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류창곤,김석종,김문관,박정식 제주대학교 해양연구소 1997 해양자원연구소연구보고 Vol.21 No.-
In order to increase fishing efficiencies of the fyke net used in the coast of Cheju Island water tank experiment was caried out entering and escaping behavior using nets that were reduced to 1/20 of the size of fyke net and were improved to have antrance structure, and Mackerel Scomber japonicus as experimental fish. The results of measurement are as follows: 1. Fish school behavior in the main net was showed two different patterns: swimming in a circle in the right space of the main net and swimming back and forth in ellipse in the right and left space. 2. The swimming speed of mackerel school was 24.9. 12.6 and 32.0cm/sec in the center space. right space of main net and in the mouth. 3. The entering rate of fish school was 40% in net with 35cm length of the upper and funnel net in the mouth of fyke model net and 49% in conventional type fyke model net. 4. The escaping rate of fish school was 10% in net with 35cm length of the upper and funnel net in the mouth of fyke model net and 69% in conventional type fyke model net. 5. The remain rate of fish school was 90% in net with 35cm length of the upper and funnel net in the mouth of fyke model net and 31% in conventional type fyke model net.
金麟坤,朴昌鎭 慶北大學校 1992 論文集 Vol.52 No.-
The purpose of this study is to analyse the structure and Strength of North Korean Military forces and through which provide a theoretical basis for the improvement of relationship between South and North Korea. The study shows the following findings. (1) The North Korean military forces can be defined in various terms as Kim il-sung's forces, forces of the Labor Party, revolutionary forces, and the forces for economic development. However, the most significant feature of the North Korean military forces is that it is central to Kin Il-Sung's political and legal power. (2) The ultimate goal of the North Koran military forces lies in the communization of the whole Korean peninsula. (3) As manifested in the decree of the Labor Party, military forces are "armed forces of the Party", thus the Party exercises full control over the military forces. (4) Till the present time organization of the North Korean military forces are based on the conventional weapons system. The study concludes that the North Korean military forces are under the full control of Kim Il-Sung and its strength is on the increase.
具硏健,金長福,朴俊烈 弘益大學校 1980 弘大論叢 Vol.12 No.-
A motor speed controller is presented using digital techniques to measure and a microprocessor to compare and correct motor speed. Proportional control is used for acceleration and dynamic braking for deceleation, together with the slope of acceleration Intergral control is used for preventing from OFFSET and divergence. The rising time is 2∼3 seconds and the steady state error is less than 0.5% of setting speed.
서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1997)
김재홍,문득곤,김정수,김용준,임동진,박상훈,김희성,이민수,송기훈,김갑형,김형석,성소영,이인섭,김석우,황지환,조창근,김경문,부태성 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.3
Background : In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. Objective & Methods : For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1997. 99 strains of N. gonorrhoeae were isolated, among which 45(45.5%) were PPNG. Conclusion : The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 45.5% in 1997.
Jeong, Young-Il,Seo, Dong-Hyuk,Kim, Don-Gon,Choi, Chang-Yong,Jang, Mi-Kyeong,Nah, Jae-Woon,Park, Yoon-Kyung The Polymer Society of Korea 2009 Macromolecular Research Vol.17 No.7
In this study, methotrexate (MTX)-encapsulated polymeric micelles using methoxy poly(ethylene glycol) (MPEG)-grafted chitosan (ChitoPEG) copolymer were prepared. The MIX-incorporated polymeric micelles of ChitoPEG copolymer has a particle size of around 50-100 nm. In 1H nuclear magnetic resonance (NMR) study, the specific peaks of MTX disappeared in heavy water ($D_2O$) and only the specific peak of MPEG was observed, while all of the peaks were confirmed in dimethyl sulfoxide (DMSO). These results indicated that MTX was complexed with chitosan and then formed an ion complex inner-core of the polymeric micelle in an aqueous environment. The drug contents of the polymeric micelle were around $4{\sim}12%$ and the loading efficiency of MTX in the polymeric micelles was higher than 60% (w/w) for all of the formulations. The cytotoxicity of MIX and MTX-incorporated polymeric micelle against CT26 tumor cells was not significantly changed.
