모 형광등업체에 있어서의 공기중 수은농도 및 요중 수은량 조사

박승회,김광종,장성훈,차철환 大韓産業醫學會 1989 대한직업환경의학회지 Vol.1 No.2

In order of interpret the relationship among many variables, urinary mercury and the same time mercury concentration in air were measured for 254 workers of a fluorescent lamp manufacturing factory. And monthly consumption amounts, numbers of monthly producing fluorescent lamps, numbers of inferior lamps numbers of breakage lamps, numbers of vacuum pumps and frequencies of mercury infusion were also investigated from January 1988 to March in 1989. The results were as follows; 1. On the mercury concentration in air by producing line and by working site, all of them were exceed the threshold limit value (0.05mg/㎥). 2. The highest mercury concentration in air by sampling was found at the floor of workplace (0.334mg/㎥) and next were at vacuum exhaustion prmp (0.183mg/㎥), and breathing zone of workers(0.103mg/㎥) in order. 3. The highest mean of the mercury concentration in urine by producing line was the automatic exhausting line (80.8㎍/1) and next were high speed exhausting line (72.4㎍/1), and Manual exhausting line (35.8㎍/1) in order. Distribution of workers of the mercury concentration in urine more than 200㎍/1 by working site was the highest (10%) in the vacuum exhaustion pump part and next were sealing part (6.6%), packing part (4.6%), and stem part (4.1%) in order. 4. The correlation coefficient between mercury concentration in urine and in air was the highest(0.302) and next were numbers of breakage lamps (0.223), frequencies of mercury infusion (0.223), numbers of inferior lamps (0.205) in order.

급성 신부전증을 초래한 Wegener씨 육아종증 1례

박일,임영국,최성도,임현성,정종훈,문철웅 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.1

호흡기 증상과 급성신부전증이 발생된 환자에서 혈액검사, 혈청학적 검사, 방사선학적 검사, ANCA test 및 신생검을 통하여 Wegener씨 육아종증을 경험하였기에 문헌 고찰과 함께 보고하는 바이다. 본질환이 재발하는 경우는 cyclophosphamide에서 azathioprine으로 치료약을 바꾸었을때나 특히 ANCA 반응이 양성으로 지속시 발생한다. Godman과 Churg는 상기도의 괴사성 육아성 병변, 하기도의 괴사성 혈관염, 국한성 신사구체염을 진단의 지표로 삼았다. 특히 상기도 점막의 생검 소견상 괴사성 육아성 혈관염이 보이면 일단 본 증을 의심하고 폐 생검과 신 생검이 필요로 한다. Wegener's Granulomatosis is an uncommon disease which is characterized by granulomatous vasculitis of both lung and kidney. Although the cause is unknown, it's suggesting that disordered immunity with both antibody and cell-mediated tissue damage occurs. The disease affects patients of any age. Characteristic clinical manifestations are diverse but in clude saddle nose deformity, sinusitis, productive coughing, myalgia, fever etc. Characteristic laboratory abnormalities include elevated ESR, neutrophilic leukocytosis, anemia and positive test for ANCA test. Renal biopsy is important for diagnosis. The treatment of choice is a combination of corticosteroid and cytotoxic agent. A53-year-old woman was admitted to our hospital because of productive coughing, short of breathing, oliguria, nausea, and vomiting. Three months ago, she was suffered from general weakness, poor appetite, tingling sensation on extremity, and loosely stool. Twenty days ago, above symptoms were aggravated, she admitted local clinic. Six days ago, because of CBC showed anemia , she was done transfusion. During transfusion, she was developed urticaha then productive coughing, dyspnea, increased serum BUN and creatinine levels. She was transferred to our hospital under the impression of ARF. On the admission, she was chronic ill-looking appearance with pale conjunctiva, tachypnea, dyspnea, and cold sweating. We have checked the patient by CBC, serum and serologic test, X-ray, ANCA test, renal biopsy. With renal biopsy microscopic examination study revealed necrotizing vasculitis, We treated a combination therapy with methyl-PDS and cyclophosphamide. She had a good response. So we report wegener's granulomatosis with the review of relevant literature.

