The Development of High-Current Power Supply System for Electrolytic Copper Foil

An Luo,Fujun Ma,Qiaopo Xiong,Zhixing He 전력전자학회 2015 JOURNAL OF POWER ELECTRONICS Vol.15 No.2

A 6.5 V/50 kA high-frequency switching power supply (HSPS) system composed of 10 power modules is developed to meet the requirements of copper-foil electrolysis. The power module is composed of a two-leg pulse width modulation (PWM) rectifier and a DC/DC converter. The DC/DC converter adopts two full-wave rectifiers in parallel to enhance the output. For the two-leg PWM rectifier, the ripple of the DC-link voltage is derived. A composite control method with a ripple filter is then proposed to effectively improve the performance of the rectifier. To meet the process demand of copper-foil electrolysis, the virtual impedance-based current-sharing control method with load current full feedforward is proposed for n-parallel DC/DC converters. The roles of load current feedforward and virtual impedance are analyzed, and the current-sharing control model of the HSPS system is derived. Virtual impedance is used to adjust the current-sharing impedance without changing the equivalent output impedance, which can effectively reduce current-sharing errors. Finally, simulation and experimental results verify the structure and control method.

A New 5α,8α-Epidioxy Sterol from a Marine Sponge Psammocinia Species

Hye Jin Park1,,Xuan Luo1,,Jongki Hong2,,Dong-kyoo Kim3,,Kwang Sik Im1, and,Jee H. Jung1* 한국생약학회 2005 Natural Product Sciences Vol.11 No.4

An investigation of the MeOH soluble fractions of a marine sponge Psammocinia sp. (Order:Dictyoceratida) led to the isolation of a new epidioxy sterol (1) and four known sterols (2-5). Their planarstructures were defined by analyses of the spectroscopic data. The 27-nor-24-methylcholestan type side chain withan epidioxy nucleus (1) was unprecedented. Compounds 1-5 were isolated from a sponge Psammocinia sp. for the first time.

Polymorphisms of Ionotropic Glutamate Receptor-Related Genes and the Risk of Autism Spectrum Disorder in a Chinese Population

Xinyan Xie,Fang Hou,Li Li,Yanlin Chen,Lingfei Liu,Xiu Luo1,Huaiting Gu,Xin Li,Jiajia Zhang,Jianhua Gong,Ranran Song 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.5

Objective: To evaluate the association of GRIK2 and NLGN1 with autism spectrum disorder in a Chinese population. Methods: We performed spatio-temporal expression analysis of GRIK2 and NLGN1 in the developing prefrontal cortex, and examined the expression of the genes in ASD cases and healthy controls using the GSE38322 data set. Following, we performed a case-control study in a Chinese population. Results: The analysis using the publicly available expression data showed that GRIK2 and NLGN1 may have a role in the development of human brain and contribute to the risk of ASD. Later genetic analysis in the Chinese population showed that the GRIK2 rs6922753 for the T allele, TC genotype and dominant model played a significant protective role in ASD susceptibility (respectively: OR=0.840, p=0.023; OR=0.802, p=0.038; OR=0.791, p=0.020). The NLGN1 rs9855544 for the G allele and GG genotype played a significant protective role in ASD susceptibility (respectively: OR=0.844, p=0.019; OR=0.717, p=0.022). After adjusting p values, the statistical significance was lost (p>0.05). Conclusion: Our results suggested that GRIK2 rs6922753 and NLGN1 rs9855544 might not confer susceptibility to ASD in the Chinese population.

