고요산혈증의 위험인자 : 아산시 지역 주민을 대상으로

김용배,장원기,황보영,김화성,안규동,이병국,이용진,이종은,이준숙,이찬구,이한정,이성수 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

Objective : Serum uric acid has now been identified as a marker for a number of metabolic and hemodynamic abnormalities. The aim of this study is to evaluate risk factors which influence hyperuricemia in the citizens of Asan. Method : The study design was cross-sectional and research subjects were 1086 citizens of Asan. General characteristics, cigarette smoking, alcohol consumption, and past history were obtained by interview using a structural questionnaire. Also, we measured height, weight and blood pressure, and serum uric acid of the subjects. Results : The mean serum uric acid level was 5.27 ㎎/㎗ in men and 4.01 ㎎/㎗, in women, In the multiple logistic regression analysis, statically significant risk factors of hyperuhcemia were gender, body mass index, blood lead concentration, and serum creatinine. Conclusion : Our results suggest that gender, body mass index, blood lead concentration, and serum creatinine might be the most important risk factors of hyperurcemia. Education program as well as routine check-up for serum uric acid was highly recommended for the effective prevention of hyperuricemia.

經穴의 艾灸生體反應이 失血性貧血에 미치는 影響

李殷洪,박인규,임종국,김진택 東國大學校韓醫學硏究所 1992 동국한의학연구소 논문집 Vol.1 No.-

In order to observe the effects of moxibustion on anemic condition as a acute loss of blood, white rats were induced loss of blood by cadiac puncture. And then morphologically variation of The Bone Marrow was observed the following points of each rat were used : Shinsu(B23 or Ⅶ23), Hyeonjong(GB39 or XI39), and complex of shinsu(B23 or Ⅶ23) and Hyeon Jong(GB39 or XI39) Comparing these above method with the control group the results were as follow: 1. Moxibustion in Shinsu have an influence on activation of Normoblast and do for hematosis function of bone marrow 2. Formation ability of R·B·C(Red Blood Cell)turn up order a list of Mocibustion in Shinsu(B23 or Ⅶ23), Moxibustion in conplex of Shinsu(B23 or Ⅶ23) and Hyeon Jong(GB39 or XI39), moxibus-tion in Hyeon Jong(GB39 or XI39) 3. Moxibustion in complex of Shinsu(B23 or Ⅶ23) and Hyeon Jong(GB39 or XI39) moderately increase Megakaryocyte

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

日本의 私學評議員會에 관한 硏究

李鍾國 상명대학교 논문집 1990 상명대학교논문집 Vol.26 No.-

Throughout the studying of the private school law and the reference books of Japan, this paper provides the followings, (1) What characteristics does the Board of Councilors of Private School are organized, (3) What's the function and the duty of these council, (4) In addition, through studying What's the way of management of the council, (5) Pointing out the problem with introduction of this council to our country and searching for the solution of it.

건설 의사결정지원용 정보시스템 활용특성모델 제안

이종국 금오공과대학교 2005 論文集 Vol.26 No.-

Many construction companies have developed many kinds of information system to integrate the information created. in the phase of planning, design, procurement, construction, and maintenance of construction project. However, the previous researches for the state of applying information technologies and the efforts of the analysis of the present information system launched. in domestic construction industry is very rare. 1here also has been short of research on the construction decision-making support theory in construction business and industry. Hence this paper would contribute in identifying the state of information technologies and the theory of decision-making support of the information system in general construction company, and propose the characteristic model on the information system for the construction decision-making support. The model consists of the two dimensions; (1) organizational hierarchy (2) data analyzing technology. This research, especially, can be expected. to initiate the discussion on framework for understanding the construction decision-making support system in construction industry. The model is not a practical methodology, but a window that offers a new perspective on sources of information system in each construction company, and thus can provide a clue of the useful guide to construction information system development.

심부전 환자의 중증도의 지표로서 Cardiac Troponin Ⅰ의 임상적 유용성

이현국,배우형,김성호,안병재,전국진,홍택종,조병만,손한철,신영우 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.6

反復演習 類型의 CAI 프로그램 設計 및 具現

이상정,안종근,송제국 순천향대학교 1994 논문집 Vol.17 No.3

The use uf computer in learning has advantage of providing various function of audio-visual education regardless of places, especially it enables us to overcome the limitation of individual learning in traditional instruction. Today a lot of CAI courseware is developed and used. But most of them are limited on only one unit or one subject. Because of their lack of sequence in learning, there are problems of systematic learning and connection among grades. The purpose of this study is to design and develope a drill & practice CAI courseware which is proper to realize sequence among grade and easy to feedback. The results of this study are as follows: 1. After choosing arithmetics of the 5th and 6th grade of elementary school, it is designed and developed a 32 sub-subjects CAI program according to the 17 subjects in 3 units. 2. This program is implemented menu-driven meihod in order to learn total arithmetics learning. It will be completed by a following study or research for unimplemented parts.

C++를 이용한 통신 시뮬레이터의 설계 및 구현

이광휘,정상국,안정희,김한경,이종근 國立 昌原大學校 精報通信硏究所 1998 精報通信論文集 Vol.2 No.-

In this paper, we are designed and implemented communication simulator, for two systems which communicates in peer-to-peer and simulating for protocol, to verify the interwork not yet designed system Peerl and now being operated Peer2. To begin with, after the investigation in Interworking Standard in Interface Control Document and check the satisfied requirements in each system, the environment of simulator is set up. We examine Interworking Standard in FSM representation. And in protocol design, partial steps follows necessary procedure of protocol engineering. Simulator is implemented in C++ and, to interwork two systems smoothly, the whole system will be merged. Finally, a design and implementation of simulator is completed by confirming simulation results of simulator and Interworking Standard coincide.

전자세라믹스 소성용 고알루미나질 내화붕판의 개발

이종국,노희진,배지수 조선대학교 생산기술연구소 2000 生産技術硏究 Vol.22 No.1

High alumina sagger for the sintering of electroceramics contained the superior sintered properties and fracture strength at high temperature was developed by the addition of large fused-mullite particles. High alumina sagger with large fused alumina particles shows many large cracks at interfaces between mullite matrix and large fused-alumina particles, resulting in the low sintered density and fracture strength at high temperature. However, the substitutuion of some large fused-mullite particles for large fused-alumina particles reduced the large cracks between matrix and particles, and also enhanced the sintered properties (apparent density and the percentage of absorption) and the high fracture strength.

산모혈과 제대혈에서 연농도에 관한 조사

이덕희,문종국,배강우,이용환,김진하,박강원 大韓産業醫學會 1996 대한직업환경의학회지 Vol.8 No.3

This study was conducted to evaluate the blood lead levels in 141 pregnant women who were not occupationally exposed to lead and their umbilical cord, and to identify some differences in blood lead levels by living area. The subjects were all delivered at St. Benedict Hospital in Pusan and the blood lead levels were measured by graphite furance atomic absorption spectrophotometer. The summarized results were as follows. 1. The geometric mean lead levels in maternal and cord blood were 8.0±1.8μg/dl, 5.0±0.6μg/dl respectively. 2. Lead levels in maternal(8.7±1.7μg/dl) and cord blood(5.4μ±0.7μg/dl) of industrial area(n=24) were higher than residential area(n=124) which were 7.9±1.7μg/dl and 5.0±0.6μg/dl respectively(p<0.05). 3. Maternal blood lead concentration was significantly correlated to cord blood lead concentration(r=0.6090, p<0.001), but other variables(maternal age, paternal smoking, birth weight, etc) were not correlated.