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      • KCI등재

        Scour Protection around Vertical-Wall Bridge Abutments with Collars

        Serife Yurdagul Kumcu,Mehmet Ali Kokpinar,Mustafa Gogus 대한토목학회 2014 KSCE JOURNAL OF CIVIL ENGINEERING Vol.18 No.6

        The cause of local scour around a bridge abutment is mainly the presence of spiraling vortex flow structure called the principalvortex. A rigid surface around an abutment with a collar can arrest the growth of the vortex, and therefore, reduces the scour depthsaround the abutment compared to the case without a collar. This paper presents an experimental investigation related to the collars ofdifferent sizes placed around vertical-wall bridge abutments at various elevations in an erodible bed flume that consists of twodifferent types of almost uniform sand of (d50)1 = 1.48 mm and (d50)2 = 0.90 mm to show the effect of collars on the scour depthsaround the abutments. A series of experiments were conducted at the laboratory under clear-water conditions at flow intensity of U/Uc =0.90, where U is the average velocity of the approach flow and Uc is the critical flow velocity for the sediment motion. The maximumscour depths forming around the abutments were determined at the end of each experiment conducted with and without collar for atime period of 6 hours. Experimental results showed that, a collar placed on the abutment at or below the bed level is able to reducethe maximum scour depth around the abutment by 70-100% as a function of the collar and abutment sizes in comparison to that of anunprotected abutment. The optimum location of a collar on a vertical-wall abutment, which will result in the maximum percentagereduction in the maximum scour depth, is generally below the bed level and can be expressed as a function of the dimensionlessabutment length and collar width. It was also observed that although the abutment itself was protected, the collars of larger sizes shiftthe scour region away towards downstream from the abutment, with scour depths smaller than the maximum scour depth at theabutment for the case of no collar. The experimental observations and analysis presented in this study established that the optimumdimensionless location of the collar on the abutment which yields the maximum scour reduction was not affected by the sedimenthaving finer diameter. Therefore, abutment-collar arrangements could be an appropriate alternative solution to riprap protection thatis widely used in practice in countering scour problems at bridge abutments.

      • KCI등재

        Preconcentration of Iron(III), Lead(II), Cobalt(II) and Chromium(III) on Amberlite XAD-1180 Resin Loaded with 4-(2-Pyridylazo)-resorcinol (PAR) and Their Determination by FAAS

        Serife Tokalloglu,Senol Kartal 대한화학회 2006 Bulletin of the Korean Chemical Society Vol.27 No.9

        In this study, a solid phase extraction method has been developed for the preconcentration and separation of the elements Cr(III), Fe(III), Co(II) and Pb(II) at trace levels by using a column packed with Amberlite XAD-1180 resin loaded with 4-(2-pyridylazo)-resorcinol (PAR) reagent. After preconcentrating, the metals retained on the column were eluted with 20 mL of 3 mol/L HNO3 and then determined by flame atomic absorption spectrometry (FAAS). The factors affecting the recovery of the elements, such as pH, type and concentration of eluent, volume of sample and elution solution, and matrix components, were also ascertained. The recoveries of Cr(III), Fe(III), Co(II) and Pb(II) were found to be 99 4, 97 3, 95 3 and 98 4%, respectively, under the optimum conditions at 95% confidence level and the relative standard deviations found by analyzing of nine replicates were ??4.4%. The preconcentration factors for Cr(III), Fe(III), Co(II) and Pb(II) were found as 75, 125, 50 and 75 respectively. The detection limits (DL, 3s/b) were 3.0 g/L for Cr(III), 1.25 g/L for Fe(III), 3.3 g/L for Co(II), and 7.2 g/L for Pb(II). The recoveries achieved by adding of metals at known concentrations to samples and the analysis results of Buffalo river sediment (RM 8704) show that the described method has a good accuracy. The proposed method was applied to tap water, stream water, salt and street dust samples.

      • KCI등재

        Evaluation of Portal Venous Velocity with Doppler Ultrasound in Patients with Nonalcoholic Fatty Liver Disease

        Serife Ulusan,Tolga Yakar,Zafer Koc 대한영상의학회 2011 Korean Journal of Radiology Vol.12 No.4

