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The mediterranean diet’s effect on stroke risk
Zain Qureshi(Zain Qureshi ),Dolores Becker(Dolores Becker ),Umar Farooq(Umar Farooq ) 한국축산식품학회 2022 Food and Life Vol.2022 No.2
The Mediterranean diet has been growing in popularity as preventive medicine has made way in the healthcare community. Doctors are telling patients to adopt this diet due to its role in lowering stroke rates and other cardiovascular diseases in both Italy and Greece. These two countries have some of the lowest stroke numbers in the world, and experts believe this is the result of the diet and lifestyle of the people of that region. The diet includes foods such as fruits, vegetables, nuts, fish, and olive oil, along with less cholesterol, saturated fats, and trans fats. These specific foods and combinations of foods include properties that can prevent high blood pressure. We will explore the capabilities of the Mediterranean diet in preventing stroke, and the importance of preventive medicine in healthcare.
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A Meta-analysis: Shape of Age Effects and Second Language Grammar Acquisition
Muhammad Asif Qureshi 아시아영어교육학회 2021 The Journal of Asia TEFL Vol.18 No.2
This study reports findings of a meta-analysis on the effects of the age of first exposure, known as the age of onset (AO), on the acquisition of morphosyntax in a second language (L2). Several studies report restrictive effects of AO on L2 grammar acquisition (Abrahamsson, 2012; DeKeyser et al., 2010; Qureshi, 2016); however, there is a disagreement about the way sensitivity to second language acquisition declines (Birdsong, 2009; Long, 2013). Researchers disagree about the nature of the decline and argue whether the decrease that occurs in learners’ ultimate proficiency in the second language is gradual and continuous or gradual but followed by a plateau, without further decline. To explore the nature of AO, 29 samples from 14 studies were analyzed. The results revealed a large effect size1 (d = 1.13, SD = .06) for the impact of AO on ultimate proficiency in L2 morphosyntax. However, for the disaggregated data (i.e., when earlier & late learners are separated), a linear decline was observed for the 6 to 16 age-group (21 samples), while a flattening of the regression line was detected for the 17 to 24 age-group (8 samples). More importantly, the findings revealed two different shapes of decline based on participants’ first language and the target L2. Overall, the findings support a bounded critical period for second language acquisition and indicate the typological distance between the two languages as a major influencing factor.
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Qureshi, M.S.,Habib, G.,Samad, H.A.,Lodhi, L.A.,Usmani, R.H. Asian Australasian Association of Animal Productio 1999 Animal Bioscience Vol.12 No.7
Fifth one Nili-Ravi dairy buffaloes in their last two months of gestation, were selected in NWFP Pakistan. Rectal palpation was carried out fortnightly, until the occurrence of first estrus. Ovulation was confirmed per rectum and milk progesterone levels (MPL). Body condition score (BCS)was recorded weekly. Milk samples were collected weekly for MPL and blood samples fortnightly for metabolites analysis. Milk yield was recorded and samples were collected for milk fat. The buffaloes calving during the normal breeding season (NBS, August to January)had short (p<0.01) postpartum estrus interval of $55.95{\pm}4.90$ days versus $91.15{\pm}11.61 $ days in the buffaloes calving during the low breeding season (LBS, February to July). MPL in the LBS calvers remained lower than NBS calves (p<0.01). The incidence of silent ovulation was higher during LBS as compared to NBS (70.6% versus 29.4%). MPL showed a pattern opposite to atmospheric temperature. In NBS calvers serum glucose levels were higher (p<0.01) and magnesium levels were lower (p<0.01) than LBS calvers. Higher serum urea was found in summer and spring than that autumn and winter (p<0.05). The reproductive performance in buffaloes calving in the LBS coincided with a low BCS (p<0.01). Fat corrected milk production (FCM) was higher in NBS than LBS (p<0.01) calvers.
