. The difference in electrical response due to different substitutions in the glassy matrix is analyzed.

      • SCIESCOPUSKCI등재

        Experimental investigation of effective atomic numbers for some binary alloys

        Sharma,,Renu,Sharma,,J.K.,Kaur,,Taranjot,Singh,,Tejbir,Sharma,,Jeewan,Singh,,Parjit,S. Korean Nuclear Society 2017 Nuclear Engineering and Technology Vol.49 No.7

        In the present work, the gamma ray backscattering technique was used to determine the effective atomic numbers for certain binary alloys. With the help of a muffle furnace, the binary alloys were synthesized using the melt quenching technique with different compositions of $_{82}Pb$, $_{50}Sn$, and $_{30}Zn$. The intensity distribution of backscattered photons from radioactive isotope $^{22}Na$ (511 keV) was recorded with the help of GAMMARAD5 [$76mm{\times}76mm$ NaI(Tl) scintillator detector] and analyzed as a function of both atomic number and thickness of the target material. The effective atomic numbers for the same binary alloys were also computed theoretically using the atomic to electronic cross-section method with the help of the mass attenuation coefficient database of WinXCom (2001). Good agreement was observed between theoretical and experimental results for the effective atomic numbers of all the selected alloys.

      • Triple Negative Breast Cancer in People of North East India: Critical Insights Gained at a Regional Cancer Centre

        Sharma,,Mousumi,Sharma,,Jagannath,Dev,Sarma,,Anupam,Ahmed,,Shiraj,Kataki,,Amal,Chandra,Saxena,,Rahul,Sharma,,Dilutpal Asian Pacific Organization for Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.11

        Background: Breast cancer is a heterogeneous disease comprising of distinct biological subtypes with many targeted prognostic biomarkers having therapeutic implications. However, no specific targeted therapy for triple negative breast cancer has been discovered to date and hence further research is needed. Aim: The aim and objectives of the present study were to examine the prevalence of triple negative breast cancer (TNBC) in North-East India and to compare the clinicopathological parameters in two study groups defined by immunohistochemistry (IHC) - "TNBC" and "Others". Materials and Methods: We carried out a retrospective study in a cohort of 972 patients diagnosed with invasive breast carcinoma in the Department of Pathology, Dr. B. Borooah Cancer Institute, a Regional Cancer Centre for treatment and research, Guwahati, for a period of 3 years and 10 months from January 2010 to October 2013. Based on IHC findings, patients were divided into two groups - "TNBC" and "Others". All relevant clinicopathological parameters were compared in both. TNBC were defined as those that were estrogen receptor (ER), progesterone receptor (PR), and HER2/neu negative while those positive for any of these markers were defined as "Others". Results: In this study, out of total 972 cases 31.9% (310 cases) were defined as TNBC and 662 cases (68.1%) as "Others" based on IHC markers. Compared to the "Others" category, TNBC presented at an early age (mean 40 years), were associated with high grade large tumours and high rate of node positivity, IDC NOS being the most common histological subtype in TNBC. Conclusions: TNBC accounts for a significant portion of breast cancers in this part of India and commonly present at younger age and tend to be large high grade tumours.

      • Effect of Fading on Performance of VANET in Realistic Scenarios Using NCTUns6.0

        Richa,Sharma,Jyoteesh,Malhotra,Komal,Sharma 보안공학연구지원센터 2015 International Journal of Future Generation Communi Vol.8 No.1

        Road safety and increasing transport efficiency are the important goals for intelligent transport system (ITS). Vehicular Ad hoc Network is such a network which can help to achieve these goals. VANET routing is a crucial task for reliable communication among vehicles. The impact of fading on network throughput and packet drop is explored in this paper. Interesting results show the performance evaluation of without fading environment and Rayleigh fading in different scenarios. NCTUns 6.0 (National Chiao Tung University Network Simulator) is used to justify our results that is a GUI based open source platform for vehicular Ad-Hoc network. Various performance issues are also surveyed with the help of this simulator.