Effect of Baseline Resistance-associated Variants on SVR with the 3D Regimen with and without RBV in GT1a and GT1b-infected Patients

( Christoph Sarrazin ),( Mark S. Sulkowski ),( Preethi Krishnan ),( Rakesh Tripathi ),( Gretja Schnell ),( Yan Xie ),( Daniel E. Cohen ),( Roger Trinh ),( Lino Rodrigues-jr. ),( Yan Luo3,Nancy S. Shul 대한간학회 2016 춘·추계 학술대회 (KASL) Vol.2016 No.1

Aims: The 3 direct-acting antiviral (3-DAA) regimen of ombitasvir, ritonavir-boosted paritaprevir and dasabuvir ± RBV is approved in the US and EU for treatment of hepatitis C virus (HCV) genotype (GT) 1 infection. Baseline resistance associated variants (RAVs) in HCV NS3 or NS5A can impact response to other DAA regimens; we assessed the prevalence and impact of RAVs on response to the 3-DAA regimen. Methods: Next-generation sequencing (Illumina MiSeq) assessed baseline samples from treatment-naive (PEARL-IV), -experienced (SAPPHIRE- II), or cirrhotic (TURQUOISE-II) GT1a patients who received 3-DAA + RBV, and treatment-experienced (PEARL-II) or cirrhotic (TURQUOISE-III) GT1b patients who received 3-DAA alone. Thresholds of 1 and 15%, respectively, detected the prevalence and impact of baseline RAVs; impact of RAVs conferring ≥ 5-fold resistance to components of the 3-DAA regimen on response was determined by com- paring SVR rates in patients with or without RAVs. Results: SVR rates were 96% and 100% in patients with GT1a and GT1b, respectively. One or more NS5A RAVs were present in 11% of treatment-experienced or cirrhotic GT1a patients, whereas NS5A RAVs were found in 19% of GT1b patients (15% threshold). Similar SVR rates were seen in GT1a patients with or without NS5A RAVs. All GT1b patients with NS5A RAVs, including at position Y93, achieved SVR. NS3 RAVs were uncommon (≤2%). NS3 RAVs were not seen in any of the 14 virologic failures and an NS5B RAV was seen in 1 virologic failure. The presence of the GT1a NS3 Q80K polymorphism had no impact on SVR. Conclusions: Understanding impact of baseline NS5A RAVs on treatment outcomes is important for relevant HCV therapies. Patients with HCV GT1a-infection treated with the 3-DAA regimen + RBV achieved high SVR rates, regardless of the presence of baseline RAVs. All GT1b patients treated with the 3-DAA regimen alone achieved SVR.

The Historical Development of Hindu Nationalism in India

Andi Luo(Andi Luo),Haiyang He(Haiyang He),Fang Luo(Fang Luo) 아시아사회과학학회 2023 Jornal of Asia Social Science Vol.10 No.1

Hindu nationalism has played a significant role in shaping the political and social landscape of India throughout its history. This paper examines the development of Hindu nationalism in India, from its emergence during the colonial period to its current state in post-independence India. The paper also analyzes the challenges and criticisms associated with Hindu nationalism, including its impact on the principles of secularism and democracy, religious violence and communalism, and the rights and freedoms of minority groups. The paper concludes by discussing the need for greater understanding and tolerance between different religious and cultural groups in India and the importance of promoting a more inclusive and diverse society.

