아파트 주차수요 변화에 관한 연구 : 대구지역을 중심으로 Focused on Daegu city area

박찬돈,홍성우,이상관 경운대학교 산업기술연구소 2001 産業技術硏究論文誌 Vol.3 No.2(C)

For recent 30 years, the ratio of car possessions is rapidly increased according to economic growth. So, nowadays, most of cities and apartment complexes have suffered from traffic and parking problems. The purpose of this study is to provide proper future parking demand at apartment complex in Daegu city by we get the analysis date of the present parking demand. The method of this study is based on field survey of parking demand at apartment complexes in daegu city. The result of this study is as follows; 1) The parking demand has a limit. 2) The old aged apartment complex has more parking problems than the new apartment complex.

의약품의 효능별 안전성·유효성 평가에 관한 조사연구(Ⅰ) : 항균제 Antiboiotics

박윤주,최기환,김동섭,박인숙,정면우,임화경,오우용,강주희,박찬웅,김주일 식품의약품안전청 2001 식품의약품안전청 연보 Vol.5 No.-

새로운 물질이 개발되어 신약으로 탄생하기까지 많은 시간과 노력, 예산이 필요하다. 최근, 우리 나라에서도, 신약캐발이 어릴고 힘든 분야이지만 새로운 신약개발을 총해 얻어지는 분가가치가 막대함을 인식, 연구에 박차를 가하 있는 실정이다. 본 연구는, 의약품 개발 선진국인 미국 FDA에서 발행하는 참고자료 중 항균제 임상편가에 대한 가이드라인 및 주요 임상적응증별 항균제 기발(지역사획회득성 폐렴, 원내감염성 계렴, 급성기관지염의 2차세균감염, 만성기지염의 급성세균성 악화, 연쇄구균에 의한 인두영 및 편도염 , 단순성 요로감염증, 복합성 요로감염증 및 신우신영, 급성 세균성 부비동옆, 항 바이러스제 개발시 전임상단계에서 고려사항, 항 바이러스제 허가와 된련 잉상적 고려사항, 카레타 괸련 혈류감염)에 있어서의 파이드라인 등의 자료를 소개함으로져, 향후 제약사의 항균제 신약개발 및 허가 신청된 의악품의 전임상차료 및 잉상시험자료의 검토 평가업무에 참고자료로 활용될 수 있을 것이다. Changing or unclear interpretations of clinical trial data needed to demonstrate the effectiveness and safety of antimicrobial drug products have a times led to confusion and frustration on the part of both applicants and division of these drug products reviewers. The FDA published guidance on desing clinical protocols, implementing, and analyzing data from clinical trials for antimicrobial drug products has been presented and additional companion guidances introduced specific issues to individual infections. This document provides applicants and reviewers with minimal information appropriate for the clinical development of routine antimicrobial drug products and identifies issues common to many antimicrobial drug applications. The agency can use the kind of information to determine whether the antimicrobial drug product under study is safe and effective in the treatment of the specific infection studied.

間歇的 運動에 의한 脫水 및 水分攝取의 生理的 效果

朴哲浩,朴吉俊,李相于,金永明,朴贊熙,玄松子,呂南會,朴相甲,金榮俊 東亞大學校附設스포츠科學硏究所 1989 스포츠科學硏究論文集 Vol.7 No.-

This study aims at revealing the physiological responses of dehydration (DH) and rehydration (RH) in intermittent exercises at the work intensity of 70% HR max. First, with general student public, three times of exercise (each for 20 minutes) at the given work intensity were taken, with a break for 25 minutes respectively. Their heart rate, rectal temperature and plasma electrolyte concentration both DH and RH were measured. Second, in two groups of athletes and non-athletes, 9 rounds of exercise (for 100 minutes) and 8 breaks (for 60 minutes) were taken, with RH forced 10 times to compensate for the subjects' water loss. Their change in sweat loss and plasma electrolyte concentration as well as the IVDP(Intensive Voluntary dehydration Phenomenon) were experimented. The summary of this research follows. 1) Mean heart rate and rectal temperature in intermittent exercises were higher at DH than at RH, growing up at the increasing level of DH. 2) RH saw no change in the plasma concentration of Na+, K+ and Cl-, while DH observed a significant increase. 3) HCO₃made a significant decrease at DH before growing up. 4) Mg++ had no change, while Ca++ increased significantly at RH and DH. 5) Lactate showed an increase with significance at RH and DH, especially greater at DH. 6) Osmotic pressure increased meaningfully at DH. 7) Anion gap increased significantly at DH and RH. 8) On the other hand, when the forced RH was held, the group of athletes had greater sweat loss per body surface area than that of non-athletes. 9) The athletes' plasma concentration of Na+ and Cl- revealed a clear decrease. 10) There was seen no significant change in the plasma concentration of K+, Mg++ and Ca++ in both groups. 11) The IVDP occurred at the RH of 2.3ℓfor athletes and more than 2.5ℓfor no-athletes.

