Digital infrared thermal imaging in osteoporosis

Lee, Kyung-Sub,Kim, Yong-Suk INSTITUTE OF ORIENTAL MEDICINE KYUNG-HEE UNIVERSIT 2000 JOURNAL OF ORIENTAL MEDICINE Vol.5 No.1

This study examined the relationship between bone mineral density and DITI in the diagnosis of osteoporosis. An analysis was performed on the thermographic findings of 20 patients without osteoporosis, 20 with osteopenia and 20 with osteoporosis at the Kangnan Korean Hospital, Kyung-Hee University, Seoul, Koera, from June 1998 to February 1999. The osteoporosis was measured by LUNAR PIXI and the body temperature was assessed by DITI. Thermogrphic measurements were performed on 4 areas(acupuncture point: CV12, CV4, BL23 and BL26). All data were coded for computer analysis and significances were tested by Duncan test. There was no significant diference in age among the three groups of patients. DITI revealed the significant hypothermia (p<0.001) on the osteoporosis patients compared with osteopenia and normal bone density patients. It is believed tha DITI may be a favorable alternative to diagnosis of osteoporosis.

바른체형운동 지도가 정신장애인의 우울감 및 폐활량에 미치는 효과

우경희(Kyung-Hee Woo),양정옥(Jeong-Ok Yang),이중숙(Joong-Sook Lee),이범진(Bom-Jin Lee),김의숙(Eui-Suk Kim),정숙희(Sook-Hee Jung),곽이섭(Yi-Sub Kwak) 한국생명과학회 2016 생명과학회지 Vol.26 No.10

본 연구는 바른체형운동 프로그램이 정신장애인의 폐활량 및 우울감에 미치는 영향을 알아보고자 경북 P시에 거주하고 정신장애 판정을 받았으며 정신재활프로그램에 참여하는 정신장애인을 대상으로 실시하였다. 참여한 피험자에게 연구목적과 내용을 설명하였고, 연구 참가동의서를 받은 19명을 최종 선정하여 10명은 운동군, 9명은 통제군으로 분류하여 12주간 바른체형운동 프로그램을 실시하였고, 연구결과는 다음과 같다. 우선 폐활량의 변화를 살펴본 결과 PEF (최대호기속도)와 FEV1/FVC (1초간 노력성 호기량의 노력성 폐활량에 대한 비)가 바른체형운동 적용 후에 증가하여 호기기능이 유의하게 향상됨을 확인하였다. 또한, 바른체형운동 프로그램 참여에 따른 운동군의 우울감의 변화는 통계적으로 유의한 차이는 나타나지 않았으나 우울정도의 감소폭이 통제군보다 운동군에서 훨씬 크게 나타나 바른체형운동이 정신장애인의 우울감 정도의 감소에 긍정적인 변화를 나타냈다고 할 수 있다. 그리고 본 연구에서는 프로그램 참가자들의 특수성으로 인한 표본 수의 한계로 인해 통계적 검증의 한계가 명확히 존재함을 고려하여 참여자들의 주관적 경험을 심층적으로 이해하는 것을 목적으로 한 질적분석(qualitative research)을 병행하여 실시하였다. 프로그램 참가자 중 동의하는 사람에 한해 심층적 면담을 실시하였으며 이를 통해 참여자들이 표현하는 내용의 의미단위를 검토하여 분류하고 세분화하는 작업을 통해 주제분석(thematic analysis)을 실시한 결과, 전반적으로 바른체형운동 프로그램에 참여한 정신장애인들의 우울감 정도가 줄어든 것을 알 수 있었다. 우울감의 변화과정은 ‘변화의 시작’, ‘프로그램에 대한 흥미’, ‘신체적 건강의 필요성에 대한 인식’, ’신체적 건강증진’, ’신체적 기능의 회복’, ’부정적인 습관(자세)의 변화’, ’우울감의 감소’, ’할 수 있다는 자신감’, ’미래에 대한 희망’과 같은 3개의 주제와 6개의 하위 주제로 나타났다. 따라서 바른체형운동이 정신장애인들의 신체적 건강증진을 위해 심폐지구력을 높여 신체적 건강증진을 도모할 뿐 아니라 더 나아가 정신적 우울감의 감소에도 효과성을 높여 정신적 건강증진에도 도움을 줄 수 있는 프로그램으로 정신장애인의 삶의 질 증진을 위해서는 보급이 반드시 필요할 것으로 사료된다. The purpose of this study was to investigate the effects of the regular Upright Body Type Excercise on posture, muscle strength of leg, lung capacity and depression of people with mental illness. The subjects of this study were recruited from B mental health center (5 years and more mental illness patients, n=19) located in P city. For the exercise group, They were carried out the Upright Body Type Excercise Program during 8 weeks (60 min/time, 3 times/week). They were randomly divided into two groups. Exercise group (n=10) and Control group (n=9). And also, they were agreed with consent forms before the experiments. Research results were as follows. Through the upper body type exercise, there was significantly difference in PEF and FEV1/FVC in the trained group. And also, there was much improved in depression level in the trained group. The change of melancholy feeling before and after the program was not statistically significant. However, because of limitations of sampling size due to the peculiarities of the program participants, in consideration of the limit of statistical validation exists clearly, intended to better understand the subjective experience of attendees, qualitative analyzing(qualitative research) was carried out in parallel. It was conducted a deep interview only person accepted among program participants, thematic analysis, subject analysis tasks to be subdivided by classifying by considering the semantic units of what participants expressed, was thus carried out. It found that the degree of melancholy feeling of mental disorders who participated in the Upright Body Typed Exercise Program was reduced. The course of the experience of change in depression appered the three subjects and six sub-themes such as “the start of the change”, “interest of the program”, “recognition of the need of the body`s health”, “physical health promotion”, “recovery of physical function”, “negative change of habits (attitude)”, “reduction of sense of depression”, “confidence that it is possible to”, “hope for the future”. Therefore, upper body type exercise is much helpful in lung capacity and mental health of people with mental illness. So, this type of exercise mostly needed in the people with mental illness group than the other group for the quality of life.

