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Paulo S. André,Ant?io L. Teixeira,Armando N. Pinto,Lara P. Pellegrino,Berta B. Neto,J?e F Rocha,Jo? L. Pinto,Paulo N. Monteiro 한국전자통신연구원 2006 ETRI Journal Vol.28 No.2
In this letter, we will evaluate the performance degradation of a 40 km high-speed (40 Gb/s) optical system, induced by optical fiber variations of the chromatic dispersion induced by temperature changes. The chromatic dispersion temperature sensitivity will be estimated based on the signal quality parameters.
Paulo Gustavo Kotze,Daniela Oliveira Magro,Barbara Saab,Mansur Paulo Saab,Lilian Vital Pinheiro,Marcia Olandoski,Maria de Lourdes Setsuko Ayrizono,Carlos Augusto Real Martinez,Claudio Saddy Rodrigues 대한장연구학회 2018 Intestinal Research Vol.16 No.1
Background/Aims: The use of anti-tumor necrosis factor (anti-TNF) agents seems to reduce surgical rates and delay surgicalprocedures in prospective trials and population-based studies in the management of Crohn’s disease (CD). This study aimedto identify whether preoperative anti-TNF agents influence the time from diagnosis to surgery. Methods: An observationalretrospective cohort study was conducted on patients with CD submitted to intestinal resections due to complications ormedical therapy failure in a period of 7 years. The patients were allocated into 2 groups according to their previous exposure toanti-TNF agents in the preoperative period. Epidemiological aspects regarding age at diagnosis, smoking, perianal disease, andpreoperative conventional therapy were considered. A Kaplan-Meier survival analysis was used to outline possible differencesbetween the groups regarding the time to surgery. Results: A total of 123 patients were included (71 and 52 with and withoutprevious exposure to biologics, respectively). The overall time to surgery was 108±6.9 months (maximum, 276 months). The survival estimation revealed no difference in the mean time to intestinal resection between the groups (99.78±10.62 months inthe patients without and 114.01±9.07 months in those with previous anti-TNF use) (log-rank P =0.35). There was no significantdifference in the time to surgery regarding perianal CD (P =0.49), smoking (P =0.63), preoperative azathioprine (P =0.073) andsteroid use (P =0.58). Conclusions: The time from diagnosis to surgery was not influenced by the preoperative use of anti-TNFtherapy in this cohort of patients.
A Heart Rate Variability-based Smart Approach to Analyze Frailty in Older Adults
Joao Paulo do Vale Madeiro,Paulo Cesar Cortez,Arnaldo Aires Peixoto Junior,Joao Alexandre Lobo Marques,Antonio Alisson Pessoa Guimara,John Hebert da Silva Felix 한국산학기술학회 2015 SmartCR Vol.5 No.4
This paper presents an algorithm that applies metrics derived from automatic QRS detection and segmentation in electrocardiogram signals for analyzing Heart Rate Variability to study the evolution of metrics in the frequency domain of a clinical procedure. The analysis was performed on three sets of elderly people, who are categorized according to frailty phenotype. The first set was comprised of frail elderly, the second pre-frail elderly, and the third robust elderly. Investigators from many disciplines have been encouraged to contribute to the understanding of molecular and physiological changes in multiple systems that may increase the vulnerability of frail elderly. In this work, the frailty phenotype can be characterized by unintentional weight loss, as self-reported, fatigue assessed by self-report, grip strength (measured directly), physical activity level assessed by self-report and gait speed (measured). The results obtained demonstrate the existence of significant differences between Heart Rate Variability metrics for the three groups, especially considering a higher preponderance for sympathetic nervous system for the group of robust patients in response to postural maneuver.
Topology optimization of bracing systems in buildings considering the effects of the wind
Paulo U. Silva,Rayanne E.L. Pereira,Gustavo Bono 국제구조공학회 2023 Structural Engineering and Mechanics, An Int'l Jou Vol.86 No.4
Nowadays, urban centers are increasingly vertical, making architects and engineers look for more efficient tools to analyze the effects of wind on tall buildings. Topology optimization can be used as an efficient tool for the design of bracing systems. Therefore, this work obtained the wind loads that act in the CAARC building, following the Brazilian standard NBR 6123/1988 and using Computational Fluid Dynamics. Four loading situations were considered, using the SIMP and BESO methods to optimize two-dimensional structures. A comparison between the SIMP and BESO methods is presented, showing the differences in the geometry of the solution found by both methods, the percentage variation in the objective function values and the dimensionless processing time. The solutions obtained through the loads obtained by the Brazilian standard are also compared with the numerical solutions obtained by CFD. The results show that the BESO method presented more rigid structures compared to the SIMP method. The bracing structures obtained with the SIMP method always present similar patterns in the distribution and quantity of bars, in contrast to the BESO method where no characteristic topology pattern was observed. It was concluded that even though the structures obtained by the BESO method presented greater stiffness, the SIMP method was less susceptible to the methodology used for the determination of wind loads. Additionally, it was evident the great potential that the combination topology optimization and computational wind engineering have in the design of bracing systems of high functional and aesthetic standards.
