Acute Systemic Infusion of Bupropion Decrease Formalin Induced Pain Behavior in Rat

Naderi, Somayyeh,Pakdel, Firouz Ghaderi,Osalou, Mostafa Ashrafi,Cankurt, Ulker The Korean Pain Society 2014 The Korean Journal of Pain Vol.27 No.2

Background: The chronic pain can disturb physical, psychological, and social performances. Analgesic agents are widely used but some antidepressants (ADs) showed analgesia also. Bupropion is using for smoke cessation but it can change morphine withdrawal signs such as pain. This study tested the acute systemic effect of bupropion on formalin induced pain behavior in rats. Methods: Wistar male healthy rats were divided into 7 groups (control, sham, and 5 treated groups with 10, 30, 90, 120, and 200 mg/kg of bupropion, i.p.). The bupropion injected 3 hours prior to formalin induced pain behavior. Formalin (50 ${\mu}l$, 2.5%) was injected subcutaneously in dorsal region of right hindpaw in all animals. Nociceptive signs were observed continuously on-line and off-line each minute. Common pain scoring was used for pain assessment. Results: The analysis of data by one-way ANOVA showed that bupropion can reduce pain scores in the second phase but not in first phase. Bupropion decreased the licking/biting duration significantly in first and second phase of formalin test. Conclusions: The results showed that bupropion has analgesic effects at systemic application. The change of second phase of the pain behavior was significant and it revealed that central mechanisms involve in bupropion analgesia.

The effect of SiO2 and TiO2 nanoparticles on physical properties of SrFe12O19 nanoparticle

Ehsan Naderi,Mahmoud Naseri,Dariush Souri 한국물리학회 2018 Current Applied Physics Vol.18 No.4

In order to obtain SrFe12O19 nanoparticles, thermal treatment method was employed, and afterwards SiO2 and TiO2 nanoparticles were embedded in SrFe12O19 matrix SrFe12O19 nanoparticles. The SiO2 and TiO2 nanoparticles' effects were set in SrFe12O19 matrix and experimental techniques which include, transmission electron microscopy (TEM), x-ray diffraction (XRD), fourier transform infrared spectroscopy (FT-IR), x-ray analysis (EDX) and field emission scanning electron microscope (FESEM) were used in studying the physical properties of the prepared nanoparticles. The precise DASF method (derivation of absorption spectrum fitting) was employed in examining the optical properties. The addition of SiO2 and TiO2 nanoparticles to SrFe12O19 matrix resulted in the reduction of energy band gap values in compare with the SrFe12O19 nanoparticles. The chemical analysis of SrFe12O19/SiO2, SrFe12O19 nanoparticles, and SrFe12O19/TiO2 nanocomposites was carried out using energy dispersion X-ray analysis (EDX). Ferromagnetic behaviors were demonstrated by SrFe12O19 nanoparticles, SrFe12O19/SiO2 and SrFe12O19/TiO2 nanocomposites, and the behaviors were validated through the use of a vibrating sample magnetometer (VSM). A wasp-waist was observed through hysteresis loop of SrFe12O19/SiO2 nanocomposites, implying the presence of the two magnetic phases; soft and hard ferromagnetic.

Timing, Optimal Dose and Intake Duration of Dietary Supplements with Evidence-Based Use in Sports Nutrition

( Alireza Naderi ),( Erick P. De Oliveira ),( Tim N. Ziegenfuss ),( Mark E. T. Willems ) 한국운동영양학회 2016 Physical Activity and Nutrition (Phys Act Nutr) Vol.20 No.4

[Purpose] The aim of the present narrative review was to consider the evidence on the timing, optimal dose and intake duration of the main dietary supplements in sports nutrition, i.e. β-alanine, nitrate, caffeine, creatine, sodium bicarbonate, carbohydrate and protein. [Methods] This review article focuses on timing, optimal dose and intake duration of main dietary supplements in sports nutrition. [Results] This paper reviewed the evidence to determine the optimal time, efficacy doses and intake duration for sports supplements verified by scientific evidence that report a performance enhancing effect in both situation of laboratory and training settings. [Conclusion] Consumption of the supplements are usually suggested into 5 specific times, such as pre-exercise (nitrate, caffeine, sodium bicarbonate, carbohydrate and protein), during exercise (carbohydrate), post-exercise (creatine, carbohydrate, protein), meal time (β-alanine, creatine, sodium bicarbonate, nitrate, carbohydrate and protein), and before sleep (protein). In addition, the recommended dosing protocol for the supplements nitrate and β-alanine are fixed amounts irrespective of body weight, while dosing protocol for sodium bicarbonate, caffeine and creatine supplements are related to corrected body weight (mg/kg bw). Also, intake duration is suggested for creatine and β-alanine, being effective in chronic daily time < 2 weeks while caffeine, sodium bicarbonate are effective in acute daily time (1-3 hours). Plus, ingestion of nitrate supplement is required in both chronic daily time < 28 days and acute daily time (2- 2.5 h) prior exercise.