韓愈와 柳宗元의 작문 경쟁

羅聯添(Lian-Tian Luo),金智英(번역자) 중국어문논역학회 2017 中國語文論譯叢刊 Vol.0 No.41

본고는 羅联添이 1992년에 발표한 <論韓愈古文幾個問題>의 제4장 “韓愈와 柳宗元이 고문으로 서로 경쟁함(韓柳爲文相角)” 부분을 번역한 것이다. 한유와 유종원의 글이 유사하다거나 경쟁적이라는 견해는 예전부터 있어왔다. 이런 주장은 송대의 羅大經, 명대의 孫礦, 청대의 林云銘, 근대의 錢基博이 제기한 바 있다. 필자는 한유와 유종원의 작문 경쟁에 대한 이전의 정황을 검토하고, 이전에 언급되지 않았던 다른 작품들을 예로 들어 한유와 유종원의 글쓰기에 확실히 경쟁심리가 있었음을 증명하였다. 즉 한유와 유종원의 작품 가운데 서로의 작품을 의식하면서 경쟁적으로 쓴 29조의 작품을 예로 들며, 창작 연대와 주요 내용을 설명하고 그 증거를 제시하였다. 경쟁했던 작품을 종합해 보니 두 사람의 작품 중 시기를 확정할 수 있는 작품 가운데 한유가 유종원 보다 앞서 지은 작품이 월등히 많았다. 이로써 유종원이 고문 창작에 있어 한유와 경쟁하려는 의도가 많았고, 한유가 유종원과 경쟁하려 한 것은 적었음을 알 수 있다. 이 점은 또한 한유가 고문 창작에서 주도적인 지위를 차지하고 있었음을 분명히 보여준다. 후인들이 한유를 당송고문운동의 으뜸으로 추앙하는 데에는 그만한 까닭이 있는 것이다. This paper is a translation of Han-Yu and Liu Zong-yuan’s writing competition in Chapter 4 of Luo Lian-tian’s <論韓愈古文的幾個問題>. The view that Han-Yu and Liu Zong-yuan’s writings are similar or competitive has been around for a long time. These claims were made by Luo Da-jing of Song Dynasty, Sun-Kuang of Ming Dynasty, Lin Yun-ming of Qing Dynasty, and Qian Ji-bo of modern times. I reviewed the previous context of Han-Yu and Liu Zong-yuan’s writing competition and proved that there was a clear competition in their writings by taking other works not mentioned before. I took examples the twenty - nine articles which compete with each other while conscious of their works among the works of Han-Yu and Liu Zong-yuan, in a chronological order Among the works that we can confirm the timing of the works of two people, Han-Yu had much more works than Liu Zong-yuan. This shows that Liu Zong-yuan intends to compete with Han-Yu for the Composition of the ancient writing, and that Han-Yu did not try to compete with Liu Zong-yuan. This also clearly shows that Han-Yu was in a leading position in the Composition of the ancient writing. There is a clear reason why the posterity pay reverence to Han-Yu as the forerunner of the Composition of the ancient writing movement.

DC 마그네트론 Co-sputtering 시스템을 이용하여 증착한 GAZO 박막의 전기적 및 구조적 특성

Luo Jie(Jie Luo),박세훈(Se-hun Park),송풍근(Pung-keun Song) 한국표면공학회 2009 한국표면공학회지 Vol.42 No.3

Ga/Al doped ZnO (GAZO) thin films were prepared on non-alkali glass substrate by co-sputtering system using two DC cathodes equipped with AZO (Al2O3:2.0 wt%) target and GZO (Ga₂O₃:6.65 wt%) target. This study examined the influence of Al/Ga concentration and substrate temperature on the electrical, structural and optical properties of GAZO films. The lowest resistivity 1.95×10<SUP>?3</SUP> Ω㎝ was obtained at room temperature. With increasing substrate temperature, resistivity of GAZO film decreased to a minimum value of 7.47×10<SUP>?4</SUP>Ω㎝ at below 300℃. Futhermore, when 0.05% H₂ gas was introduced, resistivity of GAZO film decreased to 6.69×10<SUP>?4</SUP>Ω㎝. All the films had a preferred orientation along the (002) direction, indicating that the deposited films have hexagonal wurtzite structure formed by the textured growth along the c-axis. The average transmittance of the films was more than 85% in the visible light range.

The Nonlinear Effect of Population Aging and Socio-economic Conditions on Carbon Emission: An Empirical Analysis of 30 Provinces and Regions in China

Luo Zhenxing(Zhenxing Luo),Zhao Yanwei(Yanwei Zhao),Lim Jungmin(Jungmin Lim) 한국자료분석학회 2023 Journal of the Korean Data Analysis Society Vol.25 No.3

The central aim of this paper is to provide a comprehensive analysis of the impact of population aging on carbon emissions in China. In order to attain a deeper comprehension of this effect, this study investigates the non-linear relationship between population aging and carbon emissions through empirical analysis of 30 provinces and regions in China from 1997 to 2019 using a panel threshold model. Our primary research findings indicate that the correlation between population aging and carbon emissions demonstrates nonlinearity. Population aging has had an inhibitory effect on carbon emissions; however, as the aging population continues to increase, its effect on suppressing carbon emissions will weaken. Moreover, we have also uncovered non-linear relationships between energy intensity, per capita GDP, industrial structure, and carbon emissions. Notably, despite rapid growth in total fossil energy consumption, energy intensity has shown a decreasing trend in China, which has mitigated the upsurge in carbon emissions attributed to fluctuations in energy intensity. The positive correlation between GDP per capita and carbon emissions is evident, but there is little variation observed across different threshold levels. Finally, the relationship between industrial structure and carbon emissions is considerably intricate, our results show that a U-shaped curvilinear relationship exists between the two variables.

