교정용 미니 임플랜트의 cutting flute의 길이 및 형태에 따른 식립 및 제거 토크의 비교

윤순동,임성훈 대한치과교정학회 2009 대한치과교정학회지 Vol.39 No.2

Objective: The purpose of this study was to evaluate the effect of length and shape of cutting flute on mechanical properties of orthodontic mini-implants. Methods: Three types of mini-implants with different flute patterns (Type A with 2.6 mm long flute, Type B with 3.9 mm long and straight flute, Type C with 3.9 mm long and helical flute) were inserted into the biomechanical test blocks (Sawbones Inc., USA) with 2 mm and 4 mm cortical bone thicknesses to test insertion and removal torque. Results: In 4 mm cortical bone thickness, Type C mini-implants showed highest maximum insertion torque, then Type A and Type B in order. Type C also showed shortest total insertion time and highest maximum removal torque, but Type A and B didn't showed statistically significant difference in insertion time and removal torque. In 2 mm cortical bone thickness, there were no significant difference in total insertion time and maximum removal torque in three types of mini-implants, but maximum insertion torque of Type A was higher than two other Types of mini-implants. Conclusions: Consideration about length and shape of cutting flute of mini-implant is also required when the placement site has thick cortical bone. 본 연구는 self-tapping screw의 특징적 구조인 cutting flute의 길이 및 형태 변화에 따른 미니 임플랜트의 식립 및 제거 토크를 비교해보기 위해 시행되었다. 외경, 내경, 길이 및 pitch 등 다른 조건이 모두 동일하고 cutting flute의 형태만 다른 세 종류의 미니 임플랜트를 사용하였다(A군; 2.6 mm 길이의 flute가 형성된 그룹, B군; 3.9 mm의 길이이면서 직선형의 flute를 갖는 그룹, C군; 3.9 mm의 길이이면서 나선형의 flute를 갖는 그룹). 골밀도를 균일하게 하기 위해 실험용 인공골(Sawbones Inc., USA)을 사용하였으며, 수직력 및 회전속도를 일정하게 하기 위해 구동식 토크 시험기를 이용하였다. 그 결과 다음과 같은 결론을 얻었다. 총 삽입 시간은 2 mm 두께의 피질골 시편에서는 세 군간에 차이를 보이지 않으나, 4 mm 두께의 피질골 시편에서는 C군 > B군 > A군 순으로 짧은 삽입 시간을 보였다. 최대 삽입 토크는 2 mm 두께의 시편에서는 A군이 다른 두 군에 비해 높은 값을 보이나, 4 mm 두께의 피질골 시편에서는 C군 > A군 > B군 순으로 높은 값을 보였다. 최대 제거 토크는 2 mm 두께의 피질골 시편에서는 세 군 사이에 차이가 없으나, 4 mm 두께의 피질골 시편에서는 C군이 다른 두 군에 비해 높은 값을 보여주었다. 이상의 결과로 보아 피질골이 두꺼운 부위에 미니 임플랜트를 식립할 경우 cutting flute의 길이 및 형태 또한 고려하여 미니 임플랜트를 선택하는 것이 바람직하다.

돼지에서 정맥, 근육 그리고 경구 투여시의 enrofloxacin의 약물동태학

윤효인,김무열,박승춘,조준형,박병권,이내경,노상석,장범수,신광순,조명행 충남대학교 수의과대학 동물의과학연구소 1996 動物醫科學硏究誌 Vol.4 No.-

