Review of Ammonia-Based Hydrogen Production

Yongha Park,Unho Jung,Keeyoung Koo 한국신재생에너지학회 2022 AFORE Vol.2022 No.9

Putative association of <i>SMAPIL</i> polymorphisms with risk of aspirin intolerance in asthmatics

Yongha Kim, Jason,Kim, Jeong-Hyun,Park, Byng-Lae,Sub Cheong, Hyun,Sook Park, Jong,Soo Jang, An,Uh, Soo-Taek,Choi, Jae-Sung,Kim, Yong-Hoon,Kim, Mi-Kyeong,Choi, Inseon S.,Heon Cho, Sang,Whui Choi, Byoun Informa Healthcare 2010 The Journal of asthma Vol.47 No.9

<P><I>Background.</I> Aspirin-intolerant asthma (AIA), as a clinical syndrome caused by aspirin, is characterized by lung inflammation and reversible bronchoconstriction. Recently, the altered trafficking and diminished airway reactivity have been implicated in allergic airway remodeling. The stromal membrane-associated protein 1-like (SMAP1L) exerts common and distinct functions in vesicle trafficking including endocytosis. The disturbance of pulmonary surfactant synthesis has been elucidated to be associated with asthma experimentally. Moreover, in alveolar type II (ATII) cells that synthesize pulmonary surfactant, alterations of clathrin-dependent endocytosis cause disturbance at the surfactant function, suggesting that SMAP1L, which directly interacts with clathrin, could be associated with asthma and related phenotypes. <I>Objective.</I> To verify our hypothesis that <I>SMAP1L</I> could play a role in the development of AIA, this study investigated associations between single-nucleotide polymorphisms (SNPs) of the <I>SMAP1L</I> gene and AIA. <I>Methods.</I> We conducted an association study between 19 SNPs of the <I>SMAP1L</I> gene and AIA in a total of 592 Korean subjects including 163 AIA and 429 aspirin-tolerant asthma (ATA) patients. Associations between polymorphisms of <I>SMAP1L</I> and AIA were analyzed with sex, smoking status, atopy, and body mass index as covariates. <I>Results.</I> Logistic analyses revealed that three common polymorphisms, <I>rs2982510</I>, <I>rs2294752</I>, and <I>rs446738</I>, were putatively associated with the increased susceptibility to AIA (<I>p</I> = .003, <I>p</I><SUP>corr</SUP> = .004, OR = 0.24, 95% CI = 0.09-0.62 for <I>rs2982510</I> and <I>rs2294752</I>; <I>p</I> = .008, <I>p</I><SUP>corr</SUP> = .03, OR = 0.44, 95% CI = 0.24-0.80 for <I>rs446738</I>, in the recessive model). In addition, <I>rs2982510</I> and <I>rs2294752</I> were significantly associated with the fall of forced expiratory volume in 1 s (FEV<SUB>1</SUB>) by aspirin provocation (<I>p</I> = .001, <I>p</I><SUP>corr</SUP> = .04 in the recessive model for both SNPs). <I>Conclusions.</I> Our findings suggest that <I>SMAP1L</I> might be a susceptible gene to AIA, providing a new strategy for the control of aspirin intolerance.</P>

Adsorption isotherms of CO2, CO, N2, CH4, Ar and H2 on activated carbon and zeolite LiX up to 1.0 MPa

Park, Yongha,Moon, Dong-Kyu,Kim, Yo-Han,Ahn, Hyungwoong,Lee, Chang-Ha Springer-Verlag 2014 Adsorption Vol.20 No.4

저농도 수소 혼합 가스의 고순도화를 위한 압력 순환식 흡착공정 개발

박용하(Yongha Park),이창하(Chang-Ha Lee) 한국에너지기후변화학회 2023 한국에너지기후변화학회 학술대회 Vol.2023 No.5

분리수거를 위한 페트병 분리시스템의 구현

박용하(Yongha Park),박지훈(Jihoon Park),정호영(Hoyeong Chung),이주상(Joosang Lee),이중엽(Jungyeop Lee) 한국정보통신학회 2021 한국정보통신학회 종합학술대회 논문집 Vol.25 No.1

