갱년기 여성의 호르몬 대치 요법에 대한 수용율

이임순,장진영,이정재,이순곤,이권해,이해혁,김승형 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

Purpose: We have evaluated the compliance of hormone replacement therapy. Method: There are 185 climacteric women who are divided into three groups (Group I, Group II, Group III). Group I is given conjugated equine estrogen(CEE, 0.625mg, day 1-30) plus medroxyprogesterone acetate(MPA, 5mg, day 1-12). Group II is given conjugated equine estrogen (CEE, 0.625mg, day 1-30) plus medroxyprogesterone acetate (MPA, 2.5mg, day 1-30), Group III is given only conjugated equine estrogen(CEE, 0.625mg, day 1-30). Results: 1) The compliance rate of hormone replacement therapy during three months is 77.9% including each Group I : 77.7%, Group Ⅱ : 76.1%, Group Ⅲ :80.4%. 2) The compliance rate of hormone replacement therapy during six months is 60.7% including each Group Ⅰ:52.9%, Group Ⅱ: 56.4%, Group Ⅲ: 79.5%. 3) The compliance rate of hormone replacement therapy during nine months is 49.7% including each Group Ⅰ: 45.5%, Group Ⅱ:41.7%, Group Ⅲ: 64.3%. 4) The compliance rate of hormone replacement therapy during a year is 44.4% including each Group Ⅰ: 40.2%, Group Ⅱ:35.3%, Group Ⅲ: 59.5%. Conclusion : It is vital that we maximize compliance if patients are to receive the full benefits from hormone replacement therapy. We think that physicians who prescribe hormone replacement therapy for climacteric women should enough explain the purpose, risks, and side effect of treatment for maximizing compliance of hormone replacement therapy.

정신분열증과 우울증의 지각결핍의 비교

이수형,송경의,이형영,하형욱 大韓神經精神醫學會 1984 신경정신의학 Vol.23 No.4

정신분열증 환자의 지각결핍을 타 질환군과 비교해 보기 위하여 1983.6.1부터 동년 8월 31일 까지 전남의 대병원 정신과 외래에 다니는 우울증 환자 20명 국립나주정신병원에 입원한 정신분열증 환자 20명을 임의 선택하여 Garner의 모형을 이용 카드 분류를 시행하고 그 자료를 토대로 수정분류시간, 공제지수, 비율지수 등을 산출하여 변량분석한 결과 다음과 같은 결론을 얻었다. 1. 양 군의 수정시간을 변량 분석한 결과 유의한 차이를 발견할 수 없었다. 2. 공제지수와 비율지수를 변량분석한 결과 과다성 분류와 여과분류에서는 공제지수와 비율지수에서 아무런 유의차가 없었다. 3. 주사분류에서는 공제지수 비교에서 1% 수준에서 비율지수 비교에서 5% 수준으로 우울증의 분류시간이 긴 것으로 나타났다. 이상의 결과를 살펴볼 때 여과기능의 결함이라는 지각결핍은 정신분열증의 고유한 장애가 아닐 수도 있겠다. The perception of stimuli with two dimensions (size and figure) was investigated using Garners card sorting method into schizophrenic and depressive patients. The comparison of three performance indices (redundancy, filltering, scanning) between two study groups revealed that 1) the analysis of variance of the corrected time shows no significant difference between two groups, 2) in redundancy and filtering sorting the subtractive and ratio indices show no significant difference between two groups, 3) in scanning sorting the depressive group shows significantly longer sorting time than schizophrenic group(p<0.01 in subtractive index, p>0.05 in ratio index). The above findings suggest that the previously known perceptual deficit(mainly filtering deficit) may not be specific only to schizophrenia.

