Serial values for hematologic and biochemical analysis after myocardial infarction in rats

( Mi Jin Lee ),( Hyun Jin Tae ),( Ying Hua Li ),( Do Hyeon Yu ),( In Ae Han ),( Seok Won Lee ),( Dong Choon Ahn ),( In Shik Kim ),( Jin Ho Park ) 한국가축위생학회 2008 韓國家畜衛生學會誌 Vol.31 No.2

To diagnose acute myocardial infarction(MI), many cardiac markers have been used in hematologic and biochemical analysis, and many studies have been published for hema-tologic and biochemical analysis associated with human acute MI. However, after occurrence of acute MI, the serial investigation for values in hematologic and bioche-mical analysis including chronic MI has rarely been performed. To observe the change of the serial values in hematologic and biochemical analysis, we induced artificial MI. The left main descending artery(LMDA) of the left coronary artery was ligated during the progression(day 1, 3, 5, 7, 14 and 30) of MI. Total 66 Sprague-Dawley rats were divided into the sham group(n=24, thoracotomy without LMDA ligation) and the experimental(MI) group(n=42, with LMDA ligation). And all individual in each group was sacrified at day 1, 3, 5, 7, 14 and 30 for the hematologic and biochemical analysis. In comparison of hematologic analysis between the sham and MI groups, the mean values of red blood cell(RBCs), hemoglobin and hematocrit(HCT) showed a steady increase. In biochemical analysis, the mean values of glucose, choles-terol, total creatine kinase(CK) and isoenzyme MB, and lactate dehydrogenase(LDH) were increased in all MI groups compared with the sham groups. The results of this study suggest that early hematologic and biochemical mean values occurred after acute MI are similar to those of human acute MI. In conclusion, we could observe the alterations and serial values in hematologic and biochemical analysis to the extent of chronic status after acute MI.

Serial values for hematologic and biochemical analysis after myocardial infarction in rats

Lee, Mi-Jin,Tae, Hyun-Jin,Li, Ying-Hua,Yu, Do-Hyeon,Han, In-Ae,Lee, Seok-Won,Ahn, Dong-Choon,Kim, In-Shik,Park, Jin-Ho The Korean Society of Veterinary Service 2008 韓國家畜衛生學會誌 Vol.31 No.2

To diagnose acute myocardial infarction (MI), many cardiac markers have been used in hematologic and biochemical analysis, and many studies have been published for hematologic and biochemical analysis associated with human acute MI. However, after occurrence of acute MI, the serial investigation for values in hematologic and biochemical analysis including chronic MI has rarely been performed. To observe the change of the serial values in hematologic and biochemical analysis, we induced artificial MI. The left main descending artery (LMDA) of the left coronary artery was ligated during the progression (day 1, 3, 5, 7, 14 and 30) of MI. Total 66 Sprague-Dawley rats were divided into the sham group (n=24, thoracotomy without LMDA ligation) and the experimental (MI) group (n=42, with LMDA ligation). And all individual in each group was sacrified at day 1, 3, 5, 7, 14 and 30 for the hematologic and biochemical analysis. In comparison of hematologic analysis between the sham and MI groups, the mean values of red blood cell (RBCs), hemoglobin and hematocrit (HCT) showed a steady increase. In biochemical analysis, the mean values of glucose, cholesterol, total creatine kinase (CK) and isoenzyme MB, and lactate dehydrogenase (LDH) were increased in all MI groups compared with the sham groups. The results of this study suggest that early hematologic and biochemical mean values occurred after acute MI are similar to those of human acute MI. In conclusion, we could observe the alterations and serial values in hematologic and biochemical analysis to the extent of chronic status after acute MI.