In order to characterize pharmacokinetic profiles according to route of a new enrofloxacin salt form (Enrotil®), it was given to 4 healthy pigs via oral (p.o.), intramuscular (i.m.) or intravenous (i.v.) administrations at a dose rate of 5 ㎎/㎏ body weight. Enrofloxacin (ENFX) in serum was detected by bioassay using E. coli BE1186 as a test organism. The biological elimination half-lives (t_1/2(β)) of ENFX were 6.76±0.99 h (i.v.), 7.16±2.30 h (i.m.) and 11.45±3.90 h (p.o.), Volume of distribution (Vd) of enrofloxacin was 2.20±0.31 L/㎏ (i.v.), 2.52±0.60 L/㎏ (i.m.) and 1.88±0.33 L/㎏ (i.m.). Mean residence time (MRT) was 8.77±1.26 h after i.v. injection and the maximal concentration time (Tmax) following p.o. and i.m. administration was 0.76±0.09 h and 0.60±0.12 h, indicating a rapid absorption from these routes. Bioavailibility (F) was calculated as 64.1% for p.o. administration and 59.71% for i.m. injections. In summary, the newly formulated enrofloxacin salt form has shown a high water solubility, rapid absorption and large tissue distribution, suggesting a potential antibacterials for oral application on a large scale in veterinary sectors.

전격성 경과를 취한 만성 호산구성 폐렴 환자 1예

윤호상,진춘조,유광하,이상엽,이수인,정상만,김선두,이순제,이길도,전혜정 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

Chronic eosinophilic pneumonia(CEP) is a rare disease of unknown etiology characterized by chronic infiltration of the lung with eosinophils. It presents with profound systemic symptoms comprising fever, night sweats, weight loss, dyspnea and blood eosinophilia with nonsegmental air-space consolidation confined to the outer third of the lung, the "photographic negative of pulmonary edema". Histopathologic features of chronic eosinophilic pneumonia are intraalveolar and interstitial infiltrations with eosinophils, histiocytes, giant cells, scattered lymphocytes and plasma cells. Glucocorticoid therapy cause prompt resolution of symptoms as well as disappearans of blood eosinophils, elevated serum Ig E levels and the roentgenographic lesions. Infrequent radiographic findings include nodular infiltrates, consolidations, cavitations, atelectasis and pleural effusions. Deaths from CEP although rare, have been reported, but the majorities of CEP have benign courses and do not need a therapy with ventilator. We report a case of chronic eosinophilic pneumonia, which had a sudden course associated with diffuse pneumonic consolidations on the both lung and bilateral pleural effusion.

國民學校 兒童의 姿勢計測에 對한 硏究

尹南植,韓成一,成丁順 梨花女子大學校 韓國生活科學硏究院 1977 韓國生活科學硏究院 論叢 Vol.18 No.-

국민학교 어린이들의 자세의 諸特性을 分析하여 學校現場에서의 자세교육의 지도자료를 구하는데 연구 목적이 있다. 서울, 경기지방의 남녀 어린이 240명에 대하여 척주 만곡도, 下肢의 상태 등을 계측하여 分析檢討한 結果를 다음과 같이 要約할 수 있다. (1) 연구대상자의 신체 형태의 특징은 細長型인데, 약 28%의 어린이는 전에 병을 앓은 경험이 있고, 50∼60%의 영양 불량아가 있다. (2) 자세에 미치는 환경 요인은 不實한 傾向이 있지만 자세 지도나 자세에 대한 관심도는 비교적 높다. (3) 立位자세의 표준 前傾度는 남자 4˚∼+5˚, 여자 -3˚∼+3˚이다. (4) 흉추부의 표준 만곡도는 남자 3˚∼12˚, 여자 4˚∼12˚이다. (5) 표준 상배 후만각은 남자 155˚∼168˚, 여자 152˚∼166˚이고, 표준 요부전막각은 남녀 모두 152˚∼168˚이다. (6) o脚은 전체 어린이의 7%이고 x脚은 3%를 차지하고 있다. The purpose of this study was to obtain the materials on the posture education at school. The subjects chosen for this study were 240 children from the first to the sixth grades at the elementary schools located in Seoul and Kyong-Gi Province. The children were interviewed each to examine the posture structure, were measured the degrees of vertebrae curvatures and the structure of the lower limbs by the Cureton's conformatuer to find the characteristics of the posture. The results were: (1) The children were near to the type of ectomorph posture. About 28% of the children had previously suffered the serious diseases. The children of unbalanced diet were from 50% to 60% of the total number. (2) 45% of the children used the desks and chairs when they study, and 70% of them had their desks and chairs unfit to their body structures. (3) Under these unfavorable circumstances, the children showed, however, the higher enthusiasm for the posture education which is encouraging. (4) The average Angle ∠α of forward curvature in standing position was about -4˚∼+5˚ among boys and -3˚∼43˚ among girls. (5) The average angle ∠a' of verabrae curvature of the thoracic was 3˚∼12˚ among sboy and 4˚∼12˚ among girls. (6) The male with Kyphosis (hunch back) was about 155˚∼168˚, the female was 152˚∼166˚. The male and female with lordossis of lumber curvature was 152˚∼168˚. (7) The children of bowlegs (O type) and those of knock knees (x type) were 3% of the whole.