지역사회 정신의학 전공의 교육과정 실태조사

홍진표,황순찬,이영문,이선형,신나리,이종일,박종익,장동원,정인원 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.1

Objectives : There is a increasing need to recruit and retain more psychiatrists who can plan and implement organized programs to work with chronic mentally ill patients in community settings. The aim of study is to discover what training is currently in place to prepare psychiatrist for work in "community" or "public" settings. Methods : Survey questionnaires were mailed to 85 residency training directors and 10 leaders of community mental health in 2005. Response rate was 75%. Results : Academic seminar about community mental health were not administered to residents in 63% of training hospitals. Forty one out of 64 training hospitals had community mental health rotation programs, Community mental health center (50%) and day hospital (36%) were the most common type of programs. Few general hospital had affiliation with community mental health programs. The amount of time for clinical rotation varied from less than three months part time to 6 months fulltime, with most frequent form of one day per week for three month in second or third year of psychiatry residents. Conclusion : Further steps are needed to improve residency training curricula and to encourage well qualified psychiatrist to choose careers in community psychiatry.

肝吸蟲感染에 있어서의 免疫反應에 關한 硏究 : 白鼠脾藏 大好파이로 닌細胞數의 경시적 變動 Chronological Changes of Large Pyroninophilic Cell Count in the Spleen

李純炯,宋哲鏞 중앙대학교 의과대학 의과학연구소 1978 中央醫大誌 Vol.3 No.1

In order to know some aspects of immune response of albino rats by Clonorchis sinensis infections, the histopathological changes of the liver and the chronological changes of large pyroninophilic cell(LPC) count in the spleen were observed. Rats of 5 experimental groups (A series), each group consisted of 5 rats, were infected with 50 metacercariae of C. sinensis, and they were kept for 3 days (Group Ⅰ), 7 days (Group Ⅱ), 28 days (Group Ⅲ), 56 days (Group Ⅳ) and 84 days (Group Ⅴ). The same number of experimental groups(B series), each group of rats inoculated with 50 adult worms of C. sinensis intraperitoneally, were also kept as same as the above A series. Rats of each experimental groups were sacrificed immediately after the respective infection period, and then microscopic specimens of the liver and spleen were prepared by staining the paraffin sections of removed tissues with hematoxylin-eosin stain and methyl green-pyronin stain. Those materials from the experimental groups were examined in comparison with the materials obtained from non-infected control groups. The results obtained were as follows: 1. The counts of LPC in the periarterial lymphatic sheath of spleen were rapidly increased and reached at the maximum on the 3rd day (Group Ⅰ) in both A and B series of rats. Thereafter, the LPC counts were gradually decreased. 2. LPC counts of A series of experimental group were generally higher than those of B series throughout the whole infection period. 3. Histopathologically the liver failed to show any parasitic worm inside the intrahepatic biliary system in the rats of B series. However, various pathological changes of the liver, which seemed to be induced by the toxic metabolites of C. sinensis inhabiting in the abdominal cavity, were observed in B series of rats.

肝吸蟲에 있어서의 ^14C-glycine을 利用한 自記放射法的 硏究

李純炯,宋哲鏞 중앙대학교 의과대학 의과학연구소 1977 中央醫大誌 Vol.2 No.1

In order to know an aspect of protein metabolism in chinese liverfluke, Clonorchis sinensis, an autoradiographic study was performed. A batch of 25ml Erlenmeyer flasks, each flask containing 10 worms of C. sinensis and 10ml of Tyrode medium with 2.5μ Ci/ml of ^14C-glycine, was incubated for 1 hour in Dubnoff metabolic shaking incubator at 37℃. Those worms were processed for microautoradiography immediately after the incubation, and following results were obtained from the autoradiographs. 1. The densities of black silver grains derived from ^14C-glycine were the most apparent in the subparenchymal cells, intestinal epithelium, vitelline gland cells, ovary and the wall of the seminal vesicle. 2. Moderate grade of densities were observed in the tegument, oral sucker, pharynx, intestinal content and in the testes. 3. The reticular tissue, ventral sucker, uterus with eggs, Seminal receptacle and the content of seminal vesicle showed trace amount of silver grains.