Alginate 배양내에서 Transglutaminase가 연골막세포에 미치는 영향

박정선,공차배,김충현,안현정,정미현,성상철,김희중,조현철,이상훈,이명철 대한정형외과연구학회 2003 대한정형외과연구학회지 Vol.6 No.2

논쟁의 수사학 : 『라오콘 Laokoon』논쟁을 중심으로

안미현 한국독일어문학회 2003 독일어문학 Vol.22 No.-

Die Literaturdebatte ist ein Feld, in dem nicht nur einzelne literarische Probleme, sondern auch asthetische bzw. geistesgeschichtliche Ansatze zusammentreffen und demzufolge ein neuer Diskurs entsteht. Sie ist aber auch ein Raum, wo man alle rhetorischen Stilmittel erprobt und sich dieser bedient, um Argumentationen am effektivsten entfalten und dadurch das Publikum am besten uberzeugen zu konnen. Laokoon-Gruppe, ein Werk rhodischer Bildhauer aus dem 1. Jh. v. Chr., war ein Gegenstand der europaweiten Kunstdebatte. Diese seit der Antike viel diskutierte Plastik wurde in Deutschland durch Wickelmann wieder auf den Mittelpunkt der asthetischen Debatte gestellt, als er in seinen Gedanken uber die Nachahmung der griechischen Werke in der Malerei und Bildhauerkunst zu einem reprasentativen Beispiel erklarte, in dem das griechische Kunstideal der sogenannten "edlen Einfalt und stillen Große" vollkommen verkorpert sei. Daran anschließend versuchte aber Lessing, in seinem Laokoon oder uber die Grenze der Poesie und Malerei Winckelmanns Thesen zu widerlegen. Wahrend Winckelmann die neuere Kunst des Barocks, die damals besonders in Dresden erblumt war, aufgrund ihrer Ubertriebenheit, Unnaturlichkeit und Prunksucht verurteilte, schlug er vor, statt dieser die griechischen Kunstwerke nachzuahmen. Diese These Winckelmanns lehnte Lessing aber aufgrund der ‘zweiten Nachahmung’ ab, in der die Schonheit als hochstes Krieterium wirke, aber die individuelle Ausdruckskraft bzw. Originalitat der inventio weniger gefragt wurde. Lessings Kritik griff zugleich die herkommliche These des ‘ut pictura poesis’ an, bei der antike Dichter wie Simonides und Horatius die Verschiedenheiten der beiden Kunstgattungen Malerei und Dichtung, nicht berucksichtigt hatten. Lessing versuchte mit der Begrundung die klare Grenze zwischen der beiden zu ziehen, indem er argumentiert, dass man in ihnen wesentlich voneinander unterschiedene Kunstmittel verwende, die eine naturliche Zeichen, die andere willkurliche Zeichen. Im Bezug auf den anderen Streitspunkt geht es um die dispositio, namlich das Arragement der einzelnen Teile in der Poesie und Malerei. Winckelmann hatte behauptet, dass Laokoon die großten Schmerzen empfindend, nicht schreie, sondern nur seufze, was seiner Ansicht nach die Große seiner Seele zum Ausdruck bringen soll. Dagegen meinte Lessing, der Grund fur die Tatsache, dass Laokoons Mund nicht weit aufgerissen ist, liege eher darin, dass der geoffnete Mund das gesamte Gesicht Laokoons nicht nur verzerre, und sondern auch einen haßlichen Eindruck nachhaltig auf das Publikum mache. In einem weiteren Punkt geht es um die Allegorie: Winckelmann hatte der Allegorie große Bedeutung beigemessen, mit der der Kunstler dem Bild "die epische Große" verleihen konne. Lessing dagegen meinte, die Allegorie in der Bildhauerkunst bzw. in der Malerei sei nur ein Stilmittel, den abstrakten Begriff zu personifizieren, ein Stilmittel, das jedoch dem ursprunglichen Sinn nicht entspricht und eine Diskrepanz zwischen Inhalt und Gestalt erzeugt. In der Poesie sei sie dagegen ein unnotiges, unwesentliches Schmuckelement. Neben der inhaltlichen Analyse der Laokoon-Debatte wurden in dieser Studie die rhetorischen Strategien der Streitschrift untersucht, wie z.B. dedicatio, argumentatio, appellatio etc., die bei den beiden Autoren in unterschiedlicher Weise auftreten. Ein Hauptergebnis der Studie ist, dass in dieser Laokoon-Debatte eine neue Argumentationsmethode verwendet wird. Statt der einseitigen Lobrede oder der blinden Verleumdung, die in der fruheren Zeit haufig zu beobachten war, tritt nun die objektive, logische Beweisfuhrung in Vordergrund. die bei Lessing glanzend zum Tage tritt. Bei den beiden Autoren ist auch der Leser-Begriff von vornherein anders konzipiert. Winckelmann hatte erwahlte elitare Leser vor Augen, die von Geburt an den Kunstsinn besitzen. Lessing forderte aber den Leser zur aktiven Zusammenarbeit auf und wollte ihn zum idealen Leser erziehen, indem er ihn bald als Richter, bald als Zeuge hervorruft.

