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Electron Interference in a Quantum Ring with a Tunable Magnetic Field Shield
Minky Seo,Hwanchul Jung,Yunchul Chung 한국진공학회(ASCT) 2021 Applied Science and Convergence Technology Vol.30 No.2
A quantum ring device that can turn on and off the external magnetic field on the ring is developed. The device is to study the effect of the interaction between electrons and external magnetic fields on Aharonov-Bohm interference. The switching is realized by employing a superconducting shield gate and turning on and off the superconductivity on the gate with applied current or magnetic field. The electron interference due to Aharonov-Bohm effect is observed regardless of the presence of the external magnetic field on the electron path of the ring. The result is consistent with the fact that effects of potentials on charged particles exists even in the region where all the field vanish hence no direct interaction between electron and magnetic field is allowed.
Electronic-temperature estimation of Joule-heated graphene via Raman investigations
Seo Minky,Kim Do-Hoon,Lee Jae-Hyun,Son Seok-Kyun 한국물리학회 2021 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.78 No.2
Temperature-dependent Raman scattering provides valuable information on electron–phonon coupling and phonon anharmonicity of graphene. In this study, we show an enhancement of Joule heating in graphene by confining the current flow in a narrow channel. In addition, we performed a detailed analysis of the anharmonic effect in the hBN/monolayer graphene/hBN heterostructure based on the behaviour of the full-width at half maximum of the G mode with increasing electric power: a non-monotonic trend, leading to the key of approximation of the electronic temperature in graphene. We believe our results could offer a convenient analysis tool to study electron–phonon coupling and anharmonic phonon-decay processes in a high-temperature regime.
Rampogu, Shailima,Son, Minky,Park, Chanin,Kim, Hyong-Ha,Suh, Jung-Keun,Lee, Keun Woo Hindawi 2017 BioMed research international Vol.2017 No.-
<P>Breast cancer is one of the leading causes of death noticed in women across the world. Of late the most successful treatments rendered are the use of aromatase inhibitors (AIs). In the current study, a two-way approach for the identification of novel leads has been adapted. 81 chemical compounds were assessed to understand their potentiality against aromatase along with the four known drugs. Docking was performed employing the CDOCKER protocol available on the Discovery Studio (DS v4.5). Exemestane has displayed a higher dock score among the known drug candidates and is labeled as reference. Out of 81 ligands 14 have exhibited higher dock scores than the reference. In the second approach, these 14 compounds were utilized for the generation of the pharmacophore. The validated four-featured pharmacophore was then allowed to screen Chembridge database and the potential Hits were obtained after subjecting them to Lipinski's rule of five and the ADMET properties. Subsequently, the acquired 3,050 Hits were escalated to molecular docking utilizing GOLD v5.0. Finally, the obtained Hits were consequently represented to be ideal lead candidates that were escalated to the MD simulations and binding free energy calculations. Additionally, the gene-disease association was performed to delineate the associated disease caused by CYP19A1.</P>
Kumar, Raj,Son, Minky,Bavi, Rohit,Lee, Yuno,Park, Chanin,Arulalapperumal, Venkatesh,Cao, Guang Ping,Kim, Hyong-ha,Suh, Jung-keun,Kim, Yong-seong,Kwon, Yong Jung,Lee, Keun Woo Springer Science and Business Media LLC 2015 Acta pharmacologica Sinica. Vol.36 No.8
<P>Recent evidence suggests that aldo-keto reductase family 1 B10 (AKR1B10) may be a potential diagnostic or prognostic marker of human tumors, and that AKR1B10 inhibitors offer a promising choice for treatment of many types of human cancers. The aim of this study was to identify novel chemical scaffolds of AKR1B10 inhibitors using in silico approaches.</P>
Thangapandian, Sundarapandian,John, Shalini,Son, Minky,Arulalapperumal, Venkatesh,Lee, Keun Woo Future Science 2013 Future medicinal chemistry Vol.5 No.1
<P>Human LTA4H catalyzes the conversion of LTA4 to LTB4 and plays a key role in innate immune responses. Inhibition of this enzyme can be a valid method in the treatment of inflammatory response exhibited through LTB4.</P>