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석면관련 폐질환의 진단에 있어서 흉부고해상도전산화단층촬영검사(HRCT)의 유용성
이현재,손지언,,홍영습,,이영일,예병진,유창훈,정갑열,김상훈,임형준,장은철,김정만,김준연 大韓産業醫學會 2006 대한직업환경의학회지 Vol.18 No.2
목적: 석면에 노출된 근로자에서 석면관련 폐질환의 양상을 분석하고 진단에 있어 HRCT의 유용성을 연구하여 석면에 대한 의학적 감시프로그램의 개발에 기여하고자 하였다. 방법: 석면에 직접 노출되는 작업자 68명과 간접 노출되는 작업자 94명 등 총 162명에 대해 OSHA 석면 표준, 의학적 감시 프로그램에 따라 단순 흉부방사선검사, 폐활량검사 및 우리나라 실정에 맞게 일부 수정한 의학적 설문지를 통해 면접조사의 방식으로 환자에 관한 정보를 수집하였으며, 자료의 신뢰성을 확보하기 위하여 면접조사는 1달 이상의 기간을 두고 2차례에 걸쳐 실시된 후 확인, 수정하였다. 또한, 석면관련 폐질환을 확진하기 위하여 HRCT를 추가적으로 실시하였다. 결과: HRCT결과 석면관련 폐질환의 유병율은 162명의 근로자중 17명으로 10.5%였는데, 직접 노출군에서 10명 (14.7%), 간접 노출군에서 7명 (7.4%)이었다. HRCT와 비교할 때 단순 흉부방사선검사의 민감도와 특이도는 각각 70.6%와 98.6%이었고, 양성 예측도와 음성 예측도는 각각 85.7%와 96.6%으로, HRCT는 단순흉부방사선검사에 비해 민감도가 높아 초기 석면관련 폐질환을 진단하는데 효과적이었다. 석면관련 폐질환의 진단에 있어 HRCT와 폐활량검사 사이에 유의한 관련성이 관찰되었다. HRCT 결과 석면관련 폐질환의 유무와 의학적 설문조사 결과의 빈도분석을 실시한 결과, 유의한 변수는 작업기간, 흡연량, 호흡기질환의 과거력, 기침, 호흡곤란이었다. 결론: HRCT는 석면관련 폐질환의 진단에 있어 단순 흉부방사선검사와 비교하여 민감도가 높아 초기 진단에 유용하므로 단순 흉부방사선선검사 결과 석면관련 폐질환소견을 보일 때뿐만 아니라, 정상소견을 보이더라도 폐활량 검사결과와 근무력, 흡연력, 호흡기질환의 과거력, 기침, 호흡곤란 등의 호흡기 증상을 참고하여 HRCT검사를 고려해야 한다. 또한, 본 연구에서 관련성이 없었던 요인들에 대해서도 향후 연관성을 규명하는 광범위한 전향적 연구가 필요하다. Objectives: This study was carried out to improve the medical surveillance program of workers exposed to asbestos by examining the usefulness of High Resolution Computed Tomography (HRCT) in the diagnosis of asbestos-related lung disease. Methods: The study subjects comprised 162 workers in a ship-repairing yard, 68 of whom had been directly exposed to asbestos and 94 indirectly exposed. The 'Occupational Safety & Health Administration (OSHA) asbestos standard, medical surveilance program' and HRCT were conducted to analyze the aspects of the asbestos-related lung disease. The OSHA asbestos standard, medical surveilance program consists of simple chest x-ray, spirometry and medical questionnarie. Results: Seventeen (10.5%) of the 162 subjects, 10 (14.7%) directly exposed and 7 (7.4%) indirectly exposed, revealed asbestos-related lung disease on HRCT. The sensitivity and specificity of simple chest x-ray for asbestos-related lung disease were 70.6% and 98.6%, and the positive and negative predictive values were 85.7% and 96.6% respectively, as compared with HRCT, HRCT was an effective diagnostic tool especially to detect early asbestos-related lung disease. The study results indicated a relative significant association between the results of spirometry and HRCT. The variables significantly associated with asbestos-related lung disease on HRCT were work duration, smoking history (pack-years), past history of respiratory disease, cough and dyspnea. Conclusions: In the diagnosis of asbestos-related lung disease, HRCT should be considered not only for workers with positive findings on simple chest x-ray, but also workers with specific findings on spirometry, occupational history, smoking history, and past history of respiratory disease, or with respiratory symptoms such as cough and dyspnea.