NW6005를 이용한 발신자 번호 추적 장치 개발

이다한,박찬진,박찬국,이성철,박민경,윤병우 경성대학교 공학기술연구소 2012 공학기술연구지 Vol.18 No.-

NW6005의 칩을 이용하여 발신자 번호 데이터를 추적하는데 성공하였고 그 뿐만 아니라 두 개 이상의 전화에서 발신자 번호 데이터를 수신하더라도 데이터가 깨지지 않고 제대로 수신하는 알고리즘을 구상하였고 그에 대한 실험은 성공적이었으며 또한 전화 통신중의 오류에 대한 문제도 해결하였다. 최종적으로 4개의 전화선에서 하나 또는 동시에 발신자 번호를 추적하여 시리얼 통신으로 데이터를 전송시키는 장비를 개발하였다.

폐결핵 환자 혈청에서 수용성 Interleukin 2 수용체 및 Adenosine Deaminase 활성도에 관한 연구

고정희,박성규,백상현,박찬권,박병수,안진영,최우석,박정규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

Interleukin-2 (IL-2) induces T cell proliferation in an autocrine manner and provides a means by which antigen triggered T cells can be clonally expanded in vitro. During the following activation, the activity of IL-2 is mediated by specific high affinity IL-2 binding membrane receptors which are expressed shortly after activation. In this process, a 42 KD-fragment (soluble IL-2R) is continuously cleaved off and circulates as a soluble marker of T lymphocyte activation. Elevated level of soluble IL-2R has been identified in the serum of patients with malignant autoimmune and allergic disorders, systemic parasitic infection, undergoing graft versus host disease, acute or chronic lymphocytic leukemia and HIV-infection. ADA (adenosine deaminase) completes the process of differentiation of T cell and is essential for progression of T cell maturation. Therefore level of ADA is to correlated with magnitude of T cell immune response. The fact that expression of sIL-2R and ADA activity increases in peripheral blood T-lymphocytes of patients with active pulmonary tuberculosis suggests that T cell activation might have a major role in the pathogenesis of pulmonary tuberculosis. In order to evaluate the T cell immune response in pulmonary tuberculosis, we measured the serum concentration of sIL-2R and ADA activity in 17 patients with current pulmonary tuberculosis, 10 chronic inactive pulmonary tuberculosis, 10 as normal controls. (1) Current pulmonary tuberculosis had significantly higher levels of sIL-2R (237.24±95.47)when compared with those of inactive tuberculosis (78.6±11.06). and the control (68.17±15.4) group. (2) ADA activity in current pulmonary tuberculosis was significantly increased (34.41±20.63) when compared with those of inactive tuberculosis (24.7±14.36) and control (17.65± 5.94) group. (3) There was good correlation between sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group. (4) sIL-2R concentration and ADA activity was decreased significantly 6 months after anti-tuberculosis drug medication. In conclusion, sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group was increased when compared with those of inactive pulmonary tuberculosis and the control group. By the way, T cell mediated immune response was enhanced in current pulmonary tuberculosis, but in inactive chronic pulmonary tuberculosis who had treated by antituberculosis drug medication, the concentration of sIL-2R and ADA activity was nearly normal.

