Performance Evaluation on Applicability of Q-STM method to the ATM network

Noriaki Kamiyama,Hideki Tode,Miki Yamamoto,Hiromi Okada,Hiromasa Ikeda 한국통신학회 1995 Asia-Pacific Conference on Communications Vol.2 No.1

Nerve-sparing radical hysterectomy: time for a new standard of care for cervical cancer?

Noriaki Sakuragi 대한부인종양학회 2015 Journal of Gynecologic Oncology Vol.26 No.2

Nerve-sparing radical hysterectomy: time for a new standard of care for cervical cancer?

Monte Carlo simulations evaluating shielding parameters of empirical formula for heavy ion accelerator facility

Noriaki Nakao,Hee-Seock Lee 대한방사선방어학회 2010 대한방사선방어학회 학술발표회 논문요약집 Vol.2010 No.11

RT(Robot Technology)-Component and its Standardization

Noriaki Ando,Takashi Suehiro,Kosei Kitagaki,Tetsuo Kotoku 제어로봇시스템학회 2006 제어로봇시스템학회 국제학술대회 논문집 Vol.2006 No.10

Mechanisms of Osteoclastogenesis in Orthodontic Tooth Movement and Orthodontically Induced Tooth Root Resorption

Noriaki Ono 대한골대사학회 2023 대한골대사학회지 Vol.30 No.4

Orthodontic tooth movement (OTM) is achieved by the simultaneous activation of bone resorption by osteoclasts and bone formation by osteoblasts. When orthodontic forces are applied, osteoclast-mediated bone resorption occurs in the alveolar bone on the compression side, creating space for tooth movement. Therefore, controlling osteoclastogenesis is the fundamental tenet of orthodontic treatment. Orthodontic forces are sensed by osteoblast lineage cells such as periodontal ligament (PDL) cells and osteocytes. Of several cytokines produced by these cells, the most important cytokine promoting osteoclastogenesis is the receptor activator of nuclear factor-κB ligand (RANKL), which is mainly supplied by osteoblasts. Additionally, osteocytes embedded within the bone matrix, T lymphocytes in inflammatory conditions, and PDL cells produce RANKL. Besides RANKL, inflammatory cytokines, such as interleukin-1, tumor necrosis factor-α, and prostaglandin E2 promote osteoclastogenesis under OTM. On the downside, excessive osteoclastogenesis activation triggers orthodontically-induced external root resorption (ERR) through pro-osteoclastic inflammatory cytokines. Therefore, understanding the mechanisms of osteoclastogenesis during OTM is essential in reducing the adverse effects of orthodontic treatment. Here, we review the current concepts of the mechanisms underlying osteoclastogenesis in OTM and orthodontically induced ERR.

Scintillation properties of Pr-doped Li2O-GeO2 glasses

Noriaki Kawaguchi,Takayuki Yanagida 한양대학교 세라믹연구소 2019 Journal of Ceramic Processing Research Vol.20 No.5

We have investigated scintillation properties of the Pr-doped Li2O-GeO2 glasses. From the transmittance spectra, absorption bands due to 4f-4f transition of Pr3+ ions were observed. The samples showed the X-ray induced radioluminescence peaks originating from the 4f-4f transitions of the Pr3+ ion. The scintillation decay times were from 2.07 to 3.12 µs which are acceptable values for the scintillator. The Pr-doped Li2O-GeO2 glasses can be regarded as the candidate for the scintillation materials.

Nerve-sparing radical hysterectomy in the precision surgery for cervical cancer

Noriaki Sakuragi,GenMurakami,Yosuke Konno,Masanori Kaneuchi,Hidemichi Watari 대한부인종양학회 2020 Journal of Gynecologic Oncology Vol.31 No.3

Precision cancer surgery is a system that integrates the accurate evaluation of tumor extension and aggressiveness, precise surgical maneuvers, prognosis evaluation, and prevention of the deterioration of quality of life (QoL). In this regard, nerve-sparing radical hysterectomy has a pivotal role in the personalized treatment of cervical cancer. Various types of radical hysterectomy can be combined with the nerve-sparing procedure. The extent of parametrium and vagina/paracolpium excision and the nerve-sparing procedure are tailored to the tumor status. Advanced magnetic resonance imaging technology will improve the assessment of the local tumor extension. Validated risk factors for perineural invasion might guide selecting treatment for cervical cancer. Type IV Kobayashi (modified Okabayashi) radical hysterectomy combined with the systematic nerve-sparing procedure aims to both maximize the therapeutic effect and minimize the QoL impairment. Regarding the technical aspect, the preservation of vesical nerve fibers is essential. Selective transection of uterine nerve fibers conserves the vesical nerve fibers as an essential piece of the pelvic nervous system comprising the hypogastric nerve, pelvic splanchnic nerves, and inferior hypogastric plexus. This method is anatomically and surgically valid for adequate removal of the parametrial and vagina/paracolpium tissues while preserving the total pelvic nervous system. Local recurrence after nerve-sparing surgery might occur due to perineural invasion or inadequate separation of pelvic nerves cutting through the wrong tissue plane between the pelvic nerves and parametrium/paracolpium. Postoperative management for long-term maintenance of bladder function is as critical as preserving the pelvic nerves.

