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Mammographic Screening of Women Attending a Reference Service Center in Southern Brazil
Lopes, Tiara Cristina Romeiro,Gravena, Angela Andreia Franca,de Oliveira Demitto, Marcela,Brischiliari, Sheila Cristina Rocha,Borghesan, Deise Helena Pelloso,Agnolo, Catia Millene Dell,de Barros Carva Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.3
Background: To investigate the prevalence of and factors associated with performance of annual mammography by women above 40 years of age. Materials and Methods: This cross-sectional retrospective study was conducted at an oncology reference service in Southern Brazil from October 2013 to October 2014 with 525 women aged 40 years or older. Results: The prevalence of annual mammography was 54.1%; annual mammographic screening was performed for women without private medical insurance, who were under hormone replacement therapy and who had used contraception in the past. An association was found between non-performance of breast clinical and self-examination and non-performance of mammographic screening. Conclusions: Use of mammography for breast cancer screening in the public health care setting proved to be accessible; nevertheless, the proportion of screened women was low, and they exhibited poor adherence to the basic measures of care recommended for breast assessment. Thus, control of breast cancer requires implementing actions targeting the population most vulnerable to non-adherence to screening in addition to continuously monitoring and assessing that population to reduce the prevalence of this disease.
Lopes, M.F.P.,Paixao Conde, J.M.,Gomes, M. Gloria,Ferreira, J.G. Techno-Press 2010 Wind and Structures, An International Journal (WAS Vol.13 No.6
When designing structures to the wind action, the variation of the mean wind velocity and turbulence parameters with the height above the ground must be taken into account. This paper presents the numerical simulation results of atmospheric boundary layer (ABL) airflows, in a numerical domain with no obstacles and with a cubic building. The results of the flow characterization, obtained with the FLUENT CFD code were performed using the ${\kappa}-{\varepsilon}$ turbulence model with the MMK modification. The mean velocity and turbulence intensity profiles in the inflow boundary were defined in accordance with the Eurocode 1.4, for different conditions of aerodynamic roughness. The maintenance of the velocity and turbulence characteristics along the domain were evaluated in an empty domain for uniform incident flow and the ABL Eurocode velocity profiles. The pressure coefficients on a cubic building were calculated using these inflow conditions.
Lateral pterygoid muscle volume and migraine in patients with temporomandibular disorders
Lopes, Sergio Lucio Pereira De Castro,Costa, Andre Luiz Ferreira,Gamba, Thiago De Oliveira,Flores, Isadora Luana,Cruz, Adriana Dibo,Min, Li Li Korean Academy of Oral and Maxillofacial Radiology 2015 Imaging Science in Dentistry Vol.45 No.1
Purpose: Lateral pterygoid muscle (LPM) plays an important role in jaw movement and has been implicated in Temporomandibular disorders (TMDs). Migraine has been described as a common symptom in patients with TMDs and may be related to muscle hyperactivity. This study aimed to compare LPM volume in individuals with and without migraine, using segmentation of the LPM in magnetic resonance (MR) imaging of the TMJ. Materials and Methods: Twenty patients with migraine and 20 volunteers without migraine underwent a clinical examination of the TMJ, according to the Research Diagnostic Criteria for TMDs. MR imaging was performed and the LPM was segmented using the ITK-SNAP 1.4.1 software, which calculates the volume of each segmented structure in voxels per cubic millimeter. The chi-squared test and the Fisher's exact test were used to relate the TMD variables obtained from the MR images and clinical examinations to the presence of migraine. Logistic binary regression was used to determine the importance of each factor for predicting the presence of a migraine headache. Results: Patients with TMDs and migraine tended to have hypertrophy of the LPM (58.7%). In addition, abnormal mandibular movements (61.2%) and disc displacement (70.0%) were found to be the most common signs in patients with TMDs and migraine. Conclusion: In patients with TMDs and simultaneous migraine, the LPM tends to be hypertrophic. LPM segmentation on MR imaging may be an alternative method to study this muscle in such patients because the hypertrophic LPM is not always palpable.
