혈액 투석 환자에서 중심정맥 협착에 대한 스텐트 삽입술 : Wallstent Placement

임대승,노상필,이유선,정승현,김보영,이정우,강정아,김정희,이민수,정준용,최시완,정진옥,성인환,이강욱,신영태 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

Stenosis of central vein is a common complication arising after percutaneous subclavian vein catheter insertion performed for temporary vascular access in chronic renal failure patients undergoing hemodialysis. There are several treatment methods for the condition like percutaneous angioplasty(PTA), stent insertion, and surgery, but recent trend is toward PTA and stents. Among the patients diagnosed with chronic renal failure from March 1993 to May 2002 and undergoing hemodialysis through AV fistula, the 14 Patients in whom central vein stenosis arose were selected for the study. A total of 28 percutaneous interventions(5 PTA and 23 stent placement) were performed, and restenosis rate and the time taken till the restenosis in de novo lesions and instant lesions were compared. All 28 cases were operated successfully. The 14 cases that received both anigioplasty and stent placement initially. (de novo lesion : 14 cases), Among the 10 cases with de novo lesion that followed up more than 1 year, 3 cases are currently undergoing hemodialysis without restenosis, and the remaining 7 cases have recurred stenosis with the mean time to restenosis of 10.9 months. In the 7 cases in whom stenosis recurred, 11 interventions were done(instent lesion: 11 cases). 4 of these were using only ballon angioplasty with 100% restenosis rate and the mean time of 3 months until restenosis. The remaining 7 cases were using both balloon angioplasty and stent placement, also with 100% restenosis rate but with the mean time of 12 months until restenosis, which was later than the group receiving only balloon angioplasty. In treating the patients with central vein stenosis, stent placement seems to be more advantageous over PTA in terms of restenosis rate and the mean duration of patency. In the case of instent lesion, inserting the stent for the second time after stenosis recurred lengthened the duration of patency compared to performing balloon angioplasty alone.

참동계고이의 편찬과 구조

이대승(Lee Dae-seung) 한림대학교 태동고전연구소 2013 泰東古典硏究 Vol.30 No.-

본 글은 주희의 참동계고이에 대한 연구이다. 본 글에서는 심도 있는 참 동계고이 연구를 위한 토대작업으로서 참동계고이의 집필시기와 편찬과 정, 참동계고이의 판본, 그리고 그 구조를 다루었다. 주희는 1186년(57세) 즈음부터 참동계에 이미 관심을 갖고 있었다. 그는 채원정과 함께 1196년부터 집필 작업을 시작하여, 1197년 말엽과 1198년 초엽 사이에 채원정의 아들 채연으로 하여금 1차 간행본을 출판케 한다. 그리고 주희는 이후 수정작업을 거쳐 1199년 봄에 정본을 간행한다. 주희 당시 간행된 채연본은 현재 통행되지 않으며, 현행본은 원대 황서절이 편집한 것으로서 경문과 주석의 문자에서 채연본과 약간의 차이가 있는 것으로 보인다. 주희의 참동계고이는 팽효의 참동계분장통진의를 바탕으로 다른 참동계 판본 들과의 비교·대조 작업을 거쳐 저술된 것으로, 그 구조는 다른 참동계 판본과 큰 틀에서 유사하다. This thesis is a foundation research for an in-depth study for Chantong qi kaoyi (參同契考異) of Zhu Xi and aims to examine the publication and structure of Chantong qi kaoyi. Zhu Xi was already interested in Zhouyi cantong qi (周易參同契) by 1186, his 57 years of age. He started to write Chantong qi kaoyi through a cooperation with Cai Yuanding (蔡元定) in 1196 and made Cai Yuan (蔡淵) publish the first version of Chantong qi kaoyi between end of 1197 and beginning of 1198. He published the formal edition of Chantong qi kaoyi in the spring of 1199 through an amending work with Cai Yuan. The edition of Cai Yuan does not pass on these days, and the current edition is the edition of Huang Ruijie (黃瑞節) on Yuan (元) dynasty, which is a little bit different with the edition of Cai Yuan. Chantong qi kaoyi was made by the comparative study with other Zhouyi cantong qi editions on the basis of Cantong qi fenzhang tong zhenyi (參同契分章通眞義) of Peng Xiao (彭曉). The structure of Chantong qi kaoyi is generally similar with the other editions of Zhouyi cantong qi.