자궁선근증의 고찰

조환성,이해혁,정성윤,김성욱,이순곤,남계현,이임순,이권해 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Objective: This study was designed to estimate the frequency and risk factor for edenomyosis Methods: The clinical records of 623 women undergoing hysterectomy were retrieved in the Department of Obstetrics and Gynecology, Soonchunhyang University Hospital, during 5 years, from Jan. 1995 to Dec. 1999. Results: The following result were obtained. 1. Adenomyosis was found in 247 of 623 patients(39.6%) 2. The highest incidence was 40-49 years of age group, an incidence of 46.6% and mean age was 44.7 years. 3. Adenomyosis was more frequently observed in parous women than non-parous women, such as 93.1% and 6.9%, respectively. 4. Dysmenorrhea, metrorrhagia, pelvic pain and vaginal bleeding were common symptom of adenomyosis, an incidence of 28.7%, 19.0%, 18.2% and 16.2%, respectively. 5. Myoma was the most combined disease in adenomyosis, showing the incidence of 54.7%. 6. Grossly, the size of uterus was enlarged more than 10 weeks gestational size in adenomyosis, an incidence of 61.9%. 7. Preoperative diagnostic accuracy of adenomyosis was 6.9%. Conclusion: The results show that deeply understanding of the common symptoms and epidemiology of adenomyosis improve the preoperative diagnostic accuracy.

비소세포 폐암 환자의 이차 치료로서 Gemcitabine과 Vinorelbine 혼합 요법의 효과

장필순,강현모,이정은,권선중,안진영,이연선,정성수,김주옥,김선영 충남대학교 암연구소 2006 암연구소 업적집 Vol.5 No.-

Background : Both gemcitabine and vinorelbine are effective anticancer drugs with mild toxicity on non-small cell lung cancer, and monotherapy of these drugs are effective as a second-line chemotherapy. The aim of this trial was to assess the response and toxicity of a combination of gemcitabine and vinorelbine in patients of previously treated for non-small cell lung cancer. Materials and Methods : 24 patients, initial stage III A/B,IV and previously treated with platinium and taxane based regimens, were enrolled from June 2000 to March 2004. The regimens consisted of vinorelbine 25mg/㎡ followed by an infusion of gemcitabine 1000mg/㎡ on day 1 and day 8 every three weeks. This course was repeated more than twice. Results : Twenty-four patients were analyzed for the response, survival rate, and toxicities. The overall response was 17% with a complete remission rate of 4%. The median time-to progression (TTP) was 3.1 months (95%, CI l-10months), and the survival time was 8.2 months (95%, CI 1-23 months). The grade 3/4 toxicities encountered were neutropenia (12.5%), anemia (0%), thrombocytopenia (0%). Non-hematological 3/4 toxicities were not observed. Conclusion : A combination of gemcitabine and vinorelbine in patients previously treated for non-small cell lung cancer provides a relatively good response rate, and a low toxicity profile. However, further study will be needed to confirm its effectiveness. (Tuberc Respir Dis 2005; 58: 344-351)

Carbosulfan의 피부자극성, 안점막 자극성 및 피부감작성등의 알러지성 효과에 관한 연구

이상훈,이동연,백경진,김태원,정두순,임종환,김명석,박병권,윤효인 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

Many studies have been published on the human health effects of carbosulfan toxicity. Carbosulfan used as an insecticide can produce an irritating and allergenic effect when acting on the skin. In this study, a sensitization test on albino guinea pigs and intradermal reactivity and occular irritation test on albino rabbits were carried out with carbosulfan. Signs of acute skin inflammation appeared along with the clinical symptom of chronic dermatosis caused by the solution irritating characteristics. Moreover, carbosulfan showed severe eye irritation with conjuctival redness and severe opacity on cornea. Preventive measures should involve workers' obligatory instructions on the noxious impact on human skin and strict observance of industrial safety rules.