제주시 해안일주도로변 건축물의 형태구성적 특성에 관한 연구

박철민,김성훈 제주대학교 공과대학 첨단기술연구소 2004 尖端技術硏究所論文集 Vol.15 No.2

Although buildings by the roadside represent the landscape environment, they have many problems. The government and public management have developed a new block of buildings without any careful and long-term reviews. An owners indifference and the economical situation also have forced these problems. This study, by getting hold of problems with the case of seaside road in Jeju is purposed to propose the improvement of the visual quality of the landscape view, for raditional direction in planning buildings and fournitures on streets, based on the visual characteristic. The result of this study is as follows 1) As improving defects in the system, the seaside road is to be created into the space of life and the street landscape. 2) By the form-type composed in various methods, the identity of the seaside road is to be formed. and general type is the favorite one since it is easy to design the homogeneous space. 3) Contents, to controll the number and type of signs to compose the seaside road is to be included in the ordinance.

Thin 실리콘 기판을 이용한 MEMS 소자의 패키징

박윤권,김용국,김훈,이윤희,김철주,주병권 경북대학교 센서기술연구소 2002 센서技術學術大會論文集 Vol.13 No.1

도로변 건축물의 경관요소에 미치는 영향에 관한 연구 : 제주시 해안일주도로를 중심으로

박철민,김성훈 제주대학교 공과대학 첨단기술연구소 2004 尖端技術硏究所論文集 Vol.15 No.1

Although the coastal area of Jeju has already been developed, it has high pressure and demands for development continually increasing due to the increase of tourism and leisure activities. Therefore, the purpose of this study is to present objective guidance for the planning of the buildings on the seaside road with a view which have the largest impact on coastal landscape in order to enhance its visual quality. The results of this study are as follows : 1) It is chief element to make guidance for the use and planning of buildings in the conservation of the coastal landscape. 2) The D/H ratios which immediately influence an angle of elevation are different one another for the whole street. To ensure a sense of openness for the landscape, it is needed to maintain under 27° angle of elevation, which demands 1~3 D/H ratio. 3) It is important to make 2.4 visual blockage ratio for whole street, but the actual condition is 4.48 ratio on average. To bring down the visual blockage ratio, the W/D ratio needs to be regulated. 4) Various techniques are also needed for lively building styles going with coastal landscape.

요중 Protein 및 N-Acetyl-β-Glucosaminidase의 생물학적 변동에 관한 연구

朴園,李恩一,車喆煥,張聖薰 고려대학교 의과대학 1992 고려대 의대 잡지 Vol.29 No.1

The purpose of this study was to evaluate the biological variations of N-acetyl-β-glucosaminidase activity, beta-2 microglobulin, alpha-1 microglobulin, total protein, and microalbumin in spot urine specimens, all of which have been used as a screening test for the evaluation of renal dysfunction. The study was conducted from June to August of 1991, with analysis-evaluation of the 24-hour urine specimens with that of 3 spot-urine specimens and first morning specimen. A total of 14 healthy college student volunteers (non-exposed group) and 42 workers exposed to carbon disulfide (exposed group)were selected as the study subjects. The results were as follows ; 1. The mean values of N-acetyl-β-glucosaminidase activity and alpha-1 microglobulin in 24 hour urine specimens in the exposed group were higher than those in the non-exposed group. 2. Coefficient of variation among spot urine specimens of N-acetyl-β-glucosaminidase in exposed group was the lowest among the results of 5 different types of urine tests. 3. The correlation coefficients between the values in 24 hour urine specimens and those in spot urine specimens were above 0.9 for total protein. microalbumin, and alpha-1 microglobulin. The correlation coefficients between the NAG activities in 24 hour urine specimens and those in spot urine specimens were relatively high. 4. Of the total 25 workers who showed a higher N-acetyl-β-glucosaminidase activity than the reference data for the 24 hour urine specimens, the number of workers excessive reference data for the spot urine specimens was 23(92%), and 22(88.9%) for the first morning urine specimens.