Intake, digestibility, and performance of lambs fed spineless cactus cv. Orelha de Elefante Mexicana
Lopes Levi Auto,Ferreira Marcelo de Andrade,Batista Ângela Maria Vieira,Maciel Michel do Vale,de Andrade Rodrigo Barbosa,Munhame Joana Albino,Silva Tomás Guilherme Pereira da,Cardoso Daniel Barros,Vér 아세아·태평양축산학회 2020 Animal Bioscience Vol.33 No.8
Objective: To evaluate the effects of the carmine cochineal-resistant spineless cactus genotypes cv. Orelha de Elefante Mexicana (Opuntia) and Miúda (Nopalea) on the intake and digestibility of nutrients, ingestive behavior, performance, and ultrasound measurements of growing lambs. Methods: Thirty-six male (non-castrated) Santa Inês lambs were used, with an average age of 6 months and an initial average weight of 22.0±2.9 kg. They were distributed in a completely randomized design with 3 treatments (Tifton hay, Nopalea and Opuntia) and 12 replications, using initial weight as a covariate. The experimental period was 86 days, with the first 30 days used for the adaptation of the animals to the facilities, diets and management, and the remaining 56 days used for evaluation and data collection. Results: The intake and apparent digestibility of dry matter (DM), organic matter (OM), crude protein (CP), neutral detergent fiber (NDF), total carbohydrates (TC), non-fibrous carbohydrates (NFC), and total digestible nutrients (TDN) showed a significant difference (p<0.05) as a function of the diets, with the Nopalea treatment (p<0.05) increasing DM intake (g/kg and % body weight [BW]), CP, TDN, and TC digestibility, whereas the Tifton hay diet led to a high (p<0.001) neutral detergent fiber corrected for ash and protein (NDFap) g/d intake, NDFap (BW %) and digestibility of said nutrient. There was no effect of treatments (p>0.05) on feeding time, however, rumination time and total chewing time were higher (p<0.05) for animals fed Tifton hay. The performance of the animals was similar (p>0.05). For the ultrasound measurements, Nopalea promoted an increase in the final loin eye area, compared to Tifton hay. Conclusion: The use of spineless cactus variety Miúda leads to the greater intake and digestibility of nutrients. The evaluated carmine cochineal-resistant spineless cactus genotypes are alternatives for semi-arid regions as they do not negatively affect the performance of growing lambs.
Renato Lopes da Costa,Nélson Santos Antonio 동아시아경상학회 2014 The East Asian Journal of Business Economics Vol.2 No.3
Although management consulting activities have obtained a considerable growth in terms of economic significance in recent years, these results have not been duly followed by a greater number of conceptual and empirical research in this area. In order to fight the lack of studies on the actual work of management consultants, this article aims at answer some questions that remain open. Is management consulting an intensive and specialized knowledge activity? Are there knowledge and learning key success factors in this area? Are consultants the real experts and the true practitioners of strategy as practice? The results of the empirical analysis in the form of semi-structured interviews and questionnaires given to management consultants and SME managers in Portugal shows that management consulting is founded on a knowledge-intensive base, although consultants cannot be called strategy practitioners as many authors call them. This is illustrated by the Portuguese model of determinants that constitute the management consulting industry presented in this article, which means this proposition is a new direction in strategic thinking in what the field's research strategy-as-practice concerns.
N. Lopes,P. Piloto,P.M.M. Vila Real,L. Simões da Silva,J.-M. Franssen 국제구조공학회 2003 Steel and Composite Structures, An International J Vol.3 No.6
Two new formulae for the design of beam-columns at room temperature have been proposed into Eurocode 3, prEN 1993-1-1 (2002), and are the result of great efforts made by two working groups that followed different approaches, a French-Belgian team and an Austrian-German one. Under fire conditions the prEN 1993-1-2 (structural fire design) presents formulae, for the design of beam-columns based on the prENV 1993-1-1 (1992). In order to study the possibility of having, in part 1-1 and part 1-2 of the Eurocode 3, the same approach, a numerical research was made using the finite element program SAFIR, developed at the University of Liege for the study of structures subjected to fire.
