Cytogenetic assessment of <i>Lilium longiflorum × L. hansonii</i> revealed by genomic in situ hybridization (GISH)

Mazharul, I.M.,Reshma, Y.,Jung, J.M.,Mohammad, D.D.,Lim, K.B. International Society for Horticultural Science 2019 Acta Horticulturae Vol.1237 No.-

<P> Martagon (<I>Lilium hansonii;</I> MM) and <I>Longiflorum</I> (LL) are two major groups under the family <I>Liliaceae</I>, used for modern breeding to introduce new inter-genomic lily cultivars. Interspecific F<SUB>1</SUB> hybrids (LM) introduced through cut-style method between two diploid <I>Lilium longiflorum (2n=2x=24)</I> and <I>Lilium hansonii (2n=2x=24)</I> were evaluated cytogenetically by genomic in situ hybridization (GISH) technique. However, GISH analysis of F<SUB>1</SUB> interspecific (LM) hybrids showed equal chromosomal contribution from both female <I>Lilium longiflorum</I> (LL) and male <I>Lilium hansonii</I> (MM). Each of the parent contributed 12 chromosomes except three crosses i.e., two of <I>L. longiflorum</I> 'White Tower' × <I>L. hansonii;</I> (2x-1) and one of <I>L. longiflorum</I> 'Bright Tower' × <I>L. hansonii;</I> (2x-1). Among 11 inter-genomic crosses, 3 crosses failed (False hybrid) and 8 crosses (True hybrids) showed different ploidy level i.e., 2n=2x=24, 2n=2x-1=23 and 2n=2x-1=23 respectively. Recombinant chromosome usually not found in F<SUB>1</SUB> interspecific lily hybrids. Most often, genomic recombination occurred in the cross between two genetically different parents. Chromosome pairing and crossing over normally occurred during meiosis in backcross progenies. However, in this study, genome analysis (GISH) of F<SUB>1</SUB> hybrids (<I>L. longiflorum</I> 'White Tower' × <I>L. hansonii</I>) showed four recombinant sites including two M/L and two L/M recombinant chromosomes that denotes high genetic relationship between <I>L. longiflorum</I> and <I>L. hansonii.</I> </P>

Hydrogen production by auto-thermal reforming of ethanol over nickel catalyst supported on metal oxide-stabilized zirconia

Youn, M.H.,Seo, J.G.,Song, I.K. Pergamon Press ; Elsevier Science Ltd 2010 International journal of hydrogen energy Vol.35 No.8

Metal oxide-stabilized mesoporous zirconia supports (M-ZrO<SUB>2</SUB> with different metal oxide stabilizer (M = Zr, Y, La, Ca, and Mg) were prepared by a templating sol-gel method. 20 wt% Ni catalysts supported on M-ZrO<SUB>2</SUB>(M = Zr, Y, La, Ca, and Mg) were then prepared by an incipient wetness impregnation method for use in hydrogen production by auto-thermal reforming of ethanol. The effect of metal oxide stabilizer (M = Zr, Y, La, Ca, and Mg) on the catalytic performance of supported nickel catalysts was investigated. Ni/M-ZrO<SUB>2</SUB>(M = Y, La, Ca, and Mg) catalysts exhibited a higher catalytic performance than Ni/Zr-ZrO<SUB>2</SUB> because surface oxygen vacancy of M-ZrO<SUB>2</SUB>(M = Y, La, Ca, and Mg) and reducibility of Ni/M-ZrO<SUB>2</SUB>(M = Y, La, Ca, and Mg) were enhanced by the addition of lower valent metal cation. Hydrogen yield over Ni/M-ZrO<SUB>2</SUB>(M = Zr, Y, La, Ca, and Mg) catalyst was monotonically increased with increasing both surface oxygen vacancy of M-ZrO<SUB>2</SUB>support and reducibility of Ni/M-ZrO<SUB>2</SUB>catalyst. Among the catalysts tested, Ni catalyst supported on yttria-stabilized mesoporous zirconia (Ni/Y-ZrO<SUB>2</SUB> showed the best catalytic performance.

