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Background : Varicose vein is the most common venous disease of the lower extremities. The treatment of varicose vein is commonly performed for cosmetic improvement, although most patients are symptomatic as well. Sclerotherapy is a useful adjunct to large vein surgery as well as a highly effective primary treatment for telangiectasia and reticular vein. Objective : The purpose of this study was to elucidate the clinical characteristics of varicose vein of Korean and to evaluate the efficacy and the side effect of sclerotherapy. Methods : We reviewed 100 outpatients treated by sclerotherapy for varicose vein at department of dermatology of Pusan National University Hospital from January, 1999 to December, 2000. Results : The results obtained were summarized as follows; 1) The distribution of age was the first 5th decade(44%), followed by 4th decade and 6th decade. The median age was 47.6 years-old. 2) The duration of illness was less than 5 years in 34 patients(34%), and 6 to 10 years in 25Patients(25%). 3) Presumed etiologic factors were occupations requiring long period of standing in 43patients(43%), and pregnancy in 28 patients(28%). 4) The aims in treating varicose vein were cosmetic problem(88%), pain(47%) and fatigue(32%) 5) According to the CEAP classification, the most common type of varicose vein was C_lsEpAs(46%). 6) The frequency of injections were 2 times in 31 patients(31%), 3 times in 30 patients(30%), and one in 22 patients(22%). 7) Most of the patients were satisfied with the results and the clinical efficacy in varicose vein was more than moderate clearance in 64 patients(64%). Transient adverse effects were observed in a few patients. Conclusion : Sclerotherapy is a simple, safe, and cosmetically acceptable alternative treatment for varicose vein and can be easily performed in outpatient fields. (Korean J Dermatol 2003;41(2) : 158∼166)
Tidal characteristics have changed severely after constructions of seadike/seawalls near Mokpo Harbor. Tidal velocity of three layers, buoy paths and suspended sediment distributions are observed near there. The results can be useful database for calibrations of various numerical simulations for coastal and estuarine studies near Mokpo coastal zone.
As the current stage of the fashion begins to follow the styles of the past, the study on the past costume is getting more important, and as the methodology of the study accurately approached study through the rehabilitation of the past costume is more needed than the simple rearrangement of the historical documents. By this methodology, this study can be positioned as a recreation activity. The results of the study are as follows. 1) Style : The general silhouetts is the late crinoline style which is the period from 1860s to just before bustle. The dress is one-piece composed of fitted bodice, and skirt which the front is flat, side and back is triangular shape to the skirts. 2) Color and Material : the main color is pale stone and the sub-color is ivory and blue. The dress is made of a silk surface and cotton back and partly satin and velvet. 3) Pattern and sewing : the dress is together sewing comnined with lining and fabric. The skirt is gored skirt, the number of patterns is plenty because of the plenty of width of skirt. The double piping has various effect not only to decorate but also to conceal the seam, support the silhouette. 4) Detail : The general detail is double piping which are repeatedly used to decorate stand collar, bands of sleeve, froint bodice and gored panel seam of skirt. And the fringe and velvet ribbon are used to decorate the dress. 5) Structural characteristics : The double piping, velvet ribbon and twilled cotton are used to emphasize structural characteristics of crinoline style. And the waistband which is backed with a webbing band to reinforce it is also the structural characteristics. Synthetically, the 1886~7 day dress has the characteristics of transitional stage in which the chararcteristics of the costume of 1860s and the remnants of the characteristics of the previous costume style, and shows the characteristics of day dress well in terms of the style, color and fabrics, pattern and sewing, detail, and structural characteristics.