백서에서 신 허혈성 손상에 미치는 칼슘 길항제의 효과

문철웅,정종훈,박천국,이승일,배학연,장경식,김만우,정춘해,홍순표,이병래,김호중 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

Renal ischemia is one of the most common causes of acute renal failure. Four factors related to the pathogenesis of acute renal failure are vasoconstriction, decreased glomerular filtration rate, tubular back leak of filtrate, and intratubular obstruction. The cellular response to renal ischemic insults include decreased content of adenosine trihosphate, lipid peroxidation induced membrane degradation, alteration in cellular pH, and calcium or phospholipase induced mitochondrial dysfunction. Much attention has been given to the role of increased cellular calcium as a pathogenetic contributor to cell injury during ischemia. Author studied the protective effects of calcium antagonists on cellular injury during renal ischemia in rat. To investigate the protective role of these agents, author measured the amount of malondialdehyde(MDA) and the enzyme activities of free radical scarvengers-superoxide dismutase(SOD), catalase and glutathione peroxidase from non-pretreated group and calcium antagonists pretreated groups in control, ischemia and reflow subgroups. The results were summerized as follows: 1) The amount of MDA in non-pretreated group was higher in the reflow compared with the control(<p<0.01). But, in all pretreated groups, there was no statistically difference in the amount of MDA. 2) The SOD activity in non-pretreated group was lower in both the ischemia and the reflow compared with the control (P<0.05). But, in both verapamil and trifluoperazine-pretreated groups, there was no statistically difference in the SOD activity. 3) Both catalase and glutathione peroxidase activities in non-pretreated group were lower in both the ischemia and the reflow compared with the control (P<0.05). But in all pretreated groups, there was no statically difference in both catalase and glutathione peroxidase activities. These results suggest that free radical mediated ischemic injury by renal artery clamp in rat can be protected by intraperitoneal pretreatment with calcium antagonists. As trifluoperazine has a protective effect in renal ischemia, the calcium activated calmodulin dependent enzyme may play a role in renal ischemic injury.

중학교 응급처치 교육의 실태 조사 연구

김훈철,김세환,박기동,김승재 강원대학교 체육과학연구소 2000 江原大學校附設體育科學硏究所論文集 Vol.- No.23

The purpose of this study was to investigate the current status of first aids program in the safety education that was a part of the physical education curriculum in middle school. And this study is to supply the fundamental data for efficient safety education. The data was gathered with questionnaires given to 145 physical education teachers in Kangwon Province. Teachers think that the first aids education is essential in middle school curriculum. Taking considerations of the numerous accidents in society. This need will provide a remedy for any emergent situation and enlighten the safety-first-mind to protect against accidents. However, it is difficult to determine that efficient and good quality of first aids education is implemented in middle school. Based on the data, followings are some findings from the result; a) teachers lack experiences with first aids education, b) teachers are not equipped with sufficient theoretical and practical knowledge about first aids, and c) classroom teaching materials for first aids education are not furnished in the school at all. To suggest based on the above conclusions, the information about first aids must be employed in depth during the training period for present teachers along with learning physical education teachers so as to develop the theoretical knowledge and applicable capability about the education. Schools must stock adequate teaching materials for first aids education, and seek for effective and high quality education.

