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      • 冷間加工의 磨耗에 對한 影響

        李任烈 단국대학교 1986 論文集 Vol.20 No.-

        The wear experiment was conducted on couples consisting of iron, nickel, Fe-36% Ni and 3% silicon steel pins sliding against a tool steel disc. It has been found that the wear rate in air at room temperature lis independent to me hardness. The experimental observations are well related to the oxidation characteristics. However, the rate of oxidative wear is much higher than that for static oxidation due to the difference in the activation energy for oxidative wear. The lower energy for oxidational wear indicates that the rubbing surfaces are mechanically activated and high diffusivity path for diffusion of matrix elements and oxygen are produced during the sliding motion. The higher wear rate for cold-worked samples than for the annealed ones are associated with the higher oxidation rate for the cold-worked specimen.

      • 산소와 구리의 공정반응에 의한 구리와 알루미나의 직접접합

        이임렬,유환성 단국대학교 신소재기술연구소 1991 신소재 Vol.1 No.-

        본 연구에서는 구리표면의 구리-산소간의 공정반응에 의하여 형성된 Cu-Cu_2O 공용액상 피막으로 고체 Cu금속과 Al_2O_3세라믹을 압력없이 직접접합시키는 방법을 조사하였으며 접합조건에 따른 접합특성, 파면 및 계면분석을 SEM, EDS, XRD 및 peeling 시험을 통하여 분석하였다. 1.5×10^-1 torr 진공하에서 1015℃의 온도에서 산화시킨 구리시편은 미세한 산화물 Cu_2O가 표면에 잘 형성되었다. 그후 공정온도 1065℃ 이상의 접합온도 1075℃에서 5분간 10^-3 torr의 진공하에서 직접접합시킨 시편은 접합력이 우수한 Cu/Al_2O_3 접합이 되었으며 접합후 구리기니 내에는 Cu2O가 석출된 공융조직을 갖고 있었다. 3분 산화조건에서 충분한 액상이 형성되어 29kg의 최대 접합강도를 보였으며 산회시간이 이보다 짧거나 불충분한 액상의 형성이나 산화물내의 균열 등으로 결합력이 저하하였다. 파단후 Al_2O_3 표면에는 Cu_2O nodule이 존재하였고 Cu족에는 nodule이 빠진홈을 관찰할 수 있었는바 cu2O/Al_2O_3계면 접착력은 Cu.Cu_2O계면보다 강함을 알 수 있었다. 또한 파단면에는 반응 생성물 CuAlO_2가 접합중 형성되었으나 이 반응층 두께는 SEM분해능 이하인 매우 얇은 것으로 생각된다. The direct bonding between Cu and Al_2O_3, utilizing Cu-Cu_2O skin melt formed on Cu surface by eutectic reation of Cu-O, is investigated in this study. The bond strength, fracture surface and interface structure with bonding conditions have been studied using SEM, EDS, XRD and peeling test. A fine Cu_2O is formed on the surface of Cu with oxidation at 1015℃ under 1.5×10^-1torr vacuum. After oxidation, the bonded specimen conducted at 1075℃ in 10^-3torr vacuum for 5minutes, higher temperature than its eutectic temperature of 1065℃, has a good strength having a Cu_2O precipitated structure in Cu matrix upon cooling. It has been found that the maximum bonding force of 29kg is obtatined for 3 minutes of oxidation. However, the adhesion forces are decreased with shorter or longer oxidation than this due to the formation of insufficient liquid skin or crack within oxide. After peeling test, Al_2O_3 surface is covered with Cu_2O nodules which are pulled out of Cu surface indication that Cu_2O/Al_2O_3 adhesion force is stronger than that of Cu/Cu_2O. Moreover a reaction phase of CuAlO_2, thought to be very thin layer below the resolution of SEM, is also formed during the bonding process.

      • SCIESCOPUSKCI등재
      • Plasma protein profiles in early asthmatic responses to inhalation allergen challenge

        Rhim, T.,Choi, Y.-S.,Nam, B.-Y.,Uh, S. T.,Park, J. S.,Kim, Y.-H.,Paik, Y.-K.,Park, C.-S. Wiley (Blackwell Publishing) 2009 Allergy Vol.64 No.1

