전기 기계적 해리로부터 회복된 쯔쯔가무시병에서의 급성 전격성 심근염

정영학,이민주,이경화,이지훈,김석형,이병권 이화여자대학교 의과학연구소 2016 EMJ (Ewha medical journal) Vol.39 No.1

Scrub typhus, caused by Orientia tsutsugamushi , is an acute febrile illness. Characteristics of tsutsugamushi disease are fever, rash and eschar. However, severe complications might rarely occur, such as acute fulminant myocarditis caused by scrub typhus. Thus, there are few reports of recovery from seriously complicated cases. We report on an adult male with scrub typhus complicated with acute fulminant myocarditis with no previous comorbid illness who recovered successfully with proper treatment including antibiotics, ventilator support, percutaneous cardiopulmonary support, and continuous renal replacement therapy.

우울증 환자 치료에 있어서 Tianeptine과 Sertraline의 효과와 안전성 비교

이민수,강성민,기백석,연병길,오병훈,이철,채정민,백인호 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.2

연구목적: 주요 우울증의 치료에 있어서 티아넵틴과 써트랄린의 임상적 효과와 안정성을 비교하기 위하여 연구를 시행하였다. 방법: DSM-IV 진단 기준에 의거하여 주요 우울증의 진단기준에 부합되고 17항목 해밀턴 우울척도 점수가 14점 이상인 환자를 대상으로 하였다. 총 40명의 환자를 무작위적 방식에 따라 티아넵틴 치료군과 써트랄린 치료군으로 분류하였다. 선탠된 환자에서 다른 항우울제를 복용하고 있는 경우 7일 이상의 약물 배설기간을 가진 후 티아넵틴과 써트랄린을 각각 6주간 투여하였으며, 기준점, 1주후, 2주 후, 4주 후, 6주 후에 HAM-D, MADRS, 그리고 CGI, COVI 등을 사용하여 평가하였다. 본 연구기간 중 발생된 모든 부작용은 부작용의 발생 및 소실 시기, 심한 정도, 발생 빈도, 관련 조치 및 결과에 대하여 증례기록서에 기록하도록 하였다. 결과: 30명(티아넵틴군 15명 ; 써트랄린군 15명)이 6주간의 연구를 완결하였고 티아넵틴 치료군에서는 1일 37.5mg을 투여하였으며 써트랄린군에서는 1일 평균 64.0±22.5mg을 투여하였다. 본 연구 결과 HAM-D, MADRS, CGI 상에서 두 군 모두에서 치료 1주 후부터 유의한 감소를 나타내었으며 이는 2주 후, 4주 후, 6주 후에도 지속적인 감소를 보였고 두 군간에 항우울 효과의 차이는 없었다. 활력징후, 일반 혈액학, 생화학, 심전도 검사 등에서는 두 군 모두 유의한 변화는 없었다. 티아넵틴과 관련된 부작용으로 흔히 보고한 증상은 오심(33.3%), 복부 불쾌감(26.7%), 구강 건조(20.0%), 두통(13.3%)등 이었고 써트랄린 치료군에서는 구강 건조(53.3%), 두통(46.7%), 오심(33.3%), 그리고 식욕 부진(33.3%)등으로 티아넵틴군에서 보다 적은 발현빈도를 보였다. 결론: 티아넵틴은 우울증의 치료에 있어서 효과적이고, 내약성이 우수한, 안전한 항우울제이다. Objective: This study was designed to evaluate the efficacy and safety of tianeptine and sertraline in the treatment of patients with depression. Method: The study was done on the patients with major depression diagnosed by DSM-IV, who had aHamilton Rating Scale for Depression(HAM-D) score ≥ 14 on the first 17 items of the HAM-D. A total of 40 patients were randomly assigned to tianeptine group and sertraline group. Tianeptine and sertraline were prescribed to each group. 6 weeks of each medication was carried out after 7 days of drug excretion period. Evaluation using 17 item HAM-D, Montgomery and Åsberg Depression Rating Scale(MADRS), Clinical Global Impression Scale (CGI), and Covi Scale was done on the baseline and after 1 week, 2 weeks, 4 weeks, and 6 weeks. Regrding all side effects that had occurred during the period of our study such as their developed/disappeaed time, severitien, incidences, managements and results have been recorded. Results: A total of 30 patients(tianeptine group 15 ; sertraline froup 15) finished the 6 weeks of research. 37.5mg of the daily dose was regularly prescribed to the tianeptine group, the average amount of 64.0±22.5mg of the final daily dose was prescribed to the sertraline group. Total 17 item HAM-D scores, total points of MADRS and CGI showed significant decrease after 1 week in each treatment froup and continous decrease after 2, 4 and 6 weeks ; and no difference was found between tianeptine group and sertaline group in the antidepressant efficacy. Also there were no significant changes in vital sign, CBC, chemistry, and EKG in each treatment group. The common reported side effects of tianeptine were nausea(33.3%), epigastic distress(26.7%), dry mouth(20.0%), headache(13.3%) and those of sertraline were dry mouth (53.3%), headache(46.7%), nausea(33.3%), anorexia(33.3%). Conclusion: According to the results, tianeptine was effective in improvement of depressive symptoms and was well tolerated and safe in patients with depression.