장거리선수의 운동시 심전도 파고 및 시간간격에 관한 고찰

박찬희,김우규 東亞大學校 附設 스포츠科學硏究所 1995 스포츠科學硏究論文集 Vol.13 No.-

This study Attempts to that Heart Functional know Long-distance Athlete by Electrocardiographic Time Interval and Wave Amplitudes. Fourteen Male Subjects aged Between 21-23years were devided into Athete and Control Groups. Pre-execise, Execise and Recovery Mode was performed on a Bicycle-ergometer. Load of Execise Mode was 1Kp/3min, 2Kp/3min, 3Kp/3min. ECG's were traced in LoadⅡ,V₁ and V? to Pre-execise, Execise and Recovery. ECG interval were measured from LeadⅡ and ECG amplitudes from LoadⅡ, V₁ and ??. The results Obtained are Aummarized as Follow : 1. ECG interval ; 1) The R-R interval at Pre-exercise Mode was 1.121±0.181sec in Athlete group and 0.862±0.148sec Control group. Athlete group was Sinus Bradycardia. 2) The P-R interval at Pre-exercise Mode was 0.174±0.018sec in Athlete group and 0.487±0.048sec Control group. 3) The QRS interval at Pre-exercise Mode was 0.093±0.009sec in Athlete group and 0.018±0.009sec Control group. 4) The QRS interval at Pre-exercise Mode was 0.512±0.077sec in Athlete group and 0.409±0.019sec Control group. 2. ECG amplitude ; 1) The P wave Amplitude at Pre-exercise Mode was 0.871±0.304mm Athlete group and 0.801±0.162mm Control group. The Amplitude was Increaser the Athlete group than Control group. 2) The R wave Amplitude at Pre-exercise Mode was 26.61±4.63mm Athlete group and 19.84±3.87mm Control group. The Amplitude was Increaser the Athlete group than Control group. 3) The S wave Amplitude at Pre-exercise Mode was 13.32±2.14mm Athlete group and 10.61±1.03mm Control group. The Amplitude was Increaser the Athlete group than Control group. Exercise Mode was enlarged Change Form Time Interval and Amplitude in Control group and Recovery Mode Time Interval and Amplitude in Athlete group rapided Rahabilition and the Sum of Amplitude in ?? and SV₁ in Athlete group was 40.00mm suggesting a Left Ventricular Hypertrophy.

완제품에 대한 수요가 Compound Poisson 과정에 따라 발생하는 CONWIP System의 성능분석

박찬우,신경화,이효성 한국경영과학회 2002 한국경영과학회 학술대회논문집 Vol.- No.1(2)

In this study we consider a flow-line CONWIP System with Compound Poisson Demands. The processing times of each workstation follow a Coxian-2 distribution. The demands that are not satisfied instantaneously are either backordered or lost according to the number of backordered demands that exist at their arrival instants. For this system we develop an approximation method to obtain the performance measures such as steady state probabilities of the number of parts at each station, the average number of backordered demands and the proportion of the lost demands. Comparisons with simulation have shown that the approximate method provides fairly good results.

분편 인플루엔자백신(split influenza vaccine)의 임상효과 및 면역원성에 관한 연구

우흥정,김동림,정희진,천병철,이주연,안정배,김지희,박찬,신영규,김우주,김민자,박승철 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.1