Gastroprotective Activity of Neoglaziovia variegata (Arruda) Mez. (Bromeliaceae) in Rats and Mice
Kamila Lopes de Lira,Flávia Danniele Frota Machado,Ana Flávia Seraine Custódio Viana,Irisdalva Sousa Oliveira,Francilene Vieira da Silva,Hélio de Barros Fernandes,Jackson Roberto Guedes da Silva Almei 한국식품영양과학회 2021 Journal of medicinal food Vol.24 No.10
Neoglaziovia variegata (Arruda) Mez (Bromeliaceae) is a medicinal plant popularly known as “caroá.” The leaves are made up of highly resistant fibers, which is of great commercial value to the handicraft and textile industry. Some studies have demonstrated that ethanolic extract of N. variegata have gastroprotective properties. This study aimed to investigate the gastroprotective activity and cytoprotective mechanisms of ethyl acetate (Nv-AcOEt), hexane (Nv-Hex), and chloroform (Nv-CHCl3) fractions of N. variegata leaves. The gastroprotective activity of Nv-AcOEt, Nv-Hex, and Nv-CHCl3 was evaluated using the ethanol and ethanol/HCl-induced gastric injury model. To elucidate the gastroprotective mechanisms, the functions of prostaglandins (PGs), nitric oxide (NO), and KATP channels were evaluated. In addition, the nonprotein sulfhydryl groups and the mucus content in the gastric tissues were analyzed. All fractions of N. variegata leaves at oral doses of 100, 200, and 400 mg/kg significantly decreased ethanol and ethanol/HCl-induced gastric lesions, leading to gastroprotection, accompanied by an increase in reduced glutathione (GSH) and gastric mucus. Gastroprotective activity of Nv-AcOEt was inhibited after pretreatment with ibuprofen and N(G)-nitro-L-arginine (L-NOARG). Gastroprotective effect of Nv-Hex and Nv-CHCl3 was also inhibited after pretreatment with L-NOARG and with glibenclamide. The results indicate that N. variegata (Arruda) Mez exhibits promising gastroprotective activity with the possible participation of NO, PGs, mucus, sulfhydryl groups, and KATP.
Experimental Behaviour of the Reverse Channel Joint Component at Elevated and Ambient Temperatures
Fernanda Lopes,Aldina Santiago,Luís Simões da Silva,Tim Heistermann,Milan Veljkovic,José Guilherme da Silva 한국강구조학회 2013 International Journal of Steel Structures Vol.13 No.3
The reverse channel connection appears to have the best combination of desirable features under fire loading: moderate construction cost, ability to develop catenary action and extremely high ductility through deformation of the web channel (Ding and Wang, 2007). This paper presents the results of an experimental investigation of a reverse channel component conducted at the University of Coimbra as part of the European RFCS COMPFIRE Project, the main focus of which is to characterise the behaviour of steel joints that connect steel beams to concrete-filled tubular columns under natural fire loading. A series of tensile and compressive tests at ambient and elevated temperatures was conducted. The purposes of the experimental tests were to characterise the strength, stiffness and ductility of this joint component and to establish a relationship between force,displacement and temperature.
ATP13A2 and Alpha-synuclein: a Metal Taste in Autophagy
Tomás Lopes da Fonseca,Tiago Fleming Outeiro 한국뇌신경과학회 2014 Experimental Neurobiology Vol.23 No.4
Parkinson’s Disease (PD) is a complex and multifactorial disorder of both idiopathic and genetic origin. Thus far, more than 20 geneshave been linked to familial forms of PD. Two of these genes encode for ATP13A2 and alpha-synuclein (asyn), proteins that seemto be members of a common network in both physiological and disease conditions. Thus, two different hypotheses have emergedsupporting a role of ATP13A2 and asyn in metal homeostasis or in autophagy. Interestingly, an appealing theory might combinethese two cellular pathways. Here we review the novel findings in the interaction between these two proteins and debate the excitingroads still ahead.
Brain Neuroplasticity after Treatment with Antiseizure: A Review
Débora Lopes Silva de Souza,Hosana Mirelle Goes e Silva Costa,Francisca Idalina Neta,Paulo Leonardo Araujo de Gois Morais,Luís Marcos de Medeiros Guerra,Fausto Pierdoná Guzen,Lucídio Clebeson de Olive 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.4
Epilepsy is a disease characterized by the periodic occurrence of seizures. Seizures can be controlled by antiseizure medications, which can improve the lives of individuals with epilepsy when given proper treatment. Therefore, this study aimed to review the scientific literature on brain neuroplasticity after treatment with antiseizure drugs in different regions of the brain. According to the findings, that several antiseizure, such as lamotrigine, diazepam, levetiracetam, and valproic acid, in addition to controlling seizures, can also act on neuroplasticity in different brain regions. The study of this topic becomes important, as it will help to understand the neuroplastic mechanisms of these drugs, in addition to helping to improve the effectiveness of these drugs in controlling the disease.