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      • Effect of Fading on Performance of VANET in Realistic Scenarios Using NCTUns6.0

        Richa Sharma,Jyoteesh Malhotra,Komal Sharma 보안공학연구지원센터 2015 International Journal of Future Generation Communi Vol.8 No.1

        Road safety and increasing transport efficiency are the important goals for intelligent transport system (ITS). Vehicular Ad hoc Network is such a network which can help to achieve these goals. VANET routing is a crucial task for reliable communication among vehicles. The impact of fading on network throughput and packet drop is explored in this paper. Interesting results show the performance evaluation of without fading environment and Rayleigh fading in different scenarios. NCTUns 6.0 (National Chiao Tung University Network Simulator) is used to justify our results that is a GUI based open source platform for vehicular Ad-Hoc network. Various performance issues are also surveyed with the help of this simulator.

      • Character based ASCII Encryption & Decryption on Cloud System

        Richa Sharma,K. K. Parashar,Jitendra Singh Sengar 보안공학연구지원센터 2016 International Journal of Database Theory and Appli Vol.9 No.5

        This paper proposed a algorithm for automatic key generation which generate from an integer value to create more secure communication over cloud architecture. Character based ASCII encryption scheme is used to satisfy the current requirement to establish secure communication. In this work we have a byte level security at each level of data transmission. It helps to create batter security to perform encryption & decryption over cloud infrastructure i.e., from this work we have technique through which we generate private key which help to establish secure communication between two or more node while they are communicating over cloud system.

      • SCISCIESCOPUS

        Anomalously Large Reactivity of Single Graphene Layers and Edges toward Electron Transfer Chemistries

        Sharma, Richa,Baik, Joon Hyun,Perera, Chrisantha J.,Strano, Michael S. American Chemical Society 2010 NANO LETTERS Vol.10 No.2

        <P>The reactivity of graphene and its various multilayers toward electron transfer chemistries with 4-nitrobenzene diazonium tetrafluoroborate is probed by Raman spectroscopy after reaction on-chip. Single graphene sheets are found to be almost 10 times more reactive than bi- or multilayers of graphene according to the relative disorder (<I>D</I>) peak in the Raman spectrum examined before and after chemical reaction in water. A model whereby electron puddles that shift the Dirac point locally to values below the Fermi level is consistent with the reactivity difference. Because the chemistry at the graphene edge is important for controlling its electronic properties, particularly in ribbon form, we have developed a spectroscopic test to examine the relative reactivity of graphene edges versus the bulk. We show, for the first time, that the reactivity of edges is at least two times higher than the reactivity of the bulk single graphene sheet, as supported by electron transfer theory. These differences in electron transfer rates may be important for selecting and manipulating graphitic materials on-chip.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/nalefd/2010/nalefd.2010.10.issue-2/nl902741x/production/images/medium/nl-2009-02741x_0009.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nl902741x'>ACS Electronic Supporting Info</A></P>

      • Reliability analysis of an embedded system with multiple vacations and standby

        Richa Sharma,Manju Kaushik,Gireesh Kumar 한국신뢰성학회 2015 International Journal of Reliability and Applicati Vol.16 No.1

        This investigation deals with reliability and sensitivity analysis of a repairable embedded system with standby wherein repairman takes multiple vacations. The hardware system consists of ‘M’ operating and ‘S’ standby components. The repairman can leave for multiple vacations of random length during its idle time. Whenever any operating unit fails, it is immediately replaced by a standby unit if available. Moreover, governing equations of an embedded system are constructed using appropriate birth-death rates. The vacation and repair time of repairman are exponentially distributed. The matrix method is used to find the steady-state probabilities of the number of failed components in the embedded system as well as other performance measures. Reliability indexes are presented. Further, numerical experiments are carried out for various system characteristics to examine the effects of different parameter. Using a special class of neuro-fuzzy systems i.e. Adaptive Network-based Fuzzy Interference Systems (ANFIS), we also approximate various performance measures. Finally, the conclusions and future research directions are provided.

