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췌장암에서 Cyclooxygenase - 2 발현의 역할
김은경,이용욱,이규택,최규완,박동일,백승운,이준행,이종균,고광철,이풍렬,이종철,김재준,김완선,공구 대한소화기학회 2001 대한소화기학회지 Vol.38 No.3
Background/Aims: Accumulating evidence suggests that the use of NSAID may reduce the incidence of colorectal cancer. The likely mechanisms of these effects by NSAID is cyclooxygenase-2 (COX-2)-related inhibition of tumor proliferation and induction of apoptosis. The aim of our study was to examine possible roles and clinical significance of COX-2 expression in pancreatic cancer. Methods: Seventy-two pancreatic adenocarcinoma tissue specimens were obtained from surgical resection. After the immunohistochemical staining of the specimens, we examined proliferation activity (assayed by Ki-67 expression), apoptosis (by TUNEL stain), and microvessel density (by CD34 expression). We also investigated the relationship between the immunohistochemical expression of COX-2 and various clinicopathological characteristics. Results: The COX-2 positive rate in pancreatic epithelial cells was 41.7%. Proliferation index (PI) was significant higher in COX-2 positive specimens comparing to negative specimen (p=0.015) and the increase in intensity of COX-2 expression correlated with increasing PI (p=0.036). Apoptotic index (AI) was significantly higher in positivee COX-2 expression than in negative expression (p=0.044), but there was no significant difference in AI/PI between the COX-2 positive and negative specimens (p=0.44). The expression of COX-2 protein did not correlate with microvessel density, sex, age, differentiation, tumor size, stage, metastasis or patients survival. Conclusions: The expression of COX-2 enzyme in pancreatic cancer contributes to tumor proliferation, but is not related to apoptosis, angiogenesis or clinical characteristics. Further study is needed to examine the clinical usefulness of NSAID and COX-2 selective inhibitors.
Effects of PASS Theory on Aged Chinese EFL Learners’ Reading Comprehension Ability
Yipu Gong(Yipu Gong),Jongbok Lee(Jongbok Lee) 한국영어어문교육학회 2023 영어어문교육 Vol.29 No.1
This study investigates the English learning conditions of aged Chinese EFL learners including their reading comprehension ability through a cognitive approach-PASS theory. A quantitative-dominated research method is adopted in the study. After a 15- week semester, a significant distinction in both posttest (reading comprehension score, t = 3.39, p = .000) and retention test (reading comprehension scores, t = 4.62, p = .000) indicates that the cognitive teaching approach through PASS model outperforms the traditional teaching approach. As another independent variable, the quantity of Chinese characters used in English learning only sees a significant difference for the population according to reading comprehension scores in the posttest results (posttest, F = 4.56, p = .038 & retention test, F = 1.04, p =. 312). Besides, during the retention test, the Chinese characters quantity factor showed significant effect only on the experiment group’s English reading comprehension results. Through this study, an effective cognitive pedagogy for EFL aged learners has been claimed to public. Admittedly, there is still limitation. The investigation of corresponding details of the dynamic changes of the aged EFL learners’ cognitive process is insufficient. This limitation can be lifted up in future studies and transformed into further academic extension as well.
Sensitivity of surface characteristics on the simulation of wind-blown-dust source in North America
Park, S.H.,Gong, S.L.,Gong, W.,Makar, P.A.,Moran, M.D.,Stroud, C.A.,Zhang, J. Pergamon Press ; Elsevier [distribution] 2009 Atmospheric environment Vol.43 No.19
Recently, a wind-blown-dust-emission module has been built based on a state-of-the-art wind erosion theory and evaluated in a regional air-quality model to simulate a North American dust storm episode in April 2001 (see Park, S.H., Gong, S.L., Zhao, T.L., Vet, R.J., Bouchet, V.S., Gong, W., Makar, P.A., Moran, M.D., Stroud, C., Zhang, J. 2007. Simulation of entrainment and transport of dust particles within North America in April 2001 (''Red Dust episode''). J. Geophys. Res. 112, D20209, doi:10.1029/2007JD008443). A satisfactorily detailed assessment of that module, however, was not possible because of a lack of information on some module inputs, especially soil moisture content. In this paper, the wind-blown-dust emission was evaluated for two additional dust storms using improved soil moisture inputs. The surface characteristics of the wind-blown-dust source areas in southwestern North America were also investigated, focusing on their implications for wind-blown-dust emissions. The improved soil moisture inputs enabled the sensitivity of other important surface characteristics, the soil grain size distribution and the land-cover, to dust emission to be investigated with more confidence. Simulations of the two 2003 dust storm episodes suggested that wind-blown-dust emissions from the desert areas in southwestern North America are dominated by emissions from dry playas covered with accumulated alluvial deposits whose particle size is much smaller than usual desert sands. As well, the source areas in the northwestern Texas region were indicated to be not desert but rather agricultural lands that were ''activated'' as a wind-blown-dust sources after harvest. This finding calls for revisions to the current wind-blown-dust-emission module, in which ''desert'' is designated to be the only land-cover category that can emit wind-blown dust.
The Innovative Application of Surface Texture in Fashion and Textile Design
( Gong Lin ),( Jooyoung Shin ) 한국의류산업학회 2013 한국의류산업학회지 Vol.15 No.3
This study focuses on ‘texture’ as one of the most important fashion and textile design elements; in addition, it proposes various applications of it. Surface texture is indispensable in fashion and textile design that also factors heavily into innovative creations. Along with technological advances in the fashion industry, surface texture has derived many new and attractive features that provide more opportunities for designers to show various design concepts. Rather than the surface quality of fabrics, surface texture in fashion design creates its identity through a manipulation of materials- an application that tends to be primarily for visual effects without being restricted to decorative purposes. The status and significance of surface texture in various creative fields is explored and the evolution of surface texture is traced by analyzing a number of fashion design cases with representative surface textures. The latest feature of surface texture in fashion and textile design is identified to establish a new classification of surface texture with five groups and technical suggestions. This study provides a theoretical basis for this field of study and a new framework that can be employed in the development of surface textures that use innovative techniques as well as the future application of newly-developed textures.
Gong, Wontae International Academy of Physical Therapy Research 2018 Journal of International Academy of Physical Ther Vol.9 No.1
The purpose of this study is to investigate the effect of pelvic, Lumbar spine and Cervical spine manipulation on the joint position sense in normal adults. Thirty normal adults were divided into an experimental group of 15 subjects and a control group of 15 subjects. The experimental group was treated with pelvic, Lumbar spine and Cervical spine manipulation with massage, whereas the control group received only massage. Both groups were evaluated in terms of joint position errors (JPEs) using a digital dual clinometer before and after the experiment. The comparison of the JPEs of the experimental group and the control group before and after the experiment showed that the experimental group's cervical spine results were significantly different in the flexion, left lateral flexion, and right rotation (p < .05) and lumbar spine results were significantly different in the flexion and extension (p < .05), but the control group's results were not statistically significant in all items (p > .05). The pelvic, lumbar spine and cervical spine manipulation makes an effect on the joint position sense in normal adults. The findings of this study suggest that the pelvis, lumbar spine and cervical spine manipulation improve the motor ability in people with low joint position sense.
Gong, Tae-Kyung,Moon, Hyun-Joo,Kim, Daeil The Korean Institute of Electrical and Electronic 2016 Transactions on Electrical and Electronic Material Vol.17 No.2
ZnSnO<sub>3</sub> (ZTO)/Ag/ ZnSnO<sub>3</sub> (ZTO) trilayer films were prepared on glass substrates by radio frequency (RF) and direct current (DC) magnetron sputtering. The electrical resistivity and optical transmittance of the films were investigated as a function of the Ag interlayer thickness. ZTO films with a 15 nm thick Ag interlayer show the highest average visible transmittance (83.2%) in the visible range. In this study, the highest figure of merit (2.1×10<sup>−2</sup> Ω cm) is obtained with the ZTO 50 nm/Ag 15 nm/ZTO 50 nm films. The enhanced optical and electrical properties of ZTO films with a 15 nm thick Ag interlayer are attributed to the crystallization of the Ag interlayer, as supported by the distinct XRD pattern of the Ag (111) peaks. From the observed results, higher optical and electrical performance of the ZTO film with a 15 nm thick Ag interlayer seems to make a promising alternative to conventional transparent conductive ITO films.
Distribution and Abundance of Flying Squid Caught by Korean Gill - nets in the North Pacific
Gong, Yeong,Kim, Yeong Seung,Kim, Soon Song,Hur, Young Hee 한국수산학회 1984 한국수산과학회지 Vol.17 No.6
The seasonal distribution and abudance of flying squid ommastrephes bartrami (LeSueur) in the North Pacific (Lat. 34˚-46˚N, Long. 141˚E-161˚W) were studied by means of the dorsal mantle length data, surface temperature data. and catch and effort data of the Korean drift gill net fishery (May 1983-January 1984). According to the monthly abundance indices and mantle length compositions, the fishing grounds are separated into two regions, one in the central North Pacific east of Long. 170˚E from May to July and the other in the northwestern Pacific west of Long. 160˚ E from August to January. Relatively higher catches and abundance indices for flying squid occurred from July to November with a peak in August and September. Flying squid with high density were found in the southern periphery of the subarctic boundary in the central North Pacific region from May to July and in the Transitional and Subarctic domain in the north-western Pacific region from August to December. In the length compositions of flying squid, dominaut modes were at 40 ㎝ in the central North Pacific from June to July and at 30 ㎝ in the northwestern Pacific from Septemer to December. Accordingly, it was recognized that the large sized flying squid moved to the central Pacific region earlier than the small sized group from June to July. The range of surface temperatures for commercial fishing of flying squid was 9-22℃. The water temperature for the best fishing ranged from 15-16℃ in May though July and from 13-19℃ in August through January. The migration models for flying squid were hypothesized based on the monthly distributions of abundance indices, monthly mantle length compositions by statistical block (Lat. 2˚×5˚Long.) and the hydrographic of the North Pacific,