Investigating Effect of ECAP Process on Corrosion Behavior of WE43 Magnesium Alloy in Simulated Body Fluid

E. Naderi,A. Davoodi,H. R. Jafarian 대한금속·재료학회 2023 METALS AND MATERIALS International Vol.29 No.11

Corrosion of WE43 magnesium alloys after equal-channel angular pressing (ECAP) process with one pass (1P), two pass(2P), three pass (3P) and four pass (4P) were investigated as a function of immersion time in 37 ± 2 °C simulated body fluid(SBF) to imitate body corrosion environment utilizing AC electrochemical impedance spectroscopy (EIS), Potentiodynamicpolarization (PDP) curves, SEM and optical microscopy techniques in addition to EDS analysis. Among the samples, 2P and3P samples illustrated better corrosion resistance not only among all the samples but also as a function of elapsed immersiontime in SBF media. Better corrosion resistance was related to precipitation of β particles with fair and large volume fractionwhich served as cathodic reaction sites. Uniform distribution of the reactions not only reduce the severity of micro-galvaniccorrosion but also by passing immersion time, anodic reaction dissolved magnesium substrate next to and around β phaseand separate them from the surface which resulted loss of cathodic sites and reduction of corrosion. Additionally, the morphologyof the β phase was changed from needle-like in 1P & 2P samples to spherical one in 3P & 4P samples. It is believeddiminished corrosion resistance of 4P samples not only among the ECAPed samples but also as a function of immersiontime, were related to coarsening of spherical β phase. In another word, corrosion reactions amplified and continued whileseparation of the phase from the surface was delayed due to its larger size.

The effect of talc on the reaction sintering, microstructure and physical properties of Al2TiO5 based ceramics

Golsa Naderi,Ali ShokuhFar,Rahim Naghizadeh,S. Atashgar,Hamid Reza Rezaie 한양대학교 세라믹연구소 2009 Journal of Ceramic Processing Research Vol.10 No.1

Tialite (Al2TiO5) is a ceramic material of very low thermal expansion coefficient, excellent thermal shock resistance, high refractoriness and good corrosion resistance. However, industrial applications of this material are hindered by two major limitations: decomposition to its parent oxides, alumina and rutile between 800 and 1280 oC and its low thermal mechanical properties. In the present study addition of talc with a good stabilizing effect has been studied on aluminum-titanate (tialite)- based ceramics. X-ray diffraction (XRD) and scanning electron microscopy (SEM) were used to characterize the effect of talc on phase evolutions, sintering, and the microstructure of aluminum-titanate, and also density measurements were performed after sintering. The results showed that the presence of talc reduces the unreacted alumina and rutile significantly. The formation of Mg0.3Al1.4Ti1.3O5 and other solid solutions of MgO and aluminum-titanate were observed. Tialite (Al2TiO5) is a ceramic material of very low thermal expansion coefficient, excellent thermal shock resistance, high refractoriness and good corrosion resistance. However, industrial applications of this material are hindered by two major limitations: decomposition to its parent oxides, alumina and rutile between 800 and 1280 oC and its low thermal mechanical properties. In the present study addition of talc with a good stabilizing effect has been studied on aluminum-titanate (tialite)- based ceramics. X-ray diffraction (XRD) and scanning electron microscopy (SEM) were used to characterize the effect of talc on phase evolutions, sintering, and the microstructure of aluminum-titanate, and also density measurements were performed after sintering. The results showed that the presence of talc reduces the unreacted alumina and rutile significantly. The formation of Mg0.3Al1.4Ti1.3O5 and other solid solutions of MgO and aluminum-titanate were observed.