      • KCI등재SCOPUS

        Experimental investigation of effective atomic numbers for some binary alloys

        Renu,Sharma,J.K.,Sharma,Taranjot,Kaur,Tejbir,Singh,Jeewan,Sharma,Parjit,S.,Singh 한국원자력학회 2017 Nuclear Engineering and Technology Vol.49 No.7

        In the present work, the gamma ray backscattering technique was used to determine the effective atomic numbers for certain binary alloys. With the help of a muffle furnace, the binary alloys were synthesized using the melt quenching technique with different compositions of 82Pb, 50Sn, and 30Zn. The intensity distribution of backscattered photons from radioactive isotope 22Na (511 keV) was recorded with the help of GAMMARAD5 [76 mm × 76 mm NaI(Tl) scintillator detector] and analyzed as a function of both atomic number and thickness of the target material. The effective atomic numbers for the same binary alloys were also computed theoretically using the atomic to electronic cross-section method with the help of the mass attenuation coefficient database of WinXCom (2001). Good agreement was observed between theoretical and experimental results for the effective atomic numbers of all the selected alloys.

      • Data Protection in Clouds using Two Stage Encryption

        Pallav,Sharma,Varsha,Sharma,Sanjeev,Sharma,Jitendra,Agrawal 보안공학연구지원센터 2015 International Journal of Grid and Distributed Comp Vol.8 No.4

        Cloud Computing has been an emergent technology that has opened the space for virtualization, as it provides many computational services and storage services over the Internet with the help of a browser. Cloud computing's core comprises of services like platform, infrastructure and software as a service. The unpredicted boom in cloud computing is driven by its simple economic benefit. It helps in reducing capital expenses and minimizes operating expenses. This move however, has increased a major concern about the protection of data, as against the traditional system the data is now stored online and is far easily exposed than we realize. This raises a major security issue for data protection. Many techniques for protection of data have been proposed so far. However, the best available option till date is to encrypt user data before storing it over the cloud environment and decrypting it again before handing the data back to the cloud user. In this paper, we introduce a more efficient and stronger encryption process that allows a cloud service provider to protect user data more efficiently.

      • KCI등재후보SCOPUS

        Non-destructive evaluation of steel and GFRP reinforced beams using AE and DIC techniques

        Gaurav,Sharma,Shruti,Sharma,Sandeep,K.,Sharma 국제구조공학회 2021 Structural Engineering and Mechanics, An Int'l Jou Vol.77 No.5

        The paper presents an investigation of the widely varying mechanical performance and behaviour of steel and Glass Fibre Reinforced Polymer (GFRP) reinforced concrete beams using non-destructive techniques of Acoustic Emission (AE) and Digital Image Correlation (DIC) under four-point bending. Laboratory experiments are performed on both differently reinforced concrete beams with 0.33%, 0.52% and 1.11% of tension reinforcement against balanced section. The results show that the ultimate load-carrying capacity increases with an increase in tensile reinforcement in both cases. In addition to that, AE waveform parameters of amplitude and number of AE hits successfully correlates and picks up the divergent mechanism of cracking initiation and progression of failure in steel reinforced and GFRP reinforced concrete beams. AE activity is about 20- 30% more in GFRP-RC beams as compared to steel-RC beams. It was primarily due to the lower modulus of elasticity of GFRP bars leading to much larger ductility and deflections as compared to steel-RC beams. Furthermore, AE XY event plots and longitudinal strain profiles using DIC gives an online and real-time visual display of progressive AE activity and strains respectively to efficaciously depict the crack evolution and their advancement in steel-RC and GFRP-RC beams which show a close matching with the micro-and macro-cracks visually observed in the actual beams at various stages of loading.

      • KCI등재SCOPUS

        Effect of Te on Linear and Non-linear Optical Properties of New Quaternary Ge-Se-Sb-Te Chalcogenide Glasses

        Neha,Sharma,Sunanda,Sharda,S.C.,Katyal,Vineet,Sharma,Pankaj,Sharma 대한금속·재료학회 2014 ELECTRONIC MATERIALS LETTERS Vol.10 No.1

        We report linear and non-linear optical properties of a new quaternary chalcogenide glass series Ge19-ySe63.8Sb17.2Tey (y = 0, 2, 4, 6, 8, 10). In linear optical properties; refractive index, extinction coefficient and the Tauc gap are reported and their variation with Te content has been discussed. In non-linear properties; third order nonlinear susceptibility and non-linear refractive index has been discussed. The variation of non-linear refractive index has also been reported with normalized photon energy. A correlation between the Tauc gap and nonlinear refractive index has been discussed. Results indicate that these materials may find applications in modern optical devices.