연골외막세포가 포함된 alginate beads를 이용한 토끼에서의 골연골결손 치료

안현정,김은미,정미현,조현철,이인범,성상철,이명철 대한정형외과연구학회 2003 대한정형외과연구학회지 Vol.6 No.2

양 하지의 근력저하를 주소로 응급실로 내원한 원발성 알도스테로증 1예

안력,김원,조규종,홍정석,이미우,장성은,오세현,임경수 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

A primary central nervous system lymphoma(PCNSL) is defined as a lymphoma limited to the cranial-spinal axis without systemic involvement. PCNSLs were formerly very rare, only 0.5∼ 1.2% of all intracranial neoplasms, and were usually associated with acquired immuno-deficiency syndrome(AIDS) and other immune-compromised states. Recently, there has been a clear rise in the incidence of this disease among normal individuals. We describe a 77-year-old female with hyponatremia who presented with a confused mental state. Computed tomography(CT) of the brain demonstrated a suprasellar mass with enhancement. We evaluated the basic hormonal studies and the magnetic resonance imaging(MRI). A ventricular biopsy was done, and the result was a diffuse, large, B-cell-type malignant lymphoma. She presented panhypopituitarism and partial central diabetes insipidus. She received chemotheraphy and was discharged in an improved condition. We report a case of panhypopituitarism due to PCNSL and give a review of the literature.

초등 영재학생과 일반학생의 진로인식, 과학 선호도 및 과학자의 정형화된 이미지 비교

안미정,유미현 韓國英才學會 2012 영재교육연구 Vol.22 No.3

본 연구의 목적은 초등학교 영재학급 학생과 일반학급 학생들의 진로인식과 과학 선호도 및 과학자의 정형화된 이미지를 비교하는 것이다. 본 연구를 위해 초등학교 6학년 영재학생 52명, 일반학생 80명이 연구에 참여하였다. 본 연구의 결과는 다음과 같다. 첫째, 영재학생과 일반학생의 진로인식을 비교한 결과, 영재학생들의 진로인식이 더 높게 나왔으며, 두 집단 간의 유의미한 차이가 나타났다. 이를 통해 전반적으로 일반학생에 비해서 영재학생의 진로인식이 높다는 것을 알 수 있다. 둘째, 영재학생과 일반학급 학생의 과학 선호도는 영재학생이 유의미하게 높은 결과가 나왔다. 하위영역별로 자세히 보면 6개의 모든 하위영역에서 영재학생이 일반학생보다 유의미하게 높았으며, 성별에 따른 비교에서도 영재학생에서만 유의미한 차이가 있었다. 또한 집단과 성별의 차이 간 상호작용 효과는 일반학생에 비하여 영재학생이 과학 학습의 흥미와 학습 지속 실행의지가 높게 나타났다. 셋째, 영재학생과 일반학생의 정형화된 과학자의 이미지 검사를 실시한 결과, 영재학생에 비해 일반학생이 느끼는 과학자의 이미지에서 더 많은 정형화된 모습을 볼 수 있었다. 넷째, 영재학생의 진로인식과 과학 선호도, 진로인식과 과학자의 정형화된 이미지의 상관관계를 살펴본 결과 각각의 변인들 간에 유의미한 상관관계가 나타났다. 다중회귀분석을 통해 진로인식이 과학 선호도에 유의미하게 영향을 준다는 결과를 얻었다. The purpose of this study was to investigate the career awareness, the preference for science and stereotypic image of the scientist between the gifted students and non-gifted students in elementary school. For this study, 52 gifted students and 80 non-gifted students were participated. The results were as follows: First, the career awareness of gifted students was significantly higher than that of non-gifted students. Second, the preference for science of gifted students was significantly higher in all sub-domains than non-gifted students. There was a significant interaction effect between group and gender in the scientific interest and the intention of solving problems. Third, analyzing stereotypic image test for scientist between the gifted students and non-gifted students, it proved that non-gifted students had more stereotypic image comparing with the gifted students. Forth, carrying out the correlation analysis on the career awareness and the preference for science, the career awareness and the stereotypic image of the scientist, it proved that there were significant correlations with each other. It revealed that the career awareness affected the preference for science significantly through multiple regression analysis.