      • Reliability analysis of an embedded system with multiple vacations and standby

        Sharma, Richa,Kaushik, Manju,Kumar, Gireesh The Korean Reliability Society 2015 International Journal of Reliability and Applicati Vol.16 No.1

        This investigation deals with reliability and sensitivity analysis of a repairable embedded system with standby wherein repairman takes multiple vacations. The hardware system consists of 'M' operating and 'S' standby components. The repairman can leave for multiple vacations of random length during its idle time. Whenever any operating unit fails, it is immediately replaced by a standby unit if available. Moreover, governing equations of an embedded system are constructed using appropriate birth-death rates. The vacation and repair time of repairman are exponentially distributed. The matrix method is used to find the steady-state probabilities of the number of failed components in the embedded system as well as other performance measures. Reliability indexes are presented. Further, numerical experiments are carried out for various system characteristics to examine the effects of different parameter. Using a special class of neuro-fuzzy systems i.e. Adaptive Network-based Fuzzy Interference Systems (ANFIS), we also approximate various performance measures. Finally, the conclusions and future research directions are provided.

      • KCI등재

        Evaluating the Pathway for Co-fermentation of Glucose and Xylose for Enhanced Bioethanol Production Using Flux Balance Analysis

        Richa Arora,Shuvashish Behera,Nilesh Kumar Sharma,Sachin Kumar 한국생물공학회 2019 Biotechnology and Bioprocess Engineering Vol.24 No.6

        Two novel thermotolerant yeasts, Kluyveromyces marxianus NIRE-K1.1 and Kluyveromyces marxianus NIRE-K3.1, evolutionarily adapted for fermentation of glucose and xylose were analyzed for their metabolic fluxes with an objective of maximum ethanol production. Metabolic fluxes were analyzed for these thermotolerant yeasts by co-fermenting glucose/xylose mixture in two different ratios (1:1 and 4:1). Flux balance analysis revealed the active role of pentose phosphate pathway for effective xylose utilization in both yeasts. A comparison between co-fermentation of glucose/xylose mixtures in the ratio of 1:1 and 4:1 (g/L) reveals that the flux from glucose-6- phosphate to ribulose-5-phosphate was approximately 2.56-fold and 3.75-fold higher in 1:1 mixture in K. marxianus NIRE-K1.1 and K. marxianus NIRE-K3.1, respectively. Overall, flux towards pyruvate (for ethanol production) was found to be higher in both glucose/xylose mixtures 1:1 (1.87%) and 4:1 (0.89%) for K. marxianus NIRE-K3.1 than K. marxianus NIRE-K1.1. Tricarboxylic Acid (TCA) cycle was also found to be incomplete for both the isolates which signify that most of the available substrates were utilized for ethanol production rather than biomass formation. Moreover, it was also observed that in both, the ethanol yields were found to be higher in case of K. marxianus NIRE-K3.1 than K. marxianus NIRE-K1.1, however, xylose uptake rates were higher in the later as compared to the former. Thus, this study concludes with the capable potential of both the yeasts for the production of bioethanol from glucose/xylose mixtures with higher yield and is highly correlated to the relative concentration of both xylose and glucose in a mixture.

      • SCISCIESCOPUS

        Rhodium-Catalyzed [3 + 2] Annulation of Cyclic <i>N</i>-Acyl Ketimines with Activated Olefins: Anticancer Activity of Spiroisoindolinones

        Sharma, Satyasheel,Oh, Yongguk,Mishra, Neeraj Kumar,De, Umasankar,Jo, Hyeim,Sachan, Richa,Kim, Hyung Sik,Jung, Young Hoon,Kim, In Su American Chemical Society 2017 Journal of organic chemistry Vol.82 No.7