A fast damage detecting technique for indeterminate trusses

Arash Naderi,Mohammad Reza Sohrabi,Mohammad Reza Ghasemi,Babak Dizangian 국제구조공학회 2020 Structural Engineering and Mechanics, An Int'l Jou Vol.75 No.5

Detecting the damage of indeterminate trusses is of major importance in the literature. This paper proposes a quick approach in this regard, utilizing a precise mathematical approach based on Finite Element Method. Different to a general two-step method defined in the literature essentially based on optimization approach, this method consists of three steps including Damage-Suspected Element Identification step, Imminent Damaged Element Identification step, and finally, Damage Severity Detection step and does not need any optimizing algorithm. The first step focuses on the identification of damage-suspected elements using an index based on modal residual force vector. In the second step, imminent damage elements are identified among the damage-suspected elements detected in the previous step using a specific technique. Ultimately, in the third step, a novel relation is derived to calculate the damage severity of each imminent damaged element. To show the efficiency and quick function of the proposed method, three examples including a 25-bar planar truss, a 31-bar planar truss, and a 52-bar space truss are studied; results of which indicate that the method is innovatively capable of suitably detecting, for indeterminate trusses, not only damaged elements but also their individual damage severity by carrying out solely one analysis.

Application of Inverse Geochemical Modeling for Predicting Surface Water Chemistry in Ekbatan Watershed, Hamedan, Western Iran

Elahe Naderi Peikam,Mohsen Jalali 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

Total and Partial Updating Technique: A Swift Approach for Cross-Section and Geometry Optimization of Truss Structures

Arash Naderi,Mohammad Reza Sohrabi,Mohammad Reza Ghasemi,Babak Dizangian 대한토목학회 2020 KSCE JOURNAL OF CIVIL ENGINEERING Vol.24 No.4

In this paper, a novel two-phase method called Total and Partial Updating Technique, is employed for the cross section and geometry optimization of truss structures. The goal of optimizing such structures is to minimize their weights under natural frequency constraints. In Total and Partial Updating Technique, in order to find the global optimum point, only the best two existed solution points at each repetition move together in the search space defined in each phase. Each time, the first phase is destined to find a solution near the global optimum point although searching in the unfeasible region. In the second phase, it is forced jumping into the feasible region to reach the global optimum point. The comparison of the results with those in the literature on two numerical examples demonstrates that due to its relatively significant low computational costs and its assured non-violated constrained optimum solutions at the end of the process, the method may be considered as more reliable and efficient technique on such problems.

Acute Systemic Infusion of Bupropion Decrease Formalin Induced Pain Behavior in Rat

( Somayyeh Naderi ),( Firouz Ghaderi Pakdel ),( Mostafa Ashrafi Osalou ),( Ulker Cankurt ) 대한통증학회 2014 The Korean Journal of Pain Vol.27 No.2

The chronic pain can disturb physical, psychological, and social performances. Analgesic agents are widely used but some antidepressants (ADs) showed analgesia also. Bupropion is using for smoke cessation but it can change morphine withdrawal signs such as pain. This study tested the acute systemic effect of bupropion on formalin induced pain behavior in rats.Methods: Wistar male healthy rats were divided into 7 groups (control, sham, and 5 treated groups with 10, 30, 90, 120, and 200 mg/kg of bupropion, i.p.). The bupropion injected 3 hours prior to formalin induced pain behavior. Formalin (50 μl, 2.5%) was injected subcutaneously in dorsal region of right hindpaw in all animals. Nociceptive signs were observed continuously on-line and off-line each minute. Common pain scoring was used for pain assessment. Results: The analysis of data by one-way ANOVA showed that bupropion can reduce pain scores in the second phase but not in first phase. Bupropion decreased the licking/biting duration significantly in first and second phase of formalin test. Conclusions: The results showed that bupropion has analgesic effects at systemic application. The change of second phase of the pain behavior was significant and it revealed that central mechanisms involve in bupropion analgesia. (Korean J Pain 2014; 27: 118-124)

Nonlinear regression models based on the normal mean–variance mixture of Birnbaum–Saunders distribution

Mehrdad Naderi,Alireza Arabpour,Tsung-I Lin,Ahad Jamalizadeh 한국통계학회 2017 Journal of the Korean Statistical Society Vol.46 No.3

This paper presents a new extension of nonlinear regression models constructed by assuming the normal mean–variance mixture of Birnbaum–Saunders distribution for the unobserved error terms. A computationally analytical EM-type algorithm is developed for computing maximum likelihood estimates. The observed information matrix is derived for obtaining the asymptotic standard errors of parameter estimates. The practical utility of the methodology is illustrated through both simulated and real data sets.