파라캇에 의한 대뇌 피질 손상 : 증례 보고

안미영,신동익,이형석,백신혜,이성현,이상수 충북대학교 의과대학 충북대학교 의학연구소 2010 忠北醫大學術誌 Vol.20 No.1

Paraquat is widely used as a universal herbicide. Paraquat induces brain damage in case of fatal poisoning. It is well documented that paraquat exposure is associated with Parkinson's disease. However, many reports suggest paraquat is not selective for the dopaminergic nigro-strial system. Preferably, there are reports that cortical neurons were found to be more sensitive to paraquat. A39-year-old woman committed suicide by drinking 20 ml of a 20% solution of Paraquat. After 5 days, she had a convulsive seizure and lost consciousness. Brain MRI showed diffuse cerebral cortical edema of bilateral frontal and temporal lobes. She died 2 days after progressive pulmonary fibrosis. Here, we report a patient with paraquat induced cortical lesion. 파라캇은 세계적으로 널리 쓰이는 제초제이다. 파라캇은 중독되었을 경우 뇌손상을 일으키기도 한다. 파라캇과 파킨슨병과의 관련성은 비교적 잘 알려져 있다. 하지만, 파라캇이 도파민 줄무늬흑체 계통(dopaminergic nifro-striatal system)에 선택적이지 않다는 많은 보고들이 있다. 오히려, 대뇌피질이 파라캇 중독에 더욱 민감하다는 일부 보고들도 있다. 39세 여자환자가 자살할 목적으로 20% 농도의 파라캇 20 ml를 마시고 본원에 내원하였다. 환자는 입원 5일째 갑자기 전신 발작 증상과 함께 의식 저하 소견을 보였다. 다음날 시행한 뇌자기공명영상 촬영상 양쪽 측두엽과 전두엽에 대칭성 세포 도겅부종 소견을 보이고 있었다. 그녀는 2일 후 폐섬유화증에 의한 호흡부전으로 사망하였다. 저자들은 파라캇 중독 환자에서 대뇌 피질 손상을 확인한 1예를 경험하였기에 보고하는 바이다.

규범에 순응하는 번역·저항하는 번역 : 인식론적 토대와 사례 분석

안미현 이화여자대학교 이화인문과학원 2014 탈경계인문학 Vol.7 No.2

Norms of translation include various rules and customs that translators must necessarily acquire. Translators must learn these norms if they wish their products to be recognized and circulated in a certain society. Such products contain the preferred value and knowledge system of a certain period, such as the structure of emotion, among other things. In this network of norms inhere political, cultural, and verbal ideologies. Norms don’t operate separately, but build a network, even while they connect with or contradict each other. When translators depend excessively on dominant norms, their translations have the effect of ultimately excluding exotic factors and strengthening their own culture and language-system. We have examined such an example in Wilamowitz-Moellendorff ’s translations of ancient Greek texts: He replaces the Greek mythologies and gods by the Christianity of his time and place, and in this way reveals the national or imperial ideology of his era. Even though most translators tend to follow the ruling norms, a few translators resist these norms. We have seen such resistance in Höolderlin’s translations of Sophocles, for Höolderlin mediates new images of the Greek gods, in contrast to the images presented by other writers of his time. This art of translation transforms the fixed images of foreign culture through resistance to the ruling norms.

품종별 부추 추출물의 항산화성 및 항균성

안명수,김현정,서미숙 한국식생활문화학회 2005 韓國食生活文化學會誌 Vol.20 No.2

The antioxidative and antimicrobial activities were carried on the leeks (Allium tuberosun R.) ethanol extracts in order to find out new food functional components. Three species of leeks used in this study were Chinese leek(long type, LL), general leek(medium type, LM), and medicinal leek (short type, LS). Total amounts of polyphenol compounds in LS was shown as the highest (436.60㎎%) value. All of ethanol extracts of these leeks were shown to be had good electron donating ability(EDA) and nitrite scavenging activity. Specially, the ethanol extract of LS(LSEx) had the highest EDA 30.47% and nitrite scavenging activity 77.24% and the lowest was LMEx. The antioxidative activities of these ethanol extracts on the corn germ oil were measured by peroxide values(POV) and conjugated diene values (CDV) storaging for 30 days at 60±2℃. The antioxidative activities of these extracts by POV and CDV were determined as following order as LSEx> LLEx> LMEx. The antioxidative activities of all extracts were presented as high tendency by increasing adding amounts (0.02%〉0.05%〉0.1%). When the antioxidative activities were compared with BHT and a-tocopherol, the degree of the antioxidative activities of these extracts were certified as lower than BHT and higher than a-tocopherol. And also LSEx, LMEx, and LLEx had antimicrobial effects on the several micro organisms, especially the effect on the Pseudomonas aeruginasa was remarkable. While LMEx had shown inhibit effect on most of micro organism used in this study.