Three-Dimensional Evaluation of Innominate Bone Rotation in Female Patients with Developmental Dysplasia of the Hip

Noriaki Sako,Nobuhiro Kaku,Yoshiki Kitahara,Yuta Kubota,Hiroaki Tagomori,Hiroshi Tsumura 대한정형외과학회 2022 Clinics in Orthopedic Surgery Vol.14 No.2

Background: Patients with developmental dysplasia of the hip (DDH) are known to have abnormal pelvic morphologies; however, rotation of innominate bone features remains unclear. Thus, we investigated innominate bone rotation in patients with DDH by measuring the associated angles and distances using three-dimensional (3D) computed tomography. Methods: We defined four straight lines in pelvic 3D models: from the anterior superior iliac spine to the posterior superior iliac spine, from the anterior inferior iliac spine to the posterior inferior iliac spine, from the pubic tubercle to the ischial spine, and from the pubic tubercle to the ischial tuberosity. Similarly, we measured the angles formed by these lines using the vertical axis of the anterior pelvic plane on the horizontal plane and the horizontal axis on the sagittal plane. Additionally, we measured the distances between the femoral head centers and the acetabular centers in the coronal plane. Results: The difference in internal rotation angle between the superior and inferior parts of the iliac bone was significantly lower, by approximately 1.7°, in the DDH group than in the control group (p = 0.007); the difference between the inferior and superior parts of the ischiopubic bone was significantly higher, by approximately 1.5°, in the DDH group (p < 0.001). In the sagittal plane, the sum of the superior aspect of the iliac bone and the inferior aspect of the ischium was significantly lower in the DDH group (p = 0.001) than in the control group. The distances between the femoral heads and the acetabula were significantly greater in the DDH group than in the control group (p = 0.03, p < 0.01, respectively). Conclusions: Patients with DDH had a more internally rotated ilium and ischiopubic bone than normal individuals; however, it should be emphasized that internal rotation was reduced near the acetabulum, and the acetabulum was shifted laterally. Similarly, it was shown that patients with DDH had different rotations of the ilium and ischiopubic bone in the sagittal plane.

Estimation of Shielding Parameters for the Heavy Ion Accelerator Facility Using a Monte Carlo Simulation

Noriaki Nakao,이희석,조운갑 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.22

For a conceptual shielding design of the Korea Rare Isotope Accelerator (KoRIA) project, the shielding parameters for the source terms and the attenuation lengths for a simple exponential formula were determined based on simulations using the PHITS Monte Carlo code. Simulations were performed for angular and energy spectra of secondary neutrons from an iron target of full stopping thickness or a thin graphite target bombarded by heavy ions of ^(238)U, ^(86)Kr, ^(48)Ca (200 ∼ 270 MeV/u) and protons (600 MeV). Using the thus obtained neutron energy spectra for various angles, we also simulated attenuations of high-energy neutrons through 8-m-thick shields of concrete or iron. By fitting the exponential formula to the attenuation profiles, we obtained shielding parameters for various combinations of projectile, target, angle and shielding material. The parameters were summarized for a point beam loss and for a uniform beam loss along the accelerator beam line. Appropriate shielding thicknesses of concrete and iron could be estimated comparatively easily for various conditions in the heavy ion accelerator facility.

Is the Iliac Wing Curved Inward in Patients with Developmental Dysplasia of the Hip?

Noriaki Sako,Nobuhiro Kaku,Hiroaki Tagomori,Hiroshi Tsumura 대한정형외과학회 2021 Clinics in Orthopedic Surgery Vol.13 No.4

Background: There is a paucity of studies on the iliac curvature in developmental dysplasia of the hip (DDH). Here, we examined the iliac curvature in DDH using three-dimensional computed tomography. Methods: We allocated cases with a center-edge angle of < 20° to the DDH group (55 cases) and cases with a center-edge angle of > 25° to the control group (57 cases) and measured the straight line (line A) between the anterior and posterior superior iliac spines. We examined which part of the iliac bone line A passes through and classified the results into 4 categories (type A, inside the iliac bone; type B, through the iliac bone; type C, outside the iliac bone; and type D, both inside and outside the iliac bone) to evaluate the iliac wing curvature. After measuring the area and internal surface of the iliac wing using line A, we examined the correlation between these values, the interspinous distance, the superior iliac angle, and the center-edge angle. Results: Distributions of the four types were compared between the two groups; there was no significant difference. The length of the portion of line A inside the ilium and the area formed by line A and the iliac wing, which shows the degree of iliac wing curvature, were not significantly different between the groups. There were no correlations between these values and the center-edge angle; however, there were weak positive correlations among the interspinous distance, the superior iliac angle, and the centeredge angle. Conclusions: The inward nature of the iliac bone in patients with DDH is mainly due to the internal rotation of the entire iliac bone and less likely due to the curvature of the iliac bone.