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Qureshi, Z.,Mahjabeen, I.,Baig, R.M.,Kayani, M.A. Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23
Genetic polymorphisms in homologous recombination repair genes cause an abnormal development of cancerous cells. In the present study we evaluated the possibility of breast cancer association with single nucleotide polymorphisms of RAD51, XRCC2 and XRCC3 genes. Polymorphisms selected in this study were RAD51 135G/C, XRCC2 Arg188His; and XRCC3 Thr241Met. Each polymorphism was genotyped using Polymerase chain reaction-restriction fragment length polymorphism in study cohort of 306 females (156 breast cancer patients and 150 controls). We observed that heterozygous variant genotype (GC) of RAD51 135 G/C polymorphism was associated with a significantly (OR=2.70; 95%CI (0.63-1.79); p<0.03) increased risk of breast cancer. In case of the XRCC3 gene we observed that frequency of heterozygous (OR=2.88; 95%CI (1.02-8.14); p<0.02) and homozygous (OR=1.46; 95%CI (0.89-2.40); p<0.04) genotype of Thr241Met polymorphism were significantly higher in breast cancer patients. For the Arg188His polymorphism of XRCC2, ~2fold increase in breast cancer risk (OR=1.6, 95%CI = 0.73-3.50) was associated with GA genotype with a p value for trend of 0.03. Our results suggest that the 135G/C polymorphism of the RAD51, Thr241Met polymorphism of XRCC3 and Arg188His polymorphism of XRCC2 can be independent markers of breast cancer risk in Pakistan.
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TRAIL and Bortezomib: Killing Cancer with Two Stones
Qureshi, Muhammad Zahid,Romero, Mirna Azalea,Attar, Rukset,Javed, Zeeshan,Farooqi, Ammad Ahmad Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.4
Cancer genomics and proteomics have undergone considerable broadening in the past decades and increasingly it is being realized that solid/liquid phase microarrays and high-throughput resequencing have provided platforms to improve our existing knowledge of determinants of cancer development, progression and survival. Loss of apoptosis is a widely and deeply studied process and different approaches are being used to restore apoptosis in resistant cancer phenotype. Modulating the balance between pro-apoptotic and anti-apoptotic proteins is essential to induce apoptosis. It is becoming more understood that pharmacological inhibition of the proteasome might prove to be an effective option in improving TRAIL induced apoptosis in cancer cells. Keeping in view rapidly accumulating evidence of carcinogenesis, metastasis, resistance against wide ranging therapeutics and loss of apoptosis, better knowledge regarding tumor suppressors, oncogenes, pro-apoptotic and anti-apotptic proteins will be helpful in translating the findings from benchtop to bedside.
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Qureshi, M. Zahid Iqbal,Chan, A.L.S. Techno-Press 2016 Wind and Structures, An International Journal (WAS Vol.22 No.4
The mechanical and aerodynamic effect of building shape plays a dominate role in the pedestrian level wind environment. These effects have been presented in numerous studies and are available in many wind codes. However, most studies have focused on wind flow around conventional buildings and are limited to few wind directions. The present study investigated wind circulation in the re-entrant corners of cross-shaped high-rise buildings from various wind directions. The investigation focused on the pedestrian level wind environment in the re-entrant corners with different aspect ratios of building arrangements. Ninety cases of case study arrangements were evaluated using wind tunnel experimentation. The results show that for adequate wind circulation in the re-entrant corners, building orientations and separations play a critical role. Furthermore, in normal wind incident directions and at a high aspect ratio, poor wind flow was observed in the re-entrant corners. Moreover, it was noted that an optimized building orientation and aspect ratio significantly improved the wind flow in re-entrant corners and through passages. In addition, it was observed that oblique wind incident direction increased wind circulation in the re-entrant corners and through passages.