Clinical Manifestations and Treatment Outcomes of Eosinophilic Gastroenteritis in Children

Jong Sub Choi,Shin Jie Choi,Kyung Jae Lee,Ahlee Kim,Jung Kyung Yoo,양혜란,문진수,장주영,고재성,강경훈 대한소아소화기영양학회 2015 Pediatric gastroenterology, hepatology & nutrition Vol.18 No.4

Purpose: The aim of the present study was to investigate the clinical features and outcome of eosinophilic gastro-enteritis (EGE) in children.Methods: Our study enrolled 24 children who were diagnosed with EGE from 1993 to 2014 at the Department of Pediatrics, Seoul National University Children’s Hospital. The patients’ clinical manifestations, treatments, and out-comes were reviewed from the medical records.Results: The mean age at diagnosis was 5.3 years. Most patients had gastrointestinal symptoms including diarrhea (54.2%) and abdominal pain (45.8%). Peripheral eosinophilia was present in 91.7% of the patients. Thirteen patients (54.2%) showed anemia, and 15 patients (62.5%) had hypoalbuminemia. EGE was classified as mucosal, sub-serosal, or muscular in 75.0%, 20.8%, and 4.2% of cases, respectively. Three patients showed gastroduodenal ulcers upon endoscopic analysis. A history of allergy was reported in 13 patients, including atopic dermatitis, allergic rhinitis, and asthma. Five patients (20.8%) improved with food restrictions. Among the 19 patients treated with steroids, 11 (57.9%) discontinued steroid treatment without subsequent relapse, 4 (21.1%) relapsed after ceasing steroid treat-ment, and 4 (21.1%) showed no response to steroids. Two patients who were resistant to steroids underwent ther-apeutic surgery. The presence of gastroduodenal ulcers was significantly associated with relapse and steroid resistance.Conclusion: A high suspicion of EGE is warranted when children have nonspecific gastrointestinal symptoms and peripheral eosinophilia. Most patients improved with food restrictions or steroid treatment, although one-third of pa-tients showed a relapse or steroid resistance.

Purge & Trap-GC를 이용한 의약품 필름코팅 정제 중 잔류용제에 관한 연구

장준식,이명자,소유섭,문춘선,이주헌,박희라,김진숙,강경모,이선옥,방성연,유미자,유문균,금오성,이병욱 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-

