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      • 대호 간척기 토양의 염농도별 밭작물의 염해 평가

        이승헌,류순호,설수일,안열,정영상,이상모 江原大學校 附設 環境硏究所 2001 環境硏究 Vol.18 No.-

        This study was carried out to obtain the basic data for selecting the applicable crops in reclaimed land during desalinization period. A pot experiment was conducted with 5 different electrical conductivities of the saturated extracts (ECe 1, 3, 9, 14, and 16 dS·m^(-1)) of soils taken from the Dae-Ho reclaimed tidal lands. Eight crops (Chinese cabbage, radish, tomato, red pepper, buckwheat, soybean, sesame, and green perilla) were grown for 37days. Plant height and number of leaves were surveyed on 2 and 4 weeks after seeding, and on harvest time (5 weeks). After harvest, dry weights of harvested crops were measured and soil chemical properties were analyzed. Emergence rates of crops were comparatively high except sesame. For sesame, there was no emergence at ECe over 3 dS·m^(-1). Growth and dry weight decreased significantly as increasing ECe. The ECe which decreased 50% of dry weight index were 14.2 dS·m^(-1) for radish, 11.4 dS·m^(-1) for Chinese cabbage, 10.2 dS·m^(-1) for tomato for red pepper, 8.9 dS·m^(-1) for buckwheat and green perilla, 8.6 dS·m^(-1) for soybean, and 8.9 dS·m^(-1) for tomato. At higher ECe that start the growth inhibition, increasing 1 dS·m^(-1) in ECe, 7.7, 6.5, 5.9, 5.6, 5.2, and 4.9% of dry weight decreased for buckwheat, green perilla, Chinese cabbage, radish, soybean, and tomato (red pepper), respectively. The critical value of ECe for crop survival except sesame was 15.4~23.1 dS·m^(-1).

      • Two new records of the genus Nola Leach, 1815 (Lepidoptera: Nolidae, Nolinae) from Laos

        Yeong–Bin Cha,Ulziijargal Bayarsaikhan,Sol–Moon Na,Dong–June Lee,Jae–Ho Ko,Tak–Gi Lee,Hyeong–Kyu Kim,Chang–Moon Jang,Han–Ul Kim,Yang–Seop Bae 한국응용곤충학회 2019 한국응용곤충학회 학술대회논문집 Vol.2019 No.04

        The genus Nola (Nolidae, Nolinae) was established by Leach (1815), with the Noctua palliola Denis & Schiffermüller, 1775 (a junior subjective synonym of Phalaena cucullatella Linnaeus, 1758) from Vienna, Austria. Nola comprises over 200 species: Africa and western Palearctic approximately described 100 speices (Hacker et al., 2012); Oriental and Eastern Palearctic regions have over 100 species (László et al., 2010; Sasaki et al., 2011; Kononenko and Pinratana, 2013). Two species of the genus Nola Leach; Nola euryzonata (Hampson, 1900) and Nola lucidalis (Walker, 1865), reported for the first time in Laos. Illustrations of adults and genitalia of all the examined species are provided.

      • KCI등재

        크롬(Ⅵ)의 체내 흡수와 소실속도에 관한 연구

        김현영,이성배,임철홍,이권섭,정용현,이종성,한정희,전윤석,황호순,이용묵 한국산업위생학회 2003 한국산업보건학회지 Vol.13 No.1

        The CrO3 mostly used in plating. metal surface disposal, leather, cosmetic manufacturing, as an experiment material by repeatedly inhaling and exposure the male S.D. rats at a 0.00, 0.2., 0.50, 1.25 mg/㎡ concentration(particle size: 0.5-0.5 aerosol)6hours a day, 5day a week in 13weeks comparing with 2weeks, 8weeks of recovery group about the noxiousness of the experiment animal and the reduce scale of the CrO3 in the internal organ especially in blook and respiratory organ with the period of convalescent and clearance. The experiment results which we received are as follows. 1. In blood the RBC, HGB and HCT experiment, rats with 0.20, 0.50 mg/㎡ concentration showed that there were some decreases but not dependent. The kidneys absolute weight compared with control group was reduced intentionally(p〈0.05) and the lungs absolute weight compared with control group showed intentional increase(p〉0.05). 2. After the exposure of the experiment material, the whole blook, l\blood plasma and red blood cell in blood by (x): the period of convalescent, per (y); the decreasing of Cr concentration, was y=66.51 e -0.057x, y=67.2 e-0.101x, y=70.01 e-0.030 in 0.50 mg/㎡ exposure concentration by calculating the clearance coefficient of correlation, and the half life (day)was estimated 12.0, 6086, 23.0 each. 3, After the exposure of the experiment material, the experiment animals lung, liver and kidneys by(x); the period of convalescent, per (y); the decreasing of Cr conentration, was y=1808 e-0.00493x, y=12.02e-0.0297x, y=67.61 e-0.0292x in 0.50mg/㎡ exposure concentration by calculating the clearance coefficient of correlation, and the half life(day)was estimated 140.6, 23.3, 23.7, each, and including lung, liver with all of the experiment internal organs, the Cr clearance decreased as the exposure concentration increased.