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Study on Factors Leading to Seasonality of Reproduction in Dairy Buffaloes. I. Nutritional Factors
Qureshi, M.S.,Samad, H.A.,Habib, G.,Usmani, R.H.,Siddiqui, M.M. Asian Australasian Association of Animal Productio 1999 Animal Bioscience Vol.12 No.7
Fifth one Nili-Ravi dairy buffaloes were studied in North-west Frontier Province of Pakistan. Rectal examination of reproductive organs was carried out on days 14 and 21 and then fortnightly. Milk samples were collected and analyzed for progesterone levels (MPL). Feed samples were collected fortnightly and analyzed. The buffaloes calving during the normal breeding season (NBS, August to January) (p<0.01) postpartum estrus interval of 55.95 days versus 91.15 days in those calving during the low breeding season (LBS, February to July). MPL in the LBS remained lower than the NBS (p<0.01). Shortest postpartum ovulation interval was noted during autumn(August to October), followed by winter (November to January), summer (May to July) and spring (February to April). The incidence of silent ovulations was during LBS than NBS (70.6% versus 29.4%). In autumn there was minimum intake of crude protein (CPI) and maximum intake of metabolizable energy (MEI, p<0.01). Calcium intake was higher in NBS than LBS calving buffaloes (p<0.01). Phosphorus, copper and magnesium intake was lower (p<0.05) and zinc intake was higher (p<0.01) in autumn, It was (p<0.05) and zinc intake was higher (p<0.01) in autumn, It was concluded that onset of breeding season was associated with increasing MEI and decreasing CPI and minerals intake.
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Qureshi, N. M.,Shinde, M. D.,Baeg, J. O.,Kale, B. B. Royal Society of Chemistry 2017 New journal of chemistry Vol.41 No.10
<P>Developing stable semiconducting oxides that are active in the visible region for photocatalytic reactions is a major technological challenge. Herein, we report a facile co-precipitation based synthesis of PbCrO4 nanostructures with the aim to study their hitherto unreported hydrogen production potential. It has been observed that monoclinic PbCrO4 nanorods have been generated using a simple co-precipitation method in the presence of water and methanol as solvents while spherical nanostructures are produced using an ultrasonication assisted co-precipitation method. The nanorods synthesized by the aqueous co-precipitation method have yielded the highest rate of hydrogen production (3214 mu mol h(-1) 0.5 g(-1)) by splitting hydrogen sulfide (H2S) gas.</P>
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Variation in Milk Fatty Acid Composition with Body Condition in Dairy Buffaloes (Bubalus bubalis)
Qureshi, Muhammad Subhan,Mushtaq, Anila,Khan, Sarzamin,Habib, Ghulam,Swati, Zahoor Ahmad Asian Australasian Association of Animal Productio 2010 Animal Bioscience Vol.23 No.3
Buffaloes usually maintain higher body condition and do not produce milk at the cost of their own body reserves under tropical conditions. The mobilization of body reserves for fulfilling the demands of lactation has been extensively studied in dairy cows while limited work is available on this aspect in dairy buffaloes. Therefore, the present study was conducted to examine variations in milk fatty acid profiles with body condition in Nili-Ravi buffaloes. A total of 24 Nili-Ravi buffaloes within 60 days after parturition, were selected from a private dairy farm in the district of Peshawar. All animals consumed the same diet during the experimental period. A total of 576 raw milk samples were collected for laboratory analysis. The study continued up to 6 months during 2008. Body condition score (BCS), milk yield and composition were recorded once a week. Means for milk fatty acid profile were compared for various levels of BCS. The mean milk yield and fat content were 9.28 kg/d and 5.36%, respectively. The total saturated fatty acids (SFA) were 64.22 g/100 g and the unsaturated fatty acids (UFA) were 35.79 g/100 g. Of the SFA the highest amount was recorded for $C_{16:0}$, followed by $C_{18:0}$, and $C_{14:0}$. The total sum of hypercholesterolemic fatty acids (HCFA, $C_{12:0}$, $C_{14:0}$ and $C_{16:0}$) was 43.33 g/100 g. The concentrations of UFA were greater for moderate BCS followed by poor and highest BCS while SFA showed the opposite trend. The correlation analysis showed that milk yield was negatively affected by BCS and milk fat positively affected, though non-significantly. The present study suggests that Nili-Ravi dairy buffaloes produce similar milk to dairy cows regarding availability of cardioprotective fatty acids, with the highest concentration of $C_{18:1\;cis-9}$. Two HCFA ($C_{12:0}$ and $C_{14:0}$) were associated with higher body condition. Buffaloes with moderate body condition yielded milk containing healthier fatty acids.
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