Callus distraction method를 이용한 하악골 신장술 : 계단골절단술식의 적용

김명진,윤필영,신동준,김수경,김종원,김규식 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.2

Since callus distraction technique was applied clinically for the correction of dentofacial deformity to the patients with hemifacial dysplasia by McCarthy in 1992, many surgeons have tried to apply this method to the maxillofacial region. But this technique has some drawbacks. One of the disadvantages of this technique is extensive scar formation in the facial area, which is a sequelae of extraoral approach for supraperiosteal dissection of the periosteum overlying the mandible. Recently, we have made an effort to perform this technique through intraoral approaches to prevent scar formation on the submandibular area and modified the design of the osteotomy, that is step osteotomy technique, to increase the raw bone surface on both osteotomized segments. The rationale for the application of this step osteotomy technique is to increase the amount of regeneracted bone and the length of distraction, to avoid damage of inferior alveolar neurovascular bundle, and to increase initial stability of the splitted segments. Step osteotomy procedure can be done with fine micro-osteotomy saw through subperiosteal tunneling. Extraoral pins should be inserted before making the osteotomy. Since 1974 we have applied this technique at 8 sites In 5 patients with mandibular deficiencies: 2 cases of hemifacial microsomia, 1 case of developmental facial asymmetry and 2 cases of mandibular bony defect. Mandibular elongation have been achieved from 12 to 20mm in length. 1 out of 8 site, we experienced non-union in the case of mandibular body defect. Some skeletal relapse and growth retardation phenomenon have been observed in some cases with the longest follow-up of 48 months.

Cathelin-related antimicrobial peptide (CRAMP)의 화학합성 및 구조- 항생물활성

하종명,이상현,하배진 신라대학교 자연과학연구소 1998 自然科學論文集 Vol.5 No.-

CRAMP, a cathelin-related antimicrobial peptide was identified from cDNA sequence derived from mouse bone marrow cells. In this study, in order to investigate the structure-antibiotic function relationships of CRAMP, the mature CRAMP was synthesized by solid phase method using Fmoc-chemistry. CRAMP showed more potent antimicrobial activity against gram-positive bacteria than gram-negative bacteria. Minimum inhibitory concentrations of CRAMP against Bacillus subtilis and Escherichia coli were 3.125-6.25μM and 50μM, respectively. CRAMP displayed a powerful antitumor activity against human small cell lung cancer cell lines (50% growth inhibitory concentration : 13 μM). However, CRAMP did not show hemolytic activity against human erythrocytes at peptide concentration of 50 μM. CD spectra analysis showed that CRAMP will form an amphipathic α-helical structure similar to other antimicrobial peptides such as cecropins, melittin and magainins.

Compositional Analyses of Electrodeposited II-VI Compound Semiconductor Thin Films

이명진,최홍진,전종호,명노승 건국대학교 자연과학연구소 1998 建國自然科學硏究誌 Vol.9 No.2

Cd+Se 혼합물의 열화학적 성질을 DSC를 이용하여 조사하였다. Cd과 Se분말을 이용하여 분석한 결과 Cd이 녹기 전 까진 CdSe의 형성이 관측되지 않았지만, Cd의 녹는 점 이상에서는 온도와 반응시간에 따라 상당한 양의 CdSe가 만들어지는 것을 알 수 있었다. 이상의 방법을 토대로 전기 화학적으로 합성한 CdSe박막의 조성을 분석하였다. 일정 전압에서 합성한 CdSe 박막을 DSC로 분석한 결과 Cd,Se 그리고 CdSe의 양을 각각 분석할 수 있었다. The thermochemistry of the condensed-phase Cd+Se=CdSe system was studied by differential scanning calorimetry(DSC). Formation of CdSe was not initiated until fusion of Cd reactant. However, increase of temperature or reaction time resulted in the formation of CdSe although there was no clear exothemic peak. Based on the thermochemistry of Cd+Se system, compositional analysis of electrodeposited CdSe thin films by the DSC was described. Potentiostatic deposition of CdSe thin films contained free Cd, free Se and CdSe depending on the deposition potential. Interesting features of Se thermochemistry were also described.