만성 승모판 패쇄부전증 환자에서의 안지오텐신 전환효소 억제제의 장기 투여 효과

김대희,이명묵,이해영,조현재,박승정,서재빈,서정원,양한모,윤창환,조상호,이준희,김용진,김명아,손대원,오병희,박영배 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

Production and Characterization of a Thermo-alkalotolerant Cyclodextrin Glucanotransferase from Thermo-alkalophilic Bacillus cereus B-13

Seo, Seung-Bo,Kim, Jae-Ho,Lee, Dae-Hyoung,Lee, Jong-Soo 배재대학교 자연과학연구소 2005 自然科學論文集 Vol.16 No.1

내열성의 cyclomaltodextrin glucanotransferase (CGTase)를 이용하여 열에 안정한 싸이클린 텍스트린 (CD)을 생산하기 위하여 매우 높은 CGTase 활성을 보이는 고열성이며 호알카리성인 B-13 세균을 분리하여 형태적, 생리학적 특성과 16S 리보솜 RNA 서열분석 등을 통하여 Bacillus cereus B-13으로 동정하였다. Bacillus cereus B-13을 2% 가용성 전분, 1% 효모 추출물, 1% Na_(2)CO_(3) 등을 함유하는 SYC 배지 (pH 8.5)에 접종하여 50℃에서 24시간 배양하였을 때 최고의 CGTase 활성(130 U/ml)을 보였다. 또한 부분 정제된 CGTase의 작용 최적 온도와 pH는 각각 65℃, pH 8.5-9.0 이었고 80℃이하와 pH 5.0-10.0에서 안정하였다. 1% 가용성 전분을 부분 정제한 CGTase와 작용 시켰을 때 49%의 CD 수율을 보였다. To produce a thermostable cyclodextrin by using thermotolerant cyclomaltodextrin glucanotransferase(CGTase), a thermophilic and alkalophilic bacterium isolate, designated B-13 showing the highest CGTase activity was isolated from natural sources and identified as Bacillus cereus B-13 based on the morphological and physiological characteristics, and 16S rRNA sequence. The maximal CGTase activity (130 U/ml) was obtained when Bacillus cereus B-13 was cultured in SYC medium containing 2.0% soluble starch, 1.0% yeast extracts, 1% corn steep liquor and 1% Na_(2)CO_(3) (pH 8.5) at 50℃ for 24 h and about 80% of maximal activity was also showed in the culture broth of 60℃ for 18 h . Optimum reaction temperature and pH of the partial purified CGTase for soluble starch were 65℃ and pH 8.5-9.0, respectively. The partial purified CGTase were also stable below 80℃ and pH 5.0-10.0. When 1% soluble starch was digested with the partial purified CGTase, the yield of cyclodextrin was 49%.

악성 림프종 환자에서 발생한 다형홍반

여운철,조광현,이유신,허대석,이승철 ( Un Cheol Yeo,Kwang Hyun Cho,Yoo Shin Lee,Dae Seog Heo,Seung Chul Lee ) 대한피부과학회 1990 대한피부과학회지 Vol.28 No.5

A Case of Erythema Multiforme A ssociated with Malignant Lymphoma Un Cheol Yeo, M.D., Kwang Hyun Cho, M.D., Yoo Shin Lee, M.D., Dae Seog Heo*, M.D., Seoung Chul Lee**, M.D Department of Dermatology and Internal Medicine*, College of Medicine, Seoul National University, Seoul, Korea, Department of Dermatology**, College of Medicine, Inha University, Kyung Gi Do, Korea We report a case of erythema multiforme associated with malignant lymphoma. Fifty-six-year-old male patient visited our clinic complaining generalized skin lesions which were compatible with erythema multiforme clinically and histopathologically. The skin lesions were treatment-resistant, recurrent and persistent for 3 years. In consideration of old age, atypical features of erythema multiforme and no other demonstrable etiology of erythema multiforme, we studied for internal malignancy. Malignant lymphoma at the duodenum was revealed by UGI series, abdominal CT, and endoscopic biopsy. After chemotherapy, the tumor mass and active skin lesions were cleared simultaneously. Erythema multiforme may be regarded as one of the paraneoplastic syndromes.