본 연구에서는 적외선 센서를 이용한 페트병 분리수거 시스템을 구현하였다. 제안된 시스템은 인식부, 제어부, 알람부 및 구동부로 구성된다. 인식부는 페트병을 감지해 페트병과 센서와의 거리를 측정하고 값을 추출하고 추출된 값을 표준 범위와 비교하여 값이 표준 범위를 벗어날 경우에는 제어값을 제어부에 전송하고, 특정범위를 넘어간 경우 라벨 혹은 뚜껑의 유무결과를 제어부에 전송한다. 제어부에서는 센서부로부터 전송받은 결과값에 따라서 수거함의 입구를 개방하거나 알람부를 제어하는 기능을 수행한다. 제안된 시스템 구현을 위하여 인식부는 적외선 센서로 구현하였고, 제어부는 C언어 기반의 아두이노 스케치 프로그램으로 제작하였다. 또한, 인식부와 제어부는 아날로그 신호를 이용하여 통신할 수 있게 하였다. 제안된 시스템은 정해진 알고리즘에 따라 페트병의 라벨과 뚜껑의 유무를 정확히 판단한 후 라벨 혹은 뚜껑이 부착되었을 때 수거함의 입구를 막는다. 국민 1인당 배출되는 폐기물의 양이 높고 재활용이 되지 않아 쓰레기의 대다수를 소각시키고 있는 상황에서 본 연구에서 제안한 시스템을 통하여 페트병의 재활용률을 높이기를 기대한다. In this study, a plastic bottle recycling bin system that utilizes an infrared sensor was implemented. The proposed system consists of a recognition unit, a control unit, an alarm unit, and a driving unit. The recognition unit detects the plastic bottle, measures the distance between the plastic bottle and the infrared sensor, extracts the value of the bottle, compares the extracted value with a standard range, and then transmits the control value to the control unit if the extracted value of the bottle is outside the standard range. In this case, the result of the presence or absence of a brand label or bottle cap is transmitted to the controller. The control unit opens the entrance of the recycling bin or alerts the alarm unit according to the result value transmitted from the sensor unit. In order to implement the proposed system, the recognition unit was implemented with an infrared sensor, and the control unit was made with an Arduino IDE controller, based on the C programming language. Additionally, the recognition unit and the control unit are able to communicate using analog signals. The proposed system accurately judges the presence or absence of a brand label and bottle cap of plastic bottles according to a predetermined algorithm. It then blocks the entrance of the recycling bin when a brand label or bottle cap is still attached. As the amount of waste discharged per person is relatively high and the majority of such waste is incinerated rather than recycled, the system proposed in this study is expected to increase the recycling rate of plastic bottles.

코로나19(COVID-19)의 초국가적 전파와 세계 항공 네트워크의 변화 간 연관성에 대한 시론적 연구 : 연결 중심성을 이용한 항공 네트워크의 전역적·지역적 변화 탐색

