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Sanz-Martin, Ignacio,Cha, Jae-Kook,Yoon, Sung-Wook,Sanz-Sanchez, Ignacio,Jung, Ui-Won Korean Academy of Periodontology 2019 Journal of Periodontal & Implant Science Vol.49 No.2
The primary aim of this systematic review was to assess the evidence on periodontal disease progression after treatment in patients receiving supportive periodontal therapy (SPT) and to identify predictors of clinical attachment level (CAL) loss. A protocol was developed to answer the following focused question: In adult patients treated for periodontitis, what is the disease progression in terms of CAL loss after surgical or non-surgical treatment? Randomized controlled clinical trials, prospective cohort studies, and longitudinal observational human studies with a minimum of 5 years of follow-up after surgical or non-surgical treatment that reported CAL and probing depth changes were selected. Seventeen publications reporting data from 14 investigations were included. Data from 964 patients with a follow-up range of 5-15 years was evaluated. When the CAL at the latest follow-up was compared to the CAL after active periodontal therapy, 10 of the included studies reported an overall mean CAL loss of ${\leq}0.5mm$, 3 studies reported a mean CAL loss of 0.5-1 mm, and 4 studies reported a mean CAL loss of >1 mm. Based on 7 publications, the percentage of sites showing a CAL loss of ${\geq}2mm$ varied from 3% to 20%, and a high percentage of sites with CAL loss was associated with poor oral hygiene, smoking, and poor compliance with SPT. The outcomes after periodontal therapy remained stable over time. Disease progression occurred in a reduced number of sites and patients, mostly associated with poor oral hygiene, poor compliance with SPT, and smoking.
Ignacio Sanz-Martín,Jae-Kook Cha,윤성욱,Ignacio Sanz-Sánchez,정의웅 대한치주과학회 2019 Journal of Periodontal & Implant Science Vol.49 No.2
The primary aim of this systematic review was to assess the evidence on periodontal disease progression after treatment in patients receiving supportive periodontal therapy (SPT) and to identify predictors of clinical attachment level (CAL) loss. A protocol was developed to answer the following focused question: In adult patients treated for periodontitis, what is the disease progression in terms of CAL loss after surgical or non-surgical treatment? Randomized controlled clinical trials, prospective cohort studies, and longitudinal observational human studies with a minimum of 5 years of follow-up after surgical or non-surgical treatment that reported CAL and probing depth changes were selected. Seventeen publications reporting data from 14 investigations were included. Data from 964 patients with a follow-up range of 5–15 years was evaluated. When the CAL at the latest follow-up was compared to the CAL after active periodontal therapy, 10 of the included studies reported an overall mean CAL loss of ≤0.5 mm, 3 studies reported a mean CAL loss of 0.5–1 mm, and 4 studies reported a mean CAL loss of >1 mm. Based on 7 publications, the percentage of sites showing a CAL loss of ≥2 mm varied from 3% to 20%, and a high percentage of sites with CAL loss was associated with poor oral hygiene, smoking, and poor compliance with SPT. The outcomes after periodontal therapy remained stable over time. Disease progression occurred in a reduced number of sites and patients, mostly associated with poor oral hygiene, poor compliance with SPT, and smoking.
Key Legal Issues Surrounding Smart Contract Applications
Pablo Sanz Bayón 한국법제연구원 2019 KLRI journal of law and legislation Vol.9 No.1
The aim of this work is to delve into some key legal issues surrounding Smart Contract applications. In the first and second parts, this paper defines the concept of Smart Contract and how it applies within the blockchain ecosystem. In the third part, this work exposes the functioning of this digital technology and the main advantage that it implies for solving the crucial issues of execution and breach of contracts. In the fourth section, this paper analyzes a set of problematic aspects that arise around Smart Contracts such as the scope and delimitation of them or the validity and certification of blockchain transactions. It also analyzes different issues related to the design of a legislative policy that addresses the design of a supranational and harmonized legal framework.
