A Compaction Functionality Testing For Tableting Excipients and Introduction to a Compaction Data Bank

(Metin Celik),(Esay Okutgen) 한국약제학회 1993 PROCEEDINGS OF THE FIP POST-SATELLITE SYMPOSIUM `9 Vol.- No.-

Finite element analysis of RC walls with different geometries under impact loading

Metin Husem,Suleyman I. Cosgun,Hasan Sesli 사단법인 한국계산역학회 2018 Computers and Concrete, An International Journal Vol.21 No.5

Today, buildings are exposed to the effects such as explosion and impact loads. Usually, explosion and impact loads that act on the buildings such as nuclear power plants, airports, defense industry and military facilities, can occur occasionally on the normal buildings because of some reasons like drop weight impacts, natural gas system explosions, and terrorist attacks. Therefore, it has become important to examine the behavior of reinforced concrete (RC) structures under impact loading. Development of computational mechanics has facilitated the modeling of such load conditions. In this study, three kinds of RC walls that have different geometric forms (square, ellipse, and circle) and used in guardhouses with same usage area were modeled with Abaqus finite element software. The three configurations were subjected to the same impact energy to determine the geometric form that gives the best behavior under the impact loading. As a result of the analyses, the transverse impact forces and failure modes of RC walls under impact loading were obtained. Circular formed (CF) reinforced concrete wall which has same impact resistance in each direction had more advantages. Nonetheless, in the case of the impact loading occurring in the major axis direction of the ellipse (EF-1), the elliptical formed reinforced concrete wall has higher impact resistance.

The Relationship between Ghrelin and Copeptin Levels, and Anxiety and Depression Levels in Suicide Attempts

Metin Atescelik,Mustafa Yilmaz,Sevda Korkmaz,Mehmet Cagri Goktekin,Mehtap Gurger,NevinIlhan 대한정신약물학회 2017 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.15 No.3

Objective: It was aimed to detect acylated ghrelin (AG), unacylated ghrelin (UG) and copeptin levels in patients with suicide attempts and to determine if these biomarkers are risk factors for suicide attempts. Methods: Serum copeptin, AG and GU levels were screened in 128 patients who were admitted to emergency department with suicide attempts and 59 healthy controls. Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI) were applied simultaneously, and the data were compared statistically. Results: AG, UG and copeptin levels were higher in the patient group compared with the healthy control group. BAI scores of patients were found to be positively correlated with BDI scores. While there was a significant difference (p=0.0064) between psychiatric and non-psychiatric patients with suicide attempts in terms of BAI scores, there were no differences in BDI scores and levels of biomarkers. We found significantly increased BDI and BAI scores and increased levels of AG, UG and copeptin in psychiatric and non-psychiatric patients compared with healthy individuals. The specificities yielded by receiver operating characteristic curve analysis in patients with suicide attempts were as follows: 91.53% for AG, 72.88% for UG and 94.92% for copeptin. Conclusion: Serum levels of AG, UG and copeptin increase with increasing anxiety and depression in patients with suicide attempts. Increased levels of AG, UG and copeptin could be considered a risk factor for suicide attempts.

Diagonal bracing of steel frames with multi-cable arrangements

Metin Husem,Serhat Demir,Hong G. Park,Suleyman I. Cosgun 국제구조공학회 2016 Structural Engineering and Mechanics, An Int'l Jou Vol.59 No.6

A large number of structure in the world were build with poor seismic details, with or without any lateral load resisting system like concentrically braced frames and steel plate shear walls. These structures can reveal deteriorating hysteretic behaviors with stiffness and strength degradation. Therefore, seismic retrofitting of such structures for drift control has vital importance. In this study a retrofit methodology has been developed, which involves diagonal bracing of steel frames with different cable arrangements. In the experimental and numerical program 5 different lateral load resisting system were tested and results compared with each other. The results indicated that multi-cable arrangements suggested in this study showed stable ductile behavior without any sudden decrease in strength. Due to the usage of more than one diagonal cable, fracture of any cable did not significantly affect the overall strength and deformation capacity of the system. In cable braced systems damages concentrated in the boundary zones of the cables and beams. That is why boundary zone must have enough stiffness and strength to resist tension field action of cables.

From Romantic Historiography to Populist Folklorism:

Metin Turan Institute for Eurasian Turkic Studies Dongduk Wome 2018 The Journal of Eurasian Turkic Stidies Vol.1 No.-

Folklore studies in Turkey date back to the beginning of 20 th century, though folklore studies in the West originated almost a hundred years earlier, during the 19 th century. At this time, theoretical studies on folklore reached a significant level. The folkloric discipline remains a nascent one in Turkey, which has diversified the academic formations of those interested in the field. Initially folkloric research and interest was popularized by sociologist Ziya Gökalp, philosopher Rıza Tevfik, and historian Mehmet Fuar Köprülü and it also aroused interest of a huge mass of curious people with the popularity it evoked culturally. In particular, Community Centers that were founded in 1932 became the focal point for compiling oral and folk-culture products. Yaşar Kemal, a hugely important novelist who is cultivated in Turkish literature throughout the 20 th century, also made his mark on folkloric studies through his collation Ağıtlar which was published by Adana Community Center he joined when he started writing. Ultimately, Kemal became famous for the novels he wrote as an epic narrator of world literature. His phraseology, which was the subject of his novels, was based on his own knowledge of folklore. Kemal also told epics and sung ballads under the nickname “Kör Aşık”. Key words: Folklore, epic novel, epic, Turkish literature, Yaşar Kemal.