        Purpose: We examined the relationship between portal venous velocity and hepatic-abdominal fat in patients with nonalcoholic fatty liver disease (NAFLD), using spectral Doppler ultrasonography (US) and magnetic resonance imaging (MRI). Materials and Methods: In this prospective study, 35 patients with NAFLD and 29 normal healthy adults (control group) underwent portal Doppler US. The severity of hepatic steatosis in patients with NAFLD was assessed by MRI through chemical shift imaging, using a modification of the Dixon method. Abdominal (intra-abdominal and subcutaneous) fat was measured by MRI. Results: The difference in portal venous velocity between the patients with NAFLD and the control group was significant (p < 0.0001). There was no correlation between the degree of abdominal or hepatic fat and portal venous velocity (p > 0.05). There were strong correlations between the hepatic fat fraction and subcutaneous adiposity (p < 0.0001), intraperitoneal fat accumulation (p = 0.017), and retroperitoneal fat accumulation (p < 0.0001). Conclusion: Our findings suggest that patients with NAFLD have lower portal venous velocities than normal healthy subjects. Purpose: We examined the relationship between portal venous velocity and hepatic-abdominal fat in patients with nonalcoholic fatty liver disease (NAFLD), using spectral Doppler ultrasonography (US) and magnetic resonance imaging (MRI). Materials and Methods: In this prospective study, 35 patients with NAFLD and 29 normal healthy adults (control group) underwent portal Doppler US. The severity of hepatic steatosis in patients with NAFLD was assessed by MRI through chemical shift imaging, using a modification of the Dixon method. Abdominal (intra-abdominal and subcutaneous) fat was measured by MRI. Results: The difference in portal venous velocity between the patients with NAFLD and the control group was significant (p < 0.0001). There was no correlation between the degree of abdominal or hepatic fat and portal venous velocity (p > 0.05). There were strong correlations between the hepatic fat fraction and subcutaneous adiposity (p < 0.0001), intraperitoneal fat accumulation (p = 0.017), and retroperitoneal fat accumulation (p < 0.0001). Conclusion: Our findings suggest that patients with NAFLD have lower portal venous velocities than normal healthy subjects.

      • KCI등재

        Cytotoxicity of temporary cements on bovine dental pulp-derived cells (bDPCs) using realtime cell analysis

        serife Buket Bozkurt,Abdulkadir sengun,Sema Sezgin Hakki,Necla Demİr,Meral Arslan Malkoc 대한치과보철학회 2015 The Journal of Advanced Prosthodontics Vol.7 No.1

        PURPOSE To evaluate the cytotoxicity of temporary luting cements on bovine dental pulp-derived cells (bDPCs). MATERIALS AND METHODS Four different temporary cements were tested: Rely X Temp E (3M ESPE), Ultratemp (Ultradent), GC Fuji Temp (GC), and Rely X Temp NE (3M ESPE). The materials were prepared as discs and incubated in Dulbecco's modified eagle's culture medium (DMEM) for 72 hours according to ISO 10993-5. A real-time cell analyzer was used to determine cell vitality. After seeding 200 µL of the cell suspensions into the wells of a 96-well plate, the bDPCs were cured with bioactive components released by the test materials and observed every 15 minutes for 98 hours. One-way ANOVA and Tukey-Kramer tests were used to analyze the results of the proliferation experiments. RESULTS All tested temporary cements showed significant decreases in the bDPCs index. Rely X Temp E, GC Fuji Temp, and Rely X Temp NE were severely toxic at both time points (24 and 72 hours) (P<.001). When the cells were exposed to media by Ultratemp, the cell viability was similar to that of the control at 24 hours (P>.05); however, the cell viability was significantly reduced at 72 hours (P<.001). Light and scanning electron microscopy examination confirmed these results. CONCLUSION The cytotoxic effects of temporary cements on pulpal tissue should be evaluated when choosing cement for luting provisional restorations.

      • Poster Session : PS 0276 ; Gastroenterology : Gastrointestinal Tract Hemorrhage Due to Angiodysplasia in Hutchinson Gilfort Progeria Syndrome

        ( Serife Hanife Aktas ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Hutchinson Gilfort Progeria Syndrome (HGPS) is an aging disease which encounters in childhood and includes a higher risk for atherosclerosis, cerebrovascular event, stroke and coronary artery disease. Angiodysplasia in the gastrointestinal (GIS) tract can be seen as a cause of hemorrhage rarely. 15 years female Progeria patient which the diagnose was established before. The patient admitted our center with dyspeptic symtoms such as neusea, vomit, bloating and described the blackness in the stool. In the patient`s history, GIS tract hemorrhage was occured and treated in the another region hospital, two months ago. In the physical examination, decreased subcutaneous fat tissue, thin skin structure, micrognaty, thin top and bottom lip structure were inspected. Cardiovascular and respiratory system examination displayed normal fi ndings. Melena was not examinated in rectal examination. Laboratory fi ndings were normal between ranges except mild hypochromic anemia and hypothyroidism; hemoglobin:12 g/dL (12 - 18), hematocrit: 38 % (37 -48), ferritin: 139 ng/mL (4. 6 - 204), iron: 19 μg/dL (50 - 170), TIBC:269(141-519) thyroidstimulan hormone (TSH) : 6. 1 mIU/L (0. 4 - 3. 4), free T4: 1. 0 ng/dL (0. 9 - 1. 5), anti thyroglobulin: 113 IU/mL (0 - 57), anti thyroid peroxidase:267 IU/mL (0 - 64), sedimentation: 39 mm/hour. Intact and diffuse type angiodysplasia on the gastric mucosa was identifi ed by the gastroscopy. There were no any bleeding signs and medical treatment (proton pump inhibitor and sucralfate) was applied. Also, hypothyroidism was treated by the levo-thyroxin preparate. For the mild hypochromic and iron defi cient anemia, iron containing preparate added to the treatment after discharge. In the literature, there was not coincided HGPS case with hemorrhagic angiodisplasia, commonly. This case report was represented to emphasize HGPS associated angiodisplasia as a rare cause of anemia and GIS tract hemorrhage.