요꼬가와吸蟲症 治療에 있어서 Praziquantel(Distocide^(�))의 效果

李純炯,蔡鐘一,洪性琮,全英淑,徐丙卨 대한화학요법학회 1984 대한화학요법학회지 Vol.2 No.2

國産 praziquantel(Distocide^(ⓡ))의 요꼬가와吸蟲感染에 대한 治療效果를 알아보기 위하여 전라남도 강진군 탐진강 流域의 住民 중에서 68名의 蟲卵陽性者를 색출하고 體重당 100㎎/㎏의 praziquantel을 單回 투여한 후 70일에 追跡大使檢査를 실시하여 驅蟲效果를 判定하였다. 結果는 다음과 같다. 1. 총 45名의 追跡檢査者 중 41名이 蟲卵陰轉되어 91.1%의 治療率(care rate)을 보였으며 이들의 投藥前 E.P.G 合計가 125,600이었던 것이 投藥後 800으로 減少되어 99.4%의 蟲卵率을 보였다. 2. 驅蟲效果는 投藥前 感染强度(E.P.G)에 따라 다소 다른 것으로 나타났으며 輕感染者일수록 높은 效果를 보였다. 3. 藥劑服用에 의한 副作用은 2例에서 가벼운 頭痛이나 현기증을 호소한 이외에는 전혀 문제되지 않았다. 이상의 結果로 볼 때 國産 praziquantel(Distocide^(ⓡ)) 요꼬가와吸蟲症에 대하여 10㎎/㎏ 單回投與로 매우 우수한 驅蟲效果를 보이는 것이 立證되었고 效果, 投藥法, 副作用 등을 감안할 때 집단치료 약제로서 손색이 없을 것으로 생각되었다. Fraziquantel(Cistocide", Chinpoc:-g Pharm. Co). a 'croad spectrum anthelmintic zgzirs: tremato6es and cestodes, ~ 5 - i - a ~ tested for its efficacy In treatment of A!letclgonin.zis yok~govias infection. during the priod fron? Jzmsry t o Ajmi. 1984. A total of 68 egg ~ o s i t i r e cases TTES selected from the inhabitants of Kangjin-gun, South Choila Do, 2nd treated a i t h lOmg/kg ?x<:- weight of I;raziquar.te! in single dose. Among them 25 heavy infection cases were purged ~ i t l 20-20g of magnesium sulfzte(MIgS04) one hour after the treatrcent. Follow up stool exammztion was done after 70 days and the drug efficacy was estimated in terms of cure(=egg negati7-e conversion) and egg reduction rates. The results were as follows: 1. AIiong 45 follm- up cases 41 were cured(91.1% in cure rate) and the pre-treatment E.P. G.(eggs per gram of feces). 125,600, was reduced to 800 after the treatment(gg.4X in egg reduction rate). 2. The cure rates x-ere dependent upon the degiee of E.P.G.; the lower the intensity of infection before treatment, the higher the cure rate was obtained. 3. There x-ere nearly no side effects due t o drug administration except f o r slight degree of headache and dizziness in 2 cases. From these results, it is concluded that lOmg/kg single dose of praziquantel (Distocide") is highly recommendable in treatment of M. gokogawat infection.

肝吸蟲成蟲의 白鼠 腹腔內 注入에 關한 實驗的 硏究

李純炯 중앙대학교 의과대학 의과학연구소 1979 中央醫大誌 Vol.4 No.1

The present experimental study was undertaken to observe the chronological changes of the pathological findings of the liver when fifty adult worms of Clonorchis sinensis were inoculated to each rat intraperitoneally. The pathological changes of the liver were investigated by conventional microscopy in the 5 groups, each group consisted of 5 rats, classified by the duration of observation period, i. e., 4, 10, 28, 56 and 180 days. The results obtained were summarized as follows. 1. Histopatologically the liver failed to show any parasitic worm inside the intrahepatic biliary system. However, multiple well formed egg-containing granulomas were present along the liver capsule. The worms recovered on the surface of the liver capsule were degenerated and necrotized. 2. Portal widening and focal phlebitis together with vascular dilatation were most common features seen in the liver. Occasionally, focal necrosis was also observed. 3. The bile duct in the liver showed mild dilatation of the lumen, epithelial of lining epithelium and periductal small round cell infiltration. Neither adenomatous hyperplasia nor portal fibrosis was seen in the whole experimental group.

