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최창주,서강성,박수강,조금배,백형래,임병옥 조선대학교 에너지.자원신기술연구소 2002 에너지·자원신기술연구소 논문지 Vol.24 No.2
Single phase induction motor(SPIM) is one of the most widely used type of low power AC motors in the world, especially for domestic or commercial applications where a three phase power supply is not available. Fractional horse power single phase induction motors have no starting torque their own. So there are several ways of starting single phase induction motors. The most common type is the starting capacitor installed in series with the auxiliary winding to increase the starting torque. Also, the auxiliary winding is disconnected once the speed of the motor reaches 70 to 80% of the rated speed. In the conventional systems, this function is conducted by a centrifugal switch. But the mechanical centrifugal switch has many problems such as switch malfunction. This paper presents the new methods of universal starting switch by digital controller to overcome these shortcomings of centrifugal switch.
유세포 측정을 통한 CD34^(+)세포의 정량방법 비교
양형모,서영훈,엄현석,민창기,김희제,정대철,이종욱,진종율,한치화,김춘추,김학주 대한조혈모세포이식학회 1998 대한조혈모세포이식학회지 Vol.3 No.2
본 연구소에서는 현재 CD34^(+) 세포의 정량에 사용되고 있는 4가지 서로 다른 방법을 가지고 골수에 적용하여 그 결과를 비교하였다. 각각의 방법들이 편리한 점과 불리한 점들을 가지고 있었지만, 통계적으로는 유의한 차이를 보이지 않았다. 1) CD34-PE/CD45-FITC 방법13(ISHAGE: International Society of Hematotherapy and Graft Engineering), 2) CD34-PE/CD14-FITC 방법, 3) CD34-PE/CD14-FITC/CD45-PerCP 방법, 4) DNA dye/CD34-PE/CD45-PerCP4(Becton Dickinson) 등을 비교하였으며 그 결과 CD34^(+) 세포의 농도는 다음과 같았다. 1) 0.473±0.345, (%Mean±SD, N=70) 2) 0.663±0.519, (N=20), 3) 0.543±0.381 (N=46), 4) 0.624±0.341, (N=32). 시료로는 여의도 성모병원 카톨릭 조혈모세포이식 센터에서 채혈한 골수를 이용하였다. Four different methods for flow cytometric quantitation of CD34+ cell were compared using bone marrow samples (n=168). Following combination of antibodies were used for the analysis : A) CD45-FITC/CD34-PE (n=70), B) CD14-FITC/CD34-PE (n=20), C) CD14-FITC /CD34-PE /CD45-PerCP(n=46), D) DNA dye/CD34-PE/CD45-PerCP (n=32). Each method showed no significant differences among them (P=0.126, ANOVA test, SPSS Version 7.5). When we compare these methods using same samples (n=12), the P value became 0.832. The mean % of CD34+ cells calculated in this experiment were A) 0.474%, B) 0.663%, C) 0.548%, D) 0.624% respectively. In our laboratory, we decided to use CD45-FITC/CD34-PE methods as a routine protocol.
Balanced Scorecard 실행을 위한 System Dynamics의 활용에 관한 연구
盧亨鳳,徐允周 홍익대학교 동북아연구소 2001 東北亞硏究 Vol.5 No.-
This paper discusses the potential of system dynamics modelling to support balanced scorecard. The balanced scorecard is a conceptual framework for translating an organisation's strategy into a set of performance indicators. These performance indicators are distributed across the 'classic' model's four perspective: Customers, Internal Business Processes, Financial, and Learning and Growth. This balanced scorecard, while having significant strength, suffers from the limitation of all performance indicator systems, namely that the interrelationships between indicators are overlooked and there is no way of taking into account the impact of delayed feedback which flows from introduction of new policy and legislative changes. System Dynamics is a methodology for understanding complex problems where there is dynamic behaviour and where feedback impacts significantly on system outcomes. System dynamics provides a rigorous basis for qualitative testing of the effects of performance indicators in complex environments. This can be supplemented with quantitative system dynamics simulation tools that further test the validity of indicators and the business rules implicit in them. System dynamics modelling has an important role to play in extending feedback cycle in performance measurements to a full systems approach.