      • Antioxidant activity in vitro and mucosal protective effect of Rhei Rhizoma on reflux esophagitis induced in rats

        Ah Reum Lee,Yu Ock Shin,Joo Young Lee,Min Yeong Kim,Sung Ho Shin,Bu-Il Seo,Young-Bae Seo,Man Hee Rhee,TakakoYokozawa,Chan Hum Park,Seong-SooRoh 한국약용작물학회 2015 한국약용작물학술대회 발표집 Vol.2015 No.05

        Purpose Rhei Rhizoma (RR) is one of the herbal medicines traditionally used to treat diverse inflammatory diseases. The present study was undertaken to elucidate the antioxidant and anti-inflammatory activities of Rhei Rhizoma on experimental reflux esophagitis (RE) in rats. Methods The antioxidant activity of RR in vitro was measured in terms of radical scavenging capacity such as DPPH and ABTS. RE was produced by ligating both the pylorus and the transitional junction between the forestomach and the corpus. Rhei Rhizoma (125 and 250 mg/kg) were administered every day for 7 days, and its effect was estimated on comparison with RE control and normal rats. Results RR scavenged DPPH and ABTS effectively and IC50ofDPPH and ABTS radical scavenging activity of RR were 4.8 μg/ml and 15.75 μg/ml. The administration of RR decreased the elevated serum ROS in RE control rats. The RE control rats exhibited the down-regulation of antioxidant-related proteins such as Nrf2 and HO-1expression levels in the esophagitis; however, the level in the RR-treated RE rats was significantly higher than that in the RE control rats. Moreover, RE control rats exhibited the up-regulation of the protein expression related to oxidative stress at the esophagitis, but RR administration significantly reduced the expression of inflammatory proteins through the MAPK-independent signaling pathways. The expression of inflammatory mediators and cytokines by NF-κB activation was modulated through blocking the degradation of IκBα. In addition, the oral administration of RR regulated the gastric mucosal damage in RE rats. Conclusion The administration of Rhei Rhizoma effectively ameliorates the inflammatory damage of esophageal mucosa through radical scavenging activity and the activation of the Nrf2/HO-1 pathway.

      • Protective Effects of Hyperoside against Carbon Tetrachloride-Induced Liver Damage in Mice

        Choi, Jun-Ho,Kim, Dong-Wook,Yun, Nari,Choi, Jae-Sue,Islam, Md. Nurul,Kim, Yeong-Shik,Lee, Sun-Mee American Chemical Society and American Society of 2011 Journal of natural products Vol.74 No.5

        <P>In this study, the hepatoprotective effects of hyperoside (<B>1</B>), a flavonoid glycoside isolated from <I>Artemisia capillaris</I>, have been examined against carbon tetrachloride (CCl<SUB>4</SUB>)-induced liver injury. Mice were treated intraperitoneally with vehicle or <B>1</B> (50, 100, and 200 mg·kg<SUP>−1</SUP>) 30 min before and 2 h after CCl<SUB>4</SUB> (20 μL·kg<SUP>−1</SUP>) injection. Levels of serum aminotransferases were increased 24 h after CCl<SUB>4</SUB> injection, and these increases were attenuated by <B>1</B>. Histological analysis showed that <B>1</B> prevented portal inflammation, centrizonal necrosis, and Kupffer cell hyperplasia. Lipid peroxidation was increased and hepatic glutathione content was decreased significantly after CCl<SUB>4</SUB> treatment, and these changes were reduced by administration of <B>1</B>. Protein and mRNA expression of tumor necrosis factor-α (TNF-α), inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and heme oxygenase-1 (HO-1) and nuclear protein expression of nuclear factor erythroid 2-related factor 2 (Nrf2) significantly increased after CCl<SUB>4</SUB> injection. Compound <B>1</B> suppressed TNF-α, iNOS, and COX-2 protein and mRNA expression and augmented HO-1 protein and mRNA expression and Nrf2 nuclear protein expression. These results suggest that <B>1</B> has protective effects against CCl<SUB>4</SUB>-induced acute liver injury, and this protection is likely due to enhancement of the antioxidative defense system and suppression of the inflammatory response.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jnprdf/2011/jnprdf.2011.74.issue-5/np200001x/production/images/medium/np-2011-00001x_0006.gif'></P>