설측 브라켓 부착을 위한 기준평면 설정에 관한 3차원 유한요소법적 연구

김선화,박수병,양훈철 대한치과교정학회 2006 대한치과교정학회지 Vol.36 No.1

교정치료 영역에서 성인들의 심미적인 요구도가 증가되면서 설측 교정치료는 여러 가지 단점에도 불구하고, 가장 심미적이라는 이유로 많은 주목을 받아왔지만 실제 치아이동을 결정지을 수 있는 브라켓을 부착하는 기준평면의 위치에 대해서는 거의 보고된 바가 없다. 이에 본 연구는 실제 브라켓이 부착되는 평면의 상하 평행이동이나 기울기 변화에 따라 치아이동 양상이 어떻게 변화되는지 알아보고, 바람직한 전치부 치체이동을 얻기 위해서 힘의 적용점을 어디에 두어야 하는지, 그리고 전치부에 어느 정도 모멘트를 부여해야 하는지 알아보고자 3차원 유한요소법을 이용하여 치아 변위 및 응력분포를 비교 분석하였다. 실험 결과 설측 브라켓 부착평면을 치은연쪽으로 평행이동 혹은 회전이동 시키고 견인하였을 경우, 절단연쪽으로 이동시켰을 때와 비교했을 때 비조절성 설측 경사이동이 감소하기는 하였으나 상하악 전치부 치아들의 설측경사 양상은 지속되었으며, 이러한 양상은 견치 브라켓의 hook 길이를 증가시켜도 계속 나타났다. 이와는 달리 설측 중심평면에 브라켓을 부착하고 각 치아별로 모멘트를 부여하였을 경우 설측 방향으로 개개 치아들의 치체이동이 발생하여 설측 교정치료 시 효과적인 전치부 치아의 후방견인이 가능함을 알 수 있었다. This study was performed to investigate the location of the ideal bracket positioning plane in lingual orthodontics using the three-dimensional finite element method. Displacement of the anterior teeth were evaluated according to the vertical and the angular movements of the bracket positioning plane. To achieve the ideal movement of anterior teeth in the lingual central plane, the location of the force application point and the amount of the moment applied to the four incisors were evaluated. As the bracket positioning plane was moved parallel toward the incisal edge, uncontrolled tipping and extrusion of the maxillary and the mandibular incisors were increased. But lingual tipping of the crown was decreased in the maxillary and the mandibular canines. As the bracket positioning plane was inclined toward the incisal edge, lingual tipping was increased in the 6 anterior teeth and extrusion of incisors and intrusion of the canine was also increased. As the retraction hook of the canine bracket was elongated, lingual tipping and extrusion of the central incisor and mesial movement and extrusion of the lateral incisor were increased. In the canine, mesial and labial movements of the crown were increased. When the moment was applied to the 4 incisors of the maxillary and the mandibular arch in the lingual central plane, 280 gf-mm in the maxillary central incisor, 500 gf-mm in the maxillary lateral incisor, 170 gf-mm in the mandibular central incisor and 370 gf-mm in the mandibular lateral incisor produced bodily movement of the individual tooth.

비정상 질확대경검사 소견을 보이는 환자에서 환상투열요법의 직접적 적용에 관한 연구

우헌탁,이철민,박교훈,조용균,최훈,김복린,이홍균 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.2

Objective: Large Loop Excision of the Transformation Zone (LLETZ) has been widely used for evaluating cervical dysplasia/cancer. We performed this study to evaluate if colposcopically suspected cervical high-grade dysplasia or cancer could be directly evaluated and treated with LLETZ. Methods: 93 women who were scheduled for colposcopic evaluation because of an abnormal cervical cytology report were included in the study in Sanggye Paik Hospital from Jan to Dec 2001. Mean age of the study population was 38.6±9.0. colposcopy directed punch biopsy was not performed and histologic diagnosis was made by LLETZ. Sensitivity and specificity of colposcopic evaluation was calculated and compared with those of cervical cytology. Results: On histopathological examination by LLETZ, 11(11.8%) patients had invasive cancers including 3(3.2%) adenocarcinomas. The sensitivity and specificity of colposcopy for the detection of cervical dysplasia or cancer was 71.7% and 72.3% respectively, wile those of cytology was 56.5% and 74.5% respectively. Conclusion: LLETZ may be adequately performed for the diagnosis and treatment of cervical dysplasia/cancer based on the results of pap smear and colposcopy without punch biopsy. Cost benefit might be anticipated while cost-effectiveness analysis is necessary in the future.