다량의 하부위장관출혈이 병발된 Vibrio vulnificus 패혈증 1예

최주연,유진홍,한석원,이대훈,최민호,박순민,김연식,김선우,신완식,강문원,강성구 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.2

최근 저자들은 Vibrio vulnificus 감염에 의해 패혈증 및 이차성 피부 병변을 보인 42세의 남자 환자의 치료중 하부 위장관 출혈이 병발된 1예를 경험하였기에 보고하는 바이다. We experienced a case of Vibrop vulnificus septicemia which showed an unusual manifestation such as hematochezia. The patient was a 42-year-old man with chronic liver disease. The blood and wound culture revealed the organism. During intensive care, he suffered from massive hematochezi for several days. Colonoscopy and abdominal CT showed findings suspicious of ischemic colitis. To our knowledge, this is the first unusual case of V.vulnificus infection which showed massive lower gastrointestinal bleeding.

變斷面 I-型 曲線格子桁橋의 影響線에 관한 硏究

장병순,서상근,윤정섭 釜山大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.53 No.-

변단면 I-형 곡선격자교의 최대부재력을 해석하기 위해 본연구에서는 Vlasov의 기초미분방정식을 이용하고 이를 유한차분법을 이용하여 변단면의 휨모멘트, 전단력, 순수비틂모멘트, ��綢낯霽璇� 바이모멘트의 영향선을 구하여 제시하였고 이를 이용해 최대부재력이 생기는 점에서의 단위하중의 작용위치를 구하였다. 실제 교량해석에 있어 본논문의 결과를 이용하면 부재의 부재력을 쉽게 구할수 있을 것이다. The general behavior of curved girder considering the warping effects is formulated by series of differential equations postulated by Vlasov. In order to deternine the maximum bending moment, the maximum shear force, the maximum pure torsion, the maximum warping torsion, and the maximum bimoment for the curved girder grid bridges, it is important ot find the location of live load applied to the curved girder grid bridges. The fundamental differential equation concerning the behaviour with warping effects for the curved girder is developed by Vlasov. Also, shear force, bending moment, pure torsion, warping torsion, and bimoment for curved I-girder bridge are analyzed by the finite difference method. In this paper, the influence line of shear force, bending moment, pure torsion, warping torsion, and bimoment due to unit vertical load and unit torsional moment for curved I-girder grid bridges with variable cross section are obtained by using the finite difference method and compared with respectively.

반복성 단늑골 다지 증후군 1예

방성윤,최규연,박은희,강미경,김미경,이정재,이임순 순천향의학연구소 2005 Journal of Soonchunhyang Medical Science Vol.11 No.1

Short-rib polydactyly syndromes(SRPS) comprise a group of rare, generally lethal skeletal dysplasias. This group is manifested by short-limb short stature, short ribs with thorasic hypoplasia, and polydactyly. This heterogenous group of recessively inherited disorder has distinct imaging findings and ancillary findings on both pre-and postnatal assessments may enable individual cases to be classified into one of four subtypes : SRPS Ⅰ(Saldino-Noonan); SRPS Ⅱ (Majewski); SRPS Ⅲ (Verma-Naumoff); and SRPS Ⅳ (Beemer-Langer)1,2,3). All forms of the SRPS described to date are thought to be inherited in an autosomal recessive manner. There are difficulties in the clssification of these disorders because of the frequent overlap. We experienced one case of recurrent short-rib polydactyly syndrome and presented with review of literature.