      • SCISCIESCOPUS

        Protective Effect of Baicalin Against Carbon Tetrachloride–Induced Acute Hepatic Injury in Mice

        Park, Sang-Won,Lee, Chan-Ho,Kim, Yeong Shik,Kang, Sam Sik,Jeon, Su Jin,Son, Kun Ho,Lee, Sun-Mee The Japanese Pharmacological Society 2008 JOURNAL OF PHARMACOLOGICAL SCIENCES Vol.106 No.1

        <P>This study examined the effects of baicalin, a bioactive flavonoid isolated from <I>Scutellariae Radix</I>, on carbon tetrachloride (CCl<SUB>4</SUB>)-induced liver injury. Mice were treated intraperitoneally with 0.5 ml/kg CCl<SUB>4</SUB> and different groups of animals received 25, 50, 100, and 200 mg/kg baicalin. At 24 h after the CCl<SUB>4</SUB> treatment, the level of serum aminotransferases and lipid peroxidation was significantly elevated, whereas the hepatic glutathione content was decreased. These changes were attenuated by baicalin. The histological studies showed that baicalin inhibited the portal inflammation, centrizonal necrosis, and Kupffer cell hyperplasia, which are the three most common characteristics of CCl<SUB>4</SUB>-induced liver damage. The serum level and mRNA expression of tumor necrosis factor-α were markedly increased by the CCl<SUB>4</SUB> treatment but suppressed by baicalin. The mRNA and protein expression levels of inducible nitric oxide synthase and heme oxygenase-1 increased significantly at 24 h after the CCl<SUB>4</SUB> treatment. Baicalin attenuated the increase in the protein and gene expression of inducible nitric oxide synthase but augmented the increase in those of heme oxygenase-1. These findings suggest that baicalin protects hepatocytes from the oxidative damage caused by CCl<SUB>4</SUB>, and this protection is likely due to the induction of HO-1 expression and the inhibition of the proinflammatory mediators.</P>

      • 플라즈마 표면처리 기법에 의한 무기절연물 표면상의 젖음성 향상에 관한 연구

        이종호,엄무수,황영한 울산대학교 1994 공학연구논문집 Vol.25 No.2

        본 연구는 유리섬유 강화 복합재료(GFRP)의 최적제작조건을 규명하기 위한 기초연구로서, 플라즈마 발생장치의 최적조건을 규명하고, 에폭시 수지와 유리섬유 사이의 계면현상을 표면처리 조건에 따라 각각 접촉각 변화과정을 측정하였다. GFRP의 필라(filler)표면처리는 열처리, 실란 결합제 처리, 플라즈마 처리를 했고 플라즈마를 발생시키기 위한 주위환경은 공기로 했다. 표면처리 한 무기절연물 표면에서 에폭시 수지상의 접촉각은 표면처리 조건에 따라 다르게 나타났고 특히, 플라즈마 처리시간과 전기로 내부 주위온도에 크게 영향을 받고 있음을 알 수 있었다. 본 연구에서 플라즈마 처리시간과 전기로 내부 주위온도의 관점에서 80℃일때는 3분, 100℃일때는 4분, 120℃일때는 5분일때 접촉각 특성이 가장 우수하게 나타남을 알 수 있었다. With the contact angle of phase epoxy resin on the inorganic filler(glass plate) surface treated with air plasma, we have studied about the interface between epoxy resin and glass plate as a simple model of glass fiberreinforced composite materials(GFRP). The contact angle on the inorganic filler surface varied with surface treatment conditions . The contact angle significantly depends on plasma treating time and environment temperature of the oven. From the view point of plasma treatment condition in this work, optimum treatment time were proved as 3, 4 and 5 minutes for the treatment temperatures of 80℃, 100℃ and 120℃, respectively.

