Benign hepatocellular nodules of healthy liver: focal nodular hyperplasia and hepatocellular adenoma

( Massimo Roncalli ),( Amedeo Sciarra ),( Luca Di Tommaso ) 대한간학회 2016 Clinical and Molecular Hepatology(대한간학회지) Vol.22 No.2

Owing to the progress of imaging techniques, benign hepatocellular nodules are increasingly discovered in the clinical practice. This group of lesions mostly arises in the context of a putatively normal healthy liver and includes either pseudotumoral and tumoral nodules. Focal nodular hyperplasia and hepatocellular adenoma are prototypical examples of these two categories of nodules. In this review we aim to report the main pathological criteria of differential diagnosis between focal nodular hyperplasia and hepatocellular adenoma, which mainly rests upon morphological and phenotypical features. We also emphasize that for a correct diagnosis the clinical context such as sex, age, assumption of oral contraceptives, associated metabolic or vascular disturbances is of paramount importance. While focal nodular hyperplasia is a single entity epidemiologically more frequent than adenoma, the latter is representative of a more heterogeneous group which has been recently and extensively characterized from a clinical, morphological, phenotypical and molecular profile. The use of the liver biopsy in addition to imaging and the clinical context are important diagnostic tools of these lesions. In this review we will survey their systematic pathobiology and propose a diagnostic algorithm helpful to increase the diagnostic accuracy of not dedicated liver pathologists. The differential diagnosis between so-called typical and atypical adenoma and well differentiated hepatocellular carcinoma will also be discussed. (Clin Mol Hepatol 2016;22:199-211)

A Multidisciplinary Approach for Model Predictive Control Education: A Lego Mindstorms NXT-based Framework

Massimo Canale,Simone Casale-Brunet 제어·로봇·시스템학회 2014 International Journal of Control, Automation, and Vol.12 No.5

This work introduces an educational framework based on the Lego Mindstorms NXT robotic platform used to outline both the theoretical and practical aspects of the Model Predictive Control (MPC) theory. The framework has been developed in the widely used MatLab/Simulink environment. A two-wheeled inverted pendulum is considered as hands-on experimental scenario. For such a system, starting from its mathematical modeling, an established design methodology is presented aiming to outline step-by-step the predictive controller implementation on a low power architecture. This methodology stress the design of a non-linear MPC controller on a low power embedded system, pruning the designer to deal with hard real time constraints without impacting the overall design requirements. The effectiveness of this multidisciplinary approach is shown through this presentation and demonstrated with experimental results.

Manque de présence et explosion de sensorialité dans la communication contemporaine : une sémiotique des « gastromanies » à partir d’À rebours.

Massimo Leone 한국영상문화학회 2016 영상문화 Vol.0 No.28

Retrospective evaluation of circulating thyroid hormones in critically ill dogs with systemic inflammatory response syndrome

Massimo Giunti,Roberta Troia,Mara Battilani,Luciana Giardino,Francesco Dondi,Giulia Andreani,Federico Fracassi 대한수의학회 2017 Journal of Veterinary Science Vol.18 No.4

Critical illness can be associated with transient alterations in circulating thyroid hormone concentrations, indicating the presence of non-thyroidal illness (NTI). NTI is well described in humans, but there are few reports on its occurrence and prognostic significance in dogs. This retrospective study assessed the occurrence of NTI in a population of dogs with systemic inflammatory response syndrome (SIRS) and investigated its association with disease severity (APPLEfast scores). A total of 41 SIRS dogs were included and were divided by SIRS origin (non-septic SIRS, n = 10; septic SIRS, n = 41) and final outcome (survivors, n = 37; non-survivors, n = 4). Healthy, age-matched dogs (n = 15) were included as controls. Serum thyroid hormone levels including total T3, free T3, total T4, and reverse T3 were measured upon admission. Compared to controls, there were significant changes in serum thyroid hormone concentrations in SIRS dogs, suggesting the presence of NTI. Septic SIRS dogs had higher APPLEfast scores and lower serum thyroid hormones concentrations than those in non-septic SIRS and control dogs. In conclusion, NTI was frequent in dogs with SIRS and may be associated with the presence of sepsis or high illness severity.

Sémiotique de la vacuité

Massimo Leone 고려대학교 응용문화연구소 2015 에피스테메 Vol.0 No.13

The article first interrogates words’ ability of undoing things, taking asexamples the Islamic verbal formula for divorcing a wife and atheistrituals for religious disaffiliation. Having pointed out differences andsimilarities between words that do things and words that undo them, thearticle then tackles the question whether images can do things in the sameway as words do them in the frame of speech acts theory. Finally, it dealswith the issue of whether images too, like words, can be used not only todo things, but also to undo them. The case study of images used toritually undo imagination, like yantras or hesychastic icons, is analyzed.