Frustrated minority spins in GeNi₂O₄

Matsuda, M.,Chung, J.-H.,Park, S.,Sato, T. J.,Matsuno, K.,Aruga Katori, H.,Takagi, H.,Kakurai, K.,Kamazawa, K.,Tsunoda, Y.,Kagomiya, I.,Henley, C. L.,Lee, S.-H. Editions de Physique 2008 Europhysics letters Vol.82 No.3

<P>Recently, two consecutive phase transitions were observed, upon cooling, in an antiferromagnetic spinel GeNi<SUB>2</SUB>O<SUB>4</SUB> at <I>T</I><SUB><I>N</I>1</SUB>=12.1 K and <I>T</I><SUB><I>N</I>2</SUB>=11.4 K, respectively (Crawford M. K. <I>et al</I>., <I>Phys. Rev. B</I>, <B>68</B> (2003) 220408(R)). Using unpolarized and polarized elastic neutron scattering we show that the two transitions are due to the existence of frustrated minority spins in this compound. Upon cooling, at <I>T</I><SUB><I>N</I>1</SUB> the spins on the ⟨111⟩ kagome planes order ferromagnetically in the plane and antiferromagnetically between the planes (phase I), leaving the spins on the ⟨111⟩ triangular planes that separate the kagome planes frustrated and disordered. At the lower <I>T</I><SUB><I>N</I>2</SUB>, the triangular spins also order in the ⟨111⟩ plane (phase II). We also present a scenario involving exchange interactions that qualitatively explains the origin of the two purely magnetic phase transitions.</P>

방사성 동위원소옥소(131I)에 의한 갑상선질환의 임상적 연구

이정상,이문호,고창순,노흥규,구인서,서환조,이경자,이홍규 대한핵의학회 1970 핵의학 분자영상 Vol.4 No.2

서울대학교 의과대학 내과학교실 및 방사성 동위원소 진료실에서 1960년 5월부터 1969년 10월까지 진료한 2,658명의 각종 갑상선 질환 환자에 대하여 131I에 의한 각종 갑상선 기능 검사 및 기능 항진증 환자에 대한 131I의 치료 성적을 종합 검토하여 아래와 같은 결론을 얻었다. 1) 2,658명의 갑상선 질환 환자중 독성 미만성 선종이 929명(34.9%)으로 가장 많고 비중독성 미만성 선종 및 비중독성 결절성 선종이 각각 762명(28.7%), 699명(26.3%)이며 기능저하가 210명(7.9%), 독성 결절성 선종이 58명(2.2%)였다. 2) 갑상선 질환의 성별 발생 빈도는 남자 300명(11.4%), 여자 2,358명(88.6%)로서 그 비는 1:8였다. 3) 연령별 발생 빈도는 20∼49세에서 전체의 79.1%인 2,102명이며 기능 항진증의 경우는 79.0%에 달하였다. 4) 각종 갑상선 기능 검사중 131I 섭취율, 131I 혈청내 방사능 BMR치등에 대한 고찰을 하는 한편 기능항진 및 저하증때 나타내는 각종 자학증세를 관찰하였다. 5) 갑상선 기능 항진증 환자 867명에 대하여 131I 치료를 하고 그 중 579명에서 47.8%의 초회 치료율을 확인하였다. 6) 131I 투여 후의 합병증인 기능 저하증의 발생 빈도는 초회 투여에서 6.75%였다. 7) 갑상선의 $quot; A summary of the clinical data of the (131)^I-thyroid function tests and the therapeutic results of 1(31I)^ among the 2,658 patients of various thyroid diseases treated over the past 10 years from May 1960 to Oct. 1969 at the Radioisotope Clinci and Laboratory, SNUH were presented and discussed. 1) The patients examined consisted of 929 cases (34.9%) of diffuse toxic goiter, 762 cases (28.7%) of diffuse nontoxic goiter, 699 cases (26.3%) of nodular nontoxic goiter, 58 cases (2.2%) of nodular toxic goiter and 210 cases (7.9%) of hypothyroidism. 2) There were 300 (11.4%) male and 2358 (88.6%) female, showing a ratio of 1:8. 3) The majority of patients (79.1%) were in the 3rd-5th decade of their lives. 4) The normal ranges, diagnostic values of (131)^I uptake test, 48 hrs serum activity, BMR and main subjective symptoms of various thyroid diseases were discussed. 5) In the 579 patients among 867 cases with hyperthyroidism treated with (131)^I, 47.8% were confirmed to be cured completely after single therapeutic doses. 6) The complications of 131I therapy were discussed and myxedema had developed in 6.75% of our patients. 7) The results of (131)^I thyroid function tests were analysed among the 160 cases of thyroid diseases which were confirmed the diagnosis with histopathological measures.