이 연구의 목적은 제 6차 교육과정에 의한 중학교 1학년 과학 교과서 분별 증류 실험의 문제점을 파악하고, 중학생들이 분별 증류 실험을 능률적으로 수행할 수 있는 실험 방법을 제시하고자 하는 것이다. 이를 위한 첫 번째 단계로서 현재 사용되고 있는 8종의 과학 교과서를 분별 증류 실험 장치와 액체 혼합물의 종류에 따라 6가지로 분류하였다. 두 번째 단계로서 액체 혼합물을 가열 방법에 따라 직접가열과 물 중탕 가열로 나누어 교과서 실험과정에 따라 같은 실험을 세 번 실시하였다. 세 번째 단계로서 실험 결과의 문제점을 해결하기 위한 대안 실험을 실시하였다. 대안 실험에서는 알코을 램프로 직접가열 하는 방법과 기름 중탕으로 가열하는 방법, 그리고 가열 맨틀을 사용하여 가열하는 방법을 사용하였다. 연구결과, 가지 달린 둥근 플라스크를 직접 가열하는 실험 결과가 가지 달린 시험관을 물 중탕으로 가열하는 실험 결과보다 이론적인 결과에 근접하였다. 그리고 가지 달린 둥근 플라스크를 직접 가열하는 실험에서 플라스크 윗 부분을 보온해 주는 실험이 보온하지 않은 실험보다 실험 결과가 더 나았다. 대안 실험에서는 액체 혼합물의 증류 온도 증가를 보면서 가열 맨틀의 가열 온도를 을려 준 실험의 결과가 이론적인 결과에 가장 가까웠다. 이러한 연구 결과로부터 가지 달린 시험관을 물 중탕으로 가열하는 분별 증류 실험 장치는 탐구실험 수업에 부적절한 것이므로 개선이 요구되며, 중학교 과학실 여건을 고려할 때, 액체 혼합물의 증류 온도 증가를 보면서 가열 맨틀의 가열 온도를 변화시키는 분별 증류 실험이 가장 능률적인 방법임을 알 수 있었다. The purpose of this study was to find out the problems on the fractional distillation experiments in the middle school science textbooks based on the 6th curriculum and to suggest an efficient experiment method for the middle school students. The first step was the classification of the experiments in 8 science textbooks according to heating apparatus and liquid mixtures. The second step was doing each experiment 3 times followed by the experimental process in the textbooks. The third step was developing the alternative experiments for solving the problems found in the second step. The heating method used in the alternative experiments were direct heating, oil bath, and heating mantle. The results of the second step showed that the direct heating experiment of branched round flask was more close to the theoretical prediction than the experiment of water bath heating of branched test tube. Also the direct heating experiment of thermally insulated branched round flask was better than the result of the experiment which was not insulated. The results of the third step showed that the experiment using heating mantle regulated heating power by observing the temperature of distillate gave the closest result to the theoretical prediction. From the above results, it is concluded that the experiment using branched test-tube with water bath heating is not adequate for the fractional distillation and an alternative experiment using insulated branched round flask with heating mantle regulated heating power during experiment is recommended.
Pyomyositis is an acute bacterial infection of skeletal muscle usually due to Staphylococcus aureus. Salmonella species represent an uncommon causative agent of pyomyositis which has been reported in patients with various underlying illnesses. We experienced a case of pyomyositis caused by Salmonella enteritica serovar Enteritidis in a 45-year-old diabetic man who was admitted with a two-week history of progressive pain of left knee and hip joint. Computed tomography revealed a 4.0 cm-sized ovoid abscess in the left iliacus muscle, which underwent incision and drainage. Culture obtained at operation revealed S. enteritidis. The patient was successfully managed with drainage and ciprofloxacin.