일부 농촌지역 청소년층의 성장발육과 영양상태에 관한 연구

김종진,윤태영,최중명,박순영,구도서,박양원 慶熙大學校 1987 論文集 Vol.16 No.-

In order to assess the physical growth and development, and nutritional status of primary, middle and high school students in the town of Samchoek, Kangwon province as rural area, physiques of 3,793 persons(Male; 1,884. Female; 1,909)were measured from May 1 to May 31 in 1986 and various physical and nutritional indices related to them were calculated.

음성의 묵음구간 검출을 통한 DTW의 성능개선에 관한 연구

김종국,조왕래,배명진 한국음성과학회 2003 음성과학 Vol.10 No.4

Speaker recognition is the technology that confirms the identification of speaker by using the characteristic of speech. Such technique is classified into speaker identification and speaker verification; The first method discriminates the speaker from the preregistered group and recognize the word, the second verifies the speaker who claims the identification. This method that extracts the information of speaker from the speech and confirms the individual identification becomes one of the most efficient technology as the service via telephone network is popularized. Some problems, however, must be solved for the real application as follows; The first thing is concerning that the safe method is necessary to reject the imposter because the recognition is not performed for the only preregistered customer. The second thing is about the fact that the characteristic of speech is changed as time goes by, So this fact causes the severe degradation of recognition rate and the inconvenience of users as the number of times to utter the text increases. The last thing is relating to the fact that the common characteristic among speakers causes the wrong recognition result. The silence parts being included the center of speech cause that identification rate is decreased. In this paper, to make improvement, We proposed identification rate can be improved by removing silence part before processing identification algorithm. The methods detecting speech area are zero crossing rate, energy of signal detect end point and starting point of the speech and process DTW algorithm by using two methods in this paper. As a result, the proposed method is obtained about 3% of improved recognition rate compare with the conventional methods.

일부 생산직 근로자의 소음과 사회심리적 요인이 혈압에 미치는 영향

박종구,강명근,차봉석,고상열,장세진,고상백 大韓産業醫學會 1997 대한직업환경의학회지 Vol.9 No.2

This study was conducted to assess the effects of noise exposure and psychosocial factor on blood pressure in manufacturing workers. The study subjects are 414 workers(243 males, 171 females) employed at the noisy department. The mean age of low exposed group(<85dB) was 34.65±9.53 years, and that of high exposed group(≥85dB) was 36.37±11.15 years. The difference in mean age was not significant. The mean and distribution of working duration, smoking status, drinking status were not significantly different between two groups. The mean systolic blood pressure of the low exposed group was 120.01±12.06 mmHg, and that of high exposed group was 126.27±13.84mmHg. The mean diastolic blood pressure of the low exposed and the high exposed group were 77.18±10.83 mmHg, and 83.46±11.22mmHg respectively. These differences of blood pressure were statistically significant(p<0.05). The workers in noisy department have significantly less work environmental satisfaction, higher job demand, and higher social support. The mean values of psychosocial distress were higher in the workers of the noisy department, but the difference was not statistically significant. This study was to speculate whether the work environmental satisfaction and social support modify the association between the noise exposure level and the blood pressure. The result showed that work environmental satisfaction could not modify the association between the blood pressure and the noise exposure. Social support at work did not modify the association. Furthermore, we evaluated the high job strain from a combination of ratio of the high job strain group for hypertension in diastolic blood pressure were statistically significant, but not in systolic blood pressure. Hierarchical multiple regression analysis was used to determine whither the independent variables contributed to explaining the blood pressure. After controlling for possible confounders, we found that the noise exposure level was a correlated of the diastolic blood pressure. But no association between the noise exposure level and the systolic blood pressure. No significant result was found for psychosocial factor.

비복신경이식을 이용한 긴 거리의 말초신경 결손부 수복

이종호,이세영,김명진,이은진,안강민,김성민,최원재,명훈,황순정,서병무,최진영,정필훈 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.2

The surgery of oral and maxillofacial area poses the risk of cranial nerve damage such as trigeminal nerve or facial nerve. Inferior alveolar nerve is prone to damage in the third molar extraction, implant installation, orthognathic surgery, open reduction and rigid fixation, and tumor ablation surgery. On the other hands,facial nerve is likely to be damaged or sacrificed with trauma or parotidectomy. In case of inferior alveolar nerve injury, the incidence is reported to be about 1.3%. The nerve function will almost recover in minimal damage, but it won't recover at last in total damage of a part of nerve unit. In latter cases, nerve regeneration in intended by allograft as nerve substitute or various route of merve condit. But the recovery with autograft is believed to be most relialbe mrthod in the rapair of long-span(longer than 15㎜)nerve defect. We have performed autologous sural nerve graft in the repair of nerve defect, which is caused by resection of benign or malignant tumor. Hereby we report the method of nerve harvesting, recovery of defected peripheral nerve and the complications of donor site with the discussion of sural nerve anatomy.