Safety Knowledge and Changing Behavior in Agricultural Workers: an Assessment Model Applied in Central Italy

Massimo Cecchini,Roberto Bedini,Davide Mosetti,Sonia Marino,Serenella Stasi 한국산업안전보건공단 산업안전보건연구원 2018 Safety and health at work Vol.9 No.2

Background: In recent years, the interest in health and safety in the workplace has increased. Agriculture is one of the human work activities with the highest risk indexes. Studies on risk perception of agricultural workers are often referred to as specific risk factors (especially pesticides), but the risk perception plays an important role in preventing every kind of accident and occupational disease. Methods: The aim of this research is to test a new method for understanding the relation between risk perception among farmers and the main risk factors to which they are exposed. A secondary aim is to investigate the influence of training in risk perception in agriculture. The data collection was realized using a questionnaire designed to investigate the risk perception; the questionnaire was given to a sample of 119 agricultural workers in central Italy. Through the use of the “principal components analysis” it was possible to highlight and verify the latent dimensions underlying the collected data in comparison with scales of attitudes. Results: Results show that the highest percentage of strong negative attitude is among the people who have worked for more years, while farmers who have worked for fewer years have a marked positive attitude. Conclusion: The analysis of the questionnaires through the synthetic index method (Rizzi index) showed that agricultural workers involved, in particular the elderly workers, have a negative attitude towards safety; workers are hostile to safety measures if they have not attended special training courses.

SG_02 (stool)

( Massimo Aurelio Cappella ) 한국기초조형학회 2019 한국기초조형학회 작품집 Vol.2019 No.1

Seismic Isolation of Lead-Cooled Reactors: the European Project SILER

MASSIMO FORNI,ALESSANDRO POGGIANTI,RICCARDO SCIPINOTTI,ALBERTO DUSI,ELENA MANZONI 한국원자력학회 2014 Nuclear Engineering and Technology Vol.46 No.5

SILER (Seismic-Initiated event risk mitigation in LEad-cooled Reactors) is a Collaborative Project, partially fundedby the European Commission in the 7th Framework Programme, aimed at studying the risk associated to seismic-initiatedevents in Generation IV Heavy Liquid Metal reactors, and developing adequate protection measures. The project started inOctober 2011, and will run for a duration of three years. The attention of SILER is focused on the evaluation of the effectsof earthquakes, with particular regards to beyond-design seismic events, and to the identification of mitigation strategies,acting both on structures and components design. Special efforts are devoted to the development of seismic isolationdevices and related interface components. Two reference designs, at the state of development available at the beginning of the project and coming from the 6thFramework Programme, have been considered: ELSY (European Lead Fast Reactor) for the Lead Fast Reactors (LFR),and MYRRHA (Multi-purpose hYbrid Research Reactor for High-tech Applications) for the Accelerator-Driven Systems(ADS). This paper describes the main activities and results obtained so far, paying particular attention to the development ofseismic isolators, and the interface components which must be installed between the isolated reactor building and the nonisolatedparts of the plant, such as the pipe expansion joints and the joint-cover of the seismic gap.

Huysmans gastronome: Une sémiotique des gastromanies contemporaines à partir d’À rebours

Massimo Leono 고려대학교 응용문화연구소 2019 에피스테메 Vol.0 No.22

L’article se veut une réflexion sur la sémiotique des cultures gastronomiques contemporaines, visant en particulier leurs obsessions alimentaires, qu’on appelle de plus en plus des « gastromanies ». Véritable symptômes du malaise existentiel contemporain, elles se caractérisent pour un déplacement continuel du seuil de l’identité, de l’appartenance, et du plaisir. L’article en retrace la généalogie culturelle et les tendances communicationnelles à partir de celui qui fut peut-être le premier à les détecter et à les transmettre sous forme narrative, à savoir Joris-Karl Huysmans dans À rebours.

Torino printanière – Méditations pour une sémiotique culturelle des images

Massimo Leone 고려대학교 응용문화연구소 2012 에피스테메 Vol.0 No.8

The paper tries to explore the potentialities of a cultural semiotics of images through both a comparison with other semiotic approaches and through the example of a specific analysis: a cultural semiotic study of De Chirico’s painting Torino printanière. The traditional Greimasian approach to the semiotic analysis of images, it is argued, fails in explaining how their meaning depends on the cultural contexts of their production and reception. Likewise, the traditional Echian approach underestimates the fact that ideally cooperative spectators are nowadays more an exception that the norm: as a consequence of the globalization and digitalization of images, more and more people lack an adequate “encyclopedia” to interpret images they are confronted with. The paper therefore claims that a cultural semiotics of images is urgently needed, and contends that the school of Moscow/Tartu can provide many suggestions about how to conceive it. According to Jurij M. Lotman’s theory, indeed, images must be interpreted in relation to their semiosphere, a hypothesis ― formulated through the meta-discourse of semiotics ― about how a culture produces and manages meaning both inside such culture and in relationships with what such culture considers as external to it. However, the paper points out, in Lotman’s theory the semiosphere is not only a repository of texts, but also a mechanism that produces them. As a consequence, semioticians can both study a semiosphere in order to understand the meaning of an image, and analyze an image in order to understand the meaning of a semiosphere. The paper concludes that only the synergic approach between micro-semiotic and macro-semiotic analysis ― including the methods of post-greimasian semiotics ― is able to formulate solid hypotheses not only on what images meant at the moment of their production, but also what they mean when they are received in a completely different semiosphere, by people whose visual culture is sometimes radically different from that of the image’s original context.