Inflammatory biomarkers may predict response to phosphodiesterase type 5 inhibitor treatment in patients with erectile dysfunction

Metin Kilic,Anil Erkan,Salim Zengin,Gokce Dundar,Caglar Boyaci 대한비뇨의학회 2023 Investigative and Clinical Urology Vol.64 No.4

Purpose: In this study, we aimed to evaluate the clinical utility of the neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), lymphocyte/monocyte ratio (LMR), and monocyte/high-density lipoprotein cholesterol ratio (MHR) in predicting response to a phosphodiesterase type 5 inhibitor (PDE5i) when used as the first-line medical treatment of erectile dysfunction (ED). Materials and Methods: This study prospectively included 185 patients who were diagnosed with ED and started PDE5i treatment. After PDE5i treatment, 107 (57.8%) patients with an International Index of Erectile Function-5 (IIEF-5) score below 22 were assigned to Group 1, and 78 (42.2%) patients with an IIEF-5 score of 22 or above were assigned to Group 2. The outcome measures of the study were demographic characteristics and inflammation markers between the groups. Results: The mean IIEF-5 change after PDE5i treatment was 6.1±4.2 points in Group 1 and 11.5±3.2 points in Group 2 (p=0.001). The mean age was 54.6±9.2 years in Group 1 and 47.8±10.3 years in Group 2 (p<0.001), and the median fasting blood glucose values of Groups 1 and 2 were 105 (36) mg/dL and 97 (23) mg/dL, respectively (p=0.010). The LMR and MHR values were 2.39±0.23 and 13.8±7, respectively, for Group 1, and 2.03±0.22 and 17±6.6, respectively, for Group 2 (p=0.044 and p=0.002, respectively). On multivariable analysis, younger age and increased MHR were independent predictors of benefit from PDE5i treatment. Conclusions: This study showed that only MHR as an inflammatory biomarker was an independent predictor for response to PDE5i in the treatment of ED. Also, several factors were predictive of treatment failure.

Zygoma-gear appliance for intraoral upper molar distalization

Metin Nur,Mehmet Bayram,Alper Pampu 대한치과교정학회 2010 대한치과교정학회지 Vol.40 No.3

본 증례보고에서는 골격성 II급 관계를 보이는 16세 여자환자에서 zygomatic-anchorage plates (Zygoma-gear Appliance,ZGA)를 이용하여 상악 구치를 후방 이동시킨 구내 장치를 소개하고자 한다. 이 장치는 양측성 zygomatic anchorage plates, inner-bow와 강한 힘을 내는 구강 내 고무줄로 구성되어 있다. 3개월 내에 상악 구치의 후방 이동이 이루어졌으며, 측모 두부 방사선 사진 분석 결과, 상악 구치는 4 mm 후방 이동, 4.5˚ 후방 경사되었다. 본 연구 결과 ZGA 장치를 이용해 고정원 소실 없이 단기간에 상악 구치의 후방 이동이 효과적으로 이루어졌음이 확인되었으며, 이를 통해 구치의 후방 견인이 요하는 증례에서 구외 장치 대신 사용될수 있을 것으로 판단된다. The aim of this report is to present an intraoral upper molar distalization system supported with zygomatic anchorage plates (Zygoma-gear Appliance, ZGA). This system was used for a 16-year-old female patient with a Class II molar relationship requiring molar distalization. The system consisted of bilateral zygomatic anchorage plates, an inner-bow and heavy intraoral elastics. Distalization of the upper molars was achieved in 3 months and the treatment results were evaluated from lateral cephalometric radiographs. According to the results of the cephalometric analysis, the maxillary first molars showed a distalization of 4 mm, associated with a distal axial inclination of 4.5˚. The results of this study show that an effective upper molar distalization without anchorage loss can be achieved in a short time using the ZGA. We suggest that this new system may be used in cases requiring molar distalization in place of extraoral appliances.