클러스터형 VOD서버에서 고가용성을 고려한 자체 복구 시스템

이좌형,서동만,방철석,김병길,정인범 강원대학교 정보통신연구소 2004 정보통신논문지 Vol.8 No.-

While clustered VOD (Video On Demand) servers that have been proposed for building large-scale VOD system recently, have the advantages of high availability and scalability, the system level reliability of the clustered VOD servers could be decreased by adding more servers to scale up the capacity of the server. To alleviate this reliability problem and support server-level fault tolerance, this paper proposes and analyzes self recovery system based on RAID-3 and 4 with pipelining concept. The proposed self recovery system could increase the efficiency of the disk by accessing the disk with large size block as in RAID-4. The network resource could be used efficiently and the workload of memory could be decreased by sending data in small size block as in RAID-3. By introducing pipeline concept, the recovery tasks are processed at several nodes in parallel so that the workload in CPU, network, and memory could be distributed to several nodes.

퍼지 제어기의 함수 구성 능력에 관한 연구

이지홍,오영석,정병현 金烏工科大學校 1991 論文集 Vol.12 No.-

Fuzzy controller has been successfully applied to many cases to which conventional control algorithms are difficult to be applied. This is due to the uncertainty handling capability of fuzzy controller. In spite of the special internal processing mechanisms, the fuzzy controller is basically a crisp mapping from n dimensional space to m dimensional space; n and m are the numbers of output and input variable of the controlled system, respectively. The approximating capability the fuzzy controller with a given mapping, is studied in this paper.

100m 단거리 출발 구간에 대한 운동학적 분석

이강우,강관희,안병석 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

The purpose of this study was to find the most important kinematic parameters of the starting phase. For three dimension motion analysis, Four video cameras used to take a picture the man's high school department final game in 33th spring season junior and higher school athletic contest. The analysis subjects choose from rank 1 to 5 in the final game. The kinematic variables analyzed the time, velocity ad angles about three stride. The result were as follows; 1) For the faster velocity in the starting phase, the subjects appeared to do landing in a short stride on the first foot and the support time after landing. 2) For the faster velocity in the starting phase, the subjects appeared to do take a slowly change in a front lean angle of the trunk during stride. 3) For the faster velocity in the starting phase, The subjects appeared to do increase rotation force through a fast flexion and extension in the hip and knee joint. Especcially, all the subjects appeared to do increase a fast flexion and extension in more the right leg than the left leg.

