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- 저자 : Oh Choon Kwon(권오춘) (검색결과 4 건)
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배지훈,권오춘,이섭,조창호,Bae, Chi-Hoon,Kwon, Oh-Choon,Lee, Sub,Cho, Chang-Ho 대한흉부심장혈관외과학회 2001 Journal of Chest Surgery (J Chest Surg) Vol.34 No.5
Synovial sarcoma is a malignant soft tissue tumor that primarily occurs in the praarticular regions, especially in the knee. They are composed of keratin-positive epithelial cells and vimentin-positive spindle cells. We report a 76 year old woman with a primary synovial sarcoma in the mediastinum that had severe adhesion to the right side of pericardium. Primary synovial in the midiastinum is extremely rare and this is the first case reported in the Korean literature. The mass including the pericardium was resected and the defect was closed with Gore-Tex patch. The patient is well and free of disease 6 months after the operation.
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강형석,이섭,권오춘,안욱수,배지훈,Kang, Hyong-Seok,Lee, Sub,Kwon, Oh-Choon,Ahn, Wook-Su,Bae, Chi-Hoon 대한흉부심장혈관외과학회 2000 Journal of Chest Surgery (J Chest Surg) Vol.33 No.8
Descending necrotizing mediastinitis(DNM) is one of the most lethal form of mediastinitis originating from an oropharyngeal infection. It requires an early and aggressive sugical treatment, but the operative approach and optimal form of mediastinal drainage remains controversial. We report a case of DNM in a 45-year-old male who underwent right cervicomediastinotomy to drain the deep neck space, upper mediastinum and anterior mediastinal drainage was accomplished through a subxiphoid approach. After this procedure, he steadily improved and was dischrged on hospital day 36. We report this case with a brief review of the literature.
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권오춘,안욱수 대구효성가톨릭 대학교 1997 연구논문집 Vol.54 No.2
Primary spontaneous pneumothorax has an annual incidence of 9 cases per 100,000 populations, especially high incidence in young adults. Thoracoscopic surgery is not new, but its applications to chest surgery have been more increasing with advanced video technology and instrumentation. We performed 15 cases of bullectomy using video-assisted thoracoscopy(VATS) for patients of pneumothorax. The mean age of patients was 25.1±7.6 years old, 105.5±40.1 minutes of mean operation times, and 3.2±1.9 days of postoperative tube indwelling time. Postoperative complications were persistent air leakage in one case, which was converted to open thoracotomy later, and recurrence of pneumothotax in one case. Video-assisted thoracoscopic bullectomy is effective alternative to thoracotomy for treatment of pneumothorax in terms of short hospital stay, less morbidity, low rate of recurrence, less pain, and good cosmetic results. But objective comparison with mini-thoracotomy will be needed in many aspects.
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톨루엔 취급 근로자의 ALDH2 Genetic Polymorphism에 따른 뇨중 마뇨산 배설량
김창윤,정종학,권오춘,김성용,이중정,주리 大韓産業醫學會 1997 대한직업환경의학회지 Vol.9 No.2
In this study we evaluated the effects of the genetic polymorphism of aldehyde dehydrogenase2 (ALDH2) on the toluene metabolism and determined biological exposure indices(BEIs) for toluene by the genotypes of ALDH2. The study subject were 77 men workers who are handling toluene in a video tape manufacturing factory and a textile company. Through the face-to-face interview, the information about smoking and drinking behavior was obtained. For determination of ALDH2 polymorphism, 5ml of venous blood sample was obtained from each subject after informed consent. DNA was extracted from the buffy coat and ALDH2 genotyping were performed using a polymerase chain reaction(PCR) method. The genotype of ALDH2 was classified into the homozygous genotype of normal ALDH2(NN), and the heterozygous genotype of normal and inactive ALDH2(ND), and homozygous genotype of an inactive ALDH2(DD). The concentration of hippuric acid (HA), the main metabolite of toluene, was determined in urine specimens collected at the end of shift, corrected with creatinine(HA/C), and compared with BEI for toluene, which is 2.5 g/g creatinine. The personal exposure level of toluene were monitored, using personal air sampler and analyzed by gas chromatography. The frequencies of the three genotypes in this study subject were, NN : 45 (58.4%), ND : 26 (33.8%) and DD : 6 (7.8%), and frequencies of the genotypes in the middle or heavy toluene exposure workers were not significantly different from those in the mild toluene exposure workers. The frequencies of the DD type of ALDH2 was lower among alcohol drinkers than among non-drinkers. The urinary HA concentration of DD group was significantly lower than that of the NN or ND group, which suggests that the HA formation from toluene decreased in DD group. Regression lines were used to estimate the BEIs of the NN, ND, and DD groups. NN : y = 0.0085x + 0.23, r = 0.90 ND : y = 0.0074x + 0.21, r = 0.85 DD : y = 0.0041x + 0.82, r = 0.83 The three regression lines revealed that the estimated urinary HA concentration of NN, ND, and DD groups at 377 mg/㎥ toluene (TLV-TWA) exposure were 3.43, 3.00, and 2.37g/g than that of the ACGIH BEI (2.5 g/g creatinine) ; however, the HA level of DD group was lower than the BEI. These results suggest that the ACGIH BEI is not adequate to estimate the toluene exposure of the NN, ND and DD groups at the same time. Based upon these results, a new BEI for ALDH2 deficient workers may be necessary.
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