Behavior of reinforced concrete plates under impact loading: different support conditions and sizes

Metin Husem,Suleyman I. Cosgun 사단법인 한국계산역학회 2016 Computers and Concrete, An International Journal Vol.18 No.3

In this study, effects of impact loads on reinforced concrete (RC) plates are examined analytically. During examination of RC plates, they were exposed to impact loading with two different support conditions in three different sizes. RC plates in different support conditions were analyzed with Concrete Damage Plasticity Model (CDP) and reinforcing steel was modeled with Classical Metal Plasticity Model (CMP) by ABAQUS finite element software. After the analysis it is found that impact loads, displacements, energy absorption capacities and damage patterns are changed due to support conditions and plate sizes. Results that are obtained from RC plate experiments in literature under impact loads are found to be similar with the results of numerical analysis with CDP material models.

Effects of conventional and self-etching adhesive systems on bond strength of orthodontic attachments bonded to erupted and unerupted teeth

Metin Nur,Tancan Uysal,Cemal Yesilyurt,Mehmet Bayram 대한치과교정학회 2010 대한치과교정학회지 Vol.40 No.4

Objective: The aim of this study was to evaluate and compare the shear bond strength (SBS) and failure-mode of orthodontic buttons bonded to erupted and unerupted teeth with conventional and self-etching adhesive systems. Methods: Eighty-four erupted and 84 unerupted, human third-molar teeth were used. For both groups, the buccal surfaces of each tooth were assigned one of the following type of adhesive systems (n = 12). A, Conventional systems: 1, Transbond XT (3M Unitek, Monrovia, CA, USA); 2, Prime & Bond NT (Dentsply/Caulk, Milford, USA); 3, Single Bond (3M ESPE, Minnesota, USA); and B, Self-etching adhesives; 4, Clearfil SE Bond (Kuraray, Okayama, Japan); 5, Transbond Plus (3M Unitek, Monrovia, CA, USA); 6, Clearfil S3 (Kuraray, Tokyo, Japan); 7, G Bond (GC, Tokyo, Japan). The SBSs of the attachments and the adhesive remnant index (ARI) scores were recorded. Data were analyzed with analysis of variance (ANOVA), independent-sample t-test and chi-square tests. Results: When the SBSs of erupted and unerupted teeth were compared, only the Clearfil-SE Bond and G-Bond were significantly different. Bond strengths of all adhesive systems were higher in unerupted teeth than erupted teeth, except the Single-Bond system. Conclusions: When using conventional adhesives, bonding to erupted and unerupted teeth may not be significantly different. However, clinicians need to take into consideration the types of self-etching systems before usage. 이번 연구의 목적은 맹출 또는 미맹출된 치아에 교정용 버튼을 부착 후 자가부식 접착제(self-etching adhesive)의 사용 유무에 대한 전단결합강도(shear bond strength)와 탈락모드를 비교하고자 함이다. 각각 84개의 맹출 또는 미맹출된 제3대구치를 사용하였다. 각각 치아의 협측면을 다음의 부착시스템 그룹으로 할당하였다. A, 기존방식: 1, Transbond XT (3M Unitek); 2, Prime & Bond NT (Dentsply/Caulk); 3, Single Bond (3M ESPE); B, 자가부식 접착제; 4, Clearfil SE Bond (Kuraray); 5, Transbond Plus (3M Unitek); 6, Clearfil S3 (Kuraray); 7, G Bond (GC). 부착물의 전단강도와 접착제 잔류지수를 측정하였으며 결과값은 ANOVA와 independent t-test 및 chi-square 검증을 통해 분석되었다. 맹출 또는 미맹출된 치아의 전단결합강도를 비교하였을 때 Clearfil SE와 G Bond에서 유의한 차이가 관찰되었다. Single Bond를 제외한 모든 접착시스템에서 맹출보다는 미맹출 치아면에서 높은 접착강도가 관찰되었다. 기존 접착제를 사용하는 경우 맹출 또는 미맹출 치아에 대한 접착강도에는 차이가 없을 수 있다. 그러나 임상의사는 사용 전에 self-etching system의 종류를 고려할 필요가 있다.

Design of interlocking masonry units and mechanical properties of masonry assemblages

Metin Husem,Fatma Birinci Kayaalp 사단법인 한국계산역학회 2019 Computers and Concrete, An International Journal Vol.23 No.2

This paper describes the design of a new interlocking masonry system, the production of designed interlocking units and mechanical properties of interlocked masonry assemblages with mortar. In this proposed system, units have horizontal and vertical locks to integrate the units to the wall and have a channel to enable the use of horizontal reinforcements in the wall. Using these units, unfilled, filled or reinforced walls can be constructed with or without mortar. In the production of the interlocking units, it was decided to use foamed concrete. 12 trial productions have been carried out at different mix proportions to obtain the optimum concrete mix. At the end of the mentioned productions, the units were produced with foam concrete which is selected as the most suitable in terms of compressive strength and specific gravity. Then, axial compression, diagonal tension and bed joint shear tests were carried out to determine the mechanical properties of the interlocked masonry assemblages with mortar. Results from the tests showed that interlocks designed to strengthen the system against shear stresses by creating discontinuity throughout the joints have been successful to achieve their aim. Obtained data will enable structural analysis of walls to be constructed with these new units.