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Allozyme Variation in Ten Indian Natural Populations of Drosophila Immigrans
Parkash, Ravi,Yadav, J P 한국유전학회 1991 Genes & Genomics Vol.13 No.4
Ten Indian natural populations of D. immigrans, collected along 12˚ longitudinal and 6˚latitudinal ranges, were analysed electrophoretically for allozymic variation of eight gene-enzyme systems. Adh, α-Gpdh, Sod and three Est loci were found to be monomorphic, Mdh locus revealed some geographical variation while overall patterns of genie variation at six other polymorphic loci depicted similarities. Nei's significantly higher values of genetic similarities between populations pairs and low values of Wright's fixation index (F_(ST)) revealed that Indian populations of D. immigrans are genetically homogeneous for the loci analysed. Such observations are consistent with narrow nich-width in terms of food resources and climatic adaptation of this species. However, statistical analysis of allopatric populations of D. immigrans suggest genic differentiation at most polymorphic loci. The available data on genetic structure of D. immigrans populations could be explained on the basis of migration as well as balancing natural selection mechanisms.
Latitudinal Variation at adh and est loci in Indian Populations of Two Colonizing Drosophilids
Parkash, Ravi,Yadav, J P,Shamina 한국유전학회 1992 Genes & Genomics Vol.14 No.1
Population samples of Drosophila melanogaster and Zaprionus indianus, collected along 20˚ latitudinal range of the Indian subcontinent, were analysed electrophoretically as well as with heat denaturation technique for patterns of allozymic variation at Adh and Est loci. The Adh^F and Est-6^S allelic frequencies in D. melanogaster; and Adh^F and Est-1^F allelic frequencies in Z, indianus were found to be positively and significantly correlated with increasing latitude. The consistency of the direction of geographical clinal variation across different drosophilids and among continental populations of D. melanogaster; and the occurrence of genie divergence at these loci provide evidence for balancing natural selection mechanisms to maintain such latitudinal allozymic variation in two different colonising species.
Allozymic Homogeneity in Indian Populations of Drosophila Busckii
Parkash, Ravi,Yadav, J P,Shamina 한국유전학회 1992 Genes & Genomics Vol.14 No.2
Allozyme polymorphism for nine gene-enzyme systems were studied through horizontal starch gel electrophoresis in isofemale lines derived from six Indian populations of D. busckii. Five autosomal loci coded for dimeric Aph, Odh, Mdh, Me and Ao phenotypes, and allelic variants were represented by segregating single-band variants. complex Acph patterns were controlled by a duplicate locus while polymorphic esterase loci coded for monomeric enzymes. However, Adh and α-Gpdh were controlled by a single locus each and homozygous strain depicted epigenetic two-banded phenotypes. The Indian geographical populations of D. busckii revealed allozymic similarity at all the loci examined. However, the extent of genic diversity was found to be significantly higher than those of U.S. populations. The available data on the patterns of genetic structure of Indian as well as U.S.populations of D. busckii concurred with that of D. simulans in respect of allozymic homogeneity, lack of geographical clinal variation and lack of adaptive flexibility to a range of climatic conditions. Thus, the allozymic uniformity observed in D. busckill might constitute a genetic strategy for this colonising species in respect of its limited niche-width for spatial climatic adaptations.
Allozymic Polymorphism in Indian Colonising Natural Populations of Zaprionus Indianus
Parkash, Ravi,Yadav, J P 한국유전학회 1992 Genes & Genomics Vol.14 No.4
Twelve Indian natural populations of Z. indianus. collected along 22˚latitudinal range, were analysed electrophoretically for allozymic variation of seven gene-enzyme systems. Interestingly all the seven Est loci were found to be highly polymorphic in all the populations of Z. indianus. Except Mdh-2 all the fourteen loci revealed extensive polymorphism. The Indian continental populations of Z. indianus revealed higher genetic similarities on the basis of Nei's genetic indices. The genetic structure of Z. indianus populations were characterised by significantly higher values of genetic indices as compared with other sympatric colonising Drosophila species from India; extensive inter-populational genotypic as well as allelic frequency heterogeneity; and higher genic differentiation at all the loci. All the polymorphic loci in geographical populations of Z. indianus revealed latitudinal clines and changes in allelic frequencies were found to correlate with latitude. The patterns of genie differentiation in Z. indianus population were comparable to those of D. melanogaster populations from India and other continents. The occurrence of higher genetic variability in Z. indianus populations were in agreement with its habitat generalist or broad niche-width characteristics i. e. the species populations utilised diverse food resources and displayed adaptation to variable climatic conditions. Thus, the observed genic divergence patterns in colonising populations of Z. indianus could be maintained by balancing natural selection varying spatially along the north-south axis of the Indian sub-continent.