돼지의 선발에 있어서 능력검정 방법에 따른 육종가 및 유전적 개량량의 변화

조규호,김시동,김명직,이일주,전광주 한국동물자원과학회 2001 한국축산학회지 Vol.43 No.6

본 연구에서는 이유시체중(㎏), 90㎏ 도달일령을 대상형질로 하여 폐쇄돈군에서 이유시 체중을 기초로 5가지의 선발방법에 따라 선발된 선발축의 산육 능력을 검정하여 검정이 완료된 개체들에 대해 유전능력 평가를 실시한후 검정대상 선발두수의 크기에 따른 유전적 개량량을 비교하여 이상적인 검정방법을 찾고자 실시하였다. 시뮬레이션 결과 90㎏ 도달일령에 대한 육종가 추정치의 변화는 Method Ⅴ그룹에서 -36.2일의 단축효과를 보였으며 세대당 유전적 개량량 또한 Method Ⅴ그룹에서 -7.5일로 가장 높은 개량을 보였다. 따라서 개량적인 측면에 있어서는 전수검정을 실시하는 것이 가장 좋을 것으로 사료되지만 농장의 검정능력이나 전수검정을 실시할 때 드는 초과비용에 대한 경제적인 분석은 더 연구되어져야 될 것으로 사료된다. This study was carried out to find the ideal testing method by comparing predicted breeding values, and genetic gain by the size of testing group. Tested traits were weaning weight and days to 90㎏. Five methods for selecting testing group were adopted: Method Ⅰ (MⅠ ; 30% selected based on litter weight at weaning for female, and 30% selected based on individual weight at weaning for mail), Method Ⅱ (MⅡ ; 30% selected based on individual weight at weaning for female and male, respectively), Method Ⅲ (MⅢ ; 50% selected based on individual weight at weaning for female and male, respectively), Method Ⅳ (MⅣ ; 70% selected based on individual weight at weaning for female and male, respectively), Method Ⅴ (MⅤ ; all piglets were tested). Genetic ability was evaluated by multiple trait animal model using MTDFREML package. Based on the predicted breeding values for days to 90㎏, the next generation was selected up to 5th generation. The above procedure were repeated and simulated by 4 times. The results obtained in the present study are summarized as follows; Phenotypic mean and predicted breeding values mean of days to 90㎏ was 114.3, -27.8, 113.7, -27.0, 107.5, -32.6, 105.7, -34.4, 103.7 and -36.2 days for MⅠ, MⅡ, MⅢ, MⅣ and MⅤ, respectively. Phenotypic and predicted breeding values variance of days to 90㎏ was 20.9, 4.1, 19.0, 3.4, 15.3, 1.8, 13.8, 1.7, 13.3 and 1.2 days for MⅠ, MⅡ, MⅢ, MⅣ and MⅤ, respectively. Genetic gain of days to 90㎏ was -6.2, -6.0, -7.1, -7.3 and -7.5 days for MⅠ, MⅡ, MⅢ, MⅣ and MⅤ, respectively. In all case, Method Ⅴ group, all piglets be tested, is the most efficient for improving the target economic traits.

Minimum permanents on two faces of the polytope of doubly stochastic matrices

Pula, K.,Song, S.Z.,Wanless, I.M. North Holland [etc.] 2011 Linear algebra and its applications Vol.434 No.1

We consider the minimum permanents and minimising matrices on the faces of the polytope of doubly stochastic matrices whose nonzero entries coincide with those of, respectively,U<SUB>m,n</SUB>=I<SUB>n</SUB>J<SUB>n,m</SUB>J<SUB>m,n</SUB>0<SUB>m</SUB>andV<SUB>m,n</SUB>=I<SUB>n</SUB>J<SUB>n,m</SUB>J<SUB>m,n</SUB>J<SUB>m,m</SUB>. Here J<SUB>r,s</SUB> denotes the rxs matrix all of whose entries are 1, I<SUB>n</SUB> is the identity matrix of order n and 0<SUB>m</SUB> is the mxm zero matrix. We conjecture that V<SUB>m,n</SUB> is cohesive but not barycentric for 1<n<m+m and that it is not cohesive for n≥m+m. We prove that it is cohesive for 1<n<m+m and not cohesive for n≥2m and confirm the conjecture computationally for n<2m≤200. We also show that U<SUB>m,n</SUB> is barycentric.