목적 : 아단위 인플루엔자 백신 접종 후 백신의 인플루엔자 예방효과, 인플루엔자 방어 항체형성, 인플루엔자 백신의 안전성을 조사하고자 하였다. 방법 : 총 571명을 대상으로 인플루엔자 백신 접종을 하였고, 이들 접종자에서 인플루엔자 양질환의 이환을 조사하여 인플루엔자 백신의 인플루엔자예방효과를 알아보았고, 백신의 접종 전 및 접종 4주 후 혈청에서 혈구응집억제물(Hemagglutination Inhibition : HAI) 항체 검사를 실시하여 백신의 방어항체생성을 조사하였고, 백신의 안전성을 알아보기 위해 백신접종 후 1주일 이내의 부작용을 조사하였다. 결과 :백신 접종군과 백신 비접종군에서 인플루엔자 양 질환의 이환을 조사한 결과 접종군 28.35%, 비접종군 35.88%으로 나왔으며, p 값이 0.001로 통계적으로 접종군에서 유의하게 낮았고, 인플루엔자 양 질환의 예방 효과는 20.97%를 보였다. 백신의 방어항체 형성의 평가를 위해 유럽의 인플루엔자 백신 허가 기준을 조사하였는데 B/Guangdong/5/94균주의 백신접종 후 항체가 40이상의 비율을 제외한 다른 기준은 모두 만족 시켰다. 부작용은 전체 조사자 521명중 149명(29%)으로 주로 접종 부위의 국소 부작용을 호소했고, 전신 부작용은 2% 내외였으며 특별히 심각한 부작용은 발견되지 않았다. 결론 : 분편 인플루엔자 백신은 인플루엔자양질환의 예방과 방어항체생성에 효과 있으며 안전한 것으로 사료된다. Background : The safety and effectiveness of influenza vaccine are well known in developed country. The influenza vaccination has been recommended as one of the tentative immunization schedule for indicated persons since 1997 in Korea. But there are still no available data about them, even though nearly 5 million doses of influenza vaccine were used in 1997-1998 season. So it is immediately needed to investigate the safety. efficacy and immunogenicity of influenza vaccine among Korean. Methods : We studied the clinical efficacy of influenza vaccine by monitoring Occurrence of influenza-like illness in influenza risk group(vaccination ; 300, non-vaccination; 215) from December in 1997 to March in 1998. We used the split quadrivalent influenza vaccine containing 15 microgram of hemagglutinin of A/Beijing/262/95(HlNl), A/Wuhan/359/95(H3N2), B/Mie/1/93 and B/Guangdong/5/94. Hemagglutination inhibition(HA1) antibody titers were determined before immunization and 1 months after vaccination And we evaluated adverse effect of influenza vaccination at 7 days after vaccination. Results : Influenza vaccination was associated with si@icant reductions in influenza-like spptoms(vaccination group; 28.35%, non-vaccination group, 35.88%, p=0.001). The preventive effect of influenza-like i3lne.s among influenza risk goup was 20.97%. And immunogenicity of influenza A and B exceeded all of the European licensure criteria for immunogenicity except postvaccination proportion of titers 240 of B/Guangdong/5/94 strain. And the adverse effects were mainly local injection site problem and no serious adverse effect was noted. Conclusion : Split influenza vaccine is safe, inmunogenic and eff'tive in influenza risk group in Korea.

근관치료용 전기모터의 회전 안정성 평가

박세희,서현우,홍찬의 大韓齒科保存學會 2010 Restorative Dentistry & Endodontics Vol.35 No.4

수종의 근관치료용 전기모터들의 반복사용과 시간에 따른 회전속도의 변화를 비교하여 근관치료용 전기모터의 회전 안정성을 평가하고자 하였다. 시간에 따라 변화하는 실제회전속도 및 전압과 전류를 측정하고, Student t-test를 통한 실제회전속도와, 반복측정분석을 통한 상관관계를 비교분석 하였다. 동일 종류의 전기모터들 사이의 모든 측정 결과들은 차이를 보이지 않았다. 모든 전기모터에서 반복사용과 시간의 흐름에 따른 회전속도의 변화는 차이를 보이지 않았다. 이상의 결과로, 본 실험에 사용된 모든 전기모터는 일정한 회전속도를 유지해야 하는 회전 안정성의 조건에 충족됨을 알 수 있으며, 반복사용과 시간에 따른 신뢰성 있는 회전속도와 안정적인 전압 및 전류의 유지가 가능하리라 생각된다. The purpose of this study was to evaluate a rotational stability of endodontic electronic motors by comparing the changes of rotational speed, depending on the number of usages and with/without static load. Twelve new endodontic electronic motors were used in this study. Non contact type digital tachometer was used for measuring the rotational speed of handpiece. True RMS Multimeter was used for measuring the voltages and the electric currents. All measurements were recorded every 10 seconds during 10 minutes and repeated 9 times. Five repetition was done per each electronic motor. To statistical analysis, student t-test, repeated measures and Scheffe's post-hoc tests were performed. In the same motor group, there was no significant difference in all measurements. In all groups, there was no significant difference in the amount of rotational speed changes depending on the number of usages and with/without static load. In the limitation of this study, the results showed that all kinds of endodontic electronic motors in this study had an established rotational stability. Therefore they could be safely used in root canal treatment with areliable maintenance of rotational speed, regardless of the number of usages and with/without load.

白雲山 成熟林木伐採作業地에서 伐出直後 野生動物과 土壤微小動物相의 變化

禹保命,朴在鉉,朴贊烈 서울大學校 農業生命科學大學 農業開發硏究所 1995 서울대농학연구지 Vol.20 No.2