Load Balancing Strategy using Round Robin Algorithm
Dong Hyun Youm,Ravi Yadav 사단법인 미래융합기술연구학회 2016 아시아태평양융합연구교류논문지 Vol.2 No.3
Current cloud computing environment serves in practically every field of our life. Be that as it may, while satisfying parts and loads of client solicitations it confronts couple of confinements to be overcome. Alongside giving us offices like virtualization, asset sharing, universality, utility registering it request that we concentrate on issues like security, authentication, and adaptation to internal failure, load balancing, and availability. Part of work is being completed to accomplish stack adjusting in cloud framework now days. There are such a large number of load adjusting calculations playing out their errand on various layers of cloud with various levels of complexities. To accomplish incredible level of load adjusting individuals utilize numerous mind boggling calculations. Be that as it may, thus it includes all the more handling burden the framework executing such logic.
Phonatory Characteristics of Male Patients with Classic Essential Tremor
Preetie Shetty Akkunje,Belur Keshavaprasad Yamini,Ravi Yadav,Nagarajarao Shivashankar,Palash Kumar Malo,Kandavel Thennarasu,Shantala Hegde,Pramod Kumar Pal 대한파킨슨병및이상운동질환학회 2021 Journal Of Movement Disorders Vol.14 No.3
This retrospective case-control study compared classic ET patients with age and sex-matched controls. The ET population was subgrouped based on auditory perceptual voice analysis. Electroglottography and acoustic voice samples obtained from both groups were analyzed for contact quotient (CQ) and multidimensional voice program parameters, i.e., fundamental frequency (F0), perturbation, noise, and tremor parameters.
Clinical and Imaging Profile of Patients with Joubert Syndrome
Bharath Kumar Surisetti,Vikram Venkappayya Holla,Shweta Prasad,Koti Neeraja,Nitish Kamble,Ravi Yadav,Pramod Kumar Pal 대한파킨슨병및이상운동질환학회 2021 Journal Of Movement Disorders Vol.14 No.3
Nine patients were included in the study. All patients had facial dysmorphism and ocular abnormalities, and 4 patients had dystonia. Ocular tilt reaction and alternate skew deviation (66%) were the most common ocular abnormalities. Horizontally aligned superior cerebellar peduncles were observed in all four patients with diffusion tensor imaging, with a lack of decussation in three. Exome sequencing performed in four patients revealed novel variants in the MKS1, CPLANE1, and PIBF1 genes.
Shweta Prasad,Amitabh Bhattacharya,Lulup Kumar Sahoo,Dhruv Batra,Nitish Kamble,Ravi Yadav,Dwarakanath Srinivas,Pramod Kumar Pal 대한파킨슨병및이상운동질환학회 2021 Journal Of Movement Disorders Vol.14 No.1
There are very significant knowledge gaps and misconceptions regarding DBS among patients with PD and caregivers. Adequate and appropriate education is necessary to clarify these misconceptions to avoid the development of unrealistic expectations and poor satisfaction.
The Non-Motor Symptom Profile of Progressive Supranuclear Palsy
Sudhakar Pushpa Chaithra,Shweta Prasad,Vikram Venkappayya Holla,Albert Stezin,Nitish Kamble,Ravi Yadav,Pramod Kumar Pal 대한파킨슨병및이상운동질환학회 2020 Journal Of Movement Disorders Vol.13 No.2
ObjectiveaaNon-motor symptoms (NMSs) significantly contribute to increased morbidity and poor quality of life in patients withparkinsonian disorders. This study aims to explore the profile of NMSs in patients with progressive supranuclear palsy (PSP) usingthe validated Non-Motor Symptom Scale (NMSS). MethodsaaSeventy-six patients with PSP were evaluated in this study. Motor symptoms and NMSs were evaluated using the PSPRating Scale (PSPRS), Unified Parkinson’s Disease Rating Scale-III, Montreal Cognitive Assessment, Hamilton Depression (HAMD)and Anxiety Rating Scales, Parkinson’s Disease Sleep Scale (PDSS) and NMSS. NMS severity and prevalence were also comparedbetween patients with PSP-Richardson syndrome (PSP-RS) and those with PSP-parkinsonism. ResultsaaAll subjects in this cohort reported at least 2 NMSs. The most prevalent NMSs in patients with PSP were in the domainsof sleep/fatigue, mood/cognition, and sexual function. The least prevalent NMSs were in the domains of cardiovascular includingfalls, and perceptual problems/hallucinations. Significant correlations were observed between the NMSS scores and HAM-D,PDSS, PSPRS scores and PSPRS sub-scores. The severity of NMSs was unrelated to the duration of illness. Patients with PSP-RSreported a higher severity of drooling, altered smell/taste, depression and altered interest in sex and a higher prevalence of sexualdysfunction. ConclusionaaNMSs are commonly observed in patients with PSP, and the domains of sleep, mood and sexual function aremost commonly affected. These symptoms contribute significantly to disease morbidity, and clinicians should pay adequate attentionto identifying and addressing these symptoms.