박용하(Yongha Park),손정웅(Jeongwoong Sohn) 한국공간환경학회 2020 공간과 사회 Vol.30 No.3

코로나19 팬데믹의 영향으로 인한 세계 항공시장의 침체가 지속되고 있다. 본 연구는 코로나19 확산에 따른 항공시장의 변화를 이해하기 위한 시론적 연구로서, 2020년 상반기 동안국가별 코로나19의 확산 양상과 동 기간 세계 항공 네트워크의 전역적·지역적 축소 양상을분석하고, 나아가 이 두 시공간 패턴 간 연관성을 탐색하고자 하였다. 이를 위해 ① K-평균 군집 분석을 이용하여 확진자 증가 추세가 유사한 국가들의 지역적 분포를 누적 확진자 규모와그 규모에 도달한 시기에 따라 단계적으로 살폈다. ② 네트워크 분석의 연결 중심성 지표 등을 이용하여 항공 네트워크의 시기별·지역별 차별적인 변화 추이를 분석하였다. ③ 마지막으로 군집 분석을 통해 도출된 확산 양상이 유사한 국가 군집 간 항공 네트워크의 연결 중심성감소 추이에 대한 비교 분석을 통해 두 시공간 패턴 사이의 연관성을 살폈다. 분석 결과, 지난상반기 동안 세계 항공 네트워크는 중·대형 허브들을 중심으로 연결성이 급속히 감소함에 따라 네트워크의 범위와 밀도가 축소되었음을 확인하였다. 또한, 지역 또는 국가 간 연결성의감소 시기와 정도에는 편차가 존재하고 있었다. According to the COVID-19 pandemic, global aviation market is becoming stagnant. This study is an early assessment to understand crucial impact of the disease propagation on the aviation market through analyzing degree centrality changes of airports in the World Air transport Network(WAN), in comparison to spreading patterns of the disease. We employ K-means clustering to figure out spatio-temporal phases of the disease spread across countries in the world. Then, we apply degree centrality measure of the network analysis to OAG airlines schedules data, in order to capture the temporal changes of degree centrality distribution. Finally, we examine differential patterns of degree centrality distributions across countries grouped by the spatio-temporal phases of disease spread patterns. As a result, we find that density and size of the WAN have rapidly decreased from January to June in 2020, mainly affected by decreasing connectivity of medium- and large-hubs. Furthermore, the decreasing connectivity patterns appear differentially among regions and countries, with respect to their fluctuating periods and levels.

중력 모형을 이용한 국제항공 네트워크와 GaWC 세계도시 분류 체계 간 연관성 탐색

박용하 ( Yongha Park ) 한국지리학회 2021 한국지리학회지 Vol.10 No.1

본 연구에서는 전 세계 주요 도시 간 국제항공 공급 양상과 GaWC(Global and World Cities Research Network)의 세계도시 분류 체계 간 연관성 탐색을 통해 국제항공 네트워크를 기반으로 구현된 세계도시 네트워크의 주요 특징들을 살펴보았다. 이를 위해 먼저 2010~2018년 두 초국가적 도시 네트워크 사례를 구성하는 주요 도시들의 분포 추이를 분석하였다. 또한 중력 모형을 이용하여 도시 간 국제항공 공급 양상에 인구, 1인당 GDP, 거리 요인과 함께 GaWC 세계도시 분류로부터 도출된 비즈니스 연결성과 도시 더미가 미친 영향을 파악하였다. 분석 결과는 다음과 같다. 첫째, 국제항공 네트워크를 구성하는 주요 도시들은 GaWC 도시 그룹에 비해 서유럽 분포 편중이 높게 나타났으며, 최상위 도시 그룹 내 중동·아시아 지역의 국제항공 거점 도시들과 기존 서유럽·북미의 중심 도시들 간 공급 규모 측면에서의 역전 현상이 나타나고 있었다. 둘째, 비즈니스 연결성은 인구, 1인당 GDP에 비해 국제항공 공급 양상에 미치는 영향이 컸으며, 시간에 따라 그 우위가 더욱 강해지고 있음을 확인하였다. 마지막으로 GaWC 주요 도시들의 국제항공시장 내 공급 우위 수준과 GaWC 도시 계층 간에는 차이가 존재하였으며, 항공시장의 다극화 추세에 따라 소수의 최상위 도시들이 지녔던 공급 우위가 시간에 따라 점차 약화되고 있음을 발견하였다. 본 연구는 국제항공과 GaWC를 통해 구현된 세계도시 네트워크 사례 간 비교분석을 통해 세계도시 네트워크의 다각성과 역동성을 고찰하였다는 점에서 의의가 있다. The main purpose of this study is to characterize the world city network (WCN) through exploring the relationship between international air transport networks (IATN) and GaWC (Global and World Cities Research Network) world city classification. We explore spatio-temporal distributions of major cities constituting those trans-national city networks from 2010 to 2018, in order to find distinctive characteristics of WCN represented by IATN. Then, we employ the gravity model, adapted for air transport, to examine factors influencing city-pair interactions through IATN, including not only city population, GDP per capita, distance but also business connectivity and city dummies derived from the GaWC world city groups. The main finding are as follows. First, major cities in IATN are more highly concentrated on Western Europe than the GaWC cities caused by varying aviation market structures across regions. Within the first-tier city group in IATN, there is also a hierarchy shift between cities in developed- and emerging-regions. Second, business connectivity has a greater impact on international interaction patterns than population and GDP per capita, and its impact has been even stronger over time. Lastly, we observe the weakening dominant position of top-tier cities, in terms of international market supply. Also there are differences in city hierarchy system between IATN and GaWC, partly affected by the multipolarization trend in the global aviation market. This study confirms the dynamics and diversity of the world city network through the comparative analysis between the two empirical transnational city network cases.