개심술(開心術)의 임상적 고찰 : 치험 200예 200 Cases
최형호,서홍주,임영혁,김정중,배대양,이석기,임진수 조선대학교 부설 의학연구소 2002 The Medical Journal of Chosun University Vol.27 No.2
Background and Objectives: Two hundred cases of the open heart surgery due to congenital and acquired heart disease were done using the cardiopulmonary bypass in the Department of Thoracic and Cardiovascular surgery, Chosun University Hospital from November, 1980 to June, 2001. Material and Methods: The number of congenital heart disease was 132 cases. 68 cases were acquired heart disease. 'The age of the congenital heart disease was from 22 days to 45 years. In the acquired heart disease, the age was from 14 to 72 years. Result: Congenital heart disease consisted of 113 congenital acyanotic heart disease, 19 congenital cyanotic heart disease. Corrective operation was done for congenital heart disease with 4. 5 % operative mortality. Of 68 cases acquired heart disease, 44 patients were valvular heart disease, 3 cardiac tumors, 9 ischemic heart diseases, 12 aortic dissections and etc. The operative mortality was 13%. Conclusion: The postoperative complications were appeared in 68 cases and the complications were wound infection, occipital alopecia, low cardiac output syndrome, arrhythmia, septicemia etc. The mortality after open heart surgery was 15 cases and the causes of death were low cardiac output syndrome, septicemia, respiratory failure and left ventricle rupture.
최영호,서홍주,임영혁,김정중,박성강,이석기,임진수,김은규 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2
Pulmonary blastoma is a very rare primary neoplasm of the lung. We experienced a case of pulmonary blastoma in a 40 years old man. The mediobasal segmentectomy of the right lower lobe was performed. The patient was discharge on the postoperative days 6. There is no evidence of recurrence or metastasis on followup study during 7 months period after operation.
Clinicopathologic characteristics and outcomes of gastric cancers with the MSI-H phenotype
Seo, Hyung Min,Chang, Yeon Soo,Joo, Sun Hyung,Kim, Youn Wha,Park, Yong-Koo,Hong, Sung Wha,Lee, Suk-Hwan Wiley Subscription Services, Inc., A Wiley Company 2009 Journal of surgical oncology Vol.99 No.3
<B>Objectives</B><P>We examined the correlation between microsatellite instability (MSI) status and the clinicopathological features and prognostic value in gastric cancer and compared the efficacy of immunohistochemical staining for hMLH1 and hMSH2 with a polymerase chain reaction (PCR)-based test.</P><B>Methods</B><P>MSI status was examined in 328 consecutive gastric adenocarcinomas using tissue preserved in paraffin blocks. DNA extracted from tumor sections and the corresponding normal tissue was analyzed using PCR at the five microsatellite loci recommended by the National Cancer Institute (NCI). Immunohistochemical staining for hMLH1 and hMSH2 was performed and the results were compared with the MSI status measured using PCR. The relationship of the clinicopathologic variables to MSI status was analyzed.</P><B>Results</B><P>Of the gastric cancers, 8.2% (n = 27) contained MSI-H and this was associated with older age (>70 years), distal tumor location, tumor size, and intestinal subtype. Lymphatic and vascular invasion were associated with the disease-free survival. On immunohistochemical staining, the loss of expression of hMLH1 or hMSH2 was observed in 11% (n = 36). The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of immunohistochemical staining were 63.0%, 93.7%, 47.2%, 96.6%, and 91.2%, respectively.</P><B>Conclusions</B><P>Gastric cancers with MSI-H have specific clinicopathologic characteristics, such as older age at diagnosis, distal tumor location, increased tumor size, and intestinal histologic type. However, immunohistochemical staining for hMLH1 and hMSH2 is not as accurate as the PCR-based MSI test. J. Surg. Oncol. 2009;99: 143–147. © 2008 Wiley-Liss, Inc.</P>
Paclitaxel-Platinum 제제를 기본으로 한 항암화학요법 후 재발한 난소암 환자에서 Paclitaxel-Carboplatin 복합항암화학요법의 효용성
서형주 ( Hyung Joo Seo ),이철민 ( Chul Min Lee ),김정선 ( Jaung Sun Kim ),이혜주 ( Hye Joo Lee ),박용주 ( Yong Joo Park ),조용균 ( Yong Kyoon Cho ),최훈 ( Hoon Choi ),김복린 ( Bok Rin Kim ),이홍균 ( Hong Kyoon Lee ) 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.10
