기계적 처리와 금속촉매 오존산화에 의한 슬러지 감량화

윤상현,장현섭,이명주,황선진 경희대학교 2005 環境硏究 論文集 Vol.14 No.-

This research investigated the effect of mechanical pretreatment and ozone/catalytic oxidation on the reduction of sewage sludge. The pretreatment process was carried out to enhance sludge solubilization. The degree of solubilization was evaluated based on the DR. TS 1∼4% sludge was treated by ball mil using glass beads of 1 mm in diameter with the 50% (v/v) zircon bead loading. TS 4% showed 4 times higher solubilization efficiency than that of untreated sludge. The combination of the mechanical pretreatment and ozone/catalytic oxidation(10 mg Mn/g TS) showed higher efficiency than ozone/catalytic oxidation. At the 40% solubilization efficiency of sludge achieved by using ball mill, combination treatment showed 3 times higher than control. Ozone/catalytic oxidation improved the solid reduction effectively in the lower pH, presumably due to a high production of OH radical.

녹차분말 첨가가 약과의 품질과 저장성에 미치는 영향

윤근영,김명애 한국식생활문화학회 2005 韓國食生活文化學會誌 Vol.20 No.1

The objective of this study was to clarify the effect of addition of green tea powder(0%, 2%, 4%, 6%, 8%) to Yackwa on quality and preservation. Addition of 4% green tea powder turned out to give positive effect on expansion. In test of physical characters, addition of green tea powder had a tendency to lower hardness, cohesiveness, springness and gumminess but to enhance brittleness. Considering the rancidity of oil within Yackwa, addition of green tea powder tended to show lower acid value and peroxide value than non-added treatment but its difference was slight. At the sensory test, surface color, bitterness and green tea flavor were strong but sweet and savory taste weak when green team powder was added(p〈0.05). Overall quality appeared to have improved to 5.55 points which is compared to non-addition when the powder was added 4%(p〈0.05). In conclusion, 4% addition of green tea powder would be the usefull method to enhance preference and quality of Yackwa.

녹차분말 첨가가 약과의 품질과 저장성에 미치는 영향(2)

윤근영,김명애 생활과학연구소 2005 생활과학연구 Vol.10 No.-

The objective of this study was to clarify the effect of addition of green tea powder(0%, 2%, 4%, 6%, 8%)each to Yackwa on quality and preservation. Addition of 4% green tea powder turned out to give positive effect on expansion. Addition of green tea powder to test physical character showed a tendency to lower hardness, cohesiveness, springness and gumminess but to enhance brittleness. For the sensory test, overall quality appeared to have improved or unchanged compared to control sample when the powder was added 2% and 4%.(p<0.05). In conclusion, 4% addition of green tea powder would be a usefull method to enhance preference and quality of Yackwa.

부영양화 방지를 위한 정석탈인법의 응용성 제고 연구

윤명희,김소연,왕창근 忠南大學校 環境問題硏究所 2002 環境硏究 Vol.20 No.-

The purpose of this study is to develop phosphorus removal technology by crystallization on various materials for prevention eutrophication. This study was based on precipitation mechanism and was performed to see phosphorus removal efficiency of activated carbon, anthracite, aluminium and wasted concrete etc. The results obtained from this study are following ; The granular activated carbon coated with dissolved clamshell showed good removal efficiency, 82% of phosphorus. For anthracite after coating, 49% of phosphorus was removed. Other materials such as aluminium and wasted concrete could remove 40% and 48% of phosphorus, respectively. Judging from the results from this research, this technology can be applied for prevention of eutrophication and algal bloom in the lakes.

흰 민들레 추출물의 항산화능 및 항균활성

박명수, 라만, 임우종, 김기윤, 우성만, 이선미, 사동민 忠北大學校 農業科學硏究所 2011 農業科學硏究 Vol.27 No.4

-본문참고-

새로운 백금착체인 tetrachloro [bis(2-chloroethyl)ethylenediamine-N,N']platinum(IV)과 cisplatin이 마우스의 면역반응에 미치는 영향

표명윤,유경미,최지선,오현정 숙명여자대학교 약학연구소 1993 약학논문집-숙명여자대학교 Vol.9 No.-

Effects of a new platinum complex, tetrachloro-[bis(2-chloroethyl) ethylenediamine-N,N']platinum(IV)[PtCl₄-2(CEen)] and cisplatin on the immune response were investigated. Male ICR mice were treated at the respective LD50(20% or 60% LD50) of cisplatin and PtCl₄-2(CEen). The results were as following : LD50 of PtCl₄-2(CEen) for male ICR mouse was 122.5mg/kg(i.p.) and higher than cisplatin(16.3mg/kg, i.p.). Body-, spleen-, thymus-, liver-weight, number of WBC and RBC were reduced dependently on the dose and day of administeration of cisplatin and PtCl₄-2(CEen). But these toxicities produced by PtC^-^CEen) appeared to be relatively less and to improve faster than by cisplatin. The titers of hemagglutinin and hemolysin to SRBC in mice received cisplatin and PtCl₄-2(CEen) were decreased significantly and independently on the day of antigen injection. Cisplatin and PtCl₄-2(CEen) stimulated significantly contact hypersensitivity to DNFB when administered prior to sensitization(DNFB), but suppressed slightly when administered after sensitization.