      • Chemopreventive Efficacy of Moringa oleifera Pods Against 7, 12-Dimethylbenz[a]anthracene Induced Hepatic Carcinogenesis in Mice

        Sharma,,Veena,Paliwal,,Ritu,Janmeda,,Pracheta,Sharma,,Shatruhan Asian Pacific Organization for Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.6

        Oxidative stress is a common mechanism contributing to initiation and progression of hepatic damage in a variety of liver disorders. Hence there is a great demand for the development of agents with potent antioxidant effect. The aim of the present investigation is to evaluate the efficacy of Moringa oleifera as a hepatoprotective and an antioxidant against 7, 12-dimethylbenz[a]anthracene induced hepatocellular damage. Single oral administration of DMBA (15 mg/kg) to mice resulted in significantly (p<0.001) depleted levels of xenobiotic enzymes like, cytochrome P450 and b5. DMBA induced oxidative stress was confirmed by decreased levels of reduced glutathione (GSH) and glutathione-S-transferase (GST) in the liver tissue. The status of hepatic aspartate transaminase (AST), alanine transaminase (ALT), and alkaline phosphatase (ALP) which is indicative of hepatocellular damage were also found to be decreased in DMBA administered mice. Pretreatment with the Moringa oleifera (200 and 400 mg/kg) orally for 14 days significantly reversed the DMBA induced alterations in the liver tissue and offered almost complete protection. The results from the present study indicate that Moringa oleifera exhibits good hepatoprotective and antioxidant potential against DMBA induced hepatocellular damage in mice that might be due to decreased free radical generation.

      • SCOPUSKCI등재

        Antidiabetic Activity of an Ayurvedic Formulation Chaturmukha Rasa: A Mechanism Based Study

        Sharma,,Akansha,Tiwari,,Raj,K,Sharma,,Vikas,Pandey,,Ravindra,K,Shukla,,Shiv,Shnakar KOREAN PHARMACOPUNCTURE INSTITUTE 2019 Journal of pharmacopuncture Vol.22 No.2

        Objectives: The objective of this study was to evaluate antidiabetic activity of Chaturmukha rasa based on streptozotocin induced diabetes model, alpha amylase inhibitory activity, alpha Glucosidase inhibitory activity and inhibition of sucrase. Methods: Chaturmukha rasa was prepared as per Ayurvedic formulary. Antidiabetic activity was measured in experimentally streptozotocin induced rats. The dose was taken as 45 mg/kg, i.p. The antidiabetic activity of Chaturmukha rasa was compared Triphala Kwatha, a marketed formulation. Further In vitro $\acute{\alpha}$- Amylase Inhibitory Assay, In vitro salivary amylase Inhibitory Assay, In vitro ${\alpha}-Glucosidase$ Inhibitory Assay and In vitro Sucrase Inhibitory Assay was performed with respect to Chaturmukha rasa. The IC50 value was calculated for all the above activity. Results: Streptozotocin with Acarbose showed significant decrease in blood glucose level whereas streptozotocin with Triphala kwatha showed more decrease in blood glucose level than Streptozotocin with Acarbose. The combination of Streptozotocin + Triphala kwatha + Chaturmukha rasa showed a significant decrease in blood glucose level on 21st day. In vitro $\acute{\alpha}$- Amylase Inhibitory Assay the Chaturmukha rasa showed IC50 value $495.94{\mu}l$ when compared with Acarbose $427.33{\mu}l$, respectively. In the ${\alpha}-Glucosidase$ Inhibitory Assay Chaturmukha rasa showed IC50 value $70.93{\mu}l$ when compared with Acarbose $102.28{\mu}l$, respectively. In vitro Sucrase Inhibitory Assay Chaturmukha rasa showed IC50 value $415.4{\mu}l$ when compared with Acarbose $371.43{\mu}l$, respectively. Conclusion: This study supports that Chaturmukha rasa may inhibit diabetes by inhibition of salivary amylase or alpha Glucosidase or sucrase. This may be the mechanism by which Chaturmukha rasa inhibits diabetes. Further this study supports the usage of Chaturmukha rasa for the management of diabetes.

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