의약품은 약물을 생체에 적풋하기 위하여 유효성분의 효과가 언제나 일정하게 확보되고 사응에 편리하도록 만들어지는 것이므로 유효썽분 이외에 약효에 영향을 주지 않는 성분이 첨가되는 경운가 많다. 이 때 사용되는 용매들은 제피의 광택 및 건쪼시간의 단축 등을 위하여 휘발점이 낮을 용매들이 주로 사용되어진다. 본 연구는 의약품 필름코팅정제 중 잔류용매 4종(chlorofonr benzen, trichloro ethylen, 1,4-dioxane)에 대한 변형된 pirge & trap-GC 장치를 이용한 동시분석방법을 개발하였으며, 각 표준품의 RSD 값은 chloroform 3.03%, benzen 3.17%, trichloroethylen 3.69% and 1,4-dioxane 3.41%였다. 또한 시중 유통중인 의약품 50종에 대하여 잔류웅매 양을 측정하였으며, 검출되는 잔류용매는 한 건도 없었다. This study nras carried out to develope the analytical method for the mixture of chlorefonn, benzen, trichloroethylen and 1,4-dioxane simultaneously and determine the remainingorgauic solvents in coating tablets by Purge & Trap-GC. The results were as follouFs ; 1. Chloroform, benzen, trio:tloroethylen and 1,4-dioxane separated by tenax #5 trap by HP-624GC column by terrlperature programming. The peaks were separated completely at retentiontime of 6.88min for chloroform, 8.21min for benzen, 10.38miu for trichloroethylen and 11.95minfor 1,4-dioxane. 2. Standard RSD were individually chloroform 3.03%, benzen 3.17%, trichloroethylen 3.69%and 1,4-diorane 3.41%. 3. 60 samples were not detrcted chloroform, benzen, trichloroethylen and 1,4-dioxane.

High-throughput screening of protein variations in soybean seeds.

Vijayanand Velusamy,Kyung Jun Lee,Bo-Keun Ha,Jin Baek Kim,Sang Hoon Kim,Si-Yong Kang,Dong Sub Kim 한국육종학회 2012 한국육종학회 심포지엄 Vol.2012 No.07

The protein in soybean seeds accounts for approximately 40% of the dry seed weight. Two major storage proteins, 7S and 11S, constitute 70-80% of the total storage proteins in the seeds. In this study, the variation of total soluble protein extracts from 1152 soybean landraces that have been collected from South Korea were studied using high-throughput screening method with HT Protein Express Labchip (Caliper Life Sciences, Inc.). Seven distinct protein band patterns - four protein sub-units of 11S and three sub-units of 7S, were taken into account and their presence or absence were analyzed. Among the 1152 landraces, 525 genotypes were identified as lacking lipoxygenase, 255 lacking α1 subunit, 680 lacking α subunit, 169 lacking β subunit, 140 lacking acidic, 114 lacking Kunitz Trypsin Inhibitor (KTi) and 199 lacking basic protein patterns. The high-throughput protein analysis is helpful in screening a large number of populations with less time and minimum labor. The selected genotypes with low amounts or lacking of anti-nutritional factors such as trypsin inhibitor, lipoxygenase and α subunit would be used for future breeding purpose of quality improvement in soybean protein.

강남경희한방병원에 내원한 냉증을 호소하는 여성의 Heart Rate Variability 특성 연구

이미주 ( Mi Joo Lee ),김은경 ( Eun Kyung Kim ),이진무 ( Jin Moo Lee ),조정훈 ( Jung Hoon Cho ),장준복 ( Jun Bock Jang ),이경섭 ( Kyung Sub Lee ),이창훈 ( Chang Hoon Lee ) 대한한방부인과학회 2011 大韓韓方婦人科學會誌 Vol.24 No.3

수부냉증이 있는 산모의 체성분학적 특성 분석

이미주,이창훈,이경섭,Lee, Mi-Joo,Lee, Chang-Hoon,Lee, Kyung-Sub 대한한방체열의학회 2011 대한한방체열의학회지 Vol.9 No.1

Purpose :To analyze body composition in postpartum women with cold-hypersensitivity, their edema index, skelectal muscle's weight and body fat were measured and analyzed with cold hypersensitive postpartum women compared with those of non-cold hypersensitivity. Methods : We studied 38 postpartum women visiting Gangnam Kyung-Hee Korean Hospital from 1 st October 2010 to 30th september 2011. they were subjected to Digital Infrared Thermal Imaging and those with thermal difference greater than $0.3^{\circ}C$ between anterior forearm and center of hand were diagnosed with cold hypersensitivity. Cold hypersensitivity group were consisted of 11 women, the other were consisted of 26 women. All of them were measured Edema index, skelectal muscle's weight and body fat by Inbody720(body composition scanner). We studied the difference of Body composition factor between two groups and relationship between cold-hypersensitivity, Edema index, skelectal muscle's weight and body fat by Independent Samples T-test and Spearman Correlation. Results : No significant differences were observed in edema index, skelectal muscle's weight and body fat between two groups. Conclusion : There was no significant relationship among the Cold-hypersensitivity and Body composition factor(Edema index, skelectal muscle's weight. body fat). But furthemore large scale study is required.