        <P>Although mediators, such as lipids, cytokines, and chemokines, are related to the appearance of an IPR, there has been no reliable indicator to predict conditions for the appearance of an IPR. In this study, we adopted a proteomic approach to investigate the pathogenesis at the level of the plasma proteins and to develop plasma markers to predict the appearance of an IPR following an inhalation challenge with Dermatophagoides pteronyssinus (D.p.). Sixteen mild asthmatics were recruited. Plasma was obtained before challenge and when a decline in forced expiratory volume in 1 s (FEV(1)) values greater than 20% from the phosphate-buffered saline value was achieved during D.p. allergen challenge (positive responders), or at 60 min after the highest concentration of D.p. allergen was inhaled (negative responders). After comparing normalized volumes of the spots in the two groups, differentially expressed spots were identified using intra-gel digestion and mass spectrometric analysis. Before D.p. antigen challenge, four spots of gamma fibrinogen and its isoforms were significantly decreased and two spots of complement C3 fragments were significantly increased in the positive responders compared to the negative responders. After D.p. antigen challenge, complement C3 fragment was persistently higher, while gamma fibrinogen was lower in the positive responders than in the negative responders. A validation study using Western blotting showed that gamma fibrinogen expression in the IPR-positive asthmatics was significantly decreased compared to the average of the IPR-negative asthmatic control group. These results indicate that alterations in the complement cascade and fibrinogen may predispose patients to the appearance of an immediate response to D.p. allergen challenge and may provide plasma markers to predict the appearance of an IPR.</P>

      • Imaging of Steel Bars Embedded inside Mortar Specimens for Nondestructive Testing

        Rhim, Hong-Chul,Park, Kyung-Hyun Korea Concrete Institute 2000 KCI concrete journal Vol.12 No.1

        Ground Penetrating Radar (GPR) with 1 GHz antenna has been used to locate a steel bar embedded inside laboratory-prepared mortar specimens. Four mortar specimens are made with the dimensions of 100 cm (length) x 100 cm (width) x 14 cm (depth). One specimen had no bars and the other three specimens had a Dl9 steel bar at 4, 6. and 8 cm depth. As a part of the experimental work, the dielectric constants of mortar specimens are measured during curing. As the curing time increased. the dielectric constant decreased with decreasing moisture content inside the specimen. The steel bar embedded inside mortar specimens has been successfully identified in all three cases. The results using signal processing scheme developed in this study significantly improved the output of a commercially available radar system.

      • SCIEKCI등재

        살충성 형질 전환 토마토 식물체의 분자 육종

        Rhim, Seong Lyul 한국농화학회 1998 Applied Biological Chemistry (Appl Biol Chem) Vol.41 No.2

        The transgenic tomato plants showing the insecticidal activity against the coleopteran insect larvae have been bred to the 4th generation (R₄). The Bacillus thuringiensis subsp. tenebrionis (B.t.t.)-toxin gene and the expression were detected in the R₄ transgenic plants. The expression of the toxin gene conferred a coleopteran insect larvae tolerance to the transgenic tomato plants. The ploidy levels of the R₄ transgenic plants were diploid. The results indicated that the toxin gene was inherrited to the next generation and expressed. Such a molecular breeding can provide a method for a permanent control of insects a agronomic relevance.

      • Antiviral activity against Influenza A (H1N1) virus of Oak mushroom (Lentinula edodes) Extract

        Rhim Ryoo,Hyorim Lee,Mi-Jeong Park,Eunjin Kim,Ki Won Lee 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

        Oak mushroom (Lentinula edodes) have been recognized for helping to improve immunity in various oriental medicine libraries. However, this mushroom is vaguely known only as a healthy forest product without being clear on which pathogens this is effective against. Accordingly, in this study, we tried to evaluate the antiviral activity against viruses that cause human infection by using aqueous extract of oak mushroom. The material used in this study was the cultivar "Sanbaekhyang" developed and cultivated by the National Institute of Forest Science. For the antiviral activity test, the hot water extract of the mushroom was prepared by incubating 50g of the dried fruiting body powder in 500 ml of distilled water at 100°C for 2 hours. Antiviral efficacy evaluation was performed with the novel swine- origin influenza A (H1N1) virus by modified ASTM E1052- 11 method using plaque assay. As a result of measuring the decrement in the virus for 2 hours, this exctract showed 99.997% antiviral efficacy against the virus. This result indicated that the oak mushroom extract is highly valuable for use as a personalized food and pharmaceutical material for the prevention of respiratory pathogens.

      • Expression, Purification, and Characterization of Prothrombin Kringle 2

        Rhim, Tai-Youn,Kim, Eun-kyung,Park, Chan-Soo,Kim, Soung-Soo Korean Society for Biochemistry and Molecular Biol 1999 Journal of biochemistry and molecular biology Vol.32 No.2

        Previously, we reported that the prothrombin kringle 2 (fragment 2), induced by LPS administration into rabbit, inhibited bFGF-stimulated BCE cell growth (Lee et al., 1998). In this study, we cloned and overexpressed the kringle 2 domain of rabbit and human prothrombin as a fusion protein with the pelB leader sequence in E. coli using the T7 promoter. The fusion protein was cleaved during translocation into the peri plasmic space, and cleaved recombinant protein was readily isolated from whole cell lysate by DEAE-Sepharose and Sephacryl S-200 gel filtration chromatography. Both the recombinant rabbit and human prothrombin kringle 2 showed very similar biochemical and functional characteristics to the rabbit prothrombin kringle 2 purified from rabbit serum, in terms of abnormal electrophoretic migration and endothelial cell growth inhibitory activity.

      • KCI등재
      • KCI등재SCISCIE

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