Experimental and numerical study of headed bars embedded in RC members under tension
Paulo F.M. Santana,Patricia C.S. Silva,Mauricio P. Ferreira,Luciano M. Bezerra,Marcos H. Oliveira 국제구조공학회 2022 Structural Engineering and Mechanics, An Int'l Jou Vol.84 No.4
Headed bars are often used when there is insufficient space for a straight or curved bar to be fully developed to ensure the transference of forces between steel and concrete in several types of connections between structural members. In such cases, the concrete breakout strength of the headed bars can be a critical point of the design and must be considered appropriately. This paper evaluates the tensile strength of headed bars embedded in reinforced concrete members, failing due to concrete breakout. Four experimental tests on headed bars embedded in slender concrete members are presented and discussed, showing that strength previsions from the design codes can be significantly conservative as they ignore the contribution from the flexural reinforcement. 3D finite element models were developed using Abaqus Unified FEA to simulate the tested specimens, and it was observed that they were able to reproduce the formation of the concrete cone accurately, besides the response and resistance observed in tests. Furthermore, the experimental, numerical, and design code resistances are compared and discussed. A new equation to evaluate the concrete cone strength of the tested headed bars is proposed, which takes into account parameters not explicitly considered in the current design equations.
Paulo A. Augusto,Teresa Castelo-Grande,Pedro Augusto,A.M. Est?vez,Domingos Barbosa 한국물리학회 2007 Current Applied Physics Vol.7 No.3
The theoretical principles of MAGCLATMsusceptibility, are presented for the magnetic particles. An empirical coecient (TCG2) is introduced in the equations of movement toaccount for deviations between experimental and theoretical values.
Paulo A. Augusto,Teresa Castelo-Grande,Pedro Augusto,Domingos Barbosa,A.M. Est?vez 한국물리학회 2007 Current Applied Physics Vol.7 No.3
A new device, MAGCLATMoped by the authors. In a previous article the equations of movement for non-magnetic particles in this new device were analyzed and inthis paper the limiting conditions set by the dierent variables and equations of movement are presented for the case of the non-magneticparticles. The knowledge of these limiting conditions is important as they set the boundaries within which we may manipulate theMAGCLATM’s operating and design variables.
Paulo Schiavom Duarte,Luciana Audi de Castroneves,Heitor Naoki Sado,Marcelo Tatit Sapienza,Ana Amélia Fialho de Oliveira Hoff,Carlos Alberto Buchpiguel 대한핵의학회 2018 핵의학 분자영상 Vol.52 No.4
Herein, we report a case of a 19-year-old man with multiple endocrine neoplasia type 2B (MEN2B) and medullary thyroidcarcinoma (MTC) diagnosed when he was 12 years of age. The patient had previously undergone total thyroidectomy, cervicalradiotherapy, and chemotherapy. He progressed with known bone, pulmonary, and lymph node metastases and was scanned with18F-fluoride (18F-NaF) and 68Ga-dotatate whole-body positron emission tomography/computed tomography (PET/CT) for metastaticdisease monitoring.We found that the MTC bone metastases and soft tissue calcified metastases were better characterizedon 18F-NaF PET/CT than on 68Ga-dotatate PET/CT. This case illustrates that the 18F-NaF PET/CT could be helpful not only tothe detection of bone metastases but also to the detection of calcified soft tissue metastases in patients with MTC.
Intramammary sentinel lymph node with capsular extravasation in breast cancer
Paulo Roberto De Alcantara Fil,Carla Curi,Camila Souza Guatelli,Cynthia Aparecida B. de Toledo,Stephania Martins Bezerra,Fernando Augusto Soares,Fabiana Baroni Makdissi 대한외과학회 2017 Annals of Surgical Treatment and Research(ASRT) Vol.92 No.5
Sentinel lymph node biopsy has been developed as the standard of treatment in breast cancer. Status of axillary sentinel lymph node is known to be a significant prognostic factor. Nevertheless, involvement of an intramammary lymph node with metastasis in breast cancer is a rare radiological and clinical presentation, and with extracapsular extravasation even more uncommon. Historically, reported series of patients with intramammary lymph node diagnosed by final histological examination are small in number and clinical significance of metastasis is still unclear. Here, we report a case of conservative breast cancer surgery with 3 intramammary sentinel lymph nodes containing metastasis and extracapsular extravasation. After multidisciplinary consensus, the patient was surgically reapproached with mastectomy. Even though the 3 intramammary sentinel lymph nodes were positive for metastases, pathology examination did not reveal any signs of malignancy in the mastectomy specimen.