2- [4-cyanophenyl)amino)]-3-chIoro-1,4-naph thalened ione (NQ-Y15)가 마우스의 면역병리 및 체액성 면역에 미치는 영향

표명윤 숙명여자대학교 약학연구소 2002 약학논문집-숙명여자대학교 Vol.18 No.-

In order to investigate the effects of 2-[(4-cyanophenyl)amino]-3-chloro-l,4-naphthalenedione (NQ-Y15) on immune system in mice, we examined the immunopathological parameters and splenic IgM plaque forming cells (PFC) in this study. The immunopathological parameters (weights of body and organs, hematological parameters) were examined on day 1, 2,4 and 6 following single oral administration of NQ-Y15 (125, 250, 500 mg/kg) to female ICR mice. The weight of body was not changed. However, the weights of organs were slighty increased, and among hematological parameters WBC and platelet (PLT) were slightly changed in a dose- and test day-dependent manner when compared with control group. When NQ-Y15 was administered before immunization with SRBCantigen, PFC was significantly and dose-independently enhanced, but PFC was slightly decreased only at a high dose of NQ-Y15 when administered after antigenic challenge. These results indicate that the effects of NQ-Y15 on primary humoral immune response may be dependent on the timing of its administration relative to the initial antigenic challenge.

Cyclophosphamide에 의한 세포성 면역반응의 조정에 관한 연구

表明允 淑明女子大學校 1986 論文集 Vol.27 No.-

Varying combinations of cyclophosphamide (CY, single dose at day-6∼day +4) plus allo-transplantation antigen (allo-TA, lymphocytes from C3H mice at day 0) were injected into normal or presensitized Balb/c mice. The resulting T-effector cell reactivity was determined in vitro with mirocytotoxicity test and the mechanism responsible for the effect of CY on the cell-mediated immunity (CMI) was studied with one way-mixed lymphocyte culture (MLC). The results were as follows : (1) LD_50 of CY for female Balb/c mouse was 510mg/kg body weight (i.p.). (2) CY showed immunostimulative effect when administered prior to allo-TA, and immunosuppressive effect when administered after allo-TA on both of the primary and secondary CML.(3) Change of the dose of CY (20%, 60% LD_50) caused only quantitative variation in the immunomodulating effect. (4) The reduced MLC reactivity of normal lymphocytes was induced by CY and antigen-treated lymphocytes. This results support that CY activates the mitomycin C-nonsensitive T suppressor cell but not T Helper cell.

Toluene diisocyanate(TDI) 및 Diphenylmethane diisocyanate(MDI)의 變異原性과 細胞毒性과의 相關性 硏究

표명윤,양미희 숙명여자대학교 약학연구소 1995 약학논문집-숙명여자대학교 Vol.11 No.-

TDI(Toluene diisocyante) and MDI(Diphenylmethane diisocyanate) used as hardners in the production of polyurethane, showed following cytotoxicity and mutagenic activities. 1. Using TA98 without metabolic activation(S_9), TDI at the does, 78-625㎍/plate, completely inhibited TA98 growth. However TDI at the higher does than that, stimulated bacterial growth. With metabolic activation(+S_9), simillar tendency was observed but the magnitude of cytotooxicities of _S_9 was weaker than those of -S_9, Cytotoxicity pattern of MDI was similar to that of TDI, but its potency is higher than TDI's. 2. TDI and MDI appeared to be mutagenic to TA98 only after metabolic activation and this was more apparent when their cytotoxicities were diminished. Although results are not conclusive, they also showed similar tendency in the case of S_9 free condition. 3. TDI and MDI showed significant mutagenic action on TA100 only after the presence of S_9 mix, without any effect on TA100 growth. In concusion, considering the facts that TDI and MDI have strong cytotoxicites and there was increasing tendency in the mutagenic activities accompanied decrease of cytotoxicities, it could not be ruled out that TDI and MDI are not only secondary mutagens but also primary mutagens.

고등학교 생물 '생명의 연속성' 단원 분석 : 탐구 활동을 중심으로

김명란,김윤희,조은희 조선대학교 사범대학 부설 교과교육연구소 2000 敎科敎育硏究 Vol.3 No.1

Recent advances in biotechnology has centered around the field of genetics. Although the likely benefits of biotechnology is obvious, it is assuring that the potential risks has to be carefully weighed. It also rasied new social and ethical issues in everyday life experiences. Thus, biology education especially in the units on biotechnology and genetics should emphasize social implications of the technology. In this study, the "Continuity of Life" unit in high school biology Ⅱ curriculum was analyzed in the context of Science, Technology and society(STS). The unit, "Continuity of Life", describes basic genetic phenomena and evolution of life. five different high school biologyⅡ textbooks were chosen and inquirty content dimension, and the inquiry process dimension. Analyses of the inquiry content dimension showed that 40.6% of inquiry activities in the unit were devoted to the evolution part and those for cell division, reproduction and development, and Mendelian genetics were at most 8.7%, 13.0%, and 16.0%, respectively. In the inquiry process dimension. ´interpreting data and formulating generalization´ and ´observation and measuring´categories consist of 81.1%. The other categories, ´seeing a problem and seeking ways to solve it´and ´building, testing, and revising the theoretical model´were under represented. In the context dimension, the scientific context consists of 73.0% and the proportion of the other three categories, individual context, the social context, and the technical context was only 26.1% in total. In conclusion, the analysis of inquiry activities on the "Continuity of Life" unit in five textbooks composed based upon the Sixth Curriculum of High School Education failed to show intimate relationship between science and society and simply concentrated on description and explanation of scientific facts. Provided the fact that the Biology Ⅱ is used in the highchool class for students who want to be future natural science majors of who show special interests in natural science, it is important for students to understand the ethical and social issues that recent biotechnology rasied and to become scientifically literate and responsible persons.