경상분지 남동부에 분포하는 화강암질암의 광물학적 특징

황병훈,이준동,양경희,옥수석 한국광물학회 2004 광물과 암석 (J.Miner.Soc.Korea) Vol.17 No.4

경상분지 남동부에 분포하는 화강암질암은 야외산상 및 암석기재적 특징에 따라 크게 세 그룹으로 나눌 수가 있다. 즉, 그룹Ⅰ은 마그마혼합의 영향을 받은 암체로 염기성 미립 포유암 및 염기성광물 집합체를 다양하게 함유한다. 그룹Ⅱ는 낮은 압력하에서 형성된 천소관입암의 특징을 나타내며, 그룹Ⅲ은 A-형 화강암류의 특징을 보인다. 화강암질암의 광물학적 특징을 각 광물에 대하여 암상별로 살펴본 결과, 그룹에 따라 장석의 용리온토 및 흑운모의 성분 등에서 비교적 체계적인 성분변화를 보여주었다. 각섬석의 경우, 그룹Ⅰ의 암상들은 칼식-각섬석 영역에 속하며 각섬석 지압계에 의한 추정압력은 0.4~2.8 kb에 해당되었다. 그룹Ⅱ에서는 각섬석이 거의 산출되지 않았고, 그룹 Ⅲ의 각섬석은 알칼리-각섬석 영역의 리베카이트에 해당되었다. 흑운모의 화학조성은 비교적 그룹별로 군집을 잘 이루며, 그룹Ⅰ에서부터 그룹Ⅲ의 철질-앤나이트까지 연속적인 변화양상을 보여주었다. 사장석은 지역 및 암상별로 뚜렷한 차이를 나타내지 않으며, 대체로 알바이트, 올리고클레이스, 그리고 안데신의 영역에 해당된다. 그룹별로 퍼타이트 지온계에 의한 용리 온도를 검토한 결과, 그룹Ⅰ은 대체로 300~400℃ 정도이며, 그룹Ⅱ의 등립질화강암과 그룹Ⅲ의 알칼리장석화강암은 500~600℃ 정도로 높게 나타났다. Granitic rocks in the southeastern Gyeongsang. Basin can be classified into three groups. The group Ⅰ contains various mafic microgranular enclave (MME) and/or mafic clot which implies magma mixing or mingling. The group Ⅱ show the feature of shallow depth emplacement at low pressure, and the group Ⅲ is characterized by A-type granite implying extensional tectonic environment. Mineralogical characteristics of the granitic rocks have showed systematic variations in perthite exsolution temperatures and biotite compositions according to their rock facies, although they do not show any distinctively different trend in geography and textures or rock facies. Amphiboles from Group Ⅰ are calcic-amphibole and they were formed at 0.4~2.8 kb in pressure based on the amphibole geobarometry. Amphiboles from group Ⅲ are riebeckite, whileas amphiboles were not observed in Group Ⅱ The chemical composition of biotite defined in clusters showing a continuous spectrum between group Ⅰ to ferric-annite of group Ⅲ. The composition of plagioclase generally plotted in albite, oligoclase, and andesine area without any distinctive differences among their geography or rock facies. The exsolution temperatures by perthite geothermometry are calculated as 300~400℃ in Group Ⅰ, and 500~600℃ in equigranular granite of group Ⅱ and alkali-feldspar granite of group Ⅲ.

기도 이물의 임상적 고찰

김영석,이승규,이민재,백병준,오천환 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.2

Aspiration of foreign bodies into the airway is a common problem in spite of efforts to educate the public and it can be sometimes fatal accidents. A retrospective study has been performed for 34 cases of airway foreign bodies, which were obtained from April 1994 to August 1998 at Chunan hospital of Soonchunhyang University. The results were as follows: 1) Among the 34 cases, 26 cases(76.4%) were under the age of 3. The ratio of male and female was 1.4:1. 2) The most common symptom after foreign body aspiration was intractable cough(38.2%). 3) Abnormal findings in the chest X-ray films were found 24 cases(70.6%) and the most common abnormal radiologic feature was combination of pneumonia and atelectasis(37.5%), followed by combination of pneumonia and emphysema(16.6%), pneumonia alone(16.6%). 4) The nature of foreign body was vegetables in 20 cases(58.8%), miscellaneous in 11 cases(32.4%), metals in 2 cases(5.9%) and plastics in 2 cases(5.9%). 5) By distribution of the location of foreign bodies, 26 cases(76.4%) were located in the main bronchus(20 cases in right side and 6 cases in left side), 5 cases were in trachea, 2 cases were in larynx and 1 case was located at carina level. 6) By duration of foreign body lodgement in the airway, 15 cases(44.1%) were found within 24 hours, 9 cases(26.5%) were within 7 days, 7 cases(20.6%) were within 30 days and 3 cases(8.8%) were found over 1 month. 7) In mode of treatment, ventilating bronchoscopic removal under general anesthesia was performed in 29 cases(85.3%), thoracotomy with bronchotomy in 2 cases, thoracotomy with lobectomy in 1 case and postural drainage in 2 cases. 8) Complication rate according to the nature of foreign body was most high in vegetables(68.2%). 9) Correlation between complication rate and the duration of the foreign bodies in situ was definite.