Analysis of the relationship between the kinetic energy and intensity of rainfall in Daejeon, Korea

Lim, Y.S.,Kim, J.K.,Kim, J.W.,Park, B.I.,Kim, M.S. Pergamon Press 2015 QUATERNARY INTERNATIONAL Vol.384 No.-

The kinetic energy and momentum of rainfall are widely used as erosivity indicators for estimating soil detachment (erosion) induced by the impact of raindrops. Because direct measurements of the force or kinetic energy of rainfall on ground surfaces are not widely available, many empirical relationships have been derived to link the kinetic energy and intensity (I) of rainfall, the factor that has the most control over soil erosion and is readily accessible. This study considered three rainfall erosivity indices: kinetic energy expenditure (KE<SUB>time</SUB>, J m<SUP>-2</SUP> h<SUP>-1</SUP>), kinetic energy content (KE<SUB>mm</SUB>, J m<SUP>-2</SUP> mm<SUP>-1</SUP>), and momentum (M, kg m s<SUP>-1</SUP> m<SUP>-2</SUP> s<SUP>-1</SUP> or N m<SUP>-2</SUP>). The relationships between these rainfall erosivity indices (KE<SUB>time</SUB>, KE<SUB>mm</SUB>, and M) and rainfall intensity were established by fitting to an existing functional model based on measurements of the number of drops by size and terminal velocity made from January 2010 to July 2011 using a laser optical disdrometer in Daejeon City, Korea. The best fit for the relationship between the three kinetic energy indices and rainfall intensity was obtained with a power law (KE<SUB>time</SUB>-I, and M-I) and an exponential model (KE<SUB>mm</SUB>-I). Validation results for two different events indicated good performance for the KE<SUB>time</SUB>-I and M-I equations, with a similar distribution of observed data and power-law curve fitting. However, the rainfall momentum index produced much lower uncertainty as determined from the measured terminal velocity when the equipment was exposed to in situ changeable conditions. Therefore, we suggest that the power-law relationship between momentum and rainfall intensity is the most suitable equation for the prediction of rainfall erosivity.

Effects of dextrorotatory morphinans on brain Na⁺ channels expressed in Xenopus oocytes

Lee, J.H.,Shin, E.J.,Jeong, S.M.,Lee, B.H.,Yoon, I.S.,Lee, J.H.,Choi, S.H.,Kim, Y.H.,Pyo, M.K.,Lee, S.M.,Chae, J.S.,Rhim, H.,Oh, J.W.,Kim, H.C.,Nah, S.Y. North-Holland ; Elsevier Science Ltd 2007 european journal of pharmacology Vol.564 No.1