수소압축기용 Metal Diaphragm의 steel301 소재에 대한 피로특성

박용하(Yongha Park),송준혁(Junhyuk Song),이현우(Hyunwoo Lee) 한국자동차공학회 2010 한국자동차공학회 학술대회 및 전시회 Vol.2010 No.11

Metal diaphragm is widely used for hydrogen pressure vessel. and it is very important about fatigue and fracture field because it has a reciprocating motion. Therefore, it is necessary to obtain fatigue characteristic and reliability about the material of diaphragm. The objective of this study is to estimate the diaphragm’s mechanical property and fatigue characteristic by 25kN Elastomer testing equipment. This test was implement on the 50㎐ and R(stress ratio)=0.1 and acquired S-N curve for each stress level conditions. From the test, fatigue limit cycle satisfies the condition of 356.93㎫

인간동력항공기 Main Spar 경량 설계

박진호(Jinho Park),김현덕(Hyunduk Kim),김용하(Yongha Kim),박정선(Jungsun Park) 항공우주시스템공학회 2013 항공우주시스템공학회 학술대회 발표집 Vol.2013 No.10

Potential Association of <i>DDR1</i> Genetic Variant with FEV₁ Decline by Aspirin Provocation in Asthmatics

Kim, Jason Yongha,Kim, Jeong-Hyun,Park, Byung-Lae,Pasaje, Charisse Flerida A.,Bae, Joon Seol,Uh, Soo-Taek,Kim, Yong-Hoon,Kim, Mi-Kyeong,Choi, Inseon S.,Cho, Sang Heon,Choi, Byoung Whui,Park, Jong Sook Informa Healthcare 2012 The Journal of asthma Vol.49 No.3

<P><I>Background.</I> The <I>discoidin domain receptor tyrosine kinase 1</I> (<I>DDR1</I>) is positioned within the major histocompatibility complex (MHC) region which plays an important role in the immune system. In addition, DDR1 has been elucidated to be downregulated during the epithelial-mesenchymal transition of bronchial epithelium. <I>Objective.</I> To investigate the potential genetic associations between <I>DDR1</I> and aspirin-exacerbated respiratory disease (AERD), this study conducted association studies of <I>DDR1</I> single nucleotide polymorphisms (SNPs) with AERD and the obstructive symptom of forced expiratory volume in 1 s (FEV<SUB>1</SUB>) decline after aspirin provocation. <I>Methods.</I> Nine common SNPs were genotyped in 93 AERD patients and 96 aspirin-tolerant asthma (ATA) controls. The genotype distributions of all loci were in Hardy-Weinberg equilibrium (HWE; <I>p</I> > .05). <I>Results.</I> In the results of logistic analyses using age, sex, smoking status, and atopy as covariates, <I>DDR1 rs1264320</I> in the intronic region showed a potent association signal with FEV<SUB>1</SUB> decline by aspirin provocation in asthmatics of this study even after corrections for multiple testing (<I>p</I> == .003 and corrected <I>p</I> == .01). However, the variants of <I>DDR1</I> were not significantly associated with the AERD development (corrected <I>p</I> > .05). On further comparison of FEV<SUB>1</SUB> decline by aspirin provocation between AERD and ATA, the variant <I>rs1264320</I> was found to be associated with the FEV<SUB>1</SUB> decline of ATA rather than AERD. <I>Conclusion.</I> Despite the need for further functional evaluations and replications, we conclude that <I>DDR1</I> polymorphisms are not likely to contribute to predispositions of AERD, but may be potentially associated with FEV<SUB>1</SUB> decline by aspirin provocation in asthmatics.</P>