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이종상(Jong-Sang Lee),장갑만(Kap-Man Jang),이윤형(Yoon Hyoung Lee),임상식(Sang-Sik Yim),이진한(Jin-Han Lee) 한국가스학회 2014 한국가스학회지 Vol.18 No.6
In this study, it is analyzed that a change in the shape of small propane containers made of STS304 when increasing of internal pressure. When internal pressure of a small propane container increased, bottom of end plate is convexly changed. This test is applied to a water bath pressure test to analyze the characteristics of the container. Water bath is able to analyze relationship between internal pressure and volume. In result, shape change section is confirmed because bottom of end plate is convexly changed. In addition, this section tend to decrease internal pressure because a volume increment increase out of proportion to pressure. The results of this study are expected to contribute to improving the safety of the pressure vessel, as well as various small propane container.
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Han, Kap-Soo,Lee, Sang Hyuk,Ryu, Han Uk,Park, Se-Hyoung,Chung, Gyung-Ho,Cho, Young I.,Jeong, Seul-Ki Hindawi 2017 BioMed research international Vol.2017 No.-
<P>The aim of the study was to calculate the arterial wall signal intensity gradient (SIG) from time-of-flight MR angiography (TOF-MRA) and represent arterial wall shear stress. We developed a new algorithm that uses signal intensity (SI) of a TOF-MRA to directly calculate the signal intensity gradient (SIG). The results from our phantom study showed that the TOF-MRA SIG could be used to distinguish the magnitude of blood flow rate as high (mean SIG ± SD, 2.2 ± 0.4 SI/mm for 12.5 ± 2.3 L/min) and low (0.9 ± 0.3 SI/mm for 8.5 ± 2.6 L/min) in vessels (<I>p</I> < 0.001). Additionally, we found that the TOF-MRA SIG values were highly correlated with various flow rates (<I>β</I> = 0.96, <I>p</I> < 0.001). Remarkably, the correlation coefficient between the WSS obtained from the computational fluid dynamics (CFD) analysis and the TOF-MRA SIG was greater than 0.8 in each section at the carotid artery (<I>p</I> < 0.001 for all <I>β</I> values). This new technique using TOF-MRA could enable the rapid calculation of the TOF-MRA SIG and thereby the WSS. Thus, the TOF-MRA SIG can provide clinicians with an accurate and efficient screening method for making rapid decisions on the risk of vascular disease for a patient in clinical practice.</P>
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200 ㎸ 용량형 분압기 2대를 이용한 교류 고전압 측정범위 확장
鄭在甲(Jae-Kap Jung),李相和(Sang-Hwa Lee),姜銓洪(Jeon-Hong Kang),金明壽(Myung-Soo Kim),金潤亨(Yoon-Hyoung Kim),韓相吉(Sang-Gil Han),鄭辰慧(Jin-Hye Jeong),韓相玉(Sang-Ok Han),鄭鍾萬(Jong-Man Joung) 대한전기학회 2008 전기학회논문지 P Vol.57 No.1
The output voltage value of AC high voltage source has been usually obtained by multiplying low voltage value measured at both terminals of low voltage resistor by the dividing ratio of the high voltage capacitive divider. From the dividing ratio determined of each 200 ㎸ capacitive divider, we have developed step-up method for measuring the output voltage up to 400 ㎸ using two same type of 200 ㎸ capacitive dividers connected in series. The theoretical dividing ratio of 400 ㎸ capacitive dividers connected in series coincides with that of manufacturer's certification within measurement uncertainty. Thus, this developed step-up method makes it possible to extend the range of output voltage from 200 ㎸ to 400 ㎸, Furthermore. The dividing ratio of divider under test obtained using this step-up method is consistent with that obtained using one 200 ㎸ high voltage divider within corresponding uncertainties.
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