      • KCI등재

        아동의 하악골에 발생한 복합 치아종의 외과적 처치에 관한 증례보고

        이긍호,최영철,정우성 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.3

        악골에서 비교적 흔한 빈도로 발생하는 치아종은 치배조직의 과성장으로 인하여 발생한다.세계보건기구에서는 치아종을 복잡 치아종과 복합 치아종으로 구분하고 있다.치아종은 악골내 모든 부위에서 발생할 수 있지만 치아와 유사한 복합 치아종은 비교적 상악 전치부에 호발하고,불규칙한 형태를 나타내는 복잡 치아종은 하악 구치부에 호발한다.치아종의 원인은 정확히 알려져 있지 않으며 치배에 대한 구소적인 외상이나 감염이 주된 요인으로 추측되고 있고,최근에는 유전적인 원인에 대해서도 연구되고 있으나 아직 확실히 입증되지는 않고 있다.일반적인 증상이 없기 때문에 일상적인 방사선 검사에서 주로 발견되고 영구치의 맹출지연이나 유치의 만기잔존 등이 증상이 있을 수 있다.치아종은 구강내의 어떤 부위에서도 발생이 가능하고 드물기는 하지만 상악동,하악의 하연,하악지 및 하악과두 하방에서 발견되기도 하며,이공 부위에서 발생되는 경우도 있다. 치아종은 발육중인 치열과 악궁에 미치는 영향을 최소화하기 위하여 발견되는 즉시 낭포 및 주위 연조직을 함께 외과적으로 제거하는 것이 바람직하다.환자의 연령과 치과치료에 대한 협조도,영구치열의 발육상태,치아종의 악골내 위치 및 동시적인 치과치료가 요구되는 가를 고려하여 외래 진료실에서 하는 경우도 있고 전신마취를 통하여 하는 경우도 있다. 본 증례는 치아종의 악골내 위치가 깊지 않고 치과치료에 대한 협조도가 양호하다고 판단되는 환아에서는 외래 진료실에서 국소마취하에 수술하여 치료하였고,연령이 어리고 치아종이 악골내 위치가 깊어 장시간의 시술 시간이 요구되고 동시에 보존적인 치과치료가 필요한 환아에서는 전신마취하에 치료한 것을 보고한 것이다.두 증례에서 수술 4개월 후 외과적 결손 부위에 골이 형성되었고,매복된 영구치의 맹출이 정상적으로 이루어진 것으로 나타났다. The Odontogenic is relatively a common benign odontogenic tumor and caused by overgrowth of odontogenic tissues.The recent classification by World Health Organization divides odontoma into 2 groups such as compound odontoma and complex odontoma.Compound odontoma comprises dental tissues,resembling the morphology of a tooth and has predilection for the anterior maxilla.In contrast,complex odontoma has unorganized mass,not resembling the normal tooth and has predilection for the posterior mandible.The etiology of odontoma is unknown and almost asymptomatic.So,it usually is found in routine radiographic examination,and most common presenting symptom is impacted or unerupted permanent teeth and ratained primary teeth.It can occurs almost anywhere in jaws. It is desirable that odontoma should be removed by surgical enucleation including follicle and surrounding soft tissues.Considering the age and behavioral cooperation of patient,the develoment of parmanent dentition,the location of odontoma in jaw,the need for the concomitant operative dentistry,operation is performed in outpatient department with/without sedation or under general anesthesia with endotracheal intubation. In this case report,2 patients with compound odontoma were treated by surgical enucleation including follicle and surrounding soft tissues.One patient,about 5years old,was treated under general anesthesia and concomitant operative density was performed.The other patient,about 11years old,was treated under local anesthesia in outpatient department.In 2 cases,after 4 months,surgical defects were filled with new bone and normalization of eruption path of impacted permanent teeth was observed.

      • KCI등재

        외상에 의해 설측 변위된 하악 제1유구치의 가철성 장치를 이용한 치료

        이명성,이긍호,최영철,박재홍 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.1

        유치열에서 가장 외상이 호발하는 부위는 상악 유중절치이며, 영구치열에서 치관부 파절이 많이 나타나는 것과는 달리, 정출, 함입, 측방 변위, 탈구 등 지지조직에 한정된 손상이 많이 나타난다. 그러나, 유구치는 외상에 의해 손상을 받는 경우가 매우 드물게 보고되고 있으며, 단일 치아 또는 다수 치아의 파절이 주를 이루고 있다. 즉, 탈구 또는 변위되는 경우가 매우 드물고 이러한 경우의 치료에 대한 보고도 거의 없다. 본 증례는 4세 5개월 된 여아에서 외상으로 인해 하악 좌측 유측절치의 정출, 유견치의 탈구와 함께 제1유구치의 설측 변위가 발생하였는데, 계승 영구치의 맹출 시기와 환아의 협조도를 고려하여 가철성 장치를 이용한 하악 제1유구치의 재위치를 시도하여 양호한 결과를 얻었기에, 유구치의 외상으로 인한 변위 시 치료 방법의 선택에 도움이 되고자 보고하는 바이다. In the primary dentitions, the majority of dental injuries involve the anterior teeth, especially the maxillary primary central incisors. When injuries affecting primary and permanent teeth are compared, it appears that trauma to the primary dentition is usually confined to the supporting structures, i.e. luxation and exarticulation, while the largest proportion of injuries affecting the permanent dentition is represented by crown fractures. But, cases reporting trauma affecting primary molars are unusual in the literature and several reports describe fractures of posterior teeth. The main goal of this report is to describe the repositioning treatment using removable appliances to an uncommon case of lingual displacement of primary molar that happened to a 4 year 5 month-old female child.

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