개입연구를 통한 근로자 경견완 장애의 개선효과

손명호,손석준,박종,최진수,김양옥 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.4

Objectives : In order to reveal the effectiveness of the intervention in the workplace on patients suffering from cervicobrachial disorder(CBD), we reexamined 96 workers out of 137 workers suffering from CBD on the assembly lines of an electric manufacturing factory by using questionnaires, physical exams and neurological exams. Methods : Analyses were made of the characteristics of the 96 workers of this company suffering from 1994 to 1996 with special concern for differences before and after the improvement of the working environment. After reexamination of the 96 patients the following results were obtained. Results : We observed an improvement in the 10 most common subjective symptoms of CBD. These symptoms included general fatigue, pain on neck and shoulders, dullness of the upper extremities, back pain and discomfort and a tingling sensation in the hands and wrists(p<0.05). The percentage of workers who complained muscle tenderness of neck and shoulder were reduced(p<0.05). the percentage of workers with abnormal Morley examination was reduced from 28.5% to 2.1%(p<0.01), and of workers with abnormal EMG finding went from 12.4% to 2.1%(p<0.01) and of grade 3 and grade 4 CBD was reduced from 42.3% and 18.3% respectively to 33.3% and 2.1%(p<0.01). Grade 3 and over laborers of CBD had higher scores in somatization, anxiety, depression, hostility, interpersonal sensitivity, phobic anxiety, obsessive-compulsive, neurasthenic, hypochondriacal than other sufferers in the SCL-90-R exam(p<0.01). Conclusions : in conclusion intervention had effectiveness on subjective symptoms of neck and shoulder and decreasing abnormal finding of muscle tenderness, neurological examination and EMG.

하악골 골절후의 골치유과정에 있어서 방사선학적 추적조사

최진영,김명호,허경희,서병무,이종호,정필훈,김명진 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.5

The results of radiographic study of healing of fractured mandible are often inconsistent with clinical evaluation of bone healing pattern of it. In addition, there is inconsistency between radiographic studies. We think if such inconsistency is resolved, clinical assessment combined with radiologic evidence can be used to guide to more accurate clinical management. The purpose of this study is to evaluate radiological healing pattern of mandible, and to apply its result to clinical use. Panoramic view was used to analyze the change of radiographic finding in 35 patients (27 male, 8 female, ranging 17 to 53 years old) treated for mandibular fracture at the department of oral & maxillofacial surgery, SNUH in the period 1991 to 1998, Patients are all treated by rigid internal fixation using monocortical miniplate. Within 9 weeks, no change is observed at fracture site. Osteogenic change is observed at various time interval (3 to 21 weeks). We have found radiographic change of healing is observed 4 to 6 weeks later to clinical healing, According to this result, we recommend radiographic follow-up at 4 week, 10 week, 10 month.

Goretex를 이용한 융비술

최진영,민철기,명훈,황순정,서병무,이종호,정필순,김명진 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.4

융비술시 실리콘 고무는 다루기 쉽고 조직 반응이 적어 현대 많이 돌출의 합병증이 생길 수 있다. 저자등은 이러한 실리콘의 단점을 보완할 수 있는 goretex를 사용하여 융비술을 시행하고 비첨에 대해서 자가연골을 이식하여 만족할 만한 결과를 얻었기에 goretex가 안면부 연조직의 증강을 위한 이식재료로 적합하다고 생각되어 문헌고찰과 함께 보고하는 바이다. Many different materials have been used to provide augmentation of the nasal dorsum. this include both autogenous and homogenous materials,as well as allografts. Silicone among the artificial materials has been most widely used. The silicone has some advantages and disadvantages. Goretex(expanded polytetra-fluoroethylene) which has widely used in vascular surgery and abdominal surgery can be used for facial soft tissue augmentation. The author presemts 2 cases of nasal augmentaion using goretex with literature review.