      • KCI등재

        Investigation of Flow Over Spillway Modeling and Comparison between Experimental Data and CFD Analysis

        Serife Yurdagul Kumcu 대한토목학회 2017 KSCE JOURNAL OF CIVIL ENGINEERING Vol.21 No.3

        As a part of design process for hydro-electric generating stations, hydraulic engineers typically conduct some form of model testing. The desired outcome from the testing can vary considerably depending on the specific situation, but often characteristics such as velocity patterns, discharge rating curves, water surface profiles, and pressures at various locations are measured. Due to recent advances in computational power and numerical techniques, it is now also possible to obtain much of this information through numerical modeling. In this paper, hydraulic characteristics of Kavsak Dam and Hydroelectric Power Plant (HEPP), which are under construction and built for producing energy in Turkey, were investigated experimentally by physical model studies. The 1/50-scaled physical model was used in conducting experiments. Flow depth, discharge and pressure data were recorded for different flow conditions. Serious modification was made on the original project with the experimental study. In order to evaluate the capability of the computational fluid dynamics on modeling spillway flow a comparative study was made by using results obtained from physical modeling and Computational Fluid Dynamics (CFD) simulation. A commercially available CFD program, which solves the Reynolds-averaged Navier-Stokes (RANS) equations, was used to model the numerical model setup by defining cells where the flow is partially or completely restricted in the computational space. Discharge rating curves, velocity patterns and pressures were used to compare the results of the physical model and the numerical model. It was shown that there is reasonably good agreement between the physical and numerical models in flow characteristics.

      • SCOPUSKCI등재

        Preconcentration and Determination of Fe(III) from Water and Food Samples by Newly Synthesized Chelating Reagent Impregnated Amberlite XAD-16 Resin

        Tokahoglu, Serife,Ergun, Hasan,Cukurovah, Alaaddin Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.7

        A simple and reliable method has been developed to selectively separate and concentrate trace amounts of Fe(III) ions from water and food samples by using flame atomic absorption spectrometry. A new reagent, 5-hydroxy-4-ethyl-5,6-di-pyridin-2-yl-4,5-dihydro-2H-[1,2,4] triazine-3-thione, was synthesized and characterized by using FT-IR spectroscopy and elemental analysis. Effects of pH, concentration and volume of elution solution, sample flow rate, sample volume and interfering ions on the recovery of Fe(III) were investigated. The optimum pH was found to be 5. Eluent for quantitative elution was 10 mL of 2 M HCl. The preconcentration factor of the method, detection limit (3s/b, ${\mu}gL^{-1}$) and relative standard deviation values were found to be 25, 4.59 and 1%, respectively. In order to verify the accuracy of the method, two certified reference materials (TMDA 54.4 lake water and SRM 1568a rice flour) were analyzed. The results obtained were in good agreement with the certified values. The method was successfully applied to the determination of Fe(III) ions in water and food samples.

      • Effect of Pulsed Electromagnetic Field on MMP-9 and TIMP-1 Levels in Chondrosarcoma Cells Stimulated with IL-1β

        Caliskan, Serife Gokce,Bilgin, Mehmet Dincer,Kozaci, Leyla Didem Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.7

        Chondrosarcoma, the second most common type of bone malignancy, is characterized by distant metastasis and local invasion. Previous studies have shown that treatment by pulsed electromagnetic field (PEMF) has beneficial effects on various cancer cells. In this study, we investigated the effects of PEMF applied for 3 and 7 days on the matrix metalloproteinase (MMP) levels in chondrosarcoma SW1353 cells stimulated with two different doses of $IL-1{\beta}$. SW1353 cells were treated with (0.5 and 5 ng/ml) $IL-1{\beta}$ and PEMF exposure was applied either 3 or 7 days. MMP-9 and TIMP-1 levels were measured in conditioned media by enzyme-linked immunosorbent assay. The results were relative to protein levels. Statistical analyses were performed using one-way analysis of variance (ANOVA). P<0.05 was considered significant. PEMF treatment significantly decreased MMP-9 protein levels in human chondrosarcoma cells stimulated with 0.5 ng/ml $IL-1{\beta}$ at day 7, whereas it did not show any effect on cells stimulated with 5 ng/ml $IL-1{\beta}$. There was no significant change in TIMP-1 protein levels either by $IL-1{\beta}$ stimulation or by PEMF treatment. The results of this study showed that PEMF treatment suppressed $IL-1{\beta}$-mediated upregulation of MMP-9 protein levels in a dual effect manner. This finding may offer new perspectives in the therapy of bone cancer.