Background : The aging of skin is influenced by genetic, environmental, and hormonal factors. Estrogens are the "missing" player in the skin of postmenopausal women. In postmenopausal women, loss of collagen was related to decreased estrogen level. Phytoestrogens, i.e. isoflavone, are plant compounds with estrogen-like biologic activities. Objective : The effects of 18β-estradiol, and isoflavones on production of type Ⅰ collagen in the fibroblast of postmenopausal woman, keloid and Detroit cell line were examined. Methods : Type Ⅰ collagen was measured with procollagen type Ⅰ C-peptide EIA KIT. Results : 18β-estradiol and isoflavone enhanced the production of type Ⅰ collagen in cultured fibroblast of postmenopausal woman and keloid. But isoflavone inhibited the production of collagen in cultured fibroblast of Detroit cell. Conclusion : 18β-estradiol and isoflavone can prevent and improve the cutaneous alterations caused by loss of collagen of postmenopausal women. (Korean J Dermatol 2003;41(8) : 1041~1048)
Changbudodamhwan(CBH) is used in female infertility caused by ovulation disorder. An attempt was made to evaluate the influences of CBH on the serum concentrations of FSH, LH, estradiol(E_(2)) and progesterone, the histological and optical changes of ovary, ovary weight of rats. The results of the study were as follows : 1. Blood FSH level increased experimental group as compared with control group, which showed no efficacy. 2. Blood LH level increased in experimental group as compared with control group, which showed no efficacy. 3. Blood E_(2) level increased in experimental group as compared with control group, which showed no efficacy. 4. Blood progesterone level increased in experimental group as compared with control group, which showed no efficacy. 5. In optically observations of ovary, weight of ovary increased in experimental group as compared with control group, which showed no efficacy. 6. In histological observations of ovary, ovulation increased in experimental group as compared control group, which showed efficacy. According to these results, CBH influence on the ovulation and ovary of rats.
Background: Many dermatologists usually prescribe antibiotics postoperatively to prevent the wound infection, but there are no definite guidelines for the use of prophylactic antibiotics in skin biopsy. Objective: The purpose of this study is to evaluate the efficacy of prophylactic antibiotice after skin biopsy. Methods: We performed the prospective study of 200 patients in skin biopsy. We excluded patients who have a risk failure, chronic hepatic failure, anemia, internal malignancy, untreated diabetes, immune suppression, taken antibiotic within 1 week, hypersensitivity to antibiotics and infected wound. They were classified randomly into two troups, each 100 patients with or without antibiotic prophylaxis. All patient received the wound dressing. All biopsy wounds were evaluated in a blinded fashion at the time of suture removal and scored according to a standardized assessment based on erythema, edema and discharge. Results: Of the 100 patients who received the wound dressing and the prophylactic antibiotics postoperatively, no one had surgical wound infection. Of the 100 patients who received only the wound dressing, one patient had surgical wound infection. Conclusion: The infection rates were not significantly differnet between two groups. Therefore prophylactic antibiotics after skin biopsy may not be necessary to prevent wound infection in healthy patients. (Korean J Dermatol 2004;42(1):16~22)
Background and Objectives : Epidermal growth factor receptor (EGFR), a 170-kDa transmembrane glycoprotein, appears to mediate epidermal growth factor (EGF) activity. Transforming growth factor-α and EGF produce their biological effects in numerous systems by stimulating the EGFR In this study, we examine the postnatal development of EGFR immunoreactivity in the different regions of the thalamus of the rat Materials and Methods : The present study is based on 28 postnatal cases of rat thalamus ranging from the day of birth, postnatal day 0 (P0) to 30 days (P3, P5, P10, P15, P20, P30), and these cases were compared with adult rat thalamus. Cryostat sections were processed free-floating with monoclonal antibody by immunohistochemistry Results : EGFR immunoreactivity in the thalamus of the rat showed very different patterns according to postnatal ages and thalamic areas. EGFR-immunoreactive cells appeared in the first two postnatal weeks, except the ventral posterior thalamic nuclei. In the early postnatal days, EGFR-immunoreactive cells appeared thalamic midline structures, increased progressively in the first two postnatal weeks, and followed mediolateral gradient. The mature patterns of EGFR-immunoreactive cells were achieved at P20 Conclusion : These data indicate that the maturation of EGFR-immunoreactive cells requires a relatively prolonged period of time to achieve an adult configuration. Many growth factors probably play protective or neurotrophic roles at EGFR-immunoreactive neurons of thalamus both young and adult rats In addition to difference in time of appearance in thalamic nuclei and developing pattern with mediolateral gradient suggest that EGFR-immunoreactivities are correlated with the appearance of the related functional.