목적 : 구제요법으로 시행한 Paclitaxel-Carboplatin의 효용과 독성을 관찰하였다. 연구 방법 : 2000년 6월부터 2003년 11월 사이에 43세에서 74세까지의 (평균연령: 57.6세) 재발성 난소암으로 진단된 10명의 환자에게 paclitaxel-carboplatin의 약물을 투여하였다. 환자들은 초 치료로서 paclitaxel과 cisplatin/carboplatin을 사용하였었다. 재발시 매 3주마다 carboplatin은 AU Objective : This study is to investigate the efficacy and toxicity of paclitaxel plus carboplatin used as a salvage therapy. Methods : Between June 2000 and November 2003, 10 patients aged 43-74 (median 55.0) with recurrent ovarian carcinoma were given co
미주신경(迷走神經)과 경혈(經穴) 주위신경(周圍神經) 차단시(遮斷時) 족삼리(足三里) 어제(魚際) 자침(刺鍼)이 위운동(胃運動)에 미치는 영향(影響)
서형주 ( Hyung Joo Seo ),김정상 ( Jeong Sang Kim ),장경선 ( Kyeong Seon Jang ),소철호 ( Cheal Ho So ),나창수 ( Chang Su Na ) 대한경락경혈학회 2000 Korean Journal of Acupuncture Vol.17 No.2
To confirm the meridian system and acupoints a pathways of functional structure, ST-36 and LU-10 were stimulated under the three conditions of nerve intact, surrounding nerve block and vagal nerve block. The results were expressed as gastric movement comparison. 1. Under nerve intact condition with ST-36 acupuncture, the stomach motility showed tendency of increase and decrease during acupuncture and following acupuncture, respectively. In the case of LU-10, the gastric activities were decreased at both circumstances. 2. When ST-36 was stimulated with sciatic nerve severed, the gastric activities were decreased at both circumstances. When LU-10 was stimulated with both median nerve and radial nerve severed, the gastric activities were decreased at both circumstances. 3. With vagal nerve severed, acupuncture of ST-36 and LU-10 caused the gastric movements to be decreased at both circumstances. 4. With ST-36 stimulated, the gastric activity showed a gradual increase with an order of nerve intact, sciatic nerve block and vagal nerve block. However, it was a gradual decrease with an order of nerve intact, radial block and vagal nerve block. Overall, ST-36 stimulation caused the stomach activity to be decreased with surrounding nerve and vagal nerve block and this was very similar in the LU-10. It is concluded that meridian system has a very close relationship with nervous system.
재발성 상피성 난소암 환자에서 Gemcitabine 단독 항암화학요법을 사용한 4예
박용주 ( Yong Joo Park ),이철민 ( Chul Min Lee ),서형주 ( Hyung Joo Seo ),이혜주 ( Hye Joo Lee ),김정선 ( Jaung Sun Kim ),고지경 ( Ji Kyung Ko ),조용균 ( Yong Kyoon Cho ),최훈 ( Hoon Choi ),김복린 ( Bok Rin Kim ),이홍균 ( Hong Ky 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.11
Interactions Between Innate Immunity Genes and Early-Life Risk Factors in Allergic Rhinitis
Seo, Ju-Hee,Kim, Hyung Young,Jung, Young-Ho,Lee, Eun,Yang, Song-I,Yu, Ho-Sung,Kim, Young-Joon,Kang, Mi-Jin,Kim, Ha-Jung,Park, Kang Seo,Kwon, Ji-Won,Kim, Byung-Ju,Kim, Hyo-Bin,Kim, Eun-Jin,Lee, Joo-Shi The Korean Academy of Asthma, Allergy and Clinical 2015 Allergy, Asthma & Immunology Research Vol.7 No.3
<P><B>Purpose</B></P><P>Allergic rhinitis (AR) is a common chronic disease. Many factors could affect the development of AR. We investigated early-life factors, such as delivery mode, feeding method, and use of antibiotics during infancy, which could affect the development of AR. In addition, how interactions between these factors and innate gene polymorphisms influence the development of AR was investigated.</P><P><B>Methods</B></P><P>A cross-sectional study of 1,828 children aged 9-12 years was conducted. Three early-life factors and AR were assessed by a questionnaire. Skin prick tests were done. Polymorphisms of <I>TLR4</I> (rs1927911) and <I>CD14</I> (rs2569190) were genotyped.</P><P><B>Results</B></P><P>Use of antibiotics during infancy increased the risk of AR (aOR [95% CI] 1.511 [1.222-2.037]) and atopic AR (aOR [95% CI], 1.565 [1.078-2.272]). There were synergistic interactions between caesarean delivery, formula feeding, and use of antibiotics in the rate of atopic AR (aOR [95% CI], 3.038 [1.256-7.347]). Additional analyses revealed that the risk for the development of AR or atopic AR subjects with the <I>TLR4</I> CC genotype were highest when all the 3 early-life factors were present (aOR [95% CI], 5.127 [1.265-20.780] for AR; 6.078 [1.499-24.649] for atopic AR). In addition, the risk for the development of AR or atopic AR in subjects with the <I>CD14</I> TT genotype were highest when all the 3 early-life factors were present (aOR [95% CI], 5.960 [1.421-15.002] for AR; 6.714 [1.440-31.312] for atopic AR).</P><P><B>Conclusions</B></P><P>Delivery mode, feeding method, and use of antibiotics during infancy appeared to have synergistic interactions in the development of AR. Gene-environment interactions between polymorphism of innate genes and early- life risk factors might affect the development of AR.</P>