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- 저자 : Leon Morales-Quezada (검색결과 1 건)
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A Preliminary Study on qEEG in Burn Patients With Chronic Pruritus
Fiorella K. Miraval,Vivian L. Shie,Leon Morales-Quezada,Carolina Santiago,Bianca Fernandes-Marcondes,Deborah Nadler,Colleen M. Ryan,Jeffrey C. Schneider,Felipe Fregni 대한재활의학회 2017 Annals of Rehabilitation Medicine Vol.41 No.4
Objective To explore and determine the reorganizational changes in the cortical neural circuits associated with pruritis, this study was undertaken to compare the electroencephalography (EEG) changes in burn patients having primary symptoms of chronic itching (pruritis) and their paired healthy subjects. Methods Eight subjects were recruited for this exploratory pilot study: 4 patients with pruritus after burn injury matched by gender and age with 4 healthy subjects. EEG recordings were analyzed for absolute alpha, low beta, high beta, and theta power for both groups. Results The mean age of the burn patients was 41.75 years; while the mean age for the matched healthy subjects was 41.5 years. All subjects were male. A decreased alpha activity was observed in the occipital channels (0.82 vs. 1.4; p=0.01) and a decreased low beta activity in the frontal area (0.22 vs. 0.4; p=0.049) in eyes closed conditions. An overall decreased theta trend was observed in both the eyes open and eyes closed conditions in burn patients, compared to healthy individuals.Conclusion This preliminary study presents initial evidence that chronic pruritus in burn subjects may be associated with brain reorganizational changes at the cortical level characterized by an EEG pattern.
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