점탄성 적층보의 동적 특성 평가와 굽힘진동 감쇠를 위한 최적설계

이민우,김사수,조대승,정상민 釜山大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.53 No.-

감쇠가 적은 금속 구조물의 공진에 의한 진동과 소음을 제어하기 위해 고무, 아스팔트 계열 등의 점탄성 물질이 다양하게 사용되고 있다. 일반적으로 점탄성재료를 이용한 감쇠처리는 점탄성재료의 하부를 모재인 금속층에 취부하고 점탄성재료의 상부를 구속층을 적층하는 방법을 적용한다. 구속감쇠층이 취부된 구조물의 감쇠 및 강성 특성은 온도와 주파수뿐만 아니라 각 층의 두께에 따라 크게 달라진다. 따라서 적은 비용으로 감쇠처리 효과를 극대화하기 위해서는 점탄성층과 구속층 두께의 최적설계가 매우 중요하다. 본 연구에서는 구속감쇠층을 가진 보의 점탄성층과 구속층의 두께 변화에 따른 손실계수의 변화를 면밀히 검토하고, 이를 토대로 지정된 손실계수를 가지되 감쇠층과 구속층의 최소두께를 결정하는 방법을 제시하였다. 제시된 방법의 타당성은 수치실험적 방법으로 검증하였다. For the control of vibration and noise of metal structures having relatively low damping, viscoelastic materials are widely used and usually attached at metal structures with an additional constraining layer to secure them. The damping and elastic properties of structures having constrained viscoelastic material layers are dependent on not only temperature and frequency but also their thicknesses. Hence, optimal design of the thicknesses of viscoelastic and constraining layers for a certain base structure are very important to maximize their efficiency with minimum cost. In this study, the variation of loss factor of beams having a constrained viscoelastic layer according to the change of thickness has been carefully investigated. From these, optimal design method of the minimum thickness beam having a given loss factor is suggested and numerically verified for a real beam.

위암 환자의 복강내 투여를 위한 Activated Charcoal-Alginate Bead 제형으로부터 Mitomycin C의 용출 거동

이진호,최선웅,서중기,김동민,정경수,오정연,김진향,노승무,민병무,김용백,김창식,박근성,강대영,송규상,양준묵,조준식,정현용,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherapy seems a logical choice for cancer chemotherapy. In this study, Mitomycin C (MMC)-activated charcoal (CH)-alginate (ALG) beads were prepared by the mixtures of CH particles adsorbed with MMC as an anti-cancer drug and aqueous alginate solution. The alginate is recognized as biodegradable, nontoxic, and biocompatible. The release of MMC from the beads in 0.1 M Tris buffer was stable and continuous until about 1 week. The MMC-CH-ALG beads can be applied in the peritoneal cavity for intraperitoneal chemotherapy since they provide a good adhesiveness on the tissue and controlled release pattern of the drugs.

소뇌뇌교각종양에서 수술중 전기생리학적 신경계집중감시의 변화

서대원,박관,안재영,이상구,정진상,홍승봉,이원용,김병준,김종현 대한신경과학회 1999 대한신경과학회지 Vol.17 No.1

본딩 와이어의 특성 파라미터 추출에 관한 연구

이승대 남서울대학교 2005 남서울대학교 논문집 Vol.11 No.1

The characteristics of a bonding wire which is widely used in interconnection bare chip or bare die to the substrate is studied. The ohmic resistance is calculated using the phenomenological loss equivalence(PEM) method. In addition, input impedance according to the structure of bonding wire is obtained using the method of moment. The inductance, the capacitance and the characteristics parameters of a bonding pad interconnection bonding wire are calculated.

W-CDMA 용 광대역 BPF의 설계 및 제작

이승대 남서울대학교 공학연구센터 2003 공학연구 Vol.4 No.-

In this paper, achieves minimization for dimension and insertion loss of cavity resonator by reduced order of the cavity using notch pole. This band-pass filter(BPF) is designed and fabricated for center frequency of 2.14 GHz and bandwidth of 18.84 MHz. From the results, the wideband BPF has insertion loss of -1.54dB and attenuation coefficient of less than -l5dB.