We previously demonstrated that dextromethorphan (DM; 3-methoxy-17-methylmorphinan) analogs have neuroprotective effects. Here, we investigated the effects of DM, three of its analogs (DF, 3-methyl-17-methylmorphinan; AM, 3-allyloxy-17-methoxymorphian; and CM, 3-cyclopropyl-17-methoxymorphinan) and one of its metabolites (HM; 3-methoxymorphinan), on Na<SUP>+</SUP> channel activity. We used the two-microelectrode voltage-clamp technique to test the effects of DM, DF, AM, CM and HM on Na<SUP>+</SUP> currents (I<SUB>Na</SUB>) in Xenopus oocytes expressing cRNAs encoding rat brain Nav1.2 α and β1 or β2 subunits. In oocytes expressing Na<SUP>+</SUP> channels, DM, DF, AM and CM, but not HM, induced tonic and use-dependent inhibitions of peak I<SUB>Na</SUB> following low- and high-frequency stimulations. The order of potency for the inhibition of peak I<SUB>Na</SUB> was AM-CM > DM=DF. The DM, DF, AM and CM-induced tonic inhibitions of peak I<SUB>Na</SUB> were voltage-dependent, dose-dependent and reversible. The IC<SUB>50</SUB> values for DM, DF, AM and CM were 116.7+/-14.9, 175.8+/-16.9, 38.6+/-15.5, and 42.5+/-8.5 μM, respectively. DM and its analogs did not affect the steady-state activation and inactivation voltages. AM and CM, but not DM and DF, inhibited the plateau I<SUB>Na</SUB> more effectively than the peak I<SUB>Na</SUB> in oocytes expressing inactivation-deficient I1485Q-F1486Q-M1487Q (IFMQ3) mutant channels; the IC<SUB>50</SUB> values for AM and CM in this system were 8.4+/-1.3 and 8.7+/-1.3 μM, respectively, for the plateau I<SUB>Na</SUB> and 43.7+/-5.9 and 32.6+/-7.8 μM, respectively, for the peak I<SUB>Na</SUB>. These results collectively indicate that DM and its analogs could be novel Na<SUP>+</SUP> channel blockers acting on the resting and open states of brain Na<SUP>+</SUP> channels.

A systematic investigation of the thermoelectric stability of Pt–Rh thermocouples between 1300 °C and 1500 °C

Pearce, J V,Edler, F,Elliott, C J,Greenen, A,Harris, P M,Izquierdo, C Garcia,Kim, Y-G,Martin, M J,Smith, I M,Tucker, D,Veltcheva, R I BUREAU INTERNATIONAL DES POIDS ET MESURES 2018 METROLOGIA -BERLIN- Vol.55 No.4

<P>By using a simple model to relate the electromotive force drift rate of Pt–Rh thermoelements to d<I>S</I>/d<I>c</I>, i.e. the sensitivity of the Seebeck coefficient, <I>S</I>, to rhodium mass fraction, <I>c</I>, the composition of the optimal pair of Pt–Rh wires that minimizes thermoelectric drift can be determined. The model has been applied to four multi-wire thermocouples each comprising 5 or 7 Pt–Rh wires of different composition. Two thermocouples were exposed to a temperature of around 1324 °C, one thermocouple to around 1492 °C, i.e. the melting points of the Co–C and Pd–C high temperature fixed points, respectively, and one thermocouple to a series of temperatures between 1315 °C and 1450 °C. The duration of exposure at each temperature was several thousand hours. By performing repeated calibrations <I>in situ</I> with the appropriate fixed point during the high temperature exposure, the drift performance has been quantified with high accuracy, entirely free from errors associated with thermoelectric homogeneity. By combining these results it is concluded that the Pt-40%Rh versus Pt-6%Rh is the most stable at the temperatures investigated. A preliminary reference function was determined and is presented.</P>

Assessing Mobile Location-Based Service (m-LBS) Quality: A Combination of m-LBS Quality Scale and Importance-Performance Analysis

M. Mujiya Ulkhaq,Auni W. I. Pertiwi,Lakshita Pritandari,M. Taufik Aditya 대한산업공학회 2020 Industrial Engineeering & Management Systems Vol.19 No.3

The popularity of personal navigation devices and mapping services have made the society utilizes certain locationbased ideas and their applications. With the convenience of using smart phones, it could create an opportunity for the development of mobile location-based service (m-LBS) in order to bring personalized values to the users. Consequently, it leads to a fierce competition among the providers of the m-LBS applications; thus, they have to improve their service qualities in order to fulfill the customers’ needs. This study tried to assess the m-LBS quality using the m-LBS quality scale and combine it with the importance-performance analysis (IPA) model. The m-LBS quality scale has been shown to be statistically reliable and valid for use in measuring the m-LBS quality. However, assessing the service quality per se is considered not sufficient since the service providers have to prioritize the aspects they want to improve. It has to be done since they are constrained by limitations on the resources they have. The IPA model, on the other hand, is regarded as an effective method to find out particular aspects that performed poorly but are highly important. A case study to exhibit the applicability of the proposed method was conducted in one of the biggest motorcycles-based transport services in Indonesia.