A. Sanz-Martínez,J. Lasobras,J. Soler,J. Herguido,M. Menéndez 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.113 No.-
Methanol to Gasoline (MTG) process transforms methanol to hydrocarbons within the boiling point rangeof gasoline. The result is a wide spectrum of products (olefins, paraffins, aromatics and naphthenics,among others), with the total conversion of methanol to hydrocarbons and water. Catalyst deactivationby coke is a main problem in this process. This work aims to determine the feasibility of carrying out theproduction of gasoline from methanol in a two-zone fluidized bed reactor (TZFBR). The hypothesis is thatthe formation of carbonaceous deposits (coke) on the catalyst particles can be counteracted by its combustionin the regeneration zone that this novel reactor presents, thus achieving stable and continuousoperation. In this way, both processes (reaction and regeneration) would be being carried out simultaneouslyin the same reactor (process intensification). The comparison of results between a conventional fluidizedbed reactor and a TZFBR shows that the second one actually provides a better stability over time.
When we are the violent: The Chechen Islamist guerrillas' discourse on their own armed actions
Adrián Tarín Sanz 한양대학교 아태지역연구센터 2017 Journal of Eurasian Studies Vol.8 No.2
Over the last decades, the strategic profile of the discourse with which wars are narrated has been reinforced. This discourse has also varied in the light of a recent – and alleged – peace culture permeating Western societies. Whereas the war discourse in Russia during the Second Russian-Chechen War has been widely studied, this has not been the case of the rhetoric of the Chechen Islamist guerrillas. The aim of this paper is to contribute to bridging this gap in the academic literature on the North Caucasus, employing to this end a critical discourse analysis (CDA) of a selection of texts posted by the Kavkaz Center (KC) news agency. On the basis of this analysis, it can be concluded that one of the main discursive strategies revolved around the construction of an “us” embodying the Chechen victims of the initial aggression in a conflict provoked by the Russian “other”.
Borque-Fernando Ángel,Estrada-Domínguez Fernando,Esteban Luis Mariano,Gil-Sanz María Jesús,Sanz Gerardo 대한남성과학회 2023 The World Journal of Men's Health Vol.41 No.1
Purpose: To analyze the variability, associated actors, and the design of nomograms for individualized testosterone recovery after cessation of androgen deprivation therapy (ADT). Materials and Methods: A longitudinal study was carried out with 208 patients in the period 2003 to 2019. Castrated and normogonadic testosterone levels were defined as 0.5 and 3.5 ng/mL, respectively. The cumulative incidence curve described the recovery of testosterone. Univariate and multivariate analyzes were performed to predict testosterone recovery with can-didate prognostic factors prostate-specific antigen at diagnosis, clinical stage, Gleason score from biopsy, age at cessation of ADT, duration of ADT, primary therapy and use of LHRH (luteinizing hormone-releasing hormone) agonists. Results: The median follow-up duration in the study was 80 months (interquartile range, 49–99 mo). Twenty-five percent and 81% of patients did not recover the castrate and normogonadic levels, respectively. Duration of ADT and age at ADT ces-sation were significant predictors of testosterone recovery. We built two nomograms for testosterone recovery at 12, 24, 36, and 60 months. The castration recovery model had good calibration. The C-index was 0.677, with area under the receiver operating characteristic curve (AUC-ROC) of 0.736, 0.783, 0.782, and 0.780 at 12, 24, 36, and 60 months, respectively. The normogonadic recovery model overestimated the higher values of probability of recovery. The C index was 0.683, with AUC values of 0.812, 0.711, 0.708 and 0.693 at 12, 24, 36, and 60 months, respectively. Conclusions: Depending on the age of the patient and the length of treatment, clinicians may stop ADT and the castrated tes-tosterone level will be maintained or, if the course of treatment has been short, we can estimate if it will return to normogo-nadic levels.