폐폴리우레탄 폼을 이용한 유출유 흡수 : Oil, oil/water, 인공해수조에서의 흡유 특성 분석 Estimate of Sorption Properties in Oil, Oil/water, Artificial Seawater

이현구,이춘부,김형순 한국공업화학회 2003 응용화학 Vol.7 No.2

This study investigates the effectiveness of rigid, semi-rigid, and flexible waste polyurethane foams for oil spills clean up. For the three types of the waste foams used as a sorbent, rigid sandwich panel foam, head rest and high-resiliency seat foam in automotive applications were selected, respectively. And the foam of each type also was synthesized with the recipe based on it. The sorption test of the above foams were performed in different types of petroleum products, diesel, bunker-A, and-C, as a function of temperature, and in the presence and absence of water as well. Reuse-ability of the foam were confirmed through measuring for the change of maximum sorption capacity according to sorption cycles. Finally, the same experiments were carried out in artificial seawater bath in order to estimate that actual sorption properties in the sea.

우리나라 인플레의 假說과 그 檢證에 관한 考察

李亨純 成均館大學校 韓國産業硏究所 1974 韓國經濟 Vol.2 No.-

地域社會學校의 部落開發 活動類型및 그 合理的 推進過程에 관한 調査硏究

李淳珩 제주대학교 1982 논문집 Vol.14 No.1

This writing attempts to establish the general task and to grove for the effective method of school activities in the community, which are necessary for the community development. In pursuit of this aim, the writer has considered several types and has made an attempt to find out the reasonable courses of the school function for the villiage development. For the very survey, there were a case study on variable activities of the community school and an use of the questionaire on schools in Jeiu Area. The unit of the community development is made on the basis of a farm villiage centered around a school. And the whole phenomenon of the community is studied throughout the aspects: economy, politic, culture. There are prescrived six areas of community school activities to find a solution to educational problems occured from the said aspects. It is assumed that the school as a main institution for the community development has tried to invest the intended processes in the community as follows: discovering the problems, setting up the improving goals, designing the evaluation criteria, and finding out the proposals and implementaries and the evaluation. It is the assumption that the variety from the said operation means the very function of the school for the villiage development. As a result of the survey, the pattrens of school activities are abstracted as follows: the development of inhabitants' way of thinking and the improvement of their life-style, the spread of the technical side in the farming subsidiary industry for the increase of the income and the support of their industrial activities, the operation of the curriculum centered on the community, the reform movement of the educational environment, and the selfsupport education of the school. It is thus that there can be extracted five types in the school activites. And then the five can be classified into twenty-five details. And as for the unfolding process of the school for the villiage development, it canbe analyzed into two parts: the designing process and the operating one. The former is investigated and commented on the school system and the proper factors of the programs for the fulfillment and forwarding of fhe designed task. In consequence of that, it is approved that the school has made a spread of several activities for the community development, however, the effect leaves an unsatisfied something to be desired. The reason is that there are Ho good operating systems to fulfill the designed programs effectively in the school. Even if the school has them, they are not linked to inhabitants. it is also pointed out that teachers have a weak knowledge and understanding of the programs. From the result of the above survey, the writer likes to make some suggestions for the effective fulfillment of the school program for the villiage development. The first step to take is that the systematical training program fur teachers have to be preceded. And then it is necessary that the school find out the school system emphasized on being linked to inhabitants for another thing.