      • SCIESCOPUSKCI등재

        The Effect of Clinoptilolite in Low Calcium Diets on Performance and Eggshell Quality Parameters of Aged Hens

        Gezen, Serife Sule,Eren, Mustafa,Balci, Faruk,Deniz, Gulay,Biricik, Hakan,Bozan, Birgul Asian Australasian Association of Animal Productio 2009 Animal Bioscience Vol.22 No.9

        Ninety six beak-trimmed 72 week-old Lohmann Brown hens were randomly divided into four equal groups. Each group comprised 4 replicates. Isoenergetic and isonitrogenous experimental diets contained low calcium (3.5%); optimum calcium (4.2%); low Ca (3.5% Ca)+1% Clinoptilolite (CLP); low Ca (3.5% Ca)+2% CLP. Data were collected biweekly and the experiment lasted 6 weeks. Egg production, feed consumption, feed conversion ratio, egg weight, tibia Ca, P, ash and eggshell thickness were not affected by addition of CLP to the diets (p>0.05). There were no significant differences in egg shell strength and ash when data were analyzed individually in measurement periods ($74^{th}$, $76^{th}$ and $78^{th}$ weeks). However, according to pooled data ($74^{th}$-$78^{th}$ weeks), eggshell strength was increased (p<0.05) only by 2% CLP supplementation versus low Ca (3.5%) diet, and shell ash was significantly increased by 2% CLP supplementation compared with the other diets. The damaged egg ratio on 1% and 2% CLP diets was significantly decreased between 76-78 weeks'data when compared with the low Ca diet. However; damaged egg ratio on the 2% CLP diet was significantly decreased when pooled data (74-78) were compared with no CLP diets. The differences in marketable egg ratio paralleled damaged egg ratio. The plasma calcium level at the end of experiment was increased on the 2% CLP diet when compared with the low Ca (3.5%) diet (p<0.05). Furthermore, at the end of the experiment a marked decrease of manure moisture was observed on both CLP diets (p<0.01). In conclusion, Clinoptilolite (2%) supplementation to layer diets tends to improve eggshell quality and manure dry matter (1% and 2% CLP) after six weeks.

      • SCOPUSKCI등재

        Preconcentration of Iron(III), Lead(II), Cobalt(II) and Chromium(III) on Amberlite XAD-1180 Resin Loaded with 4-(2-Pyridylazo)-resorcinol (PAR) and Their Determination by FAAS

        Tokalloglu, Serife,Kartal, Senol Korean Chemical Society 2006 Bulletin of the Korean Chemical Society Vol.27 No.9

        In this study, a solid phase extraction method has been developed for the preconcentration and separation of the elements Cr(III), Fe(III), Co(II) and Pb(II) at trace levels by using a column packed with Amberlite XAD-1180 resin loaded with 4-(2-pyridylazo)-resorcinol (PAR) reagent. After preconcentrating, the metals retained on the column were eluted with 20 mL of 3 mol/L $HNO_3$ and then determined by flame atomic absorption spectrometry (FAAS). The factors affecting the recovery of the elements, such as pH, type and concentration of eluent, volume of sample and elution solution, and matrix components, were also ascertained. The recoveries of Cr(III), Fe(III), Co(II) and Pb(II) were found to be $99\;{\pm}\;4,\;97\;{\pm}\;3,\;95\;{\pm}\;3$ and $98\;{\pm}\;4$%, respectively, under the optimum conditions at 95% confidence level and the relative standard deviations found by analyzing of nine replicates were $\leq4.4$%. The preconcentration factors for Cr(III), Fe(III), Co(II) and Pb(II) were found as 75, 125, 50 and 75 respectively. The detection limits (DL, 3s/b) were 3.0 $\mu g/L$ for Cr(III), 1.25 $\mu g/L$ for Fe(III), 3.3 $\mu g/L$ for Co(II), and 7.2 $\mu g/L$ for Pb(II). The recoveries achieved by adding of metals at known concentrations to samples and the analysis results of Buffalo river sediment (RM 8704) show that the described method has a good accuracy. The proposed method was applied to tap water, stream water, salt and street dust samples.

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