Autophagy Inhibition Promotes Gambogic Acid-induced Suppression of Growth and Apoptosis in Glioblastoma Cells

Luo, Guo-Xuan,Cai, Jun,Lin, Jing-Zhi,Luo, Wei-Shi,Luo, Heng-Shan,Jiang, Yu-Yang,Zhang, Yong Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12

Objective: To investigate the effects of gambogic acid (GA) on the growth of human malignant glioma cells. Methods: U251MG and U87MG human glioma cell lines were treated with GA and growth and proliferation were investigated by MTT and colony formation assays. Cell apoptosis was analyzed by annexin V FITC/PI flow cytometry, mitochondrial membrane potential assays and DAPI nuclear staining. Monodansylcadaverine (MDC) staining and GFP-LC3 localisation were used to detect autophagy. Western blotting was used to investigate the molecular changes that occurred in the course of GA treatment. Results: GA treatment significantly suppressed cell proliferation and colony formation, induced apoptosis in U251 and U87MG glioblastoma cells in a time- and dose-dependent manner. GA treatment also lead to the accumulation of monodansylcadaverine (MDC) in autophagic vacuoles, upregulated expressions of Atg5, Beclin 1 and LC3-II, and the increase of punctate fluorescent signals in glioblastoma cells pre-transfected with GFP-tagged LC3 plasmid. After the combination treatment of autophagy inhitors and GA, GA mediated growth inhibition and apoptotic cell death was further potentiated. Conclusion: Our results suggested that autophagic responses play roles as a self-protective mechanism in GA-treated glioblastoma cells, and autophagy inhibition could be a novel adjunctive strategy for enhancing chemotherapeutic effect of GA as an anti-malignant glioma agent.

LncRNA TMPO-AS1 promotes esophageal squamous cell carcinoma progression by forming biomolecular condensates with FUS and p300 to regulate TMPO transcription

Luo Xiao-Jing,He Ming-Ming,Liu Jia,Zheng Jia-Bo,Wu Qi-Nian,Chen Yan-Xing,Meng Qi,Luo Kong-Jia,Chen Dong-Liang,Xu Rui-Hua,Zeng Zhao-Lei,Liu Ze-Xian,Luo Hui-Yan 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

Esophageal squamous cell carcinoma (ESCC) is one of the most life- and health-threatening malignant diseases worldwide, especially in China. Long noncoding RNAs (lncRNAs) have emerged as important regulators of tumorigenesis and tumor progression. However, the roles and mechanisms of lncRNAs in ESCC require further exploration. Here, in combination with a small interfering RNA (siRNA) library targeting specific lncRNAs, we performed MTS and Transwell assays to screen functional lncRNAs that were overexpressed in ESCC. TMPO-AS1 expression was significantly upregulated in ESCC tumor samples, with higher TMPOAS1 expression positively correlated with shorter overall survival times. In vitro and in vivo functional experiments revealed that TMPO-AS1 promotes the proliferation and metastasis of ESCC cells. Mechanistically, TMPO-AS1 bound to fused in sarcoma (FUS) and recruited p300 to the TMPO promoter, forming biomolecular condensates in situ to activate TMPO transcription in cis by increasing the acetylation of histone H3 lysine 27 (H3K27ac). Targeting TMPO-AS1 led to impaired ESCC tumor growth in a patient-derived xenograft (PDX) model. We found that TMPO-AS1 is required for cell proliferation and metastasis in ESCC by promoting the expression of TMPO, and both TMPO-AS1 and TMPO might be potential biomarkers and therapeutic targets in ESCC.