외상성 경막하수종 환아에서 조기 수술의 유용성

김병욱,이승명,김석원,김현성,신호 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.3

Background and Objectives: This study was performed to evaluate the usefulness of early operation in children with traumatic subdural hygroma. Materials and Methods: The subjects were eleven patients (Glasgow coma scale (GCS) score was below 10 and age was below 10 years old) who developed subdural hygroma after trauma between January 2000 to December 2002. Subduroperitoneal shunt was performed in one group and not performed in the other group. We analyzed the GCS score on admission and at 1 year after operation. Overall clinical results were evaluated retrospectively. Results: Patients who underwent operation exhibited higher GCS scores at 1 year after trauma compared to those in the patients who were treated by conservative therapy (p<0. 05). Conclusion: The early operation could be an effective treatment to children with subdural hygroma who showed delayed improvement of consciousness and to patients with hygroma that didn't decrease or was above moderate amount.

교정용 고무 링의 삽입과 임시 전장관의 수정을 통한 보철 수복 전 인접면 공간 획득: 증례보고

신한얼,노병덕,신유석,이찬영 大韓齒科保存學會 2012 Restorative Dentistry & Endodontics Vol.37 No.2

Proximal caries or coronal defect in posterior teeth may result in the loss of proximal space and drifting of neighboring teeth, which makes restoration difficult. Inability to restore proper contours and to align tooth axis properly are commonly encountered problems when planning tooth restoration. Moreover, tilted teeth aggravate periodontal tissue breakdown, such as pseudo-pocket, and angular osseous defect. The purpose of this case presentation is to describe a simple technique for inducing minor tooth movement with orthodontic separating ring and provisional restoration modification. This method was used to create crown placement space on mesially tilted molar. This method is easy, simple and efficient technique which could be used in interproximal space gaining in selected situation.

PVDF 및 P(VDF-TrFE)를 이용한 고주파수 수침용 초음파 탐촉자 개발 및 평가

김기복,김병극,이승석 한국비파괴검사학회 2002 한국비파괴검사학회지 Vol.22 No.1

PVDF 및 P(VDF-TrFE) 고분자 압전박막을 이용하여 고주파수 수침용 초음파 탐촉자를 제작한 다음 그 특성을 비교 ㆍ 평가하였다. 탐촉자와 탐상기 사이의 신호전송용 동축케이블의 길이가 고주파수 초음파 검출장에 영향을 미치는 것으로 나타났다. 초음파 빔의 초점이 형성되는 반사체가 편평할수록 고주파수 초음파 검출장은 감소하는 것으로 나타났으며 3mm 직경의 PVDF 탐촉자의 경우 0.5mm 강구에서 약 100MHz의 광대역 고주파수 초음파 검출장을 형성하였다. PVDF와 P(VDF-TrFE) 탐촉자를 비교한 결과 반사신호의 피크 값과 빔 폭은 P(VDF-TrFE)가 PVDF 보다 크게 나타났으나 고주파수 초음파 검출장은 PVDF가 P(VDF-TrFE)보다 광대역 특정을 나타내었다. 개발된 3mm 직경의 PVDF 탐촉자를 이용하여 표면의 깊이균열 크기가 30∼100μm인 수소유기균열(HIC) 강재 시편을 C-scan한 결과 고감도의 분해능으로 미세 균열의 검출이 가능하였다. The high frequency ultrasonic transducers using polyvinyliden fluoride(PVDF) and polyvinylidene fluoride trifluorethyylene (P(VDF-TrFE) were developed. The characteristics of fabricated high frequency ultrasonic transducer such as beam diameter, high frequency ultrasonic detection field and amplitude of the first pulse echo signal from the test target in the water were analyzed. The high frequency ultrasonic detection field was affected by the length of coaxial cable between high frequency transducer and ultrasonic pulser/receiver. As the size of the test target increased, the high frequency detection field decreased and the amplitude of a reflection signal increased. The peak amplitude of the first pulse echo signal of P(VDF-TrFE) transducer was higher than that of PVDF transducer. The high frequency ultrasonic detection field of PVDF transducer was wider than that of P(VDF-TrFE) transducer. With C-scan testing, the developed high frequency ultrasonic transducer could detect the 30 to 100㎛ of hydrogen induced crack of steel specimen by C-scan testing.