Effect of combined anti-PD-1 and temozolomide therapy in glioblastoma
Park, Junseong,Kim, Chang Gon,Shim, Jin-Kyoung,Kim, Jong Hoon,Lee, Hoyoung,Lee, Jae Eun,Kim, Min Hwan,Haam, Keeok,Jung, Inkyung,Park, Su-Hyung,Chang, Jong Hee,Shin, Eui-Cheol,Kang, Seok-Gu Informa UK (TaylorFrancis) 2019 Oncoimmunology Vol.8 No.1
Chang, Eun-Sook,Kim, Seong-Gon,Khil, Lee-Yong,So, Dhong-Su,Chang, Tong-Shin,Kim, Jin-Hyoung,Jeon, Sun-Duck,Moon, Chang-Kiu,Park, Kwang-Sik The Korean Society of Environmental Toxicology 1996 환경독성보건학회지 Vol.11 No.3
In this study we investigated the effect of hydroxybrazilin on glutathione depletion induced by BrCCl$_3$ and menadione in cultured hepatocytes to understand the cellular mechanisms of hepatoprotective effect of hydroxybrazilin. Hydroxybrazilin alone had no effect on total glutathione level and the ratio of reduced glutathione/total glutathione (GSH/(GSSG+GSH)). BrCCl$_3$ dramatically decreased total glutathione level and hydroxybrazilin significantly prevented glutathion depletion by BrCCl$_3$. The ratio of GSH/(GSSG+ GSH) was also decreased by BrCCl$_3$ and recovered by hydroxybrazilin treatment. Menadione decreased total glutathione level and the ratio of GSH/(GSSG+GSH) but hydroxybrazilin showed no significant effects on menadione-induced glutathione depletion. These data suggest that hydroxybrazilin might prevent the hepatotoxicity induced by chemicalderived radicals but not the toxicity linked with oxidative stress.
Risk Prediction Model for Patients with Hepatocellular Carcinoma Undergoing Radiofrequency Ablation
( Chang Gon Kim ),( Hye Won Lee ),( Seung Up Kim ),( Jun Yong Park ),( Do Young Kim ),( Sang Hoon Ahn ),( Kwang-hyub Han ),( Hye Jin Choi ),( Gyoung Min Kim ),( Man Deuk Kim ),( Sung Il Park ),( Jong 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1
Aims: We aimed to establish a simple-to-use risk prediction model for patients with hepatocellular carcinoma (HCC) undergoing radiofrequency ablation (RFA). Methods: Patients receiving RFA as the first-line therapy between 2005 and 2014 were selected from the database (n = 757). The study population was randomly assigned into the derivation (n=505) and the validation (n=252) cohorts. Multivariate Cox-regression analysis for disease-free survival (DFS) was used to select the variables to generate the risk prediction model in the derivation cohort and then, the prognostic performance was assessed in the validation cohort. Results: From multivariate Cox-regression analysis, tumor size, tumor number, baseline alpha-fetoprotein (AFP) level, baseline protein induced by vitamin K absence/antagonist-II (PIVKA-II) level and ascites were selected. The scores were allocated for each variable as follows; 0, 2, and 5 for tumor size<2 cm, 2~3 cm, and ≥3 cm, respectively, 0, 2, and 4 for tumor number 1, 2, and 3, respectively, 0 and 1 for AFP<20 ng/m and AFP≥20 ng/mL, respectively, 0 and 1 for PIVKA-II< 40 mAU/mL and PIVKA-II≥ 40 mAU/mL, respectively, and 0 and 1 for presence and absence of ascites, respectively. The risk prediction model was defined as the sum of each score assigned to each key variable. Time-dependent areas under receiver-operating characteristic curves of the risk prediction model for DFS at 3 and 5 years were 0.758 and 0.766 in the derivation cohort and 0.848 and 0.853 in the validation cohort, respectively. According to the score of the risk prediction model, patients were stratified into three groups: the low-risk (score 0~1), the intermediate-risk (score 2-3), and the high-risk (score > 4) group, respectively. In the training cohort, the low-risk group had the longest median DFS (50.1 months), followed by the intermediate-risk group (24.8 months), and the high-risk group (8.9 months). Compared with the low-risk group, the intermediate-risk group (hazard ratio [HR] 2.419, P < 0.001) and the high-risk group (HR 8.499, P < 0.001) retained the significant higher risk of recurrence or death. Similar results were obtained in the validation cohort. Conclusions: A simple-to-use risk prediction model for patients with HCC undergoing RFA might be helpful in appropriate prognostic stratification and guidance for decision of further treatment strategies.