부인과질환, 월경통과 여성 체형 및 체온의 상관성 연구

최석영 ( Seok Young Choi ),안지윤 ( Ji Yoon Ahn ),이미주 ( Mi Joo Lee ),이진무 ( Jin Moo Lee ),장준복 ( Jun Bock Jang ),이경섭 ( Kyung Sub Lee ),이창훈 ( Chang Hoon Lee ) 대한한방부인과학회 2012 大韓韓方婦人科學會誌 Vol.25 No.4

Objectives: A women`s body type or body temperature is often thought to be associated with gynecologic disorders or dysmenorrhea. The purpose of this study is to analyse the characteristics of body type and body temperature in relation to gynecologic disorders and dysmenorrhea. Methods: We studied 40 patients visiting Kangnam Kyung-hee Medical Center from Jan. 1st, 2010 to March 31st, 2012. Body type and body temperature were compared between Gynecologic disorder group and non-Gynecologic disorder group. Body type and body temperature were compared again between Dysmenorrhea group and non-Dysmenorrhea group. SPSS 18.0 for Windows was used to analyse the data. Results: There was no statistically significance difference in body type and body temperature between Gynecologic disorder group and non-Gynecologic disorder group. Dysmenorrhea group had more developed lower body and greater temperature difference between lower abdomen and foot compared to non-Dysmenorrhea group. Conclusions: The results suggest that women with developed lower body and greater temperature difference between abdomen and lower extremity are more prone to dysmenorrhea.

향사이중탕가미방(香砂理中湯加味方)으로 전신냉감과 자한 호전된 여환 1례

최석영,이미주,김은경,이창훈,이경섭,Choi, Seok-Young,Lee, Mi-Joo,Kim, Eun-Kyung,Lee, Chang-Hoon,Lee, Kyung-Sub 대한한방체열의학회 2011 대한한방체열의학회지 Vol.9 No.1

Purpose : The purpose of this study is to investigate effect of Hyangsayijoongtang-gamibang on Cold Hypersensitivity and accompanying perspiration. Methods : Hyangsayijoongtang-gamibang was used for a Cold Hypersensitivity patient with accompanying perspiration that was admitted to Kangnam Kyung-Hee Korean Hospital from May 2nd, 2011 to May 14th, 2011. The efficacy of the treatment was evaluated with Digital Infrared Thermal Imaging(DITI). along with objective and subjective observations. Results : After treatments of oriental medicine. the mean body temperature elevated $1.32^{\circ}C$. and the mean temperature difference between different points of the body decreased more than 50%. Subjective observation of Cold Hypersensitivity and accompanying perspiration using Visual Analog Scale(VAS) also showed improvement. Conclusion : Results suggest that Hyangsayijoongtang-gamibang is effective in treating Cold Hypersensitivity patients with accompanying perspiration.

유방 섬유선종이 있는 2, 30대 여성의 HRV 특성 연구

안지윤 ( Ji Yoon Ahn ),최석영 ( Seok Young Choi ),이미주 ( Mi Joo Lee ),이진무 ( Jin Moo Lee ),장준복 ( Jun Bock Jang ),이경섭 ( Kyung Sub Lee ),이창훈 ( Chang Hoon Lee ) 대한한방부인과학회 2012 大韓韓方婦人科學會誌 Vol.25 No.4

Purpose: This study aims to analyze Heart Rate Variability(HRV) in women with fibroadenoma compared with non-fibroadenoma women. Methods: We studied 82 patients visiting Kang-Nam Kyung-Hee Korean Hospital Medical Examination Center from January, 2010 to November, 2011. The subjects were categorized in two groups, fibroadenoma group(n=16) and non-fibroadenoma group (n=66). We investigated the difference of HRV between two groups. Results: The square root of the mean squared difference of successive NNs (RMSSD) in fibroadenoma group is significantly lower than non-fibroadenoma group. LF/HF ratio in fibroadenoma group is significantly higher than non-fibroadenoma group. There was no significant difference in low frequency(LF) and high frequency (HF). However, normalized LF in fibroadenoma group is significantly higher than non-fibroadenoma group. In addition, normalized HF in fibroadenoma group is significantly lower than non-fibroadenoma group. Conclusions: Fibroadenoma group is related to autonomic nerve imbalances that is assumed by psychological problems.