        <P>The rhodium(III)-catalyzed redox-neutral coupling reaction of N-acyl ketimines generated in situ from 3-hydro-xyisoindolinones with various activated olefins is described. This approach leads to the synthesis of bioactive spiroisoindolinone derivatives in moderate to high yields. In the case of internal olefins such as maleimides, maleates, fumarates, and cinnamates, spiroindanes were obtained by the [3 + 2] annulations reaction. In sharp contrast, acrylates and quinones displayed the beta-H elimination followed, by Prins-type cyclization furnishing spiroindenes. The synthetic compounds were evaluated for in vitro anticancer activity against androgen-sensitive human prostate adenocarcinoma cells (LNCaP), human prostate adenocarcinoma cells (DU145), human endometrial adenocarcinoma cells (Ichikawa), human breast cancer cell (MCF-7), and triple negative human breast cancer cells (MDA-MB-231). Notably, quinone-containing spiroindenes displayed potent anticancer activity about 2- to 3-fold stronger than that of anticancer agent doxorubicin.</P>

      • KCI등재후보

        Fetomaternal outcomes in pregnant women with congenital heart disease: a comparative analysis from an apex institute

        Soniya Dhiman,Aparna Sharma,Akanksha Gupta,Richa Vatsa,Juhi Bharti,Vidushi Kulshrestha,Satyavir Yadav,Vatsla Dadhwal,Neena Malhotra 대한산부인과학회 2024 Obstetrics & Gynecology Science Vol.67 No.2

        Objective With advancements in cardiac surgical interventions during infancy and childhood, the incidence of maternal congenital heart disease (CHD) is increasing. This retrospective study compared fetal and cardiac outcomes in women with and without CHD, along with a sub-analysis between cyanotic versus non-cyanotic defects and operated versus non-operated cases.Methods A 10-year data were retrospectively collected from pregnant women with CHD and a 1:1 ratio of pregnant women without any heart disease. Adverse fetal and cardiac outcomes were noted in both groups. Statistical significance was set at <i>P</i><0.05.Results A total of 86 pregnant women with CHD were studied, with atrial septal defects (29.06%) being the most common. Out of 86 participants, 27 (31.39%) had cyanotic CHD. Around 55% of cases were already operated on for their cardiac defects. Among cardiovascular complications, 5.8% suffered from heart failure, 7.0% had pulmonary arterial hypertension, 8.1% presented in New York Heart Association functional class IV, 9.3% had a need for intensive care unit admission, and one experienced maternal mortality. Adverse fetal outcomes, including operative vaginal delivery, mean duration of hospital stay, fetal growth restriction, preterm birth (<37 weeks), low birth weight (<2,500 g), 5-minute APGAR score <7, and neonatal intensive care unit admissions, were significantly higher in women with CHD than in women without heart disease.Conclusion Women with CHD have a higher risk of adverse fetal and cardiac outcomes. The outcome can be improved with proper pre-conceptional optimization of the cardiac condition, good antenatal care, and multidisciplinary team management. Objective With advancements in cardiac surgical interventions during infancy and childhood, the incidence of maternal congenital heart disease (CHD) is increasing. This retrospective study compared fetal and cardiac outcomes in women with and without CHD, along with a sub-analysis between cyanotic versus non-cyanotic defects and operated versus non-operated cases. Methods A 10-year data were retrospectively collected from pregnant women with CHD and a 1:1 ratio of pregnant women without any heart disease. Adverse fetal and cardiac outcomes were noted in both groups. Statistical significance was set at P<0.05. Results A total of 86 pregnant women with CHD were studied, with atrial septal defects (29.06%) being the most common. Out of 86 participants, 27 (31.39%) had cyanotic CHD. Around 55% of cases were already operated on for their cardiac defects. Among cardiovascular complications, 5.8% suffered from heart failure, 7.0% had pulmonary arterial hypertension, 8.1% presented in New York Heart Association functional class IV, 9.3% had a need for intensive care unit admission, and one experienced maternal mortality. Adverse fetal outcomes, including operative vaginal delivery, mean duration of hospital stay, fetal growth restriction, preterm birth (<37 weeks), low birth weight (<2,500 g), 5-minute APGAR score <7, and neonatal intensive care unit admissions, were significantly higher in women with CHD than in women without heart disease. Conclusion Women with CHD have a higher risk of adverse fetal and cardiac outcomes. The outcome can be improved with proper pre-conceptional optimization